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  1. Article ; Online: The effect of lesser mealworm protein on exercise-induced muscle damage in active older adults: a randomized controlled trial.

    Koopmans, Lotte / Spoelder, Marcia / Bongers, Coen C W G / Eijsvogels, Thijs M H / Hopman, Maria T E

    The journal of nutrition, health & aging

    2024  Volume 28, Issue 5, Page(s) 100204

    Abstract: Objectives: We compared the effect of 12 weeks lesser mealworm-based (Alphitobius diaperinus) protein supplementation to whey protein and placebo supplementation on Exercise-Induced Muscle Damage (EIMD) after long-distance walking in older adults.: ... ...

    Abstract Objectives: We compared the effect of 12 weeks lesser mealworm-based (Alphitobius diaperinus) protein supplementation to whey protein and placebo supplementation on Exercise-Induced Muscle Damage (EIMD) after long-distance walking in older adults.
    Methods: in this randomized controlled trial, 70 physically active older adults (>60 years) were randomly allocated to the following groups: I) lesser mealworm protein, II) whey protein or III) iso-caloric placebo. Participants received supplements 11 weeks before and 1 week during a 3-day long-distance walking challenge (30-50 km per day). Blood concentrations of creatinine kinase (CK) and lactate dehydrogenase (LDH), handgrip strength and muscle soreness were measured pre-exercise and directly after each walking bout.
    Results: Significant elevations of CK concentrations (103 [76-161] U/l to 758 [342-1104] U/l, p < 0.001) and LDH concentrations (202 [175-220] to 283 [252-339] U/l, p < 0.001) were observed following 7h45 min ± 11 min of walking exercise per day, but the magnitude of this effect did not differ among suppletion groups. Hand grip strength decreased significantly (p < 0.001) while muscle soreness increased (p = 0.002) after the first walking day compared to pre-exercise, with no group differences.
    Conclusion: 12-weeks of lesser mealworm-based protein supplementation (30 g/day) does not attenuate exercise induced muscle damage in older adults following three days of prolonged walking exercise in comparison to placebo or whey protein.
    Language English
    Publishing date 2024-03-08
    Publishing country France
    Document type Journal Article
    ZDB-ID 2081921-3
    ISSN 1760-4788 ; 1279-7707
    ISSN (online) 1760-4788
    ISSN 1279-7707
    DOI 10.1016/j.jnha.2024.100204
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Potential mechanisms underlying the effect of walking exercise on cancer-related fatigue in cancer survivors.

    Mast, Isa Hiske / Bongers, Coen C W G / Gootjes, Elske C / de Wilt, Johannes H W / Hopman, Maria T E / Buffart, Laurien M

    Journal of cancer survivorship : research and practice

    2024  

    Abstract: Purpose: Cancer-related fatigue (CRF) is a common and debilitating long-term side effect of cancer and its treatment. While exercise has been shown to effectively reduce CRF, the underlying mechanisms are not fully clear. Therefore, the aim of this ... ...

    Abstract Purpose: Cancer-related fatigue (CRF) is a common and debilitating long-term side effect of cancer and its treatment. While exercise has been shown to effectively reduce CRF, the underlying mechanisms are not fully clear. Therefore, the aim of this study was to explore the effects of a 4-month walking exercise program on fatigue severity and to explore potential underlying physiological, behavioral, and psychological mechanisms of action.
    Methods: We included 27 cancer survivors (59 ± 15 years, 37% female) with variable cancer diagnoses who were at least moderately fatigued and finished treatment between 6 and 36 months ago. This study with a quasi-experimental interrupted time-series design compared a 4-month walking intervention period with a 4-month control period. Measurements of fatigue and physiological, behavioral, and psychological factors were performed, supplemented with participants' perceptions on how exercise influenced their fatigue.
    Results: A significant and clinically relevant decrease in fatigue severity was found over time (β =  - 8.1, 95% CI =  - 12.1; - 4.2), but could not be attributed directly to the walking exercise intervention. Increases in muscle strength (β =  - 0.07, 95% CI =  - 0.12; - 0.02), physical activity (β =  - 0.1, 95% CI =  - 0.2; - 0.04), and sleep quality (β = 1.1, 95% CI = 0.3; 1.9), as well as decreases in muscle relaxation times (β = 0.09, 95% CI = 0.02; 0.16) and psychological distress (β = 1.1, 95% CI = 0.8; 1.3) were associated with reductions in fatigue severity. Resilience and physical well-being were perceived as most important constructs explaining the walking exercise effects on fatigue.
    Conclusion: Our findings reveal potential physiological, behavioral, and psychological mechanisms underlying the multidimensional effects of exercise on fatigue severity.
    Implications for cancer survivors: Incorporating resistance exercise and addressing resilience and physical well-being might improve the efficacy of exercise interventions for cancer survivors.
    Language English
    Publishing date 2024-01-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2388888-X
    ISSN 1932-2267 ; 1932-2259
    ISSN (online) 1932-2267
    ISSN 1932-2259
    DOI 10.1007/s11764-024-01537-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Thermoregulatory, Cardiovascular and Perceptual Responses of Spectators of a Simulated Football Match in Hot and Humid Environmental Conditions.

    de Korte, Johannus Q / Eijsvogels, Thijs M H / Hopman, Maria T E / Bongers, Coen C W G

    Sports (Basel, Switzerland)

    2023  Volume 11, Issue 4

    Abstract: Major sporting events are often scheduled in thermally challenging environments. The heat stress may impact athletes but also spectators. We examined the thermal, cardiovascular, and perceptual responses of spectators watching a football match in a ... ...

    Abstract Major sporting events are often scheduled in thermally challenging environments. The heat stress may impact athletes but also spectators. We examined the thermal, cardiovascular, and perceptual responses of spectators watching a football match in a simulated hot and humid environment. A total of 48 participants (43 ± 9 years;
    Language English
    Publishing date 2023-03-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704239-X
    ISSN 2075-4663 ; 2075-4663
    ISSN (online) 2075-4663
    ISSN 2075-4663
    DOI 10.3390/sports11040078
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  4. Article ; Online: Performance Benefits of Pre- and Per-cooling on Self-paced Versus Constant Workload Exercise: A Systematic Review and Meta-analysis.

    van de Kerkhof, Tessa M / Bongers, Coen C W G / Périard, Julien D / Eijsvogels, Thijs M H

    Sports medicine (Auckland, N.Z.)

    2023  Volume 54, Issue 2, Page(s) 447–471

    Abstract: Background and objective: Exercise in hot environments impairs endurance performance. Cooling interventions can attenuate the impact of heat stress on performance, but the influence of an exercise protocol on the magnitude of performance benefit remains ...

    Abstract Background and objective: Exercise in hot environments impairs endurance performance. Cooling interventions can attenuate the impact of heat stress on performance, but the influence of an exercise protocol on the magnitude of performance benefit remains unknown. This meta-analytical review compared the effects of pre- and per-cooling interventions on performance during self-paced and constant workload exercise in the heat.
    Methods: The study protocol was preregistered at the Open Science Framework ( https://osf.io/wqjb3 ). A systematic literature search was performed in PubMed, Web of Science, and MEDLINE from inception to 9 June, 2023. We included studies that examined the effects of pre- or per-cooling on exercise performance in male individuals under heat stress (> 30 °C) during self-paced or constant workload exercise in cross-over design studies. Risk of bias was assessed using the Cochrane Risk of Bias Tool for randomized trials.
    Results: Fifty-nine studies (n = 563 athletes) were identified from 3300 records, of which 40 (n = 370 athletes) used a self-paced protocol and 19 (n = 193 athletes) used a constant workload protocol. Eighteen studies compared multiple cooling interventions and were included more than once (total n = 86 experiments and n = 832 paired measurements). Sixty-seven experiments used a pre-cooling intervention and 19 used a per-cooling intervention. Average ambient conditions were 34.0 °C [32.3-35.0 °C] and 50.0% [40.0-55.3%] relative humidity. Cooling interventions attenuated the performance decline in hot conditions and were more effective during a constant workload (effect size [ES] = 0.62, 95% confidence interval [CI] 0.44-0.81) compared with self-paced exercise (ES = 0.30, 95% CI 0.18-0.42, p = 0.004). A difference in performance outcomes between protocols was only observed with pre-cooling (ES = 0.74, 95% CI 0.50-0.98 vs ES = 0.29, 95% CI 0.17-0.42, p = 0.001), but not per-cooling (ES = 0.45, 95% CI 0.16-0.74 vs ES = 0.35, 95% CI 0.01-0.70, p = 0.68).
    Conclusions: Cooling interventions attenuated the decline in performance during exercise in the heat, but the magnitude of the effect is dependent on exercise protocol (self-paced vs constant workload) and cooling type (pre- vs per-cooling). Pre-cooling appears to be more effective in attenuating the decline in exercise performance during a constant workload compared with self-paced exercise protocols, whereas no differences were found in the effectiveness of per-cooling.
    MeSH term(s) Humans ; Male ; Workload ; Hot Temperature ; Exercise ; Cold Temperature ; Athletes
    Language English
    Publishing date 2023-10-06
    Publishing country New Zealand
    Document type Meta-Analysis ; Systematic Review
    ZDB-ID 605911-9
    ISSN 1179-2035 ; 0112-1642
    ISSN (online) 1179-2035
    ISSN 0112-1642
    DOI 10.1007/s40279-023-01940-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The contribution of physical exertion to heat-related illness and death in the Arizona borderlands.

    Chambers, Samuel N / Boyce, Geoffrey A / Martínez, Daniel E / Bongers, Coen C W G / Keith, Ladd

    Spatial and spatio-temporal epidemiology

    2023  Volume 46, Page(s) 100590

    Abstract: Recent studies and reports suggest an increased mortality rate of undocumented border crossers (UBCs) in Arizona is the result of heat extremes and climatic change. Conversely, others have shown that deaths have occurred in cooler environments than in ... ...

    Abstract Recent studies and reports suggest an increased mortality rate of undocumented border crossers (UBCs) in Arizona is the result of heat extremes and climatic change. Conversely, others have shown that deaths have occurred in cooler environments than in previous years. We hypothesized that human locomotion plays a greater role in heat-related mortality and that such events are not simply the result of exposure. To test our hypothesis, we used a postmortem geographic application of the human heat balance equation for 2,746 UBC deaths between 1990 and 2022 and performed regression and cluster analyses to assess the impacts of ambient temperature and exertion. Results demonstrate exertion having greater explaining power, suggesting that heat-related mortality among UBCs is not simply a function of extreme temperatures, but more so a result of the required physical exertion. Additionally, the power of these variables is not static but changes with place, time, and policy.
    MeSH term(s) Humans ; Arizona/epidemiology ; Hot Temperature ; Physical Exertion ; Climate Change ; Cluster Analysis
    Language English
    Publishing date 2023-06-01
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2515896-X
    ISSN 1877-5853 ; 1877-5845
    ISSN (online) 1877-5853
    ISSN 1877-5845
    DOI 10.1016/j.sste.2023.100590
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The effects of physical exercise on the assessment of kidney function.

    Beunders, Remi / Bongers, Coen C W G / Pickkers, Peter

    Journal of applied physiology (Bethesda, Md. : 1985)

    2020  Volume 128, Issue 5, Page(s) 1459–1460

    MeSH term(s) Acute Kidney Injury ; Creatinine ; Dehydration ; Exercise ; Hot Temperature ; Humans ; Hyperthermia ; Kidney ; Work
    Chemical Substances Creatinine (AYI8EX34EU)
    Language English
    Publishing date 2020-05-14
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 219139-8
    ISSN 1522-1601 ; 0021-8987 ; 0161-7567 ; 8750-7587
    ISSN (online) 1522-1601
    ISSN 0021-8987 ; 0161-7567 ; 8750-7587
    DOI 10.1152/japplphysiol.00189.2020
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  7. Article ; Online: Reply to Chapman et al.

    Beunders, Remi / Bongers, Coen C W G / Pickkers, Peter

    Journal of applied physiology (Bethesda, Md. : 1985)

    2020  Volume 129, Issue 1, Page(s) 162

    MeSH term(s) Acute Kidney Injury ; Dehydration ; Glomerular Filtration Rate ; Hot Temperature ; Humans ; Hyperthermia
    Language English
    Publishing date 2020-07-24
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 219139-8
    ISSN 1522-1601 ; 0021-8987 ; 0161-7567 ; 8750-7587
    ISSN (online) 1522-1601
    ISSN 0021-8987 ; 0161-7567 ; 8750-7587
    DOI 10.1152/japplphysiol.00464.2020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Beat the heat: How to become a gold medalist at the Tokyo Olympics.

    Eijsvogels, Thijs M H / de Korte, Johannus Q / Bongers, Coen C W G

    Temperature (Austin, Tex.)

    2021  Volume 8, Issue 3, Page(s) 203–205

    Language English
    Publishing date 2021-08-19
    Publishing country United States
    Document type Editorial
    ISSN 2332-8940
    ISSN 2332-8940
    DOI 10.1080/23328940.2021.1944005
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  9. Article ; Online: Impact of a COVID-19 infection on exercise levels of recreational athletes one- and three-months post-infection.

    Bongers, Coen C W G / Bakker, Esmée A / Buffart, Laurien M / Hopman, Maria T E

    Journal of sports sciences

    2022  , Page(s) 1–7

    Abstract: We examined the effect of a COVID-19 infection on changes in exercise levels in recreational athletes in the first three months after infection, and identified personal factors associated with a larger change in exercise level and recovery time. ... ...

    Abstract We examined the effect of a COVID-19 infection on changes in exercise levels in recreational athletes in the first three months after infection, and identified personal factors associated with a larger change in exercise level and recovery time. Recreational athletes (n=4360) completed an online questionnaire on health and exercise levels. 601 Athletes have had a diagnostically confirmed COVID-19 infection, while 3479 athletes did not (non-COVID-19 group). Exercise levels (in MET-min/week) were examined prior to (2019) and during the COVID-19 pandemic (2020) for the non-COVID-19 group, and in 2019, 1-month pre-COVID-19 infection, 1-month post-COVID-19 infection and 3 months post-COVID-19 infection in the COVID-19 group. Median exercise level at baseline in the COVID-19 group was 3528 (IQR=1488-5760) MET-min/week. One-month post-COVID-19 infection, exercise level dropped 58% (2038 MET-min/week), which partly stabilized to 36% (1256 MET-min/week) below baseline values 3 months post-COVID-19 infection. Moreover, in both the COVID-19 (pre-COVID-19 infection) and non-COVID-19 group exercise levels during the pandemic decreased with ~260 MET-min/week. These results illustrate that even a relatively physically active population of recreational athletes is significantly affected by a COVID-19 infection, particularly those athletes who are overweight. COVID-19 disease burden, age, sex, comorbidities and smoking were not associated with reduced exercise levels.
    Language English
    Publishing date 2022-10-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 995528-8
    ISSN 1466-447X ; 0264-0414
    ISSN (online) 1466-447X
    ISSN 0264-0414
    DOI 10.1080/02640414.2022.2140919
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Supplementation with Whey Protein, but Not Pea Protein, Reduces Muscle Damage Following Long-Distance Walking in Older Adults.

    Spoelder, Marcia / Koopmans, Lotte / Hartman, Yvonne A W / Bongers, Coen C W G / Schoofs, Merle C A / Eijsvogels, Thijs M H / Hopman, Maria T E

    Nutrients

    2023  Volume 15, Issue 2

    Abstract: Background: Adequate animal-based protein intake can attenuate exercise induced-muscle damage (EIMD) in young adults. We examined the effects of 13 days plant-based (pea) protein supplementation compared to whey protein and placebo on EIMD in active ... ...

    Abstract Background: Adequate animal-based protein intake can attenuate exercise induced-muscle damage (EIMD) in young adults. We examined the effects of 13 days plant-based (pea) protein supplementation compared to whey protein and placebo on EIMD in active older adults. Methods: 47 Physically active older adults (60+ years) were randomly allocated to the following groups: (I) whey protein (25 g/day), (II) pea protein (25 g/day) or (III) iso-caloric placebo. Blood concentrations of creatine kinase (CK) and lactate dehydrogenase (LDH), and skeletal muscle mass, muscle strength and muscle soreness were measured prior to and 24 h, 48 h and 72 h after a long-distance walking bout (20−30 km). Results: Participants walked 20−30 km and 2 dropped out, leaving n = 15 per subgroup. The whey group showed a significant attenuation of the increase in EIMD at 24 h post-exercise compared to the pea and placebo group (CK concentration: 175 ± 90 versus 300 ± 309 versus 330 ± 165, p = p < 0.001). No differences in LDH levels, muscle strength, skeletal muscle mass and muscle soreness were observed across groups (all p-values > 0.05). Conclusions: Thirteen days of pea protein supplementation (25 g/day) does not attenuate EIMD in older adults following a single bout of prolonged walking exercise, whereas the whey protein supplementation group showed significantly lower post-exercise CK concentrations.
    MeSH term(s) Middle Aged ; Creatine Kinase ; Dietary Supplements ; Muscle, Skeletal/metabolism ; Myalgia/prevention & control ; Walking ; Whey Proteins/administration & dosage ; Humans ; Pisum sativum ; Plant Proteins/administration & dosage
    Chemical Substances Creatine Kinase (EC 2.7.3.2) ; Whey Proteins ; Plant Proteins
    Language English
    Publishing date 2023-01-10
    Publishing country Switzerland
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15020342
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