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Article ; Online: Comment on: The perfect stoma: tips from a stoma nurse.

Pata, Francesco / Parini, Dario / Rizzo, Gianluca / Bondurri, Andrea / Ferrara, Francesco

2024 Volume 111, Issue 1

MeSH term(s)	Humans ; Surgical Stomas ; Preoperative Care
Language	English
Publishing date	2024-01-01
Publishing country	England
Document type	Journal Article
ZDB-ID	2985-3
ISSN	1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
ISSN (online)	1365-2168
ISSN	0263-1202 ; 0007-1323 ; 1355-7688
DOI	10.1093/bjs/znae011
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Article ; Online: Emergency surgical treatment of colonic acute diverticulitis: a multicenter observational study on behalf of the Italian society of colorectal surgery (SICCR) Lombardy committee.

Ferrara, Francesco / Guerci, Claudio / Bondurri, Andrea / Spinelli, Antonino / De Nardi, Paola

Updates in surgery

2023 Volume 75, Issue 4, Page(s) 863–870

Abstract: Colonic diverticulitis can be treated conservatively, but some cases require surgery. Patients can undergo Hartmann's procedure (H) or resection with primary anastomosis (RA), with or without diverting stoma. This multicenter observational retrospective ... ...

Abstract	Colonic diverticulitis can be treated conservatively, but some cases require surgery. Patients can undergo Hartmann's procedure (H) or resection with primary anastomosis (RA), with or without diverting stoma. This multicenter observational retrospective study aims to evaluate the adherence to current guidelines by assessing the rate of RA and H in Lombardy, Italy, and to analyze differences in patients' features. This study included data collected from nine surgical units performing emergency surgery in Lombardy, in 2019 and 2021. Data for each year were retrospectively collected through a survey among Italian Society of Colorectal Surgery (SICCR) Lombardy members. Additional data were about: Hinchey's classification, laparoscopic (VLS) or converted procedures, procedures with more than two operators, procedures in which the first operator was older than 40 years, night or weekend procedures, older-than-80 patients, COVID-19 positivity (just 2021). The total number of operations performed was 254, 115 RA and 130 H (45.3% and 51.2%, diff. 12%, p = 0.73), and 9 (3.5%) other procedures. RAs were more frequent for Hinchey 1 and 2 patients, whereas Hs were more frequent for Hinchey 3 and 4. RAs without ileostomy were significantly less than Hs (66 vs. 130, p = 0.04). Laparoscopy was more used for RA compared to H (57 vs. 21, p = 0.03), whereas no difference was found between RA and H with respect to conversion rate, the presence of more than two operators in the team, the presence of a first operator older than 40 years, night or weekend operations, and for older-than-80 patients. This study confirms the adherence to current guidelines for the treatment of acute colonic diverticulitis in Lombardy, Italy. It can be considered as a preliminary survey with interesting results that may open the way to a further prospective observational study to clarify some aspects in the management of this disease.
MeSH term(s)	Humans ; Diverticulitis, Colonic/surgery ; Retrospective Studies ; Colorectal Surgery ; COVID-19 ; Diverticulitis/surgery ; Colostomy ; Anastomosis, Surgical/methods ; Laparoscopy/methods ; Intestinal Perforation/surgery ; Treatment Outcome ; Peritonitis/surgery
Language	English
Publishing date	2023-03-19
Publishing country	Italy
Document type	Observational Study ; Multicenter Study ; Journal Article
ZDB-ID	2572692-4
ISSN	2038-3312 ; 2038-131X
ISSN (online)	2038-3312
ISSN	2038-131X
DOI	10.1007/s13304-023-01487-7
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Article ; Online: 3D fluoroscopy reconstruction for lead placement in sacral neuromodulation-A video vignette.

Bondurri, Andrea / Simone, Michela Del / Maffioli, Anna / Naclerio, Michele / Rech, Roberto / Danelli, Piergiorgio

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

2023 Volume 26, Issue 1, Page(s) 217–218

MeSH term(s)	Humans ; Electric Stimulation Therapy ; Electrodes, Implanted ; Sacrum/surgery ; Fluoroscopy
Language	English
Publishing date	2023-12-03
Publishing country	England
Document type	Video-Audio Media ; Letter
ZDB-ID	1440017-0
ISSN	1463-1318 ; 1462-8910
ISSN (online)	1463-1318
ISSN	1462-8910
DOI	10.1111/codi.16828
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Article: A rare but life-threatening complication of aortic surgery: iliac appendiceal fistula

Bondurri, A. / Zampino, L.

European surgery

2017 Volume 49, Issue 5, Page(s) 248

Language	English ; German
Document type	Article
ZDB-ID	2073941-2
ISSN	1682-8631 ; 1682-1769
Database	Current Contents Medicine

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Article ; Online: Pelvic floor dysfunction in inflammatory bowel disease.

Bondurri, A / Maffioli, A / Danelli, P

Minerva gastroenterologica e dietologica

2015 Volume 61, Issue 4, Page(s) 249–259

Abstract: Advances in tailored medical therapy and introduction of biologic agents for inflammatory bowel disease (IBD) treatment have ensured long-term disease remission. Some patients, however, still report defecatory symptoms. Patients present with a wide ... ...

Abstract	Advances in tailored medical therapy and introduction of biologic agents for inflammatory bowel disease (IBD) treatment have ensured long-term disease remission. Some patients, however, still report defecatory symptoms. Patients present with a wide spectrum of conditions - anal incontinence, obstructed defecation and pelvic pain among the most frequent - that have a great impact on their quality of life. Due to IBD diagnosis, little relevance is attributed to this type of symptoms and their epidemiologic distribution is unknown. Pathogenetic hypotheses are currently under investigation. Routine diagnostic workflow and therapeutic options in pelvic floor service are often underused. The evaluation of these disorders starts with an endoscopy to rule out ongoing disease; the following diagnostic workflow is the same as in patients without IBD. For fecal incontinence and obstructed defecation, simple conservative therapy with dietary modifications and appropriate fluid intake is effective in most cases. In non-responding patients, anorectal physiology tests and imaging are required to select patients for pelvic floor muscle training and biofeedback. These treatments have been proven effective in IBD patients. Some new minimally invasive alternative strategies are available for IBD patients, as sacral nerve and posterior tibial nerve stimulation; for other ones (e.g., bulking agent implantation) IBD still remains an exclusion criterion. In order to preserve anatomical areas that could be useful for future reconstructive techniques, surgical options to cure pelvic floor dysfunction are indicated only in a small group of IBD patients, due to the high risk of failure in wound healing and to the possible side effects of surgery, which can lead to anal incontinence or to a possible proctectomy. A particular issue among defecatory symptoms in patients with IBD is paradoxical puborectalis contraction after restorative proctocolectomy: if this disorder is properly diagnosed, a conservative treatment is indicated, thus avoiding unnecessary laparotomy for small bowel occlusion. Pelvic pain management, coordinated by a specialist with expertise in pelvic floor disorders, includes many options, which vary from oral or local therapies to pelvic floor rehabilitation and sacral nerve stimulation. Surgical procedures often have unsatisfactory outcomes. Diagnosis and investigation of anorectal functional disorders in patients with IBD is important in order to implement better-suited diagnostic and therapeutic strategies, so as to avoid unnecessary and potentially detrimental medical and surgical therapies, with the final aim of improving patients' quality of life.
MeSH term(s)	Constipation/diagnosis ; Constipation/physiopathology ; Constipation/therapy ; Fecal Incontinence/diagnosis ; Fecal Incontinence/physiopathology ; Fecal Incontinence/therapy ; Humans ; Inflammatory Bowel Diseases/physiopathology ; Pelvic Floor/physiopathology ; Pelvic Pain/physiopathology ; Pelvic Pain/therapy
Language	English
Publishing date	2015-12
Publishing country	Italy
Document type	Journal Article ; Review
ZDB-ID	1077354-x
ISSN	1827-1642 ; 1121-421X ; 0026-4776
ISSN (online)	1827-1642
ISSN	1121-421X ; 0026-4776
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Article ; Online: Enteral stoma care during the COVID-19 pandemic: practical advice.

Pata, Francesco / Bondurri, Andrea / Ferrara, Francesco / Parini, Dario / Rizzo, Gianluca

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

2020 Volume 22, Issue 9, Page(s) 985–992

MeSH term(s)	Ambulatory Care/methods ; Ambulatory Care Facilities ; COVID-19 ; Delivery of Health Care/methods ; Delivery of Health Care/organization & administration ; Disinfection ; Enterostomy/nursing ; Home Care Services ; Hospitalization ; Humans ; Infection Control ; Italy ; Nurse Specialists ; Personal Protective Equipment ; Risk Assessment ; Surgeons ; Telemedicine/methods ; Telephone ; Ventilation
Keywords	covid19
Language	English
Publishing date	2020-08-25
Publishing country	England
Document type	Journal Article
ZDB-ID	1440017-0
ISSN	1463-1318 ; 1462-8910
ISSN (online)	1463-1318
ISSN	1462-8910
DOI	10.1111/codi.15279
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Article: Stem Cell Injection for Complex Refractory Perianal Fistulas in Crohn's Disease: A Single Center Initial Experience.

Colombo, Francesco / Cammarata, Francesco / Baldi, Caterina / Rizzetto, Francesco / Bondurri, Andrea / Carmagnola, Stefania / Gridavilla, Daniele / Maconi, Giovanni / Ardizzone, Sandro / Danelli, Piergiorgio

Frontiers in surgery

2022 Volume 9, Page(s) 834870

Abstract: From 30 to 70% of patients with Crohn's disease (CD) may develop perianal fistulas during their lifetime. The medical and surgical management of this complication is challenging, and its treatment still gives unsatisfactory results. However, recent ... ...

Abstract	From 30 to 70% of patients with Crohn's disease (CD) may develop perianal fistulas during their lifetime. The medical and surgical management of this complication is challenging, and its treatment still gives unsatisfactory results. However, recent studies on adipose-derived mesenchymal stem cells have proven their anti-inflammatory and immuno-modulatory potential, representing a new promising tool in the treatment of such stubborn disease. We report our initial experience with three patients who had recurrent perianal CD treated with local infiltration of stem cell darvadstrocel (Alofisel). All the patients had a long history of perianal disease refractory to multiple medical and surgical treatments. The preoperative workup included transperineal ultrasound (TP-US), pelvic MRI, and colonoscopy that ruled out active proctitis in all the patients. The post-treatment follow-up included clinical assessment at 1, 3, and 6 months with repeated MRI and TP-US at 6 months. At 6 months, 2 patients had a clinical response despite radiological persistence of fistula tracts, while one patient presented perianal fistula recurrence complicated by perianal abscess. Although our experience is limited to 3 patients and a short follow-up, our results confirm that darvadstrocel injection is a safe procedure, with a good clinical response in most of the patients, but that it apparently had no effect on the anatomical modification of the fistula tracts. Long-term results, with a rigorous assessment of anatomical lesions, are still needed to support the promising data of the literature.
Language	English
Publishing date	2022-02-07
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2773823-1
ISSN	2296-875X
ISSN	2296-875X
DOI	10.3389/fsurg.2022.834870
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Article ; Online: Colonic Acquired Fistulae: The Potential of CT Colonography.

Flor, Nicola / Scolari, Sofia / Liedenbaum, Marjolein / Maconi, Giovanni / Colombo, Francesco / Maffioli, Anna / Bondurri, Andrea / Crespi, Michele

Academic radiology

2022 Volume 30, Issue 5, Page(s) 959–965

Abstract: The diagnosis of colonic fistulae is crucial in defining the best therapeutic approach. Fistulae can be suspected from clinical history or specific symptoms, but imaging plays a key role in confirming the diagnosis. Previous studies described ... ...

Abstract	The diagnosis of colonic fistulae is crucial in defining the best therapeutic approach. Fistulae can be suspected from clinical history or specific symptoms, but imaging plays a key role in confirming the diagnosis. Previous studies described conventional studies with barium as methods of choice for the diagnosis; more recently intestinal ultrasound, CT and MR have been considered promising tests. CT Colonography is the best radiologic test to evaluate the colon, but only few case reports described its role in this setting. Aim of this paper is to highlight the potentials of CT colonography in evaluating patients with suspected colonic fistulae.
MeSH term(s)	Humans ; Colonography, Computed Tomographic/methods ; Colon/diagnostic imaging ; Colonic Polyps/diagnostic imaging ; Colonic Polyps/pathology ; Colonoscopy ; Colorectal Neoplasms/diagnostic imaging
Language	English
Publishing date	2022-08-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	1355509-1
ISSN	1878-4046 ; 1076-6332
ISSN (online)	1878-4046
ISSN	1076-6332
DOI	10.1016/j.acra.2022.07.006
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Article ; Online: Correction to: Transanal irrigation in functional bowel disorders and LARS: short‑term results from an Italian national study.

Falletto, E / Martellucci, J / Rossitti, P / Bondurri, A / Zaffaroni, G / Ascanelli, S / Chimisso, L / Lauretta, A / Mirafiori, M / Clementi, I / Ripetti, V / Luffarelli, P / Cestaro, G / Bottini, C / Bellini, M / Lambiase, C / Di Candido, F / Zattoni, D / Cornaglia, S /

Tonello, P / Zucchi, E

Techniques in coloproctology

2023 Volume 27, Issue 12, Page(s) 1413–1414

Language	English
Publishing date	2023-10-23
Publishing country	Italy
Document type	Published Erratum
ZDB-ID	2083309-X
ISSN	1128-045X ; 1123-6337
ISSN (online)	1128-045X
ISSN	1123-6337
DOI	10.1007/s10151-023-02871-6
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Article ; Online: Transanal irrigation in functional bowel disorders and LARS: short-term results from an Italian national study.

Falletto, E / Martellucci, J / Rossitti, P / Bondurri, A / Zaffaroni, G / Ascanelli, S / Chimisso, L / Lauretta, A / Mirafiori, M / Clementi, I / Ripetti, V / Lufarelli, P / Cestaro, G / Bottini, C / Bellini, M / Lambiase, C / Di Candido, F / Zattoni, D / Cornaglia, S /

Tonello, P / Zucchi, E

Techniques in coloproctology

2023 Volume 27, Issue 6, Page(s) 481–490

Abstract: Purpose: To evaluate the potential benefits associated with the short-term (6 months) treatment with transanal irrigation (TAI) in patients suffering from functional constipation (FC), functional fecal incontinence (FI), and low anterior resection ... ...

Abstract	Purpose: To evaluate the potential benefits associated with the short-term (6 months) treatment with transanal irrigation (TAI) in patients suffering from functional constipation (FC), functional fecal incontinence (FI), and low anterior resection syndrome (LARS). Methods: A multicenter observational study (12 centers; 369 patients) was conducted to assess the following primary and secondary objectives: to evaluate the level of satisfaction regarding bowel control and quality of life (QoL); to evaluate bowel symptoms severity and dropout frequency and reason. To this aim, validated questionnaires were provided to the patients at baseline (T0) and after 6 months of TAI treatment (T6) performed with the medical device Peristeen Results: A 6-month treatment with TAI enabled a statistically significant (p < 0.05) improvement of QoL scores, satisfaction scores regarding bowel control, and severity indexes of disorder-related symptoms in patients suffering from FC, FI, and LARS. Globally, 8.0% of patients discontinued the treatment after 6 months as a result of occurrence of symptoms (2.4%) or other justifications (3.8%) such as personal reasons. None of the dropouts were due to treatment inefficacy. Conclusion: Results of the present study suggest that short-term TAI treatment is beneficial for patients suffering from functional bowel disorders and LARS. Future analysis of prospective data will focus on the clinical outcomes associated with the long-term use (up to 24 months) of TAI when dealing with these types of medical conditions.
MeSH term(s)	Humans ; Quality of Life ; Postoperative Complications ; Prospective Studies ; Rectal Neoplasms ; Irritable Bowel Syndrome/therapy ; Low Anterior Resection Syndrome
Language	English
Publishing date	2023-04-25
Publishing country	Italy
Document type	Multicenter Study ; Observational Study ; Journal Article
ZDB-ID	2083309-X
ISSN	1128-045X ; 1123-6337
ISSN (online)	1128-045X
ISSN	1123-6337
DOI	10.1007/s10151-023-02800-7
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