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  1. Article: Mentha rotundifolia

    Boualam, Khadija / Bouhaddou, Nezha / Sobeh, Mansour / Tabyaoui, Mohamed / Taghzouti, Khalid

    Frontiers in neuroscience

    2023  Volume 17, Page(s) 1121029

    Abstract: Introduction: Oxidative stress plays a causal role in neurodegenerative diseases. The aim of this study is to evaluate the antioxidant and neuroprotective effects of : Methods: The chemical composition of : Results and discussion: The LC-MS/MS ... ...

    Abstract Introduction: Oxidative stress plays a causal role in neurodegenerative diseases. The aim of this study is to evaluate the antioxidant and neuroprotective effects of
    Methods: The chemical composition of
    Results and discussion: The LC-MS/MS analysis revealed high content of kaempferol glucuronide (85%) at the extract. IC
    Language English
    Publishing date 2023-03-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2411902-7
    ISSN 1662-453X ; 1662-4548
    ISSN (online) 1662-453X
    ISSN 1662-4548
    DOI 10.3389/fnins.2023.1121029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Updating Ecology and Distribution of Wild Truffles in Morocco

    Henkrar, Fatima / Meyad, Chaimae / Oikrim, Marwa / Bouhaddou, Nezha / Khabar, Lahsen

    Forests. 2023 May 05, v. 14, no. 5

    2023  

    Abstract: The distribution and abundance of the various truffle species are influenced by the climate, soil, and vegetation conditions. The setting of these characteristics is necessary for the potential species’ cultivation. Here, we describe the ecological ... ...

    Abstract The distribution and abundance of the various truffle species are influenced by the climate, soil, and vegetation conditions. The setting of these characteristics is necessary for the potential species’ cultivation. Here, we describe the ecological characteristics of Moroccan truffles and desert truffles and their associations with host plants. We also determine the climate and soil parameters relating to the geographic distribution and fructification of truffles and desert truffles. In contrast to truffles, which are found in sub-humid environments, desert truffles are found in semi-arid and arid regions of Morocco. The dissemination of desert truffles in the Mamora forest and oriental regions of Morocco is typically linked to the presence of Helianthemum sp., whereas the existence of truffles (Tuber spp.) in the Middle Atlas depends on the subsistence of Quercus ilex and Q. faginea. The truffles’ and desert truffles’ fructification depends mainly on the precipitation frequency. Terfezia arenaria and Tuber oligospermum, the two major desert truffles of Mamora forest, require an annual rainfall of 435 mm on average in slightly acidic soil. While the oriental and Highland desert truffles, namely Terfezia boudieri, T. claveryi, and Tirmania spp., require an annual precipitation average of 123 to 267 mm and a high CaCO₃ content. Otherwise, there is Tuber aestivum, localized in humid regions with a rainfall rate of more than 650 mm, and found under calcareous soil rich in organic matter with the presence of potential host plants, such as oaks, cedars, and pines. Our findings open up the possibility of successful cultivation of truffles and desert truffles having an economic interest through understanding their ecological requirements in Morocco.
    Keywords Helianthemum ; Quercus ilex ; Terfezia ; Tirmania ; Tuber aestivum ; acid soils ; calcareous soils ; climate ; ecology ; forests ; fructification ; geographical distribution ; organic matter ; rain ; truffles ; Morocco
    Language English
    Dates of publication 2023-0505
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2527081-3
    ISSN 1999-4907
    ISSN 1999-4907
    DOI 10.3390/f14050952
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: Physiological and pharmacological properties of 5-methoxytryptophol.

    Ouzir, Mounir / Bouhaddou, Nezha / Khalki, Hanane / Lakhdar-Ghazal, Nouria

    Expert review of endocrinology & metabolism

    2019  Volume 8, Issue 4, Page(s) 355–364

    Abstract: 5-methoxytryptophol (5-ML) is a pineal indoleamine derived from serotonin shown to be biologically active in a number of species. This indolamine exhibits a circadian pattern synchronized with the day-night cycle with significant increases during ... ...

    Abstract 5-methoxytryptophol (5-ML) is a pineal indoleamine derived from serotonin shown to be biologically active in a number of species. This indolamine exhibits a circadian pattern synchronized with the day-night cycle with significant increases during daylight, already recognized in vertebrates. The multiplicity of physiological and endocrine functions of 5-ML is remarkable; it is involved in circadian rhythms, reproduction and sexual processes. Furthermore, a number of pharmacological benefits of 5-ML have been reported, including immunomodulatory, antitumor and antioxidative activities. However, the molecular mechanisms of these pharmacological effects remain unclear. The purpose of this article is to provide an overview on the general properties and physiological functions of 5-ML. An attempt has been made to fully document all studies performed using 5-ML. In addition, this article aims to gain insight into the current state of knowledge regarding pharmacological and therapeutic effects of this indoleamine.
    Language English
    Publishing date 2019-02-08
    Publishing country England
    Document type Journal Article
    ISSN 1744-8417
    ISSN (online) 1744-8417
    DOI 10.1586/17446651.2013.811866
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Association between overweight and anemia in Moroccan adolescents: a cross-sectional study.

    Mehdad, Slimane / Benaich, Souad / Hamdouchi, Asmaa El / Bouhaddou, Nezha / Azlaf, Mehdi / Menchawy, Imane El / Belghiti, Hakim / Benkirane, Hasnae / Lahmam, Houria / Barkat, Amina / Kari, Khalid El / Mzibri, Mohamed El / Aguenaou, Hassan

    The Pan African medical journal

    2022  Volume 41, Page(s) 156

    Abstract: Introduction: obesity and anemia remain global public health problems, having major negative effects on human health. We aimed to estimate the prevalence of anemia and investigate its association with overweight/obesity and excess body fat among ... ...

    Abstract Introduction: obesity and anemia remain global public health problems, having major negative effects on human health. We aimed to estimate the prevalence of anemia and investigate its association with overweight/obesity and excess body fat among Moroccan adolescents.
    Methods: a total of 292 adolescents aged 11-17 years were recruited. Body mass index (BMI) and waist circumference (WC) were determined using standardized equipment. Body fat mass was measured by bioelectrical impedance analysis. Hemoglobin concentration was measured by the HemoCue method.
    Results: the overall prevalence of anemia was 13.7%. Anemia was more common among overweight/obese participants (15.2%) compared to non-overweight participants (12.8%). Overweight/obese boys were more likely to experience anemia than their non-overweight peers (odds ratio (OR): 1.49; 95% confidence interval (95%CI): 0.51-4.41). Similarly, anemia likelihood was higher among individuals having excess body fat than those who do not have excess body fat, particularly among girls (OR: 1.64; 95%CI: 0.69-3.87). Excess body fat was also significantly associated with lower hemoglobin concentration in both the total sample and girls (P=0.014, and P=0.041, respectively). Overall, increased BMI, WC, fat mass, and percent body fat were associated with reduced hemoglobin concentrations. There was a significant negative correlation between hemoglobin concentration and BMI among anemic girls (P=0.023).
    Conclusion: elevated BMI and body fat level were associated with lower hemoglobin concentrations and anemia. Further studies are needed to delineate the basis of such associations, and if these findings are confirmed, the guidelines for screening for anemia may need to be modified to include overweight/obesity as a risk factor.
    MeSH term(s) Adolescent ; Anemia/complications ; Anemia/etiology ; Body Mass Index ; Cross-Sectional Studies ; Female ; Hemoglobins ; Humans ; Male ; Obesity/complications ; Obesity/epidemiology ; Overweight/complications ; Overweight/epidemiology ; Prevalence ; Waist Circumference
    Chemical Substances Hemoglobins
    Language English
    Publishing date 2022-02-22
    Publishing country Uganda
    Document type Journal Article
    ZDB-ID 2514347-5
    ISSN 1937-8688 ; 1937-8688
    ISSN (online) 1937-8688
    ISSN 1937-8688
    DOI 10.11604/pamj.2022.41.156.20927
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Phase and period responses of the jerboa Jaculus orientalis to short light pulses.

    El Moussaouiti, Rachid / Bouhaddou, Nezha / Sabbar, Mariam / Cooper, Howard M / Lakhdar-Ghazal, Nouria

    Chronobiology international

    2010  Volume 27, Issue 7, Page(s) 1348–1364

    Abstract: The phase and period responses to short light pulses were studied in the jerboa, a seasonal, hibernating, nocturnal rodent from the Atlas region in Morocco. The jerboa, which is a saltatory species, showed precise activity onsets and offsets under a ... ...

    Abstract The phase and period responses to short light pulses were studied in the jerboa, a seasonal, hibernating, nocturnal rodent from the Atlas region in Morocco. The jerboa, which is a saltatory species, showed precise activity onsets and offsets under a light-dark (LD) cycle using infrared captors to record locomotor activity. When released into constant darkness (DD), the majority of animals showed a circadian period (tau) < 24 h (mean tau = 23.89 +/- 0.13 h) and a lengthening of the activity span, alpha. Animals were subsequently exposed to up to eight 15-min light pulses, each separated by at least 2 wks, for up to 160 days in DD. During this span, most individuals maintained robust circadian rhythmicity, with clearly defined activity onsets and offsets, similar levels of total activity, duration of alpha, and percent activity occurring during the subjective night. The phase response curve (PRC) is typical of other nocturnal rodents, with light eliciting delays during late subjective day and early subjective night (CT8-CT19) and advances during late subjective night to early subjective day (CT19-CT2). A dead zone, when light had no effect on phase, is observed during mid-subjective day (CT3-CT8). A few individuals showed large (> 9 h) Type 0 phase resetting near the singularity region (CT19) that resulted in a complete phase reversal, but otherwise displayed normal phase-shifting responses at other CT times. The tau response curve showed a decrease in period from early to late subjective night with increases at other times, but these changes were small (maximum < 9 min) and highly variable. There was a distinct tendency for animals that had an initial short tau in DD to conserve a short tau during the series of light pulses and, inversely, for animals with long tau to conserve a long tau. This suggests possible constraints on the plasticity of variation of tau in relation to the endogenous period of the animal.
    MeSH term(s) Animals ; Biological Clocks/physiology ; Circadian Rhythm/physiology ; Darkness ; Light ; Motor Activity/physiology ; Photoperiod ; Rodentia/physiology
    Language English
    Publishing date 2010-08
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 998996-1
    ISSN 1525-6073 ; 0742-0528
    ISSN (online) 1525-6073
    ISSN 0742-0528
    DOI 10.3109/07420528.2010.504315
    Database MEDical Literature Analysis and Retrieval System OnLINE

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