LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 7 of total 7

Search options

  1. Article ; Online: Mathematical modeling of mpox

    Jeta Molla / Idriss Sekkak / Ariel Mundo Ortiz / Iain Moyles / Bouchra Nasri

    One Health, Vol 16, Iss , Pp 100540- (2023)

    A scoping review

    2023  

    Abstract: Background: Mpox (monkeypox), a disease historically endemic to Africa, has seen its largest outbreak in 2022 by spreading to many regions of the world and has become a public health threat. Informed policies aimed at controlling and managing the spread ... ...

    Abstract Background: Mpox (monkeypox), a disease historically endemic to Africa, has seen its largest outbreak in 2022 by spreading to many regions of the world and has become a public health threat. Informed policies aimed at controlling and managing the spread of this disease necessitate the use of adequate mathematical modeling strategies. Objective: In this scoping review, we sought to identify the mathematical models that have been used to study mpox transmission in the literature in order to determine what are the model classes most frequently used, their assumptions, and the modelling gaps that need to be addressed in the context of the epidemiological characteristics of the ongoing mpox outbreak. Methods: This study employed the methodology of the PRISMA guidelines for scoping reviews to identify the mathematical models available to study mpox transmission dynamics. Three databases (PubMed, Web of Science and MathSciNet) were systematically searched to identify relevant studies. Results: A total of 5827 papers were screened from the database queries. After the screening, 35 studies that met the inclusion criteria were analyzed, and 19 were finally included in the scoping review. Our results show that compartmental, branching process, Monte Carlo (stochastic), agent-based, and network models have been used to study mpox transmission dynamics between humans as well as between humans and animals. Furthermore, compartmental and branching models have been the most commonly used classes. Conclusions: There is a need to develop modeling strategies for mpox transmission that take into account the conditions of the current outbreak, which has been largely driven by human-to-human transmission in urban settings. In the current scenario, the assumptions and parameters used by most of the studies included in this review (which are largely based on a limited number of studies carried out in Africa in the early 80s) may not be applicable, and therefore, can complicate any public health policies that are derived from their ...
    Keywords Monkeypox ; Mpox ; Mathematical modelling ; Scoping review ; Medicine (General) ; R5-920
    Subject code 910
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Modelling the transmission of dengue, zika and chikungunya

    Kamal Raj Acharya / Jhoana P Romero-Leiton / Bouchra Nasri / Jane Elizabeth Parmley / Julien Arino

    BMJ Open, Vol 13, Iss

    a scoping review protocol

    2023  Volume 9

    Abstract: Introduction Aedes mosquitoes are the primary vectors for the spread of viruses like dengue (DENV), zika (ZIKV) and chikungunya (CHIKV), all of which affect humans. Those diseases contribute to global public health issues because of their great ... ...

    Abstract Introduction Aedes mosquitoes are the primary vectors for the spread of viruses like dengue (DENV), zika (ZIKV) and chikungunya (CHIKV), all of which affect humans. Those diseases contribute to global public health issues because of their great dispersion in rural and urban areas. Mathematical and statistical models have become helpful in understanding these diseases’ epidemiological dynamics. However, modelling the complexity of a real phenomenon, such as a viral disease, should consider several factors. This scoping review aims to document, identify and classify the most important factors as well as the modelling strategies for the spread of DENV, ZIKV and CHIKV.Methods and analysis We will conduct searches in electronic bibliographic databases such as PubMed, MathSciNet and the Web of Science for full-text peer-reviewed articles written in English, French and Spanish. These articles should use mathematical and statistical modelling frameworks to study dengue, zika and chikungunya, and their cocirculation/coinfection with other diseases, with a publication date between 1 January 2011 and 31 July 2023. Eligible studies should employ deterministic, stochastic or statistical modelling approaches, consider control measures and incorporate parameters’ estimation or considering calibration/validation approaches. We will exclude articles focusing on clinical/laboratory experiments or theoretical articles that do not include any case study. Two reviewers specialised in zoonotic diseases and mathematical/statistical modelling will independently screen and retain relevant studies. Data extraction will be performed using a structured form, and the findings of the study will be summarised through classification and descriptive analysis. Three scoping reviews will be published, each focusing on one disease and its cocirculation/co-infection with other diseases.Ethics and dissemination This protocol is exempt from ethics approval because it is carried out on published manuscripts and without the participation of humans ...
    Keywords Medicine ; R
    Subject code 306
    Language English
    Publishing date 2023-09-01T00:00:00Z
    Publisher BMJ Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: How is the COVID-19 pandemic impacting our life, mental health, and well-being? Design and preliminary findings of the pan-Canadian longitudinal COHESION study

    Stephan Gabet / Benoit Thierry / Rania Wasfi / Guido Simonelli / Catherine Hudon / Lily Lessard / Ève Dubé / Bouchra Nasri / Yan Kestens / Grégory Moullec

    BMC Public Health, Vol 23, Iss 1, Pp 1-

    2023  Volume 20

    Abstract: Abstract Background With the advent of the COVID-19 pandemic, in-person social interactions and opportunities for accessing resources that sustain health and well-being have drastically reduced. We therefore designed the pan-Canadian prospective COVID-19: ...

    Abstract Abstract Background With the advent of the COVID-19 pandemic, in-person social interactions and opportunities for accessing resources that sustain health and well-being have drastically reduced. We therefore designed the pan-Canadian prospective COVID-19: HEalth and Social Inequities across Neighbourhoods (COHESION) cohort to provide a deeper understanding of how the COVID-19 pandemic context affects mental health and well-being, key determinants of health, and health inequities. Methods This paper presents the design of the two-phase COHESION Study, and descriptive results from the first phase conducted between May 2020 and September 2021. During that period, the COHESION research platform collected monthly data linked to COVID-19 such as infection and vaccination status, perceptions and attitudes regarding pandemic-related measures, and information on participants’ physical and mental health, well-being, sleep, loneliness, resilience, substances use, living conditions, social interactions, activities, and mobility. Results The 1,268 people enrolled in the Phase 1 COHESION Study are for the most part from Ontario (47%) and Quebec (33%), aged 48 ± 16 years [mean ± standard deviation (SD)], and mainly women (78%), White (85%), with a university degree (63%), and living in large urban centers (70%). According to the 298 ± 68 (mean ± SD) prospective questionnaires completed each month on average, the first year of follow-up reveals significant temporal variations in standardized indexes of well-being, loneliness, anxiety, depression, and psychological distress. Conclusions The COHESION Study will allow identifying trajectories of mental health and well-being while investigating their determinants and how these may vary by subgroup, over time, and across different provinces in Canada, in varying context including the pandemic recovery period. Our findings will contribute valuable insights to the urban health field and inform future public health interventions.
    Keywords COVID-19 ; Mental health ; Prospective cohort ; Social interactions ; Study design ; Well-being ; Public aspects of medicine ; RA1-1270
    Subject code 360
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: School and community reopening during the COVID-19 pandemic

    Pei Yuan / Elena Aruffo / Evgenia Gatov / Yi Tan / Qi Li / Nick Ogden / Sarah Collier / Bouchra Nasri / Iain Moyles / Huaiping Zhu

    Royal Society Open Science, Vol 9, Iss

    a mathematical modelling study

    2022  Volume 2

    Abstract: Operating schools safely during the COVID-19 pandemic requires a balance between health risks and the need for in-person learning. Using demographic and epidemiological data between 31 July and 23 November 2020 from Toronto, Canada, we developed a ... ...

    Abstract Operating schools safely during the COVID-19 pandemic requires a balance between health risks and the need for in-person learning. Using demographic and epidemiological data between 31 July and 23 November 2020 from Toronto, Canada, we developed a compartmental transmission model with age, household and setting structure to study the impact of schools reopening in September 2020. The model simulates transmission in the home, community and schools, accounting for differences in infectiousness between adults and children, and accounting for work-from-home and virtual learning. While we found a slight increase in infections among adults (2.2%) and children (4.5%) within the first eight weeks of school reopening, transmission in schools was not the key driver of the virus resurgence in autumn 2020. Rather, it was community spread that determined the outbreak trajectory, primarily due to increases in contact rates among adults in the community after school reopening. Analyses of cross-infection among households, communities and schools revealed that home transmission is crucial for epidemic progression and safely operating schools, while the degree of in-person attendance has a larger impact than other control measures in schools. This study suggests that safe school reopening requires the strict maintenance of public health measures in the community.
    Keywords COVID-19 ; school reopening ; community opening ; transmission model ; household structure ; age structure ; Science ; Q
    Subject code 370
    Language English
    Publishing date 2022-02-01T00:00:00Z
    Publisher The Royal Society
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article ; Online: Bayesian Estimation for GEV-B-Spline Model

    Bouchra Nasri / Salaheddine El Adlouni / Taha B. M. J. Ouarda

    Open Journal of Statistics, Vol 03, Iss 02, Pp 118-

    2013  Volume 128

    Abstract: The stationarity hypothesis is essential in hydrological frequency analysis and statistical inference. This assumption is often not fulfilled for large observed datasets, especially in the case of hydro-climatic variables. The Generalized Ex treme Value ... ...

    Abstract The stationarity hypothesis is essential in hydrological frequency analysis and statistical inference. This assumption is often not fulfilled for large observed datasets, especially in the case of hydro-climatic variables. The Generalized Ex treme Value distribution with covariates allows to model data in the presence of non-stationarity and/or dependence on covariates. Linear and non-linear dependence structures have been proposed with the corresponding fitting approach. The objective of the present study is to develop the GEV model with B-Spline in a Bayesian framework. A Markov Chain Monte Carlo (MCMC) algorithm has been developed to estimate quantiles and their posterior distributions. The methods are tested and illustrated using simulated data and applied to meteorological data. Results indicate the better performance of the proposed Bayesian method for rainfall quantile estimation according to BIAS and RMSE criteria especially for high return period events.
    Keywords GEV ; Bayesien ; B-Spline ; Nonlinearity ; Covariate ; Non-Stationarity ; Probabilities. Mathematical statistics ; QA273-280 ; Mathematics ; QA1-939 ; Science ; Q ; DOAJ:Statistics ; DOAJ:Mathematics and Statistics
    Subject code 310
    Language English
    Publishing date 2013-04-01T00:00:00Z
    Publisher Scientific Research Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article ; Online: School and community reopening during the COVID-19 pandemic: a mathematical modeling study

    Yuan, Pei / Aruffo, Elena / ogden, Nicholas / Tan, Yi / Gatov, Evgenia / Gournis, Effie / Collier, Sarah / Li, Qi / Moyles, Iain / Bouchra, Nasri / Zhu, Huaiping

    medRxiv

    Abstract: Background The closure of communities, including schools, has been adopted to control the coronavirus disease 2019 (COVID-19) epidemic in most countries. Operating schools safely during the pandemic requires a balance between health risks and the need ... ...

    Abstract Background The closure of communities, including schools, has been adopted to control the coronavirus disease 2019 (COVID-19) epidemic in most countries. Operating schools safely during the pandemic requires a balance between health risks and the need for in-person learning. We use compartmental models to explore school reopening scenarios. Methods Using demographic and epidemiological data between July 31 and November 23, 2020 from the city of Toronto, we developed a Susceptible-Exposed-Asymptomatic-Infectious-Recovered-Hospitalized-Isolated model. Our model with age, household, and community transmission allow us to study the impact of schools open in September 2020. The model mimics the transmission in households, the community, and schools, accounting for differences in infectiousness between adults and children and youth and adults9 working status. We assessed the extent to which school opening may have contributed to COVID-19 resurgence in the fall and simulated scenarios for the safe reopening of schools up to May 31, 2021. We further considered the impact of the introduction of the new variant of concern. Findings Though a slight increase in infections among adults (2.8%) and children (5.4%) is anticipated by the end of the year, safe school opening is possible with stringent nonpharmaceutical interventions (NPIs) decreasing the risk of transmission in the community and the household. We found that while school reopening was not the key driver in virus resurgence, but rather it was community spread that determined the outbreak trajectory, brief school closures did reduce infections when transmission risk within the home was low. When considered possible cross-infection amongst households, communities, and schools, we found that home transmission was crucial for mitigating the epidemic and safely operating schools. Simulating the introduction of a new strain with higher infectiousness, we observed substantial increases in infections, even when both schools and communities are closed. Interpretation Schools can open safely under strict maintenance of strict public health measures in the community. The gradual opening of schools and communities can only be achieved by maintaining NPIs and mitigating household transmission risk to avoid the broader escape of infections acquired in schools into the community via households. If the new COVID-19 strain is more infectious for children, public spaces, including schools, should be closed, and additional NPIs, including the use of masks, should be extended to toddlers.
    Keywords covid19
    Language English
    Publishing date 2021-01-15
    Publisher Cold Spring Harbor Laboratory Press
    Document type Article ; Online
    DOI 10.1101/2021.01.13.21249753
    Database COVID19

    Full text online

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article: Organic and inorganic contamination impacts on metabolic capacities in American and European yellow eels

    Caron, Antoine / Bouchra Nasri / Fabien Pierron / Hélène Budzinski / Magalie Baudrimont / Maikel Rosabal / Mathilde Lauzent / Patrice Couture / Pauline Pannetier / Pierre Labadie

    Canadian journal of fisheries and aquatic sciences. 2016 May 3, v. 73, no. 10

    2016  

    Abstract: American (Anguilla rostrata) and European (Anguilla anguilla) eel populations are declining since the 1980s, and contamination is thought to play a role. To determine the influence of organic (organochlorinated pesticides (OCPs), polybrominated diphenyl ... ...

    Abstract American (Anguilla rostrata) and European (Anguilla anguilla) eel populations are declining since the 1980s, and contamination is thought to play a role. To determine the influence of organic (organochlorinated pesticides (OCPs), polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs)) and inorganic (Zn, As, Cd, Cu, Pb, Cr, Ni, Ag, Se, Hg) contaminants on wild yellow eels liver and muscle metabolic capacities, enzymatic assays were performed. In A. rostrata liver, G6PDH moderate negative correlations with Ag, Pb, and As suggest impacts on lipid metabolism, and correlations between Cd and age (positive) and between Cd and relative condition factor (Kₙ; negative) indicate impacts on older eels health. Anguilla anguilla liver proteins, pyruvate kinase (PK), and lactate dehydrogenase (LDH) were positively linked to Zn, Pb, and Cu, suggesting effects on glycolytic and anaerobic capacities. In A. anguilla muscle, absence of correlation between age and lipids plus strong positive correlations between age and OCPs, PBDEs, PCBs, and Hg suggest lipid storage impairment in older contaminated eels. Overall, our study indicates contamination impacts on both species’ metabolic capacities, but the broader range of contaminants found in A. anguilla brings greater impacts compared with A. rostrata.
    Keywords Anguilla anguilla ; Anguilla rostrata ; arsenic ; biochemical pathways ; cadmium ; chromium ; condition factor ; copper ; eel ; glucose-6-phosphate 1-dehydrogenase ; glycolysis ; lactate dehydrogenase ; lead ; lipid metabolism ; lipids ; liver ; mercury ; muscles ; nickel ; pesticides ; polybrominated diphenyl ethers ; polychlorinated biphenyls ; pyruvate kinase ; selenium ; silver ; zinc
    Language English
    Dates of publication 2016-0503
    Size p. 1557-1566.
    Publishing place NRC Research Press
    Document type Article
    ZDB-ID 1473089-3
    ISSN 1205-7533 ; 0706-652X
    ISSN (online) 1205-7533
    ISSN 0706-652X
    DOI 10.1139/cjfas-2015-0473
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top