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  1. Article: Encapsulated Hematoma of the Bartholin's Glandule.

    Mustaqe, Petraq / Ibra, Artemis / Verras, Georgios-Ioannis / Iliopoulos, Fotios / Tchabashvili, Levan / Tasios, Konstantinos / Leivaditis, Vasileios / Bouchagier, Konstantinos / Mulita, Francesk

    Materia socio-medica

    2024  Volume 35, Issue 4, Page(s) 339–341

    Abstract: Bartholin's glands are important organs of the female reproductive system. These glands have the function of producing an alkaline mucoid secretion, which helps in vaginal and vulvar lubrication. There are several types of lesions that can be identified ... ...

    Abstract Bartholin's glands are important organs of the female reproductive system. These glands have the function of producing an alkaline mucoid secretion, which helps in vaginal and vulvar lubrication. There are several types of lesions that can be identified in these anatomical structures, where in most cases presented for medical examination, cysts and abscesses predominate. This is the presentation of a clinical case of a 55-year-old patient, who is presented to the surgeon for her complaints. Once the woman is examined, diagnosed, and treated adequately, she is taken into consideration for presenting her case in this study, while maintaining confidentiality. The presented clinical case provides a clinical framework not easy to establish an accurate diagnosis of a Bartholin gland cyst. Careful physical examination by the surgeon and careful preparation with electrosurgery verified the cyst-hematoma left and just above the posterior fornix, where some material was taken from the cyst capsule and hematoma and sent for histological examination. The histological response concluded with cystic hematoma of the Bartholin gland. Cystic lesions of the vagina are relatively common and usually represent a benign condition. Ways of managing Bartholin gland cysts vary depending on the discomfort they bring to the patient as well as the size or even the anatomical extent of the cystic lesion. However, the physical examination, with a careful inspection by the surgeon, combined with the imaging examinations, requires a biopsy examination, which is the confirmation of the diagnosis.
    Language English
    Publishing date 2024-01-26
    Publishing country Bosnia and Herzegovina
    Document type Case Reports
    ISSN 1512-7680
    ISSN 1512-7680
    DOI 10.5455/msm.2023.35.339-341
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Cold Reactive Proteins in Cardiovascular Surgery.

    Panagiotopoulos, Ioannis / Mulita, Francesk / Verras, Georgios-Ioannis / Katinioti, Anastasia / Samaras, Angelos / Tasios, Konstantinos / Bouchagier, Konstantinos / Triantafyllou, Konstantinos

    Materia socio-medica

    2023  Volume 34, Issue 4, Page(s) 301

    Abstract: Background: According to the literature, Cryoglobins, Cold Agglutinins, Donath-Landsteiner antibodies, and Cryofibrinogen arethe 4 types of Cold-Reactive proteins described.: Objective: The aim of the study was to show the role of these proteins ... ...

    Abstract Background: According to the literature, Cryoglobins, Cold Agglutinins, Donath-Landsteiner antibodies, and Cryofibrinogen arethe 4 types of Cold-Reactive proteins described.
    Objective: The aim of the study was to show the role of these proteins cardiovascular surgery.
    Case presentation: A 57-year-old male patient with a history of myocardial infarction 6 years ago, heavy smoker until 1 year ago, with diabetes, was admitted to the hospital for a surgical confrontation of coronary disease. He reports that for1-month symptoms are deteriorating (NYHA III). The history of the patient does not include either hematopoietic system or connective tissue diseases or recent viral infection. Angiographic control showed total obstruction of the small branch. The patient underwent median sternotomy. Suspension of the left sternum. Mobilization of the left internal mammary artery. Concomitant reception of left great saphenous vein. Intubation of ascending aorta and right atrium - vena cava with acatheter of two steps. He was extubated at the 10th post-surgical hour. Smooth post-surgical progression, with no signs of brain, myocardial or renal failure. The patient was discharged on the 5th post-surgical day.
    Conclusion: Independently of the technique that is used, the systemic temperature must be maintained duringthe cardiopulmonary bypass above the temperature threshold activity of the cold-reactiveproteins.
    Language English
    Publishing date 2023-03-16
    Publishing country Bosnia and Herzegovina
    Document type Case Reports
    ISSN 1512-7680
    ISSN 1512-7680
    DOI 10.5455/msm.2022.34.301-304
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Outcomes at 10-Year Follow-Up after Roux-en-Y Gastric Bypass, Biliopancreatic Diversion, and Sleeve Gastrectomy.

    Verras, Georgios-Ioannis / Mulita, Francesk / Pouwels, Sjaak / Parmar, Chetan / Drakos, Nikolas / Bouchagier, Konstantinos / Kaplanis, Charalampos / Skroubis, George

    Journal of clinical medicine

    2023  Volume 12, Issue 15

    Abstract: Introduction: Morbid obesity is a well-defined chronic disease, the incidence of which is constantly rising. Surgical treatment of morbid obesity has produced superior outcomes compared to conventional weight loss measures. Currently, there is a gap in ... ...

    Abstract Introduction: Morbid obesity is a well-defined chronic disease, the incidence of which is constantly rising. Surgical treatment of morbid obesity has produced superior outcomes compared to conventional weight loss measures. Currently, there is a gap in the literature regarding long-term outcomes. Our single-institution, retrospective cohort study aims to evaluate weight loss outcomes, comorbidity reduction, and adverse effects at 10 years following Roux-en-Y Gastric Bypass (RYGB), Biliopancreatic Diversion (BPD), and Sleeve Gastrectomy (SG).
    Materials and methods: We included all consecutive patients with 10-year follow-up records operated on within our institution. The comparison was carried out on the average percentage of weight and BMI loss. Nausea and vomiting were evaluated through self-reporting Likert scales. Diabetes resolution and nutritional deficiencies were also evaluated.
    Results: A total of 490 patients from 1995 up to 2011 were included in our study. Of these, 322 underwent RYGB, 58 underwent long-limb BPD, 34 underwent laparoscopic RYGB with fundus excision, 47 underwent laparoscopic SG, and 29 underwent laparoscopic RYGB as a revision of prior SG. RYGB and BPD were significantly associated with higher percentages of weight loss (37.6% and 37.5%), but were not found to be independent predictors of weight loss. Nausea and vomiting were associated with SG and laparoscopic RYGB with fundus excision, more so than the other operations. No differences were observed regarding diabetes resolution and nutritional deficiencies.
    Conclusions: Longer follow-up reports are important for the comparison of outcomes between different types of bariatric operations. BPD and RYGB resulted in superior weight loss, with no observed differences in diabetes resolution and adverse outcomes.
    Language English
    Publishing date 2023-07-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12154973
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Embedment of the gastroduodenal artery stump into the jejunal serosa: A new technique aiming to prevent post-pancreatectomy hemorrhage.

    Klimopoulos, Serafeim / Charakopoulou, Alexandra / Pantelis, Athanasios / Bouchagier, Konstantinos

    Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique

    2019  Volume 26, Issue 4, Page(s) e32–e36

    Abstract: Post-pancreaticoduodenectomy hemorrhage has an estimated incidence of 5% and a mortality rate of 11-38%. Vascular erosion resulting from pancreatic leak and skeletonization of the arterial wall during pancreatic mobilization may be the two possible ... ...

    Abstract Post-pancreaticoduodenectomy hemorrhage has an estimated incidence of 5% and a mortality rate of 11-38%. Vascular erosion resulting from pancreatic leak and skeletonization of the arterial wall during pancreatic mobilization may be the two possible mechanisms responsible for this complication, which most commonly affects the gastroduodenal artery stump. A novel technique of wrapping up the gastroduodenal artery stump into the jejunal serosa to decrease postoperative hemorrhage is presented.
    MeSH term(s) Aged ; Digestive System Surgical Procedures/methods ; Duodenum/blood supply ; Duodenum/surgery ; Female ; Humans ; Jejunum/blood supply ; Jejunum/surgery ; Male ; Middle Aged ; Pancreatectomy/adverse effects ; Pancreatectomy/trends ; Pancreaticoduodenectomy/adverse effects ; Pancreaticoduodenectomy/trends ; Postoperative Hemorrhage/diagnosis ; Postoperative Hemorrhage/etiology ; Postoperative Hemorrhage/prevention & control ; Serous Membrane/blood supply ; Serous Membrane/surgery ; Stomach/blood supply ; Stomach/surgery
    Language English
    Publishing date 2019-12-27
    Publishing country Australia
    Document type Journal Article ; Technical Report
    ISSN 2561-8741
    ISSN (online) 2561-8741
    DOI 10.15586/jptcp.v26i4.652
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Mediastinal abscess and osteomyelitis as side effects of immunomodulatory treatment with fingolimod.

    Eforakopoulos, Fotios / Giovani, Maria / Mulita, Francesk / Koletsis, Efstratios / Zampakis, Petros / Verras, Georgios-Ioannis / Bouchagier, Konstantinos / Panagiotopoulos, Ioannis / Charokopos, Nikolaos

    Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery

    2022  Volume 19, Issue 2, Page(s) 109–112

    Language English
    Publishing date 2022-06-29
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2237053-5
    ISSN 1897-4252 ; 1731-5530
    ISSN (online) 1897-4252
    ISSN 1731-5530
    DOI 10.5114/kitp.2022.117503
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The role of deep learning in diagnosing colorectal cancer.

    Bousis, Dimitrios / Verras, Georgios-Ioannis / Bouchagier, Konstantinos / Antzoulas, Andreas / Panagiotopoulos, Ioannis / Katinioti, Anastasia / Kehagias, Dimitrios / Kaplanis, Charalampos / Kotis, Konstantinos / Anagnostopoulos, Christos-Nikolaos / Mulita, Francesk

    Przeglad gastroenterologiczny

    2023  Volume 18, Issue 3, Page(s) 266–273

    Abstract: Colon cancer is a major public health issue, affecting a growing number of individuals worldwide. Proper and early diagnosis of colon cancer is the necessary first step toward effective treatment and/or prevention of future disease relapse. Artificial ... ...

    Abstract Colon cancer is a major public health issue, affecting a growing number of individuals worldwide. Proper and early diagnosis of colon cancer is the necessary first step toward effective treatment and/or prevention of future disease relapse. Artificial intelligence and its subtypes, deep learning in particular, tend nowadays to have an expanding role in all fields of medicine, and diagnosing colon cancer is no exception. This report aims to summarize the entire application spectrum of deep learning in all diagnostic tests regarding colon cancer, from endoscopy and histologic examination to medical imaging and screening serologic tests.
    Language English
    Publishing date 2023-07-17
    Publishing country Poland
    Document type Journal Article ; Review
    ZDB-ID 2596134-2
    ISSN 1897-4317 ; 1895-5770
    ISSN (online) 1897-4317
    ISSN 1895-5770
    DOI 10.5114/pg.2023.129494
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Correlation between gynecological tumors and atherosclerotic diseases.

    Mulita, Francesk / Leivaditis, Vasileios / Dimopoulos, Platon / Ibra, Artemis / Iliopoulos, Fotios / Tasios, Konstantinos / Pitros, Christos / Kaplanis, Charalampos / Peteinaris, Angelis / Bouchagier, Konstantinos / Papadoulas, Spyros / Pitiakoudis, Michail

    Archives of medical sciences. Atherosclerotic diseases

    2023  Volume 8, Page(s) e118–e122

    Abstract: Gynecological cancer is among the leading causes of cancer-related mortality worldwide, with malignancies of the ovary, uterus, fallopian tube, cervix, vagina, and vulva making up 10-18% of all cancers diagnosed in women globally. Gynecological cancer ... ...

    Abstract Gynecological cancer is among the leading causes of cancer-related mortality worldwide, with malignancies of the ovary, uterus, fallopian tube, cervix, vagina, and vulva making up 10-18% of all cancers diagnosed in women globally. Gynecological cancer and atherosclerosis are two of the most frequent medical entities that afflict women worldwide; thus the possible correlations between them ought to be explored. Vulvar, cervical, vaginal, endometrial, and ovarian cancers have been found to have common points with atherosclerosis regarding their pathogenesis and predisposing factors. Obesity and metabolic syndrome, HPV infection, vitamin D deficiency, and increased telomere length constitute common ground between these two afflictions, which this article aims to analyze.
    Language English
    Publishing date 2023-12-30
    Publishing country Poland
    Document type Journal Article
    ISSN 2451-0629
    ISSN 2451-0629
    DOI 10.5114/amsad/176655
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Prevalence of stroke-related risk factors in Albania: a single-center experience.

    Mustaqe, Petraq / Dimopoulos, Platon / Dogjani, Agron / Leivaditis, Vasileios / Akrida, Ioanna / Panagiotopoulos, Ioannis / Katinioti, Anastasia / Kostopoulou, Ira-Eirini / Antzoulas, Andreas / Bouchagier, Konstantinos / Papadoulas, Spyros / Mulita, Francesk

    Archives of medical sciences. Atherosclerotic diseases

    2023  Volume 8, Page(s) e123–e127

    Abstract: Introduction: Stroke, a prominent global cause of mortality and disability, is broadly categorized into ischemic and hemorrhagic types. An epidemiological survey of stroke and its risk factors can help identify individuals at higher risk and therefore ... ...

    Abstract Introduction: Stroke, a prominent global cause of mortality and disability, is broadly categorized into ischemic and hemorrhagic types. An epidemiological survey of stroke and its risk factors can help identify individuals at higher risk and therefore promote stroke prevention strategies. The aim of this study was to estimate the current prevalence of stroke and evaluate stroke-associated risk factors in Albania.
    Material and methods: This was a single-center retrospective analysis conducted in Albania for the period from May 2015 to September 2021. Data were collected retrospectively through hospital records. Stroke was defined as sudden onset of a nonconvulsive and focal neurological deficit, and ischemic stroke was diagnosed using brain computed tomography (CT), magnetic resonance (MR) imaging, or both. We examined patient history characteristics encompassing demographics, stroke history, conventional vascular risk factors, and lifestyle-related risk factors.
    Results: The mean age of the 3860 patients was 74.6 ±10.4 years, and 73.5% were men. The prevalence of carotid stenosis, arrhythmia, obesity, and hypertension was significantly higher in males than in females (
    Conclusions: Our analysis underscores the male predominance (2.2 : 1) in stroke cases. Carotid and vertebral artery stenosis is a significant factor, emphasizing the life-saving potential of early intervention. Social and economic factors in Albania pose challenges, demanding comprehensive strategies. Prospective trials are crucial to explore intervention efficacy, and timing, and address socioeconomic impacts on timely stroke management.
    Language English
    Publishing date 2023-12-30
    Publishing country Poland
    Document type Journal Article
    ISSN 2451-0629
    ISSN 2451-0629
    DOI 10.5114/amsad/176811
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Association between perineural infiltrations and delayed gastric emptying after Whipple procedure for periampullary tumours, and the relationship with other clinicopathological factors and overall survival.

    Bouchagier, Konstantinos / Mulita, Francesk / Verras, Georgios-Ioannis / Nehr, Steffen / Perdikaris, Ioannis / Tasios, Konstantinos / Antzoulas, Andreas / Samaras, Angelos / Klimopoulos, Serafeim / Maroulis, Ioannis

    Przeglad gastroenterologiczny

    2023  Volume 19, Issue 1, Page(s) 89–96

    Abstract: Introduction: Pancreaticoduodenectomy is a major procedure. Delayed gastric emptying (DGE) is a frequent postoperative complication that is attributed to several factors.: Aim: To investigate the probable association between perineural infiltrations ... ...

    Abstract Introduction: Pancreaticoduodenectomy is a major procedure. Delayed gastric emptying (DGE) is a frequent postoperative complication that is attributed to several factors.
    Aim: To investigate the probable association between perineural infiltrations and DGE, and the effects on overall survival.
    Material and methods: A total of 123 patients who underwent pancreaticoduodenectomy were enrolled in the study. Factors like the presence of perineural infiltrations and post-operative DGE along with age, gender, presence of postoperative fistula, and grade of fistula and postoperative haemorrhage were analysed, and survival analyses were conducted.
    Results: The presence of perineural infiltrations is statistically associated with DGE occurrence (
    Conclusions: This is the first study that proves a statistically significant association between the presence of perineural infiltrations and the occurrence of DGE. Moreover, perineural infiltrations are an important independent prognostic factor for overall survival, along with other clinical factors.
    Language English
    Publishing date 2023-07-17
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2596134-2
    ISSN 1897-4317 ; 1895-5770
    ISSN (online) 1897-4317
    ISSN 1895-5770
    DOI 10.5114/pg.2023.129464
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Comparison of postoperative bleeding using harmonic scalpel and LigaSure in thyroid surgery: a 15-year single-centre retrospective study.

    Mulita, Francesk / Theofanis, George / Verras, Georgios-Ioannis / Liolis, Elias / Papanikos, Vasileios / Tchabashvili, Levan / Tasios, Konstantinos / Iliopoulos, Fotios / Tsilivigkos, Christos / Kehagias, Dimitrios / Kaplanis, Charalampos / Antzoulas, Andreas / Samaras, Angelos / Drakos, Nikolas / Panagiotopoulos, Ioannis / Leivaditis, Vasileios / Filis, Dimitrios / Maroulis, Ioannis / Bouchagier, Konstantinos /
    Michalaki, Marina

    Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina

    2023  Volume 20, Issue 2

    Abstract: Aim Thyroidectomy is the most common operation in the field of endocrine surgery. The aim of this study was to compare the use of LigaSure vessel (LS) and harmonic scalpel (HS) in 1653 total thyroidectomies between January 2008 and March of 2023, with ... ...

    Abstract Aim Thyroidectomy is the most common operation in the field of endocrine surgery. The aim of this study was to compare the use of LigaSure vessel (LS) and harmonic scalpel (HS) in 1653 total thyroidectomies between January 2008 and March of 2023, with regards to analysis of surgical bleeding complications duration the hospital stay and operative surgical time. Methods It is a retrospective analysis of a prospectively maintained database. Patients have been categorized into two groups: Group A included 718 patients from January 2008 to May 2013 when LS was used, and the Group B included 935 patients from June 2013 to March 2023 when HS was used. Results From the total of 14 postoperative bleeding cases that occurred in patients of Group A, only in 4 of them it was necessary to have a reoperation. The other 10 cases involved minor haemorrhages, while from the total of 6 postoperative bleeding cases that happened to patients of Group B, there were 4 cases that needed a reoperation (p-value >0.05) and 2 patients with minor haemorrhages. The postoperative evaluation of minor bleedings revealed statistically significant differences between the two groups (p-value < 0.05). The average hospital stay was similar in the two groups. Conclusion Both devices exhibit identical safety profiles in thyroidectomies specifically regarding major bleeding complications that require reoperation. Additionally, HS was found to be more effective at achieving haemostasis, especially in the subgroup of patients with thyroid carcinoma. The results of the present study may be useful for high-volume centres performing numerous thyroidectomies every day.
    Language English
    Publishing date 2023-08-01
    Publishing country Bosnia and Herzegovina
    Document type Journal Article
    ZDB-ID 2378942-6
    ISSN 1840-2445 ; 1840-2445
    ISSN (online) 1840-2445
    ISSN 1840-2445
    DOI 10.17392/1629-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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