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  1. Article: Parascapular Flap for Severe Hidradenitis Suppurativa.

    Khayat, Saad / Bonsfills, Nuria / Antúnez-Conde, Raúl / Álvarez-Mokthari, Sara / Aranibar, Hubert / Tousidonis, Manuel / Fernández-Fernández, Mario / Díez-Montiel, Alberto

    Case reports in dermatology

    2024  Volume 16, Issue 1, Page(s) 8–16

    Abstract: Hidradenitis suppurativa is a chronic inflammatory disease which affects apocrine glands and hair follicles of the skin, primarily in the axillary and groin regions. This condition can be highly debilitating, causing painful lesions and a negative ... ...

    Abstract Hidradenitis suppurativa is a chronic inflammatory disease which affects apocrine glands and hair follicles of the skin, primarily in the axillary and groin regions. This condition can be highly debilitating, causing painful lesions and a negative psychological impact on patients. While medical and minimally invasive treatments are available, surgical intervention may be necessary for severe cases. In cases involving axillary defects, the use of local flaps such as the parascapular flap is a viable option. In this case report, we present a 34-year-old woman who presented to our clinic with a history of recurrent abscesses and cutaneous infections in the axillary region. After thorough evaluation, we chose to use the parascapular flap for reconstruction. The parascapular flap is a one-stage procedure that allows for extensive resection of the axillary area without resulting in contractions or retractions over the long term. Additionally, this technique allows for preservation of the axilla's original shape with minimal donor site morbidity.
    Language English
    Publishing date 2024-01-05
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2505300-0
    ISSN 1662-6567
    ISSN 1662-6567
    DOI 10.1159/000533387
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Embryonal Rhabdomyosarcoma of the Tongue in Adults.

    Díez-Montiel, Alberto / Antúnez-Conde, Raúl / Navarro Cuéllar, Carlos / Tousidonis Rial, Manuel / Salmerón, José Ignacio / Bonsfills, Nuria / Pujol, Carolina Agra / Serrano, Francisco Alijo / Ochandiano, Santiago

    Life (Basel, Switzerland)

    2023  Volume 13, Issue 6

    Abstract: 1) Background: Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in the first two decades of life. One third of cases appear in the head and neck, with 60% of these being embryonal type. RMS is extremely rare in adults, comprising only 1% of ...

    Abstract (1) Background: Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in the first two decades of life. One third of cases appear in the head and neck, with 60% of these being embryonal type. RMS is extremely rare in adults, comprising only 1% of adult malignancies, and of those, only 3.3% are rhabdomyosarcomas. (2) Case report: A 46 y.o. male presented with a 1 cm exophytic pediculated painless lesion on the dorsum of his tongue, with progressive growth for 3 months. An excisional biopsy revealed an "embryonal rhabdomyosarcoma with fusocellular areas, with negative rearrangement for gen FOXO1A, negative MDM2 (only focal positivity), and positive INI-1". Subsequent contrast-enhanced MRI concluded the presence of a lesion with imprecise margins in the right half-tongue, 15 × 8 × 7 mm (longitudinal × transverse × craniocaudal), compatible with a sarcoma. The patient underwent a partial centrolingual glossectomy followed by reconstruction with a buccinator muscle local flap. After surgery, he received chemotherapy with eight cycles of VAC (vincristine, actinomycin, and cyclophosphamide) protocol. The patient is now disease free after 42 months, with good tongue function. (3) Discussion and conclusions: Embryonal RMS is an extremely rare sarcoma in adults, and the location in the tongue is even more exceptional (only two more similar cases are reported in the literature). The prognosis in adults is significantly poorer than in children. A complete margin-free resection with an adequate chemotherapy protocol is the treatment of choice in cases such as these.
    Language English
    Publishing date 2023-05-25
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life13061255
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  3. Article ; Online: Periarticular muscle stimulation controls anterior tibial laxity after experimental ACL section: an experimental study.

    Bonsfills, Nuria / Nuñez, Angel / Gomez-Barrena, Enrique

    Archives of orthopaedic and trauma surgery

    2009  Volume 129, Issue 8, Page(s) 1053–1061

    Abstract: Background and purpose: Besides current strategies to treat potentially disabling anterior cruciate ligament (ACL) injury, a new and innovative approach was designed based on electrical stimulation of the muscle to prevent unwanted displacement of the ... ...

    Abstract Background and purpose: Besides current strategies to treat potentially disabling anterior cruciate ligament (ACL) injury, a new and innovative approach was designed based on electrical stimulation of the muscle to prevent unwanted displacement of the tibia relative to the femur. Our aim was to measure muscular strain and anterior tibial translation (ATT) in a controlled study using an animal model of ACL-deficient knee undergoing muscular electric stimulation.
    Methods: Seventeen cat knees under tibial anterior traction of 24.5 N were studied before and after ACL transection. Muscular fiber length variation was obtained by ultrasonomicrometry and ATT by video recordings at the beginning, during, and at the end of the movement. Square pulses of 0.2 ms with 5 V were applied in trains of 500, 100, and 20 ms simultaneously to both the quadriceps and hamstrings before and immediately after traction.
    Results: Electric stimulation of ACL-deficient knees normalized muscular strain to values of control knees. An increased resistance to muscular lengthening was observed in stimulated knees. Stimulation before traction maintained similar ATT than control knees during the subsequent traction.
    Discussion: Electric muscular stimulation in the ACL-deficient knee provoked periarticular muscle contraction, controlling ATT when time-adjusted stimulus (before traction) was used. This suggested that artificially inducing the muscular response could help to control anterior knee laxity after ACL injury.
    MeSH term(s) Animals ; Anterior Cruciate Ligament Injuries ; Cats ; Electric Stimulation Therapy ; Joint Instability/etiology ; Joint Instability/therapy ; Knee Injuries/complications ; Knee Joint ; Muscle Contraction ; Muscle, Skeletal ; Tibia
    Language English
    Publishing date 2009-08
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80407-1
    ISSN 1434-3916 ; 0003-9330 ; 0344-8444
    ISSN (online) 1434-3916
    ISSN 0003-9330 ; 0344-8444
    DOI 10.1007/s00402-008-0763-y
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  4. Article: Solitary epiphyseal enchondroma of the proximal femur in a 23-month-old girl.

    Ojeda-Thies, Cristina / Bonsfills, Nuria / Albiñana, Javier

    Journal of pediatric orthopedics

    2008  Volume 28, Issue 5, Page(s) 565–568

    Abstract: Unlabelled: A 23-month-old girl was referred to us because of a right leg limp for 10 days that had not improved despite anti-inflammatory treatment and that did not show signs of infection. Upon examination, gait was in abduction and external rotation ... ...

    Abstract Unlabelled: A 23-month-old girl was referred to us because of a right leg limp for 10 days that had not improved despite anti-inflammatory treatment and that did not show signs of infection. Upon examination, gait was in abduction and external rotation of the hip. Plain radiographs showed a solitary lucent lesion of the posteroinferior two thirds of the epiphysis that was hyperintense on T2-weighted magnetic resonance scanning images. We approached the proximal femoral epiphysis using the "trapdoor" technique and excised the lesion by curettage and iliac crest graft. Histologically, the lesion was diagnosed as an enchondroma. We discuss the main causes of lucent epiphyseal lesions in children. Finally, we review the literature on previous reports of patients with solitary epiphyseal enchondromas.
    Study type: Case report.
    MeSH term(s) Chondroma/diagnosis ; Chondroma/surgery ; Diagnostic Imaging ; Epiphyses/pathology ; Female ; Femoral Neoplasms/diagnosis ; Femoral Neoplasms/surgery ; Humans ; Infant
    Language English
    Publishing date 2008-07
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 604642-3
    ISSN 1539-2570 ; 0271-6798
    ISSN (online) 1539-2570
    ISSN 0271-6798
    DOI 10.1097/BPO.0b013e31817e2425
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    Zs.A 1681: Show issues Location:
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  5. Article: Bilateral anterior dislocation of the shoulder: review of seventy cases and proposal of a new etiological-mechanical classification.

    Ballesteros, Rafael / Benavente, Pablo / Bonsfills, Nuria / Chacón, Marta / García-Lázaro, Francisco J

    The Journal of emergency medicine

    2013  Volume 44, Issue 1, Page(s) 269–279

    Abstract: Background: Although anterior shoulder dislocation is common in everyday practice in Emergency Departments, bilateral presentation is a rare entity.: Objectives: The aim of this article is to report two additional cases of this rare injury and to ... ...

    Abstract Background: Although anterior shoulder dislocation is common in everyday practice in Emergency Departments, bilateral presentation is a rare entity.
    Objectives: The aim of this article is to report two additional cases of this rare injury and to introduce a new mechanism that can produce it. We made an exhaustive review of the literature and found 68 cases in printed publications. Also, we analyzed the mechanism of injury and the presence of predisposing factors, and propose a new etiological-mechanical classification.
    Case report: One case occurred after a trivial fall, and the other was produced by a mechanism not previously reported: the patient pushed strongly forward, expecting a resistance and finding none, his arms kept the forward movement and the shoulders dislocated.
    Discussion: This lesion has a bimodal distribution, affecting mainly men (70%) with a mean age of 33.5 years, whereas in women, the average age is 57 years. The most common cause is trauma (50%), followed by muscle contractions (37%) due to seizures of different causes (epileptic, hypoglycemia, toxic, or hypoxic) or electrocution. In 15.7% of the cases, the diagnosis of bilateral anterior dislocation was not acute (<3 weeks), and in virtually all of these cases it was not traumatic.
    Conclusion: The bilateral anterior shoulder dislocation may not be as rare as previously thought and must be taken into account in emergency services. The authors propose a new etiological-mechanical classification. Also, the importance of radiologic diagnosis must be highlighted.
    MeSH term(s) Adolescent ; Aged ; Female ; Humans ; Male ; Radiography ; Shoulder Dislocation/diagnostic imaging ; Shoulder Dislocation/etiology ; Shoulder Dislocation/pathology
    Language English
    Publishing date 2013-01
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 605559-x
    ISSN 0736-4679
    ISSN 0736-4679
    DOI 10.1016/j.jemermed.2012.07.047
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    Zs.A 1895: Show issues Location:
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  6. Article ; Online: Histomorphometry of the ligaments using a generic-purpose image processing software, a new strategy for semi-automatized measurements.

    Ballesteros, Rafael / Bonsfills, Nuria / Chacón, Marta / García-Lázaro, Javier / Gómez-Barrena, Enrique

    Journal of digital imaging

    2011  Volume 25, Issue 4, Page(s) 527–536

    Abstract: Gold chloride technique can be combined with Adobe Photoshop® software to yield a quantitative assessment of the different areas in heterogeneous structures as are ligament. A semi-automatized method based on the sum of two- and three-dimensional ... ...

    Abstract Gold chloride technique can be combined with Adobe Photoshop® software to yield a quantitative assessment of the different areas in heterogeneous structures as are ligament. A semi-automatized method based on the sum of two- and three-dimensional morphological criteria upon colorimetric criteria allows the identification and measurement of the area occupied by a structure of interest. It also allows the quantification of color intensity to differentiate structures with similar staining avidity, like vessels and nerves. This computer-assisted, semiquantitative procedure for computerized morphometry is relatively simple to perform. The accuracy, efficiency, and reproducibility of this method based on a commercially available imaging program were considered adequate when tested on the anterior cruciate ligament of the cat. Image normalization by trained observers using a commercially available software package designed for photography, applied to a sample randomly chosen, has provided the means of making reproducible measurements of heterogeneous structures.
    MeSH term(s) Animals ; Anterior Cruciate Ligament ; Cats ; Histological Techniques/methods ; Image Processing, Computer-Assisted/methods ; Observer Variation ; Photography/methods ; Reproducibility of Results ; Software ; Staining and Labeling/methods
    Language English
    Publishing date 2011-12-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1033897-4
    ISSN 1618-727X ; 0897-1889
    ISSN (online) 1618-727X
    ISSN 0897-1889
    DOI 10.1007/s10278-011-9440-8
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    Zs.A 2941: Show issues Location:
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  7. Article ; Online: Insufficient recovery of neuromuscular activity around the knee after experimental anterior cruciate ligament reconstruction.

    Gómez-Barrena, Enrique / Bonsfills, Nuria / Martín, José G / Ballesteros-Massó, Rafael / Foruria, Antonio / Núñez-Molina, Angel

    Acta orthopaedica

    2008  Volume 79, Issue 1, Page(s) 39–47

    Abstract: Background: Operative and nonoperative treatment of anterior cruciate ligament (ACL) injuries is often associated with a lack of proprioception and persistent muscle weakness of unknown origin.: Methods: This long-term study in the cat experimentally ...

    Abstract Background: Operative and nonoperative treatment of anterior cruciate ligament (ACL) injuries is often associated with a lack of proprioception and persistent muscle weakness of unknown origin.
    Methods: This long-term study in the cat experimentally compares both neural and muscular activity in the articular nerves of the knee (PAN and MAN), quadriceps and hamstrings, in the chronic unstable knee, and in the reconstructed knee. We also investigated changes in neuromuscular response due to the mechanical competence of the graft, comparing stable and unstable reconstructed knees.
    Results: We found increased periarticular muscle activity during anterior tibial translation in chronically unstable knees. Both reconstructed and non-reconstructed knees lost fast reactive activity in the articular nerves. When stability was recovered after reconstruction, the knees showed a more adjusted - although incomplete - muscular reaction.
    Interpretation: ACL-injured knees in the cat, with or without reconstruction, show definite abnormalities in neuromuscular reaction in the long term. Regaining stability with a competent graft in the reconstructed knee is crucial for reduction of this anomalous reaction.
    MeSH term(s) Animals ; Anterior Cruciate Ligament/surgery ; Anterior Cruciate Ligament Injuries ; Cats ; Humans ; Joint Instability/etiology ; Joint Instability/prevention & control ; Knee Joint/innervation ; Knee Joint/physiology ; Muscle Strength/physiology ; Muscle, Skeletal/physiology ; Proprioception/physiology ; Quadriceps Muscle/physiology ; Reconstructive Surgical Procedures/methods ; Recovery of Function
    Language English
    Publishing date 2008-02
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2180677-9
    ISSN 1745-3682 ; 1745-3674
    ISSN (online) 1745-3682
    ISSN 1745-3674
    DOI 10.1080/17453670710014743
    Database MEDical Literature Analysis and Retrieval System OnLINE

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