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  1. Article: Establishing a Dedicated Lung Cancer Biobank at the University Center Hospital of Nice (France). Why and How?

    Washetine, Kevin / Heeke, Simon / Bonnetaud, Christelle / Kara-Borni, Mehdi / Ilié, Marius / Lassalle, Sandra / Butori, Catherine / Long-Mira, Elodie / Marquette, Charles Hugo / Cohen, Charlotte / Mouroux, Jérôme / Selva, Eric / Tanga, Virginie / Bence, Coraline / Félix, Jean-Marc / Gazoppi, Loic / Skhiri, Taycir / Gormally, Emmanuelle / Boucher, Pascal /
    Clément, Bruno / Dagher, Georges / Hofman, Véronique / Hofman, Paul

    Cancers

    2018  Volume 10, Issue 7

    Abstract: Lung cancer is the major cause of death from cancer in the world and its incidence is increasing in women. Despite the progress made in developing immunotherapies and therapies targeting genomic alterations, improvement in the survival rate of advanced ... ...

    Abstract Lung cancer is the major cause of death from cancer in the world and its incidence is increasing in women. Despite the progress made in developing immunotherapies and therapies targeting genomic alterations, improvement in the survival rate of advanced stages or metastatic patients remains low. Thus, urgent development of effective therapeutic molecules is needed. The discovery of novel therapeutic targets and their validation requires high quality biological material and associated clinical data. With this aim, we established a biobank dedicated to lung cancers. We describe here our strategy and the indicators used and, through an overall assessment, present the strengths, weaknesses, opportunities and associated risks of this biobank.
    Language English
    Publishing date 2018-06-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers10070220
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Measuring the contribution of tumor biobanks to research in oncology: surrogate indicators and bibliographic output.

    Hofman, Véronique / Ilie, Marius / Long, Elodie / Washetine, Kevin / Chabannon, Christian / Figarella-Branger, Dominique / Clément, Bruno / Mabile, Laurence / Cambon-Thomsen, Anne / Boucher, Pascal / Dagher, Georges / Hewitt, Robert / Parodi, Barbara / Hofman, Paul

    Biopreservation and biobanking

    2013  Volume 11, Issue 4, Page(s) 235–244

    Abstract: The number of biobanks, in particular hospital-integrated tumor biobanks (HITB), is increasing all around the world. This is the consequence of an increase in the need for human biological resources for scientific projects and more specifically, for ... ...

    Abstract The number of biobanks, in particular hospital-integrated tumor biobanks (HITB), is increasing all around the world. This is the consequence of an increase in the need for human biological resources for scientific projects and more specifically, for translational and clinical research. The robustness and reproducibility of the results obtained depend greatly on the quality of the biospecimens and the associated clinical data. They also depend on the number of patients studied and on the expertise of the biobank that supplied the biospecimens. The quality of a research biobank is undoubtedly reflected in the number and overall quality of the research projects conducted with biospecimens provided by the biobank. Since the quality of a research project can be measured from the impact factor of resulting publications, this also provides some indication of the quality of a research biobank. It is necessary for the biobank community to define "surrogate" quality indicators, and to establish systems of evaluation in relation to current and future resource requirements. These indicators will help in the realistic assessment of biobanks by institutions and funding bodies, and they will help biobanks demonstrate their value, raise their quality standards, and compete for funding. Given that biobanks are expensive structures to maintain, funding issues are particularly important, especially in the current economic climate. Use of performance indicators may also contribute to the development of a biobank impact factor or "bioresource research impact factor" (BRIF). Here we review four major categories of indicators that appear to be useful for the evaluation of a(m) HITB (quality, activity, scientific productivity, and "visibility"). In addition, we propose a scoring system to measure the chosen indicators.
    MeSH term(s) Hospitals ; Humans ; Journal Impact Factor ; Quality Control ; Tissue Banks/economics ; Tissue Banks/organization & administration ; Tissue Banks/standards ; Translational Medical Research
    Language English
    Publishing date 2013-08
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2593993-2
    ISSN 1947-5543 ; 1947-5535
    ISSN (online) 1947-5543
    ISSN 1947-5535
    DOI 10.1089/bio.2013.0015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: International network of cancer genome projects.

    Hudson, Thomas J / Anderson, Warwick / Artez, Axel / Barker, Anna D / Bell, Cindy / Bernabé, Rosa R / Bhan, M K / Calvo, Fabien / Eerola, Iiro / Gerhard, Daniela S / Guttmacher, Alan / Guyer, Mark / Hemsley, Fiona M / Jennings, Jennifer L / Kerr, David / Klatt, Peter / Kolar, Patrik / Kusada, Jun / Lane, David P /
    Laplace, Frank / Youyong, Lu / Nettekoven, Gerd / Ozenberger, Brad / Peterson, Jane / Rao, T S / Remacle, Jacques / Schafer, Alan J / Shibata, Tatsuhiro / Stratton, Michael R / Vockley, Joseph G / Watanabe, Koichi / Yang, Huanming / Yuen, Matthew M F / Knoppers, Bartha M / Bobrow, Martin / Cambon-Thomsen, Anne / Dressler, Lynn G / Dyke, Stephanie O M / Joly, Yann / Kato, Kazuto / Kennedy, Karen L / Nicolás, Pilar / Parker, Michael J / Rial-Sebbag, Emmanuelle / Romeo-Casabona, Carlos M / Shaw, Kenna M / Wallace, Susan / Wiesner, Georgia L / Zeps, Nikolajs / Lichter, Peter / Biankin, Andrew V / Chabannon, Christian / Chin, Lynda / Clément, Bruno / de Alava, Enrique / Degos, Françoise / Ferguson, Martin L / Geary, Peter / Hayes, D Neil / Johns, Amber L / Kasprzyk, Arek / Nakagawa, Hidewaki / Penny, Robert / Piris, Miguel A / Sarin, Rajiv / Scarpa, Aldo / van de Vijver, Marc / Futreal, P Andrew / Aburatani, Hiroyuki / Bayés, Mónica / Botwell, David D L / Campbell, Peter J / Estivill, Xavier / Grimmond, Sean M / Gut, Ivo / Hirst, Martin / López-Otín, Carlos / Majumder, Partha / Marra, Marco / McPherson, John D / Ning, Zemin / Puente, Xose S / Ruan, Yijun / Stunnenberg, Hendrik G / Swerdlow, Harold / Velculescu, Victor E / Wilson, Richard K / Xue, Hong H / Yang, Liu / Spellman, Paul T / Bader, Gary D / Boutros, Paul C / Flicek, Paul / Getz, Gad / Guigó, Roderic / Guo, Guangwu / Haussler, David / Heath, Simon / Hubbard, Tim J / Jiang, Tao / Jones, Steven M / Li, Qibin / López-Bigas, Nuria / Luo, Ruibang / Muthuswamy, Lakshmi / Ouellette, B F Francis / Pearson, John V / Quesada, Victor / Raphael, Benjamin J / Sander, Chris / Speed, Terence P / Stein, Lincoln D / Stuart, Joshua M / Teague, Jon W / Totoki, Yasushi / Tsunoda, Tatsuhiko / Valencia, Alfonso / Wheeler, David A / Wu, Honglong / Zhao, Shancen / Zhou, Guangyu / Lathrop, Mark / Thomas, Gilles / Yoshida, Teruhiko / Axton, Myles / Gunter, Chris / Miller, Linda J / Zhang, Junjun / Haider, Syed A / Wang, Jianxin / Yung, Christina K / Cros, Anthony / Cross, Anthony / Liang, Yong / Gnaneshan, Saravanamuttu / Guberman, Jonathan / Hsu, Jack / Chalmers, Don R C / Hasel, Karl W / Kaan, Terry S H / Lowrance, William W / Masui, Tohru / Rodriguez, Laura Lyman / Vergely, Catherine / Bowtell, David D L / Cloonan, Nicole / deFazio, Anna / Eshleman, James R / Etemadmoghadam, Dariush / Gardiner, Brooke B / Gardiner, Brooke A / Kench, James G / Sutherland, Robert L / Tempero, Margaret A / Waddell, Nicola J / Wilson, Peter J / Gallinger, Steve / Tsao, Ming-Sound / Shaw, Patricia A / Petersen, Gloria M / Mukhopadhyay, Debabrata / DePinho, Ronald A / Thayer, Sarah / Shazand, Kamran / Beck, Timothy / Sam, Michelle / Timms, Lee / Ballin, Vanessa / Lu, Youyong / Ji, Jiafu / Zhang, Xiuqing / Chen, Feng / Hu, Xueda / Yang, Qi / Tian, Geng / Zhang, Lianhai / Xing, Xiaofang / Li, Xianghong / Zhu, Zhenggang / Yu, Yingyan / Yu, Jun / Tost, Jörg / Brennan, Paul / Holcatova, Ivana / Zaridze, David / Brazma, Alvis / Egevard, Lars / Prokhortchouk, Egor / Banks, Rosamonde Elizabeth / Uhlén, Mathias / Viksna, Juris / Ponten, Fredrik / Skryabin, Konstantin / Birney, Ewan / Borg, Ake / Børresen-Dale, Anne-Lise / Caldas, Carlos / Foekens, John A / Martin, Sancha / Reis-Filho, Jorge S / Richardson, Andrea L / Sotiriou, Christos / Thoms, Giles / van't Veer, Laura / Birnbaum, Daniel / Blanche, Hélène / Boucher, Pascal / Boyault, Sandrine / Masson-Jacquemier, Jocelyne D / Pauporté, Iris / Pivot, Xavier / Vincent-Salomon, Anne / Tabone, Eric / Theillet, Charles / Treilleux, Isabelle / Bioulac-Sage, Paulette / Decaens, Thomas / Franco, Dominique / Gut, Marta / Samuel, Didier / Zucman-Rossi, Jessica / Eils, Roland / Brors, Benedikt / Korbel, Jan O / Korshunov, Andrey / Landgraf, Pablo / Lehrach, Hans / Pfister, Stefan / Radlwimmer, Bernhard / Reifenberger, Guido / Taylor, Michael D / von Kalle, Christof / Majumder, Partha P / Pederzoli, Paolo / Lawlor, Rita A / Delledonne, Massimo / Bardelli, Alberto / Gress, Thomas / Klimstra, David / Zamboni, Giuseppe / Nakamura, Yusuke / Miyano, Satoru / Fujimoto, Akihiro / Campo, Elias / de Sanjosé, Silvia / Montserrat, Emili / González-Díaz, Marcos / Jares, Pedro / Himmelbauer, Heinz / Himmelbaue, Heinz / Bea, Silvia / Aparicio, Samuel / Easton, Douglas F / Collins, Francis S / Compton, Carolyn C / Lander, Eric S / Burke, Wylie / Green, Anthony R / Hamilton, Stanley R / Kallioniemi, Olli P / Ley, Timothy J / Liu, Edison T / Wainwright, Brandon J

    Nature

    2010  Volume 464, Issue 7291, Page(s) 993–998

    Abstract: The International Cancer Genome Consortium (ICGC) was launched to coordinate large-scale cancer genome studies in tumours from 50 different cancer types and/or subtypes that are of clinical and societal importance across the globe. Systematic studies of ... ...

    Abstract The International Cancer Genome Consortium (ICGC) was launched to coordinate large-scale cancer genome studies in tumours from 50 different cancer types and/or subtypes that are of clinical and societal importance across the globe. Systematic studies of more than 25,000 cancer genomes at the genomic, epigenomic and transcriptomic levels will reveal the repertoire of oncogenic mutations, uncover traces of the mutagenic influences, define clinically relevant subtypes for prognosis and therapeutic management, and enable the development of new cancer therapies.
    MeSH term(s) DNA Methylation ; DNA Mutational Analysis/trends ; Databases, Genetic ; Genes, Neoplasm/genetics ; Genetics, Medical/organization & administration ; Genetics, Medical/trends ; Genome, Human/genetics ; Genomics/organization & administration ; Genomics/trends ; Humans ; Intellectual Property ; International Cooperation ; Mutation ; Neoplasms/classification ; Neoplasms/genetics ; Neoplasms/pathology ; Neoplasms/therapy
    Language English
    Publishing date 2010-02-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/nature08987
    Database MEDical Literature Analysis and Retrieval System OnLINE

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