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  1. AU="Borrego-Jiménez, Jaime"
  2. AU="Kaoru Dohi"
  3. AU="Tornai, Gábor J"
  4. AU="D'Avella, Christopher"
  5. AU="Lim, Boon L."
  6. AU="Heselden, Marie"
  7. AU=Dias?Polak David
  8. AU="Shahid Umar"
  9. AU="Abu-Shmais, Alexandria A"
  10. AU="Takenaka, Haruka"
  11. AU="Bramley, Andrea"
  12. AU="Sang Hong Lee"

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  1. Artikel: Enteroinvasive bacteria. Local study in specialized clinical care.

    Martín-Rodríguez, María Del Mar / Borrego-Jiménez, Jaime / Rodríguez-Guerrero, Enrique / Gutiérrez-Fernández, José

    Gastroenterologia y hepatologia

    2022  Band 46, Heft 7, Seite(n) 554–556

    Titelübersetzung Bacterias enteroinvasivas. Estudio local en atención clínica especializada.
    Mesh-Begriff(e) Humans ; Escherichia coli Infections ; Escherichia coli ; Bacteria
    Sprache Spanisch
    Erscheinungsdatum 2022-09-05
    Erscheinungsland Spain
    Dokumenttyp Case Reports
    ZDB-ID 632502-6
    ISSN 0210-5705
    ISSN 0210-5705
    DOI 10.1016/j.gastrohep.2022.08.004
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Accuracy of Three Serological Techniques for the Diagnosis of Imported Schistosomiasis in Real Clinical Practice: Not All in the Same Boat.

    Luzón-García, María Pilar / Cabeza-Barrera, María Isabel / Lozano-Serrano, Ana Belén / Soriano-Pérez, Manuel Jesús / Castillo-Fernández, Nerea / Vázquez-Villegas, José / Borrego-Jiménez, Jaime / Salas-Coronas, Joaquín

    Tropical medicine and infectious disease

    2023  Band 8, Heft 2

    Abstract: Schistosomiasis is a neglected tropical disease despite of being a major public health problem affecting nearly 240 million people in the world. Due to the migratory flow from endemic countries to Western countries, an increasing number of cases is being ...

    Abstract Schistosomiasis is a neglected tropical disease despite of being a major public health problem affecting nearly 240 million people in the world. Due to the migratory flow from endemic countries to Western countries, an increasing number of cases is being diagnosed in non-endemic areas, generally in migrants or people visiting these areas. Serology is the recommended method for screening and diagnosis of schistosomiasis in migrants from endemic regions. However, serological techniques have a highly variable sensitivity. The aim of this study was to evaluate retrospectively the sensitivity of three different serological tests used in real clinical practice for the screening and diagnosis of imported schistosomiasis in sub-Saharan migrant patients, using the detection of schistosome eggs in urine, faeces or tissues as the gold standard. We evaluated three different serological techniques in 405 sub-Saharan patients with confirmed schistosomiasis treated between 2004 and 2022: an enzyme-linked immunosorbent assay (ELISA), an indirect haemagglutination assay (IHA) and an immunochromatographic test (ICT). The overall sensitivity values obtained with the different techniques were: 44.4% for IHA, 71.2% for ELISA and 94.7% for ICT, respectively. According to species, ICT showed the highest sensitivity (
    Sprache Englisch
    Erscheinungsdatum 2023-01-19
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ISSN 2414-6366
    ISSN (online) 2414-6366
    DOI 10.3390/tropicalmed8020073
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Estimation of parasitaemia in imported falciparum malaria using the results of a combined rapid diagnostic test. No big help from haematological parameters.

    Soriano-Pérez, Manuel Jesús / Castillo-Fernández, Nerea / Lozano-Serrano, Ana Belén / Luzón-García, María Pilar / Vázquez-Villegas, José / Cabeza-Barrera, María Isabel / Borrego-Jiménez, Jaime / Giménez-López, María José / Salas-Coronas, Joaquín

    Malaria journal

    2023  Band 22, Heft 1, Seite(n) 351

    Abstract: Background: Microscopy continues to be the mainstay for the evaluation of parasitaemia in malaria but requires laboratory support and microbiological experience. Other fast and simple methods are necessary.: Methods: A retrospective observational ... ...

    Abstract Background: Microscopy continues to be the mainstay for the evaluation of parasitaemia in malaria but requires laboratory support and microbiological experience. Other fast and simple methods are necessary.
    Methods: A retrospective observational study of imported malaria treated from July-2007 to December-2020 was carried out to evaluate the association between the degree of parasitaemia and both rapid diagnostic tests (RDT) reactivity patterns and haematological parameters. Plasmodium falciparum monoinfections diagnosed by peripheral blood smear and/or polymerase chain reaction (PCR),which also had a positive RDT result in the same blood sample, were included in the study.
    Results: A total of 273 patients were included. Most of them were male (n = 256; 93.8%) and visiting friends and relatives (VFR) travellers (n = 252; 92.3%). Patients with plasmodial lactate dehydrogenase (pLDH) or aldolase and histidine-rich protein 2 (HRP-2) co-reactivity (Pan/Pf pattern) had a parasitaemia range between 0 and 37% while those with just HRP-2 reactivity (P. falciparum pattern) had ranges between 0 and 1%. Not a single case of P. falciparum pattern was found for parasitaemia ranges greater than 1%, showing a negative predictive value of 100% for high parasitaemia. All the correlations between haematological parameters and parasitaemia resulted to be weak, with a maximum rho coefficient of -0.35 for lymphocytes and platelets, and of 0.40 for neutrophils-to-lymphocytes count ratio. Multivariate predictive models were constructed reflecting a poor predictive capacity.
    Conclusions: The reactivity pattern of RDT allows a rapid semi-quantitative assessment of P. falciparum parasitaemia in travellers with imported malaria, discriminating patients with lower parasite loads. Haematological parameters were not able to estimate parasitaemia with sufficient precision.
    Mesh-Begriff(e) Humans ; Male ; Female ; Rapid Diagnostic Tests ; Reagent Kits, Diagnostic ; Sensitivity and Specificity ; Malaria, Falciparum/diagnosis ; Malaria, Falciparum/parasitology ; Malaria/parasitology ; Plasmodium falciparum ; Parasitemia/diagnosis ; Diagnostic Tests, Routine/methods ; Antigens, Protozoan ; Protozoan Proteins
    Chemische Substanzen Reagent Kits, Diagnostic ; Antigens, Protozoan ; Protozoan Proteins
    Sprache Englisch
    Erscheinungsdatum 2023-11-16
    Erscheinungsland England
    Dokumenttyp Observational Study ; Journal Article
    ZDB-ID 2091229-8
    ISSN 1475-2875 ; 1475-2875
    ISSN (online) 1475-2875
    ISSN 1475-2875
    DOI 10.1186/s12936-023-04781-2
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Mycoplasma genitalium: Using a commercial molecular technique that facilitates rapid detection of mutations associated with resistance to macrolides.

    Borrego-Jiménez, Jaime / Foronda Garcia-Hidalgo, Carla / Navarro-Marí, José María / Gutiérrez-Fernández, José

    Enfermedades infecciosas y microbiologia clinica (English ed.)

    2019  Band 38, Heft 2, Seite(n) 91–92

    Titelübersetzung Mycoplasma genitalium: utilización de una técnica molecular comercial que facilita el análisis rápido de mutaciones asociadas con resistencia a macrólidos.
    Mesh-Begriff(e) Anti-Bacterial Agents/pharmacology ; Drug Resistance, Bacterial/genetics ; Humans ; Macrolides/pharmacology ; Mutation ; Mycoplasma genitalium/cytology ; Mycoplasma genitalium/drug effects
    Chemische Substanzen Anti-Bacterial Agents ; Macrolides
    Sprache Spanisch
    Erscheinungsdatum 2019-04-20
    Dokumenttyp Case Reports ; Journal Article
    ISSN 2529-993X
    ISSN (online) 2529-993X
    DOI 10.1016/j.eimc.2019.03.005
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Susceptibility evolution to antibiotics of Enterobacter cloacae, Morganella morganii, Klebsiella aerogenes and Citrobacter freundii involved in urinary tract infections: an 11-year epidemiological surveillance study.

    Jiménez-Guerra, Gemma / Borrego-Jiménez, Jaime / Gutiérrez-Soto, Blanca / Expósito-Ruiz, Manuela / Navarro-Marí, José María / Gutiérrez-Fernández, José

    Enfermedades infecciosas y microbiologia clinica (English ed.)

    2019  Band 38, Heft 4, Seite(n) 166–169

    Abstract: Introduction: The objective of this study was to analyse the susceptibility to antibiotic of Citrobacter freundii, Klebsiella aerogenes, Enterobacter cloacae, Serratia marcescens, Providencia stuartii and Morganella morganii (CESPM group), detected in ... ...

    Titelübersetzung Evolución de la sensibilidad a los antibióticos de Enterobacter cloacae, Morganella morganii, Klebsiella aerogenes y Citrobacter freundii causantes de infecciones del tracto urinario: un estudio de vigilancia epidemiológica de 11 años.
    Abstract Introduction: The objective of this study was to analyse the susceptibility to antibiotic of Citrobacter freundii, Klebsiella aerogenes, Enterobacter cloacae, Serratia marcescens, Providencia stuartii and Morganella morganii (CESPM group), detected in urine cultures.
    Methods: Between 2006 and 2016 we analyzed CESPM group Enterobacteria isolated from urine cultures from both primary health-care centers and Hospital Virgen de las Nieves (Granada). We studied the susceptibility to aminoglycosides, fosfomycin, nitrofurantoin, quinolones, piperacillin/tazobactam, cefepime, imipenem and trimethoprim/sulfamethoxazole following CLSI interpretation criteria.
    Results: A total of 736 isolates were studied: 30.57% E. cloacae, 23.50% M. morganii, 20.38% K. aerogenes, 10.32% C. freundii, 8.83% S. marcescens and 6.38% P. stuartii. A significant decrease in the antibiotic susceptibility was observed. Gentamicin, ciprofloxacin, imipenem and cefepime showed susceptibility over 80%.
    Conclusions: E. cloacae, M. morganii and K. aerogenes were the most common isolates. Cefepime and imipenem are still a good empiric therapeutic alternative given its activity in vitro.
    Mesh-Begriff(e) Anti-Bacterial Agents/pharmacology ; Citrobacter freundii/drug effects ; Drug Resistance, Bacterial ; Enterobacter aerogenes/drug effects ; Enterobacter cloacae/drug effects ; Humans ; Microbial Sensitivity Tests ; Morganella morganii/drug effects ; Providencia/drug effects ; Serratia marcescens/drug effects ; Spain ; Urinary Tract Infections/microbiology
    Chemische Substanzen Anti-Bacterial Agents
    Sprache Spanisch
    Erscheinungsdatum 2019-10-10
    Dokumenttyp Journal Article
    ISSN 2529-993X
    ISSN (online) 2529-993X
    DOI 10.1016/j.eimc.2019.07.010
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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