Article ; Online: Implementation of a retinal stroke-code protocol results in visual recovery in patients receiving reperfusion therapies.
2024 , Page(s) 23969873231221366
Abstract: Introduction: Reperfusion therapies represent promising treatments for patients with Central Retinal Artery Occlusion (CRAO), but access is limited due to low incidence and lack of protocols. We aimed to describe the benefit of implementing a Retinal ... ...
| Abstract | Introduction: Reperfusion therapies represent promising treatments for patients with Central Retinal Artery Occlusion (CRAO), but access is limited due to low incidence and lack of protocols. We aimed to describe the benefit of implementing a Retinal Stroke-Code protocol regarding access to reperfusion, visual acuity and aetiological assessment. Patients and methods: Prospective cohort study performed at a Comprehensive Stroke Centre. Criteria for activation were sudden monocular, painless vision loss within 6 h from onset. Eligible patients received IAT when immediately available and IVT otherwise. All patients were followed by ophthalmologists to assess best-corrected visual acuity (BCVA) and visual complications, and by neurologists for aetiological workup. Visual amelioration was defined as improvement of at least one Early Treatment Diabetic Retinopathy Study (ETDRS) letter from baseline to 1 week. Results: Of 49 patients with CRAO, 15 (30.6%) received reperfusion therapies (12 IVT, 3 IAT). Presentation beyond 6 h was the main contraindication. Patients receiving reperfusion therapies had better rates of visual improvement (33.3% vs 5.9%, Conclusion: A comprehensive acute management of CRAO is feasible despite low incidence. In our study, reperfusion therapies were safe and associated with higher rates of visual recovery. A similar etiological workup than ischemic stroke led to of high proportion of underlying aetiologies. |
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| Language | English |
| Publishing date | 2024-01-08 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 2851287-X |
| ISSN | 2396-9881 ; 2396-9873 |
| ISSN (online) | 2396-9881 |
| ISSN | 2396-9873 |
| DOI | 10.1177/23969873231221366 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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