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Article ; Online: The anatomy of the pectoral nerves and its significance in reconstruction and augmentation of the breast.

Riggio, Egidio / Bordoni, Daniele

Journal of plastic, reconstructive & aesthetic surgery : JPRAS

2013 Volume 66, Issue 6, Page(s) 870–871

MeSH term(s)	Axilla/surgery ; Brachial Plexus/anatomy & histology ; Female ; Humans ; Male ; Mammaplasty/methods ; Surgical Flaps ; Thoracic Nerves/anatomy & histology
Language	English
Publishing date	2013-06
Publishing country	Netherlands
Document type	Comment ; Letter
ZDB-ID	2217750-4
ISSN	1878-0539 ; 1748-6815 ; 0007-1226
ISSN (online)	1878-0539
ISSN	1748-6815 ; 0007-1226
DOI	10.1016/j.bjps.2012.11.041
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Article ; Online: Reconstruction of a large upper arm defect with muscle sparing latissimus dorsi.

Cadenelli, Pierfrancesco / Bordoni, Daniele / Ornelli, Matteo / Radaelli, Stefano

BMJ case reports

2016 Volume 2016

Abstract: Reconstruction of large soft tissue defects in the upper arm represents a challenge for the reconstructive surgeon. The latissimus dorsi flap is widely used and preferred for this latter type of reconstruction due to its reliability and versatility, ... ...

Abstract	Reconstruction of large soft tissue defects in the upper arm represents a challenge for the reconstructive surgeon. The latissimus dorsi flap is widely used and preferred for this latter type of reconstruction due to its reliability and versatility, although sacrificing the entire muscle can lead to higher incidences of postoperative seroma and functional disability. The recent introduction of the perforator-based flap concept has led to an evolution in upper extremity reconstruction by significantly reducing donor-site morbidity and simultaneously ensuring optimal soft tissues coverage. We report a case of a large soft tissue defect of the posterolateral part of the upper arm, consequent to a sarcoma resection, in which a muscle-sparing latissimus dorsi technique was used to obtain total soft tissue coverage. A 2-year follow-up showed a satisfactory functional result and no evidence of recurrence.
MeSH term(s)	Aged ; Arm/surgery ; Humans ; Male ; Reconstructive Surgical Procedures/methods ; Sarcoma/surgery ; Soft Tissue Neoplasms/surgery ; Superficial Back Muscles/transplantation ; Surgical Flaps ; Treatment Outcome
Language	English
Publishing date	2016-08-23
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1757-790X
ISSN (online)	1757-790X
DOI	10.1136/bcr-2016-216684
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Article ; Online: Proximally Based Anterolateral-Thigh (ALT) Flap for Knee Reconstruction: An Advancement Propeller Perforator Flap.

Cadenelli, Pierfrancesco / Bordoni, Daniele / Radaelli, Stefano / Marchesi, Andrea

Aesthetic plastic surgery

2015 Volume 39, Issue 5, Page(s) 752–756

Abstract: Background: Adequate coverage of the knee region is often challenging for plastic and orthopedic surgeons. In the last decade, among several reconstructive techniques, local perforator flaps have become useful reconstructive units. After a wide ... ...

Abstract	Background: Adequate coverage of the knee region is often challenging for plastic and orthopedic surgeons. In the last decade, among several reconstructive techniques, local perforator flaps have become useful reconstructive units. After a wide resection for soft-tissue sarcoma, the knee vascular web may be reasonably damaged and, consequently, perforator flaps based on a local pedicle [such as the distally based anterolateral thigh (ALT) flap] are not reliable. Thus, we harvested a proximally based ALT for knee coverage. Methods: A 52-year-old man underwent local radiation therapy and a wide resection of a soft-tissue sarcoma on the anterior-lateral aspect of the left knee, which resulted in a 15 × 10 cm defect. The defect was covered with a proximally based ALT, through an advancement and propeller relocation of its skin paddle. Results: All margins were tumor free. After 5 days, the donor site was closed primarily because of edema. Neither necrosis of the flap nor dehiscence of the wound was detected. No local relapses were detected at 6-month follow-up. Conclusions: In case of soft-tissue defects of the knee region, with likely involvement of the local vascular web, a local perforator solution is the advancement and propeller proximally based ALT flap. Level of evidence v: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
MeSH term(s)	Humans ; Knee ; Male ; Middle Aged ; Myocutaneous Flap/blood supply ; Myocutaneous Flap/transplantation ; Perforator Flap/blood supply ; Perforator Flap/transplantation ; Reconstructive Surgical Procedures/methods ; Recovery of Function ; Risk Assessment ; Sarcoma/pathology ; Sarcoma/surgery ; Skin Neoplasms/pathology ; Skin Neoplasms/surgery ; Thigh/surgery ; Tissue and Organ Harvesting ; Treatment Outcome ; Wound Healing/physiology
Language	English
Publishing date	2015-10
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	532791-x
ISSN	1432-5241 ; 0364-216X
ISSN (online)	1432-5241
ISSN	0364-216X
DOI	10.1007/s00266-015-0536-2
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Article ; Online: Oncologic surveillance of breast cancer patients after lipofilling.

Riggio, Egidio / Bordoni, Daniele / Nava, Maurizio B

Aesthetic plastic surgery

2013 Volume 37, Issue 4, Page(s) 728–735

Abstract: Background: The regenerative effects of fat injections are based on the same hormones, growth factors, and stem cells that stimulate neoplastic angiogenesis and cancer progression in basic research. Few studies have analyzed the oncologic risk. No ... ...

Abstract	Background: The regenerative effects of fat injections are based on the same hormones, growth factors, and stem cells that stimulate neoplastic angiogenesis and cancer progression in basic research. Few studies have analyzed the oncologic risk. No report has covered 5 years of oncologic surveillance, and no long-term risk has been estimated. The in vivo relationship between lipofilling and breast cancer remains unclear and controversial. This observational study focused on locoregional recurrence (LR) risk after lipofilling. Methods: The study enrolled 60 patients after breast cancer surgery (total mastectomy) from 2000 to 2007 treated by lipofilling (82 single-surgeon procedures with the same fat-decanting technique). The study ended when follow-up observation reached 10 years. Results: The study included invasive carcinoma (55 cases), in situ carcinoma (five cases), T1 (71.6 %) and T2 (23.3 %) carcinoma, N+ carcinoma (45 %), and stages 1 (43.3 %) and 2 (45 %) carcinoma. The overall 12-year incidence of LR was 5 % (1.6 % before and 3.3 % after lipofilling). The incidence of local relapse per 100 person-years was 0.36 in the first observation period and 0.43 after lipofilling. All LRs were stage 2, and the same rate, limited to stage 2, was 1.04. The crude cumulative incidence after lipofilling was 7.25 % (95 % confidence interval [CI], 0-15.4 %) for LR and 7.6 % (95 % CI, 0.2-15 %) for distant metastases. Discussion: Clinical data and recurrence incidences were compared with those of prior publications concerning lipofilling oncologic risk and discussed in relation to the inherent cancer literature. Conclusions: Lipofilling may be used safely to treat tumor node metastasis stage 1 subjects after mastectomy. The local risk is low. For stage 2 patients, local failure was not significantly higher. Compared with institutional data and prior publications, the risk still is reliable. Breast conservative treatment must be investigated further because of the high risk for local relapse. Level of evidence iii: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
MeSH term(s)	Adult ; Aged ; Breast Neoplasms/pathology ; Breast Neoplasms/surgery ; Carcinoma, Ductal, Breast/surgery ; Carcinoma, Intraductal, Noninfiltrating/surgery ; Continuity of Patient Care ; Female ; Humans ; Mammaplasty/methods ; Mastectomy ; Middle Aged ; Neoplasm Recurrence, Local/epidemiology ; Neoplasm Recurrence, Local/prevention & control ; Subcutaneous Fat, Abdominal/transplantation
Language	English
Publishing date	2013-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	532791-x
ISSN	1432-5241 ; 0364-216X
ISSN (online)	1432-5241
ISSN	0364-216X
DOI	10.1007/s00266-013-0166-5
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Article ; Online: The axillary flap in oncoplastic resection of breast cancers located in the upper-outer quadrants: a new surgical technique.

Bordoni, Daniele / Cadenelli, Pierfrancesco / Ornelli, Matteo / Falco, Giuseppe / Accurso, Antonello / Gloria, Antonio / Maietta, Saverio / Rocco, Nicola / Magalotti, Cesare

BMC surgery

2019 Volume 18, Issue Suppl 1, Page(s) 21

Abstract: Background: The combination of breast conserving surgery (BCS) with plastic surgery techniques has provided a useful surgical tool matching the radicality of the oncological excision with the preservation of breast cosmesis. Even though BCS represents a ...

Abstract	Background: The combination of breast conserving surgery (BCS) with plastic surgery techniques has provided a useful surgical tool matching the radicality of the oncological excision with the preservation of breast cosmesis. Even though BCS represents a good option for surgical treatment of tumors located in these quadrants, wide excisions often necessitate breast reshaping in order to avoid nipple areola complex (NAC) displacement and skin retraction. We present a new surgical technique to repair upper-outer quadrants' defects following breast cancer excision using dermo-glandular flaps and an axillary adipo-fascial flap. Methods: During the period from January 2014 to December 2015, 168 patients with an upper-outer quadrant's breast cancer have been treated in our Department. 83 women have been treated with the described oncoplastic technique and immediate contra-lateral symmetrisation and 85 women underwent standard BCS. We present surgical, oncological and cosmetic outcomes comparing our results with standard BCS. Results: At a mean follow-up of 27 months loco-regional recurrences in the two groups were comparable. Short-term complication rates were comparable between the two groups. Re-intervention rates for positive margins were significantly higher in the standard BCS group. The overall satisfaction with cosmetic outcome both assessed by the patient and the surgeon was significantly higher in the oncoplastic group. Conclusions: The proposed oncoplastic technique represents a safe and effective solution for reshaping that follows upper-outer breast cancer wide excision, achieving comparable complication rates, lower re-intervention rates for positive margins and better cosmetic results when compared with standard BCS.
MeSH term(s)	Adult ; Aged ; Axilla ; Breast Neoplasms/surgery ; Female ; Humans ; Mammaplasty/methods ; Margins of Excision ; Mastectomy, Segmental/methods ; Middle Aged ; Neoplasm Recurrence, Local/surgery ; Retrospective Studies ; Surgical Flaps
Language	English
Publishing date	2019-04-24
Publishing country	England
Document type	Journal Article
ZDB-ID	2050442-1
ISSN	1471-2482 ; 1471-2482
ISSN (online)	1471-2482
ISSN	1471-2482
DOI	10.1186/s12893-018-0467-3
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Article: Cutaneous basal cell carcinoma arising within a keloid scar: a case report.

Goder, Maya / Kornhaber, Rachel / Bordoni, Daniele / Winkler, Eyal / Haik, Josef / Tessone, Ariel

OncoTargets and therapy

2016 Volume 9, Page(s) 4793–4796

Abstract: Basal cell carcinomas (BCCs) are one of the most frequent cutaneous malignancies. The majority of BCCs are reported to occur on the auricular helix and periauricular region due to ultraviolet light exposure. Despite the frequency of BCCs, those that ... ...

Abstract	Basal cell carcinomas (BCCs) are one of the most frequent cutaneous malignancies. The majority of BCCs are reported to occur on the auricular helix and periauricular region due to ultraviolet light exposure. Despite the frequency of BCCs, those that develop within scar tissue are rare, and the phenomenon of keloid BCCs has rarely been reported in the literature. Keloid collagen within BCCs is associated with morphoeiform characteristics, ulceration, or necrosis. Extensive keloid collagen is often seen in BCCs of the ear region, a site prone to keloid scarring. This article presents a rare case of a secondary tumor (BCC) which arose on top of a primary tumor (keloid scar) on the right auricle region in a healthy 23-year-old female after an ear piercing 2 years prior. To our knowledge, the tumor described in this case, in contrast to keloidal BCCs, has never been reported in the literature.
Language	English
Publishing date	2016-08-02
Publishing country	New Zealand
Document type	Case Reports
ZDB-ID	2495130-4
ISSN	1178-6930
ISSN	1178-6930
DOI	10.2147/OTT.S113724
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Article ; Online: Serratus Anterior Fascia Flap Versus Muscular Flap for Expander Coverage in Two-stage Breast Reconstruction Following Mastectomy: Early Post-operative Outcomes.

Bordoni, Daniele / Cadenelli, Pierfrancesco / Rocco, Nicola / Tessone, Ariel / Falco, Giuseppe / Magalotti, Cesare

Aesthetic plastic surgery

2016 Volume 41, Issue 1, Page(s) 26–30

Abstract: Introduction: The demand for reconstructive breast surgery after mastectomy is increasing among women and the two-stage option remains the most commonly performed technique. We conducted a self-controlled prospective clinical trial comparing the use of ... ...

Abstract	Introduction: The demand for reconstructive breast surgery after mastectomy is increasing among women and the two-stage option remains the most commonly performed technique. We conducted a self-controlled prospective clinical trial comparing the use of the serratus anterior fascia with the serratus anterior detached fibers to cover the inferolateral aspect of the expander in immediate two-stage breast reconstruction following conservative mastectomies as oncological or risk-reducing procedures. Patients and methods: We analyzed the surgical outcome of 29 bilateral mastectomies and immediate reconstruction with the positioning of a tissue expander in a pocket beneath the pectoralis major and serratus anterior muscle on one side and in a pocket beneath the pectoralis major and a serratus anterior fascia flap on the other side. We considered all complications presenting in the first month after surgery and patient-reported early post-operative pain. Results: Complication rates in the two groups did not significantly differ (p = 0.237). The total amount of drainage and the time of drainage permanence were significantly lower for the subfascial group (p < 0.05). Patient-reported early post-operative pain was significantly different between the two groups both at 24 h (p < 0.05) and at 5 days (p < 0.05) with significantly lower pain scores reported by the patients in the subfascial group. Discussion: Our self-controlled prospective trial demonstrated an advantage in performing an implant-based two-stage breast reconstruction using a serratus anterior fascia flap when compared with the serratus muscle fibers use for inferolateral implant coverage following mastectomy. The use of the anterior serratus fascia flap for inferolateral implant coverage in two-stage breast reconstructions following mastectomy could be considered as a safe and effective technique, presenting lower morbidity for the patient when compared with the serratus muscle fibers use and lower costs when compared with biological and synthetic meshes use, achieving good outcomes in terms of post-operative complications and women's quality of life and satisfaction levels. Level of evidence iii: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
MeSH term(s)	Adult ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Breast Neoplasms/surgery ; Cohort Studies ; Esthetics ; Fascia/blood supply ; Fascia/transplantation ; Female ; Graft Rejection ; Graft Survival ; Humans ; Mammaplasty/adverse effects ; Mammaplasty/methods ; Mastectomy/methods ; Middle Aged ; Myocutaneous Flap/blood supply ; Myocutaneous Flap/transplantation ; Pain, Postoperative/physiopathology ; Patient Satisfaction/statistics & numerical data ; Postoperative Complications/epidemiology ; Postoperative Complications/physiopathology ; Postoperative Period ; Prospective Studies ; Risk Assessment ; Tissue Expansion/methods ; Wound Healing/physiology
Language	English
Publishing date	2016-12-28
Publishing country	United States
Document type	Comparative Study ; Evaluation Study ; Journal Article
ZDB-ID	532791-x
ISSN	1432-5241 ; 0364-216X
ISSN (online)	1432-5241
ISSN	0364-216X
DOI	10.1007/s00266-016-0770-2
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Article: Extreme oncoplastic breast surgery: A case report.

Bordoni, Daniele / Cadenelli, Pierfrancesco / Falco, Giuseppe / Rocco, Nicola / Manna, Paola / Tessone, Ariel / Ornelli, Matteo / Magalotti, Cesare

International journal of surgery case reports

2016 Volume 28, Page(s) 182–187

Abstract: Introduction: So called "extreme oncoplastic surgery" is emerging as a new promising concept in breast cancer surgery allowing successful breast conservation in selected patients with multicentric tumors.: Presentation of case: We report the case of ... ...

Abstract	Introduction: So called "extreme oncoplastic surgery" is emerging as a new promising concept in breast cancer surgery allowing successful breast conservation in selected patients with multicentric tumors. Presentation of case: We report the case of a 48-year-old woman presenting with a multicentric breast cancer and successfully treated with an oncoplastic technique consisting in three radical lumpectomies followed by breast reshaping and simultaneous contralateral symmetrization. Discussion: According to our experience, oncoplastic conserving breast surgery could represent a better option than the combination of mastectomy, reconstruction and radiation therapy, in terms of quality of life for selected patients affected by multicentric breast cancer. Conclusion: The surgical treatment for multicentric breast cancers remains controversial even though emerging evidences show good oncological and aesthetic outcomes following oncoplastic conserving breast surgery.
Language	English
Publishing date	2016-09-28
Publishing country	Netherlands
Document type	Journal Article
ISSN	2210-2612
ISSN	2210-2612
DOI	10.1016/j.ijscr.2016.09.037
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Article: A rare case of true carcinosarcoma of the breast.

Accurso, Antonello / Ciancia, Giuseppe / Della Corte, Gianni Antonio / Reale, Paola / Accardo, Giuseppe / Salerno, Carmela / Bordoni, Daniele / Falco, Giuseppe / Rocco, Nicola

International journal of surgery case reports

2016 Volume 21, Page(s) 125–128

Abstract: Background: True carcinosarcoma of the breast is an extremely rare condition, accounting for 0.08-0.2% of all breast malignancies. The correct definition of this tumor requires both a carcinomatous component and a malignant non-epithelial component of ... ...

Abstract	Background: True carcinosarcoma of the breast is an extremely rare condition, accounting for 0.08-0.2% of all breast malignancies. The correct definition of this tumor requires both a carcinomatous component and a malignant non-epithelial component of mesenchymal origin, without evidence of a transition zone between the two elements. Case presentation: We present a case of a 49-year-old woman presenting with a 4cm mass at the level of her left breast upper-outer quadrant with a histologic diagnosis of true carcinosarcoma of the breast. Discussion: The most appropriate therapeutic regimens for breast carcinosarcoma are still unclear because of the rarity of this condition, but Breast Conserving Treatment (BCT) followed by adjuvant chemotherapy seems to provide a prognosis equalling that of usual Invasive Ductal Carcinoma of the breast.
Language	English
Publishing date	2016-03-10
Publishing country	Netherlands
Document type	Journal Article
ISSN	2210-2612
ISSN	2210-2612
DOI	10.1016/j.ijscr.2016.03.004
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Article: Primary angiosarcoma of the breast.

Bordoni, Daniele / Bolletta, Elisa / Falco, Giuseppe / Cadenelli, Pierfrancesco / Rocco, Nicola / Tessone, Ariel / Guarino, Stefania / Accurso, Antonello / Amato, Bruno / Magalotti, Cesare

International journal of surgery case reports

2016 Volume 20S, Page(s) 12–15

Abstract: Primary angiosarcoma (AS) of the breast is a rare neoplasia that is not related to radiation exposure. It represents less than 0.05% of all malignant breast tumors. This lesion is characterized by aggressive patterns and poor prognosis and by the absence ...

Abstract	Primary angiosarcoma (AS) of the breast is a rare neoplasia that is not related to radiation exposure. It represents less than 0.05% of all malignant breast tumors. This lesion is characterized by aggressive patterns and poor prognosis and by the absence of typical features at radiologic examination. Currently there are not evidence-based guidelines regarding surgical and adjuvant treatment for this tumor even though wide surgical resection followed by chemo- radiotherapy appears to improve both disease free survival and overall survival. The aim of this study was to analyze the available series of AS patients suggesting the most reliable treatment options for this rare neoplasia.
Language	English
Publishing date	2016-02-03
Publishing country	Netherlands
Document type	Journal Article
ISSN	2210-2612
ISSN	2210-2612
DOI	10.1016/j.ijscr.2016.02.003
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