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Book ; Online: Human Capital versus Basic Income : Ideology and Models for Anti-Poverty Programs in Latin America

Borges, Fabian

2022

Keywords	Politics & government ; Central government policies ; Political structure & processes ; Political ideologies ; Conditional Cash Transfers ; CCTs ; social policy ; anti-poverty programs ; Latin America, Latin American politics
Size	1 electronic resource (288 pages)
Publisher	University of Michigan Press
Document type	Book ; Online
Note	English ; Open Access
HBZ-ID	HT021289861
ISBN	9780472129805 ; 0472129805
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article: Assessing the habitat suitability of agricultural landscapes for characteristic breeding bird guilds using landscape metrics

Borges, Friederike

Environmental monitoring and assessment, 189: 166

2017

Abstract: Many of the processes behind the decline of farmland birds can be related to modifications in landscape structure (composition and configuration), which can partly be expressed quantitatively with measurable or computable indices, i.e. landscape metrics. ...

Institution	Leibniz-Zentrum für Agrarlandschaftsforschung
Abstract	Many of the processes behind the decline of farmland birds can be related to modifications in landscape structure (composition and configuration), which can partly be expressed quantitatively with measurable or computable indices, i.e. landscape metrics. This paper aims to identify statistical relationships between the occurrence of birds and the landscape structure. We present a method that combines two comprehensive procedures: the “landscape-centred approach” and “guild classification”. Our study is based on more than 20,000 individual bird observations based on a 4-year bird monitoring approach in a typical agricultural area in the north-eastern German lowlands. Five characteristic bird guilds, each with three characteristic species, are defined for the typical habitat types of that area: farmland, grassland, hedgerow, forest and settlement. The suitability of each sample plot for each guild is indicated by the level of persistence (LOP) of occurrence of three respective species. Thus, the sample plots can be classified as “preferred” or “less preferred” depending on the lower and upper quartiles of the LOP values. The landscape structure is characterized by 16 different landscape metrics expressing various aspects of landscape composition and configuration. For each guild, the three landscape metrics with the strongest rank correlation with the LOP values and that are not mutually dependent were identified. For four of the bird guilds, the classification success was better than 80%, compared with only 66% for the grassland bird guild. A subset of six landscape metrics proved to be the most meaningful and sufficiently classified the sample areas with respect to bird guild suitability. In addition, derived logistic functions allowed the production of guild-specific habitat suitability maps for the whole landscape. The analytical results show that the proposed approach is appropriate to assess the habitat suitability of agricultural landscapes for characteristic bird guilds.
Keywords	Binary logistic regression ; Bird monitoring ; Landscape assessment ; Landscape composition ; Landscape configuration ; Moving windows
Language	English
Document type	Article
Database	Repository for Life Sciences

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Article ; Online: Epigenetic control of transposons during plant reproduction: From meiosis to hybrid seeds.

Pachamuthu, Kannan / Borges, Filipe

Current opinion in plant biology

2023 Volume 75, Page(s) 102419

Abstract: The regulation of transposable elements (TEs) requires overlapping epigenetic modifications that must be reinforced every cell division and generation. In plants, this is achieved by multiple pathways including small RNAs, DNA methylation, and repressive ...

Abstract	The regulation of transposable elements (TEs) requires overlapping epigenetic modifications that must be reinforced every cell division and generation. In plants, this is achieved by multiple pathways including small RNAs, DNA methylation, and repressive histone marks that act together to control TE expression and activity throughout the entire life cycle. However, transient TE activation is observed during reproductive transitions as a result of epigenome reprogramming, thus providing windows of opportunity for TE proliferation and epigenetic novelty. Ultimately, these events may originate complex TE-driven transcriptional networks or cell-to-cell communication strategies via mobile small RNAs. In this review, we discuss recent findings and current understanding of TE regulation during sexual plant reproduction, and its implications for fertility, early seed development, and epigenetic inheritance.
MeSH term(s)	Meiosis/genetics ; Seeds/genetics ; Reproduction/genetics ; Cell Communication ; Epigenesis, Genetic
Language	English
Publishing date	2023-07-20
Publishing country	England
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	1418472-2
ISSN	1879-0356 ; 1369-5266
ISSN (online)	1879-0356
ISSN	1369-5266
DOI	10.1016/j.pbi.2023.102419
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Secure Aggregation Protocol Based on DC-Nets and Secret Sharing for Decentralized Federated Learning.

Pereira, Diogo / Reis, Paulo Ricardo / Borges, Fábio

Sensors (Basel, Switzerland)

2024 Volume 24, Issue 4

Abstract: In the era of big data, millions and millions of data are generated every second by different types of devices. Training machine-learning models with these data has become increasingly common. However, the data used for training are often sensitive and ... ...

Abstract	In the era of big data, millions and millions of data are generated every second by different types of devices. Training machine-learning models with these data has become increasingly common. However, the data used for training are often sensitive and may contain information such as medical, banking, or consumer records, for example. These data can cause problems in people's lives if they are leaked and also incur sanctions for companies that leak personal information for any reason. In this context, Federated Learning emerges as a solution to the privacy of personal data. However, even when only the gradients of the local models are shared with the central server, some attacks can reconstruct user data, allowing a malicious server to violate the FL principle, which is to ensure the privacy of local data. We propose a secure aggregation protocol for Decentralized Federated Learning, which does not require a central server to orchestrate the aggregation process. To achieve this, we combined a Multi-Secret-Sharing scheme with a Dining Cryptographers Network. We validate the proposed protocol in simulations using the MNIST handwritten digits dataset. This protocol achieves results comparable to Federated Learning with the FedAvg protocol while adding a layer of privacy to the models. Furthermore, it obtains a timing performance that does not significantly affect the total training time, unlike protocols that use Homomorphic Encryption.
Language	English
Publishing date	2024-02-17
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s24041299
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Serial cultures in invert emulsion and monophase systems for microbial community shaping and propagation.

Dijamentiuk, Alexis / Mangavel, Cécile / Gapp, Chloé / Elfassy, Annelore / Revol-Junelles, Anne-Marie / Borges, Frédéric

Microbial cell factories

2024 Volume 23, Issue 1, Page(s) 50

Abstract: Background: Microbial communities harbor important biotechnological potential in diverse domains, however, the engineering and propagation of such communities still face both knowledge and know-how gaps. More specifically, culturing tools are needed to ... ...

Abstract	Background: Microbial communities harbor important biotechnological potential in diverse domains, however, the engineering and propagation of such communities still face both knowledge and know-how gaps. More specifically, culturing tools are needed to propagate and shape microbial communities, to obtain desired properties, and to exploit them. Previous work suggested that micro-confinement and segregation of microorganisms using invert (water-in-oil, w/o) emulsion broth can shape communities during propagation, by alleviating biotic interactions and inducing physiological changes in cultured bacteria. The present work aimed at evaluating invert emulsion and simple broth monophasic cultures for the propagation and shaping of bacterial communities derived from raw milk in a serial propagation design. Results: The monophasic setup resulted in stable community structures during serial propagation, whereas the invert emulsion system resulted in only transiently stable structures. In addition, different communities with different taxonomic compositions could be obtained from a single inoculum. Furthermore, the implementation of invert emulsion systems has allowed for the enrichment of less abundant microorganisms and consequently facilitated their isolation on culture agar plates. Conclusions: The monophasic system enables communities to be propagated in a stable manner, whereas the invert emulsion system allowed for the isolation of less abundant microorganisms and the generation of diverse taxonomic compositions from a single inoculum.
MeSH term(s)	Emulsions ; Bacteria ; Microbiota ; Biotechnology ; Water
Chemical Substances	Emulsions ; Water (059QF0KO0R)
Language	English
Publishing date	2024-02-14
Publishing country	England
Document type	Journal Article
ZDB-ID	2091377-1
ISSN	1475-2859 ; 1475-2859
ISSN (online)	1475-2859
ISSN	1475-2859
DOI	10.1186/s12934-024-02322-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Dual action of benzaldehydes: Inhibiting quorum sensing and enhancing antibiotic efficacy for controlling Pseudomonas aeruginosa biofilms.

Leitão, Miguel M / Vieira, Tatiana F / Sousa, Sérgio F / Borges, Fernanda / Simões, Manuel / Borges, Anabela

Microbial pathogenesis

2024 Volume 191, Page(s) 106663

Abstract: Quorum sensing (QS) has a central role in biofilm lifestyle and antimicrobial resistance, and disrupting these signaling pathways is a promising strategy to control bacterial pathogenicity and virulence. In this study, the efficacy of three structurally ... ...

Abstract	Quorum sensing (QS) has a central role in biofilm lifestyle and antimicrobial resistance, and disrupting these signaling pathways is a promising strategy to control bacterial pathogenicity and virulence. In this study, the efficacy of three structurally related benzaldehydes (4-hydroxybenzaldehyde, 4-hydroxy-3-methoxybenzaldehyde (vanillin) and 4-hydroxy-3,5-dimethoxybenzaldehyde (syringaldehyde)) in disrupting the las and pqs systems of Pseudomonas aeruginosa was investigated using bioreporter strains and computational simulations. Additionally, these benzaldehydes were combined with tobramycin and ciprofloxacin antibiotics to evaluate their ability to increase antibiotic efficacy in preventing and eradicating P. aeruginosa biofilms. To this end, the total biomass, metabolic activity and culturability of the biofilm cells were determined. In vitro assays results indicated that the aromatic aldehydes have potential to inhibit the las and pqs systems by > 80 %. Molecular docking studies supported these findings, revealing the aldehydes binding in the same pocket as the natural ligands or receptor proteins (LasR, PQSA, PQSE, PQSR). Benzaldehydes were shown to act as virulence factor attenuators, with vanillin achieving a 48 % reduction in pyocyanin production. The benzaldehyde-tobramycin combination led not only to a 60 % reduction in biomass production but also to a 90 % reduction in the metabolic activity of established biofilms. A similar result was observed when benzaldehydes were combined with ciprofloxacin. 4-Hydroxybenzaldehyde demonstrated relevant action in increasing biofilm susceptibility to ciprofloxacin, resulting in a 65 % reduction in biomass. This study discloses, for the first time, that the benzaldehydes studied are potent QS inhibitors and also enhancers of antibiotics antibiofilm activity against P. aeruginosa.
Language	English
Publishing date	2024-04-26
Publishing country	England
Document type	Journal Article
ZDB-ID	632772-2
ISSN	1096-1208 ; 0882-4010
ISSN (online)	1096-1208
ISSN	0882-4010
DOI	10.1016/j.micpath.2024.106663
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Article ; Online: Propargylamine: an important moiety in drug discovery.

Carneiro, Aitor / Uriarte, Eugenio / Borges, Fernanda / Matos, Maria João

Future medicinal chemistry

2023 Volume 15, Issue 2, Page(s) 211–224

Abstract: Propargylamine is a chemical moiety whose properties have made it a widely distributed group within the fields of medicinal chemistry and chemical biology. Its particular reactivity has traditionally popularized the preparation of propargylamine ... ...

Abstract	Propargylamine is a chemical moiety whose properties have made it a widely distributed group within the fields of medicinal chemistry and chemical biology. Its particular reactivity has traditionally popularized the preparation of propargylamine derivatives using a large variety of synthetic strategies, which have facilitated the access to these compounds for the study of their biomedical potential. This review comprehensively covers and analyzes the applications that propargylamine-based derivatives have achieved in the drug discovery field, both from a medicinal chemistry perspective and from a chemical biology-oriented approach. The principal therapeutic fields where propargylamine-based compounds have made an impact are identified, and a discussion of their influence and growing potential is included.
MeSH term(s)	Pargyline/pharmacology ; Pargyline/chemistry ; Drug Discovery ; Propylamines/chemistry
Chemical Substances	propargylamine (2450-71-7) ; Pargyline (9MV14S8G3E) ; Propylamines
Language	English
Publishing date	2023-02-21
Publishing country	England
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ISSN	1756-8927
ISSN (online)	1756-8927
DOI	10.4155/fmc-2022-0243
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: On Acquisition Parameters and Processing Techniques for Interparticle Contact Detection in Granular Packings Using Synchrotron Computed Tomography.

Alvarez-Borges, Fernando / Ahmed, Sharif / Atwood, Robert C

Journal of imaging

2022 Volume 8, Issue 5

Abstract: X-ray computed tomography (XCT) is regularly employed in geomechanics to non-destructively measure the solid and pore fractions of soil and rock from reconstructed 3D images. With the increasing availability of high-resolution XCT imaging systems, ... ...

Abstract	X-ray computed tomography (XCT) is regularly employed in geomechanics to non-destructively measure the solid and pore fractions of soil and rock from reconstructed 3D images. With the increasing availability of high-resolution XCT imaging systems, researchers now seek to measure microfabric parameters such as the number and area of interparticle contacts, which can then be used to inform soil behaviour modelling techniques. However, recent research has evidenced that conventional image processing methods consistently overestimate the number and area of interparticle contacts, mainly due to acquisition-driven image artefacts. The present study seeks to address this issue by systematically assessing the role of XCT acquisition parameters in the accurate detection of interparticle contacts. To this end, synchrotron XCT has been applied to a hexagonal close-packed arrangement of glass pellets with and without a prescribed separation between lattice layers. Different values for the number of projections, exposure time, and rotation range have been evaluated. Conventional global grey value thresholding and novel U-Net segmentation methods have been assessed, followed by local refinements at the presumptive contacts, as per recently proposed contact detection routines. The effect of the different acquisition set-ups and segmentation techniques on contact detection performance is presented and discussed, and optimised workflows are proposed.
Language	English
Publishing date	2022-05-12
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2824270-1
ISSN	2313-433X ; 2313-433X
ISSN (online)	2313-433X
ISSN	2313-433X
DOI	10.3390/jimaging8050135
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Specificities and Dynamics of Transposable Elements in Land Plants.

Mhiri, Corinne / Borges, Filipe / Grandbastien, Marie-Angèle

Biology

2022 Volume 11, Issue 4

Abstract: Transposable elements (TEs) are important components of most plant genomes. These mobile repetitive sequences are highly diverse in terms of abundance, structure, transposition mechanisms, activity and insertion specificities across plant species. This ... ...

Abstract	Transposable elements (TEs) are important components of most plant genomes. These mobile repetitive sequences are highly diverse in terms of abundance, structure, transposition mechanisms, activity and insertion specificities across plant species. This review will survey the different mechanisms that may explain the variability of TE patterns in land plants, highlighting the tight connection between TE dynamics and host genome specificities, and their co-evolution to face and adapt to a changing environment. We present the current TE classification in land plants, and describe the different levels of genetic and epigenetic controls originating from the plant, the TE itself, or external environmental factors. Such overlapping mechanisms of TE regulation might be responsible for the high diversity and dynamics of plant TEs observed in nature.
Language	English
Publishing date	2022-03-23
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2661517-4
ISSN	2079-7737
ISSN	2079-7737
DOI	10.3390/biology11040488
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Far-offset detection of normal modes and diving waves

Borges, Filipe / Landrø, Martin

A case study from the Valhall Field, southern North Sea

2022

Abstract: The use of permanent arrays for continuous reservoir monitoring has become a reality in the past decades, with Ekofisk and Valhall being its flagships. One of the possibilities when such a solution is available is to passively record data while ... ...

Abstract	The use of permanent arrays for continuous reservoir monitoring has become a reality in the past decades, with Ekofisk and Valhall being its flagships. One of the possibilities when such a solution is available is to passively record data while acquisitions with an active source are ongoing in nearby areas. These recordings might contain ultrafar-offset data (more than 30 km), which are hardly used in standard reservoir exploration and monitoring because they are mostly a combination of normal modes, deep reflections, and diving waves. We present data from the Valhall life-of-field seismic array, recorded while an active seismic survey was acquired at Ekofisk, in April 2014. Despite the lack of control on source firing time and position, analysis of the data indicates that the normal modes are remarkably clear, overcoming the ambient noise in the field. The normal modes can be well explained by a two-layer acoustic model, whereas a combination of diving waves and refracted waves can be fairly well reproduced with a regional 1D velocity model. We suggest a method to use far-offset recordings to monitor changes in shallow sediments between source and receivers, with and without a coherent seismic source in the area.
Language	English
Publishing date	2022-03-01
Publisher	SEG (Society of Exploration Geophysicists)
Publishing country	de
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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