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  1. Article: Chirurgie ambulatoire de l’hypospade pénien pédiatrique : expérience monocentrique avec un recul moyen de 3 ans.

    Izérable, Baptiste / Boudaoud, Nadia / Poli-Merol, Marie-Laurence / Pons, Maguelonne / Léon, Priscilla

    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie

    2023  Volume 33, Issue 10, Page(s) 474–480

    Title translation Outpatient surgery for penile hypospadias in pediatric urology: A monocentric experience with a mean follow-up of 3 years.
    MeSH term(s) Child ; Humans ; Infant ; Male ; Ambulatory Surgical Procedures ; Follow-Up Studies ; Hypospadias/surgery ; Retrospective Studies ; Treatment Outcome ; Urologic Surgical Procedures, Male/methods ; Urology
    Language French
    Publishing date 2023-07-27
    Publishing country France
    Document type English Abstract ; Journal Article ; Observational Study
    ZDB-ID 1186190-3
    ISSN 1166-7087
    ISSN 1166-7087
    DOI 10.1016/j.purol.2023.07.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3959: Show issues Location:
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  2. Article ; Online: Case reports of large and symptomatic abdominal tumors in newborns: Pitfalls, difficulties in management, and surgical decision making.

    Laconi, Francesco / Bischoff, Charline / Michelet, Daphne / Loron, Gauthier / Bednarek, Nathalie / Poli-Merol, Marie-Laurence / Pons, Maguelonne / Boudaoud, Nadia

    Cancer reports (Hoboken, N.J.)

    2022  Volume 5, Issue 11, Page(s) e1726

    Abstract: Background: Large and rapidly growing abdominal tumors may result in fatal outcomes in newborns. In some cases, a rapidly worsening clinical condition requires surgical decision-making despite the absence of a precise histological diagnosis. In these ... ...

    Abstract Background: Large and rapidly growing abdominal tumors may result in fatal outcomes in newborns. In some cases, a rapidly worsening clinical condition requires surgical decision-making despite the absence of a precise histological diagnosis. In these situations, there is neither a guide nor consensus.
    Case: We highlight our experience with five patients with large abdominal tumors and assess the available literature for the best possible management of a rare condition.
    Conclusion: In these cases, laparostomy should be considered as a life-saving procedure. If the liver is involved and coagulopathy is present, prognosis is often compromised.
    MeSH term(s) Humans ; Infant, Newborn ; Abdominal Neoplasms/diagnosis ; Abdominal Neoplasms/surgery ; Prognosis ; Decision Making
    Language English
    Publishing date 2022-10-04
    Publishing country United States
    Document type Case Reports
    ISSN 2573-8348
    ISSN (online) 2573-8348
    DOI 10.1002/cnr2.1726
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Financial and relational impact of having a boy with posterior urethral valves.

    Harper, Luke / Botto, Nathalie / Peycelon, Matthieu / Michel, Jean-Luc / Leclair, Marc-David / Garnier, Sarah / Clermidi, Pauline / Arnaud, Alexis / Dariel, Anne / Dobremez, Eric / Faure, Alice / Fourcade, Laurent / Boudaoud, Nadia / Chaussy, Yann / Huiart, Laetitia / Bocquet, Valery / Ferdynus, Cyril / Sauvat, Frédérique

    Frontiers in pediatrics

    2023  Volume 11, Page(s) 1228248

    Abstract: Introduction: Childhood chronic diseases affect family functioning and well-being. The aim of this study was to measure the impact of caring for a child with PUV, and the factors that most impact the burden of care.: Patients and method: We gave a ... ...

    Abstract Introduction: Childhood chronic diseases affect family functioning and well-being. The aim of this study was to measure the impact of caring for a child with PUV, and the factors that most impact the burden of care.
    Patients and method: We gave a questionnaire on the familial impact of having a child with posterior urethral valves to all parents of a child included in the CIRCUP trial from 2015 onwards. The questionnaire included questions about the parents' demographics, health, professional, financial and marital status and how these evolved since the child's birth as well as the "impact on family scale" (IOFS), which gives a total score ranging from 15 (no impact) to 60 (maximum impact). We then analyzed both the results of the specific demographic questions as well as the factors which influenced the IOFS score.
    Results: We retrieved answers for 38/51 families (74.5% response rate). The average IOFS score was 23.7 (15-51). We observed that the child's creatinine level had an effect on the IOFS score (
    Conclusion: In conclusion, having a boy with PUV significantly impacts families. The risk of parental separation and decrease in revenue is significant. Strategies aiming to decrease these factors should be put in place as soon as possible.
    Language English
    Publishing date 2023-08-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2023.1228248
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Risk factors for febrile urinary tract infection in boys with posterior urethral valves.

    Harper, Luke / Botto, Nathalie / Peycelon, Matthieu / Michel, Jean-Luc / Leclair, Marc-David / Garnier, Sarah / Clermidi, Pauline / Arnaud, Alexis P / Dariel, Anne-Laure / Dobremez, Eric / Faure, Alice / Fourcade, Laurent / Boudaoud, Nadia / Chaussy, Yann / Collin, Fideline / Huiart, Laetitia / Ferdynus, Cyril / Bocquet, Valery / Sauvat, Frederique

    Frontiers in pediatrics

    2022  Volume 10, Page(s) 971662

    Abstract: Objective: Boys with posterior urethral valves (PUV) present an increased risk of febrile urinary tract infection (fUTI). Identifying specific risk factors could allow for tailoring UTI prevention. The aim of this study was to use the data from the ... ...

    Abstract Objective: Boys with posterior urethral valves (PUV) present an increased risk of febrile urinary tract infection (fUTI). Identifying specific risk factors could allow for tailoring UTI prevention. The aim of this study was to use the data from the CIRCUP randomized controlled trial data to identify patient characteristics associated with a higher risk of fUTI.
    Patients and methods: We performed a secondary analysis of the data from the CIRCUP randomized trial which included boys with PUV, randomized to circumcision and antibiotic prophylaxis vs. antibiotic prophylaxis alone and followed for 2 years. There was only 1 episode of fUTI in the circumcision group vs. 17 in the uncircumcised group. We therefore only studied the antibiotic prophylaxis alone group and compared age at prenatal diagnosis, size and weight at birth, presence of dilating VUR at diagnosis, abnormal DMSA scan at 2 months, and nadir creatinine between children who presented a fUTI and those who did not, as well as age at first episode of fUTI.
    Results: The study group consisted of 42 patients of which 17 presented at least on fUTI. Presence of dilating VUR was significantly associated with risk of fUTI (
    Conclusion: In boys with PUV, presence of high-grade VUR is associated with a higher risk of presenting a fUTI. The rate of febrile UTIs seems to decrease after 9 months.
    Language English
    Publishing date 2022-09-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2022.971662
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  5. Article ; Online: Management of refractory overactive bladder in children by transcutaneous posterior tibial nerve stimulation: A controlled study.

    Boudaoud, Nadia / Binet, Aurélien / Line, Antoine / Chaouadi, Dalila / Jolly, Catherine / Fiquet, Caroline Francois / Ripert, Thomas / Merol, Marie Laurence Poli

    Journal of pediatric urology

    2015  Volume 11, Issue 3, Page(s) 138.e1–10

    Abstract: Objective: To assess the objective efficacy of transcutaneous posterior tibial nerve stimulation in children presenting with overactive bladder resistant to well conducted treatment.: Material and method: This was a randomized, double-blind, ... ...

    Abstract Objective: To assess the objective efficacy of transcutaneous posterior tibial nerve stimulation in children presenting with overactive bladder resistant to well conducted treatment.
    Material and method: This was a randomized, double-blind, controlled study on 20 children with OAB. All patients were previously treated with anticholinergic drugs associated with detrusor rehabilitation, diet advice, bladder-voiding hygiene and constipation treatment, with poor clinical results. Patients were randomized into two groups: -Group A: treatment with PTNS (n = 11). -Group B: sham treatment (n = 9). The program lasted 12 consecutive weeks with two 30-minutes sessions a week. Each patient underwent pre-stimulation urodynamic testing to validate bladder overactivity followed by a post-stimulation testing. Pre- and post-stimulation urodynamic parameters were compared in order to objectively evaluate the treatment's efficacy. The patients noted their incontinence episodes for 7 consecutive days in a diary before the beginning of the program, in the middle and at the end of it: this led to computing an incontinence score (score ranged from 0 to 13, from good to poor). The difference between the pre-stimulation and post-stimulation score enabled to express clinical results in terms of poor (less than a 3-point decrease), medium (a 3 to 5-point decrease), good (6 to 8-point decrease), very good (final score ranged between 0 and 3). Children were questioned regarding their impression of being stimulated or not.
    Results: In Group A, there were five very good clinical results (45%), one medium (10%) and five poor results (45%). In group B, nine very good results (66%) and three poor results (33%) were noted. Regarding urodynamic testing, volume voided during urgency (184 mL to 265 mL), maximal cystomanometry volume (215 mL to 274 mL) and volume at the onset of the first overactive detrusor contraction (ODC) (48 mL to 174 mL) were significantly increased in Group A (p = 0.002, p = 0.024 and p = 0.001) and maximal bladder pressure during ODC had decreased (61 to 46) (p = 0.042). 85% children in group A thought they were being stimulated vs. 70% in group B.
    Conclusion: Even though we noticed urodynamics improvements in group A, which objectively supports the efficacy of TCTPNS, clinical results remained the same between the two groups. In spite of the small size of our sample, this underlines the placebo effect of any type management in this pediatric population. Studying precisely the maximal useful voltage and duration of stimulation should then be relevant in order to yield maximal benefits from this easy-to-use procedure.
    MeSH term(s) Child ; Cholinergic Antagonists/therapeutic use ; Double-Blind Method ; Female ; Humans ; Male ; Retreatment ; Tibial Nerve ; Transcutaneous Electric Nerve Stimulation ; Treatment Outcome ; Urinary Bladder, Overactive/diagnosis ; Urinary Bladder, Overactive/etiology ; Urinary Bladder, Overactive/therapy ; Urodynamics
    Chemical Substances Cholinergic Antagonists
    Language English
    Publishing date 2015-06
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2237683-5
    ISSN 1873-4898 ; 1477-5131
    ISSN (online) 1873-4898
    ISSN 1477-5131
    DOI 10.1016/j.jpurol.2014.09.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6387: Show issues Location:
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  6. Article ; Online: Esophageal Atresia and Respiratory Morbidity.

    Lejeune, Stéphanie / Sfeir, Rony / Rousseau, Véronique / Bonnard, Arnaud / Gelas, Thomas / Aumar, Madeleine / Panait, Nicoleta / Rabattu, Pierre-Yves / Irtan, Sabine / Fouquet, Virginie / Le Mandat, Aurélie / Cocci, Stephan De Napoli / Habonimana, Edouard / Lamireau, Thierry / Lemelle, Jean-Louis / Elbaz, Frédéric / Talon, Isabelle / Boudaoud, Nadia / Allal, Hossein /
    Buisson, Philippe / Petit, Thierry / Sapin, Emmanuel / Lardy, Hubert / Schmitt, Françoise / Levard, Guillaume / Scalabre, Aurélien / Michel, Jean-Luc / Jaby, Olivier / Pelatan, Cécile / De Vries, Philine / Borderon, Corinne / Fourcade, Laurent / Breaud, Jean / Arnould, Myriam / Tolg, Cécilia / Chaussy, Yann / Geiss, Stephan / Laplace, Christophe / Drumez, Elodie / El Mourad, Sawsan / Thumerelle, Caroline / Gottrand, Frédéric

    Pediatrics

    2021  Volume 148, Issue 3

    Abstract: Background and objectives: Respiratory diseases are common in children with esophageal atresia (EA), leading to increased morbidity and mortality in the first year. The primary study objective was to identify the factors associated with readmissions for ...

    Abstract Background and objectives: Respiratory diseases are common in children with esophageal atresia (EA), leading to increased morbidity and mortality in the first year. The primary study objective was to identify the factors associated with readmissions for respiratory causes in the first year in EA children.
    Methods: A population-based study. We included all children born between 2008 and 2016 with available data and analyzed factors at birth and 1 year follow-up. Factors with a
    Results: Among 1460 patients born with EA, 97 (7%) were deceased before the age of 1 year, and follow-up data were available for 1287 patients, who constituted our study population. EAs were Ladd classification type III or IV in 89%, preterm birth was observed in 38%, and associated malformations were observed in 52%. Collectively, 61% were readmitted after initial discharge in the first year, 31% for a respiratory cause. Among these, respiratory infections occurred in 64%, and 35% received a respiratory treatment. In logistic regression models, factors associated with readmission for a respiratory cause were recurrence of tracheoesophageal fistula, aortopexy, antireflux surgery, and tube feeding; factors associated with respiratory treatment were male sex and laryngeal cleft.
    Conclusions: Respiratory morbidity in the first year after EA repair is frequent, accounting for >50% of readmissions. Identifying high risk groups of EA patients (ie, those with chronic aspiration, anomalies of the respiratory tract, and need for tube feeding) may guide follow-up strategies.
    MeSH term(s) Cohort Studies ; Congenital Abnormalities/epidemiology ; Enteral Nutrition ; Esophageal Atresia/epidemiology ; Female ; Follow-Up Studies ; France/epidemiology ; Gastroesophageal Reflux/epidemiology ; Humans ; Infant ; Infant, Small for Gestational Age ; Male ; Patient Readmission/statistics & numerical data ; Premature Birth ; Registries ; Respiration Disorders/epidemiology ; Tracheoesophageal Fistula/epidemiology
    Language English
    Publishing date 2021-08-19
    Publishing country United States
    Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 207677-9
    ISSN 1098-4275 ; 0031-4005
    ISSN (online) 1098-4275
    ISSN 0031-4005
    DOI 10.1542/peds.2020-049778
    Database MEDical Literature Analysis and Retrieval System OnLINE

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