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  1. Article: Educational disparities in Brazil may interfere with the cognitive performance of Parkinson's disease patients.

    Lima, Danielle Pessoa / Bonfadini, Janine de Carvalho / Carneiro, Alexandre Henrique Silva / de Almeida, Samuel Brito / Viana, Antonio Brazil / Nogueira E Silva, Ana Cecília / Roriz, Jarbas de Sá / Braga, Pedro

    Dementia & neuropsychologia

    2023  Volume 17, Page(s) e20220084

    Abstract: The prevalence of cognitive impairment in Parkinson's disease (PD) is about 20% to 60%. The Mini-Mental Status Examination (MMSE) is the most used cognitive screening test.: Objective: To evaluate the influence of clinical and demographic ... ...

    Abstract The prevalence of cognitive impairment in Parkinson's disease (PD) is about 20% to 60%. The Mini-Mental Status Examination (MMSE) is the most used cognitive screening test.
    Objective: To evaluate the influence of clinical and demographic characteristics, specifically the education level, on the MMSE score in PD patients of a northeast Brazilian sample.
    Methods: We performed a cross-sectional study of 198 PD patients at a Movement Disorders outpatient clinic in Fortaleza, CE, Brazil. Participants were assessed by detailed clinical history, modified Hoehn and Yahr staging (HY), geriatric depression scale (GDS) and MMSE.
    Results: We found that 68% of patients had MMSE scores below the Brazilian thresholds, which were based in Brucki et al. study (2003). There was a statistically significant difference in the bivariate analysis between educational level and cut-off classification for MMSE. More years of formal schooling were associated with more patients scoring below threshold. We found that 75%, 68.8%, and 79.7% of individuals with more than 11, 9 to 11, and 4 to 8 years of formal schooling, respectively, were below the suggested Brazilian Brucki's threshold. GDS and age were negatively correlated with total MMSE and all its domains. There was no correlation between disease duration and MMSE. Subjects with hallucinations had lower scores.
    Conclusion: Most of the sample had lower performance according to Brazilian thresholds, but there was no control group and no neuropsychological test in this study. Further studies in northeast Brazil are needed to review MMSE cut-off values.
    Language English
    Publishing date 2023-11-20
    Publishing country Brazil
    Document type Journal Article
    ISSN 1980-5764
    ISSN 1980-5764
    DOI 10.1590/1980-5764-DN-2022-0084
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Falls in Parkinson's disease: the impact of disease progression, treatment, and motor complications.

    Lima, Danielle Pessoa / de-Almeida, Samuel Brito / Bonfadini, Janine de Carvalho / Carneiro, Alexandre Henrique Silva / de Luna, João Rafael Gomes / de Alencar, Madeleine Sales / Viana-Júnior, Antonio Brazil / Rodrigues, Pedro Gustavo Barros / Pereira, Isabelle de Sousa / Roriz-Filho, Jarbas de Sá / Sobreira-Neto, Manoel Alves / Braga-Neto, Pedro

    Dementia & neuropsychologia

    2022  Volume 16, Issue 2, Page(s) 153–161

    Abstract: The prevalence of Parkinson's disease (PD) tends to increase worldwide in the coming decades. Thus, the incidence of falls is likely to increase, with a relevant burden on the health care system.: Objective: The objective of this study was to evaluate ...

    Abstract The prevalence of Parkinson's disease (PD) tends to increase worldwide in the coming decades. Thus, the incidence of falls is likely to increase, with a relevant burden on the health care system.
    Objective: The objective of this study was to evaluate clinical factors and drug use associated with falls in PD patients.
    Methods: We conducted a cross-sectional study at the Movement Disorders outpatient clinic of a tertiary hospital in Northeast Brazil. We performed structured interviews to collect sociodemographic and clinical data. Functional capacity was assessed using the Schwab and England Activities of Daily Living Scale and the modified Hoehn and Yahr Staging Scale. We divided the study sample into non-fallers (no falls) and fallers (≥1 fall), and non-recurrent (≤1 fall) and recurrent fallers (>1 fall).
    Results: The study population comprised 327 PD patients (48% women), with a mean age of 70 years. The mean disease duration was 9.9±6.9 years. The most prevalent comorbidities were depression (47.2%), hypertension (44.0%), and type 2
    Conclusions: Health care providers play an essential role in fall prevention in PD patients, particularly by identifying older adults experiencing dyskinesia and visual hallucinations. Prospective studies should investigate the use of amantadine as a risk factor for falls in PD patients.
    Language English
    Publishing date 2022-04-29
    Publishing country Brazil
    Document type Journal Article
    ISSN 1980-5764
    ISSN 1980-5764
    DOI 10.1590/1980-5764-DN-2021-0019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Cognitive Assessment Tools for Screening Older Adults With Low Levels of Education: A Critical Review.

    Tavares-Júnior, José Wagner Leonel / de Souza, Ana Célia Caetano / Alves, Gilberto Sousa / Bonfadini, Janine de Carvalho / Siqueira-Neto, José Ibiapina / Braga-Neto, Pedro

    Frontiers in psychiatry

    2019  Volume 10, Page(s) 878

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2019-12-13
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2019.00878
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Clinical correlates of sarcopenia and falls in Parkinson's disease.

    Lima, Danielle Pessoa / de Almeida, Samuel Brito / Bonfadini, Janine de Carvalho / de Luna, João Rafael Gomes / de Alencar, Madeleine Sales / Pinheiro-Neto, Edilberto Barreira / Viana-Júnior, Antonio Brazil / Veras, Samuel Ranieri Oliveira / Sobreira-Neto, Manoel Alves / Roriz-Filho, Jarbas de Sá / Braga-Neto, Pedro

    PloS one

    2020  Volume 15, Issue 3, Page(s) e0227238

    Abstract: Background: Sarcopenia is a complex and multifactorial geriatric condition seen in several chronic degenerative diseases. This study aimed to screen for sarcopenia and fall risk in a sample of Parkinson's disease (PD) patients and to investigate ... ...

    Abstract Background: Sarcopenia is a complex and multifactorial geriatric condition seen in several chronic degenerative diseases. This study aimed to screen for sarcopenia and fall risk in a sample of Parkinson's disease (PD) patients and to investigate demographic and clinical factors associated.
    Methods: This is a cross-sectional study. We evaluated 218 PD patients at the Movement Disorders Clinic in Fortaleza, Brazil, and collected clinical data including experiencing falls in the six months prior to their medical visit. Probable sarcopenia diagnosis was confirmed by using a sarcopenia screening tool (SARC-F questionnaire) and the presence of low muscle strength.
    Results: One hundred and twenty-one patients (55.5%) were screened positive for sarcopenia using the SARC-F and 103 (47.4%) met the criteria for probable sarcopenia. Disease duration, modified Hoehn and Yahr stage, Schwab and England Activities of Daily Living Scale score, levodopa equivalent dose, probable sarcopenia and positive SARC-F screening were all associated with experiencing falls. Disease duration, lower quality of life and female gender were independently associated with sarcopenia. Experiencing falls was significantly more frequent among patients screened positive in the SARC-F compared to those screened negative.
    Conclusions: Sarcopenia and PD share common pathways and may affect each other's prognosis and patients' quality of life. Since sarcopenia is associated with lower quality of life and increased risk of falls, active case finding, diagnosis and proper management of sarcopenia in PD patients is essential.
    MeSH term(s) Accidental Falls/prevention & control ; Accidental Falls/statistics & numerical data ; Activities of Daily Living ; Aged ; Brazil/epidemiology ; Cross-Sectional Studies ; Female ; Geriatric Assessment/statistics & numerical data ; Hand Strength ; Humans ; Male ; Middle Aged ; Parkinson Disease/complications ; Prognosis ; Quality of Life ; Risk Factors ; Sarcopenia/diagnosis ; Sarcopenia/epidemiology ; Sarcopenia/etiology ; Sarcopenia/therapy ; Sex Factors ; Surveys and Questionnaires/statistics & numerical data
    Language English
    Publishing date 2020-03-19
    Publishing country United States
    Document type Journal Article
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0227238
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Effects of a power strength training using elastic resistance exercises on the motor and non-motor symptoms in patients with Parkinson's disease H&Y 1-3: study protocol for a randomised controlled trial (PARK-BAND Study).

    Lima, Danielle Pessoa / de Almeida, Samuel Brito / Bonfadini, Janine de Carvalho / Sobreira, Emmanuelle Silva Tavares / Damasceno, Patrícia Gomes / Viana Júnior, Antonio Brazil / de Alencar, Madeleine Sales / de Luna, João Rafael Gomes / Rodrigues, Pedro Gustavo Barros / Pereira, Isabelle de Sousa / Gadelha, André Luis de Castro / de Oliveira, Liliane Maria / Chaves, Érica Carneiro Barbosa / Carneiro, Vlademir Gomes / Monteiro, Rayane Rodrigues / Costa, Thatyara Almeida de Macedo / Helal, Lucas / Signorile, Joseph / Lima, Lidiane Andréa Oliveira /
    Sobreira-Neto, Manoel Alves / Braga-Neto, Pedro

    BMJ open

    2020  Volume 10, Issue 10, Page(s) e039941

    Abstract: Introduction: Parkinson's disease (PD) is the second most common neurodegenerative disorder in Brazil. Physical activity is a complementary intervention in managing inherent declines associated with the disease like strength, balance, gait, and ... ...

    Abstract Introduction: Parkinson's disease (PD) is the second most common neurodegenerative disorder in Brazil. Physical activity is a complementary intervention in managing inherent declines associated with the disease like strength, balance, gait, and functionality and benefit health-related outcomes. Here, we report the PARK-BAND Study protocol, which aims to investigate potential benefits of power training using elastic devices in participants with PD. Our intervention will be provided in patients with PD using elastic devices like elastic bands and tubes. Therefore, we used the term Park from Parkinson's disease and band from elastic bands.
    Methods and analysis: This randomised single-blind single-centre two-arm parallel, superiority trial will include 50 participants with PD attending the clinical setting. Those who meet the eligibility criteria and provide consent to participate will be randomised in a 1:1 ratio to either the exercise group, which will receive power training programme or the health education group, which will receive the education programme. Randomisation will be performed by permuted block randomisation with a block size of eight. Both groups will receive a 12-week intervention. The exercise group will have two sessions per week and the health education group will have one session per week. Changes from baseline in bradykinesia, as assessed by the Unified Parkinson's Disease Rating Scale motor examination subscore and physical functional performance, will be the primary outcomes. Secondary outcomes include other neurological, neurophysiological and physical variables, as well as the quality of life, depression, cognition, sleep quality and disturbances, assessed before and after interventions. We hypothesise that the exercise group will have greater improvement in primary and secondary outcomes than the health education group.
    Ethics and dissemination: The study is approved by the Research Ethics Committee of Hospital Universitário Walter Cantidio and all participants will provide their written informed consent (register number 91075318.1.0000.5045).Trial results will be disseminated via peer reviewed journal articles and conference presentations, reports for organisations involved with PD and for participants.
    Trial registration number: Registro Brasileiro de Ensaios Clínicos Registry (RBR-5w2sqt); Pre-results.
    MeSH term(s) Humans ; Parkinson Disease/therapy ; Quality of Life ; Randomized Controlled Trials as Topic ; Resistance Training ; Single-Blind Method
    Language English
    Publishing date 2020-10-12
    Publishing country England
    Document type Clinical Trial Protocol ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2020-039941
    Database MEDical Literature Analysis and Retrieval System OnLINE

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