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  1. Article ; Online: Thrombocytopenic thrombotic purpura related to COVID-19 vaccine: apropos of 4 cases.

    Dos Santos, Célia / Castera, Santiago / Fernandez, José / Rosales, Julieta Soledad / Crescitelli, Franco / Boughen, Santiago / Iastrebner, Marcelo / Guerrero, Osvaldo / Amell Menco, Carlos / Gomez, Mariela / Gonzalez, Jacqueline / Alberto, Maria Fabiana / Sanchez-Luceros, Analía

    Hematology, transfusion and cell therapy

    2023  

    Language English
    Publishing date 2023-12-30
    Publishing country Brazil
    Document type Case Reports
    ISSN 2531-1387
    ISSN (online) 2531-1387
    DOI 10.1016/j.htct.2023.11.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Diarrea aguda en trasplantes renales y reno-pancreáticos.

    Carena, Alberto A / Boughen, Santiago / Gagliardi, María Inés / Galante, Mariana

    Medicina

    2015  Volume 75, Issue 1, Page(s) 29–36

    Abstract: Diarrhea is a frequent and potentially severe complication of kidney transplantation. We describe here, in a cross-sectional study, the epidemiological and microbiological characteristics of acute and persistent diarrhea in 52 inpatients with kidney and ... ...

    Title translation Acute diarrhea after kidney or kidney-pancreas transplantation.
    Abstract Diarrhea is a frequent and potentially severe complication of kidney transplantation. We describe here, in a cross-sectional study, the epidemiological and microbiological characteristics of acute and persistent diarrhea in 52 inpatients with kidney and kidney-pancreas transplant in a hospital in Buenos Aires, 42 (80.8%) of whom had received a kidney and 10 (19.2%) a kidney-pancreas transplant. Diarrhea was the reason of admission of 34 cases (65.4%). The etiology could be studied in 50 patients: 25 (50%) had no etiological diagnosis of diarrhea and 18 (36%) had a specific infectious etiology: 3 (6%) cytomegalovirus disease, 6 (12%) diarrhea attributed to cytomegalovirus, 5 (10%) to rotavirus and 4 (8%) to Clostridium difficile. In 7 (14%) diarrhea was attributed to drugs (mycophenolate mofetil and sirolimus). Patients with infectious diarrhea had recently received high doses of immunosuppressive therapy more frequently than the rest (p = 0.048). Those with diarrhea attributed to drugs were more frequently on mycophenolate mofetil than the rest (p = 0.039). Empirical modification of the immunosuppressive treatment was done in 16 (30.8%) and empirical antibiotic therapy was given to 47 patients (90.4%). Median length of hospital stay was 6 days. Seven patients (14.6%) persisted with diarrhea at the fifth day of admission. At hospital discharge all cases had complete resolution of symptoms and one third persisted with kidney failure. Information provided in this study can be useful as a starting point for improving preventive, diagnostic and therapeutic measures in these patients.
    MeSH term(s) Adult ; Clostridium Infections/complications ; Clostridium difficile/isolation & purification ; Cross-Sectional Studies ; Cytomegalovirus Infections/complications ; Diarrhea/etiology ; Female ; Humans ; Immunosuppressive Agents/adverse effects ; Kidney Transplantation/adverse effects ; Length of Stay/statistics & numerical data ; Male ; Middle Aged ; Pancreas Transplantation/adverse effects ; Rotavirus Infections/complications
    Chemical Substances Immunosuppressive Agents
    Language Spanish
    Publishing date 2015
    Publishing country Argentina
    Document type English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 411586-7
    ISSN 1669-9106 ; 0025-7680 ; 0325-951X
    ISSN (online) 1669-9106
    ISSN 0025-7680 ; 0325-951X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 163: Show issues Location:
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  3. Article: Enfermedad respiratoria grave en terapia intensiva durante la pandemia por el virus de influenza A (H1N1) 2009.

    Aquino-Esperanza, José / Rodríguez, Pablo O / Boughen, Santiago / Raimondi, Alejandro / Attie, Shiry / Maskin, Patricio / Bonelli, Ignacio / Valentini, Ricardo

    Medicina

    2010  Volume 70, Issue 5, Page(s) 401–407

    Abstract: We describe characteristics of patients admitted to our intensive care unit with severe acute respiratory illness and influenza-like syndrome during the first months of the pandemic influenza A(H1N1) 2009 in Argentina. We analyzed clinical data, severity ...

    Title translation Severe respiratory disease in an intensive care unit during influenza A(H1N1) 2009 pandemia.
    Abstract We describe characteristics of patients admitted to our intensive care unit with severe acute respiratory illness and influenza-like syndrome during the first months of the pandemic influenza A(H1N1) 2009 in Argentina. We analyzed clinical data, severity scores, laboratory tests, microbiological and radiological findings at admission, clinical outcomes and in-hospital mortality. H1N1 was confirmed by RT-PCR. Data from positive and negative PCR patients were compared. We admitted 31 adult patients between June and July 2009; median age: 54 years (IQR 33-66). A 54% (17) had positive PCR; 16 patients presented underlying medical conditions. Bilateral interstitial opacities were observed in chest radiography in 20 cases; 5 had unilateral lobar consolidation. Bacterial co-infection (isolation or IgM antibodies for bacterial infections) was found in 21 patients. Mechanical ventilation was required in 23 patients and 18 developed ARDS. Lymphopenia and increased creatine kinase levels were frequently observed (83% and 65% among PCR+ and PCR- respectively). Six patients died (19%); they were all over 75 years old, had cancer or immune-suppression. Early antiviral treatment (≤ 48 hours from symptoms onset) was associated with less frequency of mechanical ventilation (54% vs. 89%, p: 0.043). There were no differences in analyzed variables when comparing H1N1 positive and H1N1 negative patients; which suggests this approach as a most correct in future epidemic outbreaks. H1N1 infection was associated with severe respiratory illness and ARDS. Fatal outcome was observed in very old patients, or in those with major co-morbidities.
    MeSH term(s) Adult ; Aged ; Argentina/epidemiology ; Hospital Mortality ; Humans ; Influenza A Virus, H1N1 Subtype/isolation & purification ; Influenza, Human/complications ; Influenza, Human/epidemiology ; Influenza, Human/mortality ; Intensive Care Units/statistics & numerical data ; Middle Aged ; Pandemics/statistics & numerical data ; Respiratory Tract Diseases/mortality ; Respiratory Tract Diseases/therapy ; Respiratory Tract Diseases/virology ; Reverse Transcriptase Polymerase Chain Reaction ; Time Factors
    Language Spanish
    Publishing date 2010
    Publishing country Argentina
    Document type English Abstract ; Journal Article
    ZDB-ID 411586-7
    ISSN 1669-9106 ; 0025-7680 ; 0325-951X
    ISSN (online) 1669-9106
    ISSN 0025-7680 ; 0325-951X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 163: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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