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Article: Prophylactic Administration of Alpha Blocker for the Prevention of Urinary Retention in Males Undergoing Inguinal Hernia Repair Under Spinal Anesthesia: Interim Analysis of a Randomized Controlled Trial.

Koukoulis, Georgios D / Bouliaris, Konstantinos / Perivoliotis, Konstantinos / Tepetes, Konstantinos

2021 Volume 13, Issue 11, Page(s) e19669

Abstract: Introduction: This randomized controlled study aims to investigate the prophylactic effect of tamsulosin on the development of postoperative urinary retention (POUR) in men undergoing elective open inguinal hernia (IH) repair under spinal anesthesia. ... ...

Abstract	Introduction: This randomized controlled study aims to investigate the prophylactic effect of tamsulosin on the development of postoperative urinary retention (POUR) in men undergoing elective open inguinal hernia (IH) repair under spinal anesthesia. The study also focused on potentially predisposing factors for POUR. Methods: 100 eligible patients were randomized into two groups. Patients in the experimental group were given two doses of tamsulosin 0.4 mg orally 24 hours and 6 hours before surgery. In the control group, two doses of placebo were administered, in the same manner as the study group. The following parameters were also recorded: the International Prostate Symptom Score (IPSS) questionnaire scores, the presence of scrotal hernia, operation duration, perioperative administration of IV opioids and/or atropine, postoperative pain, and preoperative anxiety. Results: Overall, the incidence of POUR was 37% (37/100) with no difference between the two groups. Among patients receiving tamsulosin, 39.2% (20/51) developed POUR, compared to 34.7% (17/49) in the control group. Preoperative patients' high anxiety visual analog scale (VAS) score (>51mm) (P=0.007) and the intraoperative use of atropine (P=0.02) were detected as risk factors for POUR. Conclusion: This interim analysis of our prospective randomized trial showed no benefit from the prophylactic use of tamsulosin in preventing POUR after IH repair under spinal anesthesia. This type of anesthesia was also correlated with an overall high incidence of POUR. Preoperative anxiety and administration of atropine were identified as statistically significant factors for POUR. In patients with preoperative high anxiety, VAS score a different type of anesthesia may be used.
Language	English
Publishing date	2021-11-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.19669
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Laparoscopic bilateral inguinal hernia repair: Should it be the preferred technique?

Doudakmanis, Christos / Kolla, Christina / Bouliaris, Konstantinos / Efthimiou, Matthaios / Koukoulis, Georgios D

World journal of methodology

2022 Volume 12, Issue 4, Page(s) 193–199

Abstract: Inguinal hernias are amongst the most common conditions requiring general surgical intervention. For decades, the preferred approach was the open repair. As laparoscopy became more popular and available and more surgeons became familiarized with this ... ...

Abstract	Inguinal hernias are amongst the most common conditions requiring general surgical intervention. For decades, the preferred approach was the open repair. As laparoscopy became more popular and available and more surgeons became familiarized with this modality, laparoscopic inguinal hernia repair became an alternative. The aim of this study is to assess the effectiveness of laparoscopic inguinal repair, with a focus on bilateral inguinal hernias. Initial reports have shown promising clinical outcomes compared to those of conventional repair of bilateral hernias. However, there are only a few studies concerning laparoscopic repair of bilateral hernias. It is yet to be proven that laparoscopy is the "gold standard" in the treatment of bilateral inguinal hernias. So far, the choice of an inguinal hernia repair technique has been up to each surgeon, depending on their expertise and available resources after taking into consideration each patient's needs.
Language	English
Publishing date	2022-07-20
Publishing country	United States
Document type	Journal Article ; Review
ISSN	2222-0682
ISSN	2222-0682
DOI	10.5662/wjm.v12.i4.193
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Article: Palliative Treatment of Bowel Obstruction With Colostomy Under Local Anesthesia in Frail Patients: A Single-Site Experience.

Doudakmanis, Christos / Baxevanidou, Kyriaki / Chatzikomnitsa, Paraskevi / Kolla, Christina / Bouliaris, Konstantinos / Giaglaras, Anargiros / Efthimiou, Matthaios / Koukoulis, Georgios D

Cureus

2023 Volume 15, Issue 9, Page(s) e45698

Abstract: Introduction: Attendance of patients to the emergency department due to acute large bowel obstruction is a common phenomenon. Most of these patients are elderly, critically ill, and with high comorbidity. The literature suggests that more than 50% of ... ...

Abstract	Introduction: Attendance of patients to the emergency department due to acute large bowel obstruction is a common phenomenon. Most of these patients are elderly, critically ill, and with high comorbidity. The literature suggests that more than 50% of these cases are due to colon cancer. Since this condition is considered to be an emergency, immediate intervention and response is imperative. Purpose: The aim of the present study is to present our surgical technique of colostomy formation under local anesthesia in selected critically ill patients, with increased perioperative risk and acute large bowel obstruction. Materials and methods: This is a retrospective study of 24 patients, with obstipation, who underwent emergency colostomy under local anesthesia, during the period from 2014 to 2021. Results: The mean age of the patients was 77 years. The vast majority of patients had an American Society of Anesthesiologists (ASA) score of ≥3 and a Charlson score of ≥7. The most common colostomy was transverse colostomy (21/24 patients). The patients' hospitalization ranged from four to 42 days. Only one patient died. All colostomies functioned properly in the immediate postoperative period. Only one patient required postoperative admission to the ICU. Conclusions: Colostomy under local anesthesia in critically ill, elderly patients is an alternative option for the treatment of ileus.
Language	English
Publishing date	2023-09-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.45698
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Article: Bacterial translocation in patients undergoing major gastrointestinal surgery and its role in postoperative sepsis.

Doudakmanis, Christos / Bouliaris, Konstantinos / Kolla, Christina / Efthimiou, Matthaios / Koukoulis, Georgios D

World journal of gastrointestinal pathophysiology

2021 Volume 12, Issue 6, Page(s) 106–114

Abstract: Bacteria of the human intestinal microflora have a dual role. They promote digestion and are part of a defense mechanism against pathogens. These bacteria could become potential pathogens under certain circumstances. The term "bacterial translocation" ... ...

Abstract	Bacteria of the human intestinal microflora have a dual role. They promote digestion and are part of a defense mechanism against pathogens. These bacteria could become potential pathogens under certain circumstances. The term "bacterial translocation" describes the passage of bacteria of the gastrointestinal tract through the intestinal mucosa barrier to mesenteric lymph nodes and other organs. In some cases, the passage of bacteria and endotoxins could result in blood stream infections and in multiple organ failure. Open elective abdominal surgery more frequently results in malfunction of the intestinal barrier and subsequent bacterial translocation and blood stream infections than laparoscopic surgery. Postoperative sepsis is a common finding in patients who have undergone non-elective abdominal surgeries, including trauma patients treated with laparotomy. Postoperative sepsis is an emerging issue, as it changes the treatment plan in surgical patients and prolongs hospital stay. The association between bacterial translocation and postoperative sepsis could provide novel treatment options.
Language	English
Publishing date	2021-11-28
Publishing country	United States
Document type	Editorial
ZDB-ID	2583474-5
ISSN	2150-5330
ISSN	2150-5330
DOI	10.4291/wjgp.v12.i6.106
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Article: Manual Reduction of Incarcerated Abdominal Wall Hernias. A Feasible Option during COVID-19 Pandemic: A Prospective Study.

Bouliaris, Konstantinos / Efthimiou, Matthaios / Chatzikomnitsa, Paraskevi / Kolla, Christina / Doudakmanis, Christos / Zervas, Konstantinos / Giaglaras, Anargiros / Koukoulis, Georgios D

Surgery journal (New York, N.Y.)

2022 Volume 8, Issue 1, Page(s) e46–e51

Abstract: ... ...

Abstract	Background
Language	English
Publishing date	2022-02-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	2864275-2
ISSN	2378-5136 ; 2378-5128
ISSN (online)	2378-5136
ISSN	2378-5128
DOI	10.1055/s-0041-1742178
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Article ; Online: Lymph node ratio as a prognostic factor in gastric cancer patients following D1 resection. Comparison with the current TNM staging system.

Bouliaris, K / Rachiotis, G / Diamantis, A / Christodoulidis, G / Polychronopoulou, E / Tepetes, K

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

2017 Volume 43, Issue 7, Page(s) 1350–1356

Abstract: Introduction: Nodal ratio (NR) has been demonstrated to be an independent prognostic factor in patients with gastric cancer. We evaluated the prognostic role of NR comparing it with the current TNM (2010) classification in gastric cancer patients ... ...

Abstract	Introduction: Nodal ratio (NR) has been demonstrated to be an independent prognostic factor in patients with gastric cancer. We evaluated the prognostic role of NR comparing it with the current TNM (2010) classification in gastric cancer patients treated with curative (R0) D1 resection. Materials and methods: We retrospectively reviewed 110 patients who underwent R0 resection for gastric cancer at University Hospital of Larissa between 2002 and 2011. All patients had a D1 lymphadenectomy plus the nodes along the left gastric artery. Factors affecting survival as well as correlations between the N status, NR status and resected nodes were investigated. Results: In univariate analysis the N and NR status but not the numbers of retrieved nodes were significant prognostic factors. Inside N1 and N2 categories, patients with different NR groups were present and survival of some of these subpopulations was statistically different at long-rank test. There was a correlation between the nodes retrieved and N status but not with the NR category. In multivariate analysis both N status (HR=1.45; 95% C.I. = 1.19-1.89) and NR (HR=4.53; 95% C.I. = 1.86-11.03) found to be independent prognostic factors of survival. Conclusion: Prognostic significance of N status and NR status was comparable. Unlike N status, NR is independent by the number of resected nodes, and therefore it is particularly useful in case of conventional lymphadenectomy.
MeSH term(s)	Adenocarcinoma/secondary ; Adenocarcinoma/surgery ; Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Lymph Node Excision ; Lymph Nodes/pathology ; Lymph Nodes/surgery ; Lymphatic Metastasis ; Male ; Middle Aged ; Neoplasm Staging ; Prognosis ; Retrospective Studies ; Stomach Neoplasms/pathology ; Stomach Neoplasms/surgery ; Survival Rate
Language	English
Publishing date	2017-07
Publishing country	England
Document type	Comparative Study ; Journal Article
ZDB-ID	632519-1
ISSN	1532-2157 ; 0748-7983
ISSN (online)	1532-2157
ISSN	0748-7983
DOI	10.1016/j.ejso.2017.03.013
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Zs.A 1149: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 549: Show issues

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Article ; Online: Vertebral erosion: a rare complication of tracheostomy tube.

Bouliaris, Konstantinos / Alexiou, Evangelos / Karagiannis, Spyridon / Zafeiridis, Tilemachos

Intensive care medicine

2017 Volume 43, Issue 2, Page(s) 267–268

MeSH term(s)	Equipment Failure ; Humans ; Magnetic Resonance Imaging ; Male ; Osteomyelitis/diagnostic imaging ; Osteomyelitis/etiology ; Respiration, Artificial/adverse effects ; Spinal Diseases/etiology ; Thoracic Vertebrae/diagnostic imaging ; Thorax/diagnostic imaging ; Tomography, X-Ray Computed ; Tracheostomy/adverse effects ; Tracheostomy/instrumentation ; Young Adult
Language	English
Publishing date	2017-02
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	80387-x
ISSN	1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
ISSN (online)	1432-1238
ISSN	0340-0964 ; 0342-4642 ; 0935-1701
DOI	10.1007/s00134-016-4561-7
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Zs.A 1089: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Gastrointestinal Stromal Tumor (GIST) and Synchronous Intra-Abdominal Liposarcoma: A Report of Two Rare Cases and Literature Review.

Diamantis, Alexandros / Samara, Athina A / Baloyiannis, Ioannis / Symeonidis, Dimitrios / Diamantis, Andreas-Marios / Tolia, Maria / Bouliaris, Konstantinos / Koukoulis, Georgios / Tepetes, Konstantinos

International journal of surgical oncology

2021 Volume 2021, Page(s) 2626635

Abstract: Introduction: Gastrointestinal stromal tumors (GISTs) quite frequently occur synchronously with other malignancies, with most cases being adenocarcinomas. GISTs and liposarcomas are both of mesenchymal origin, and their coexistence is extremely rare.: ...

Abstract	Introduction: Gastrointestinal stromal tumors (GISTs) quite frequently occur synchronously with other malignancies, with most cases being adenocarcinomas. GISTs and liposarcomas are both of mesenchymal origin, and their coexistence is extremely rare. Methods: We conducted a review of the current literature regarding the synchronous occurrence of GISTs and intra-abdominal liposarcomas. An electronic search of the literature was undertaken using MEDLINE (database provider PubMed). Furthermore, we present the first described case of an 86-year-old male with a GIST and synchronous liposarcoma, both located in the stomach, as well as a 66-year-old male with a gastric GIST and concurrent retroperitoneal liposarcoma. Results: A total of 5 cases of synchronous GIST and intra-abdominal liposarcoma have been reported in the literature to date, with the most recent cases included in the present study. Conclusion: Further research is required to explain any possible correlation in the coexistence of these different neoplasms of the same origin. Meanwhile, R0 resection of both tumors remains the treatment of choice.
MeSH term(s)	Adenocarcinoma ; Aged ; Aged, 80 and over ; Female ; Gastrointestinal Stromal Tumors/diagnostic imaging ; Gastrointestinal Stromal Tumors/surgery ; Humans ; Liposarcoma/diagnostic imaging ; Liposarcoma/surgery ; Male ; Middle Aged ; Retroperitoneal Neoplasms/diagnostic imaging ; Retroperitoneal Neoplasms/surgery ; Stomach Neoplasms
Language	English
Publishing date	2021-09-01
Publishing country	United States
Document type	Case Reports ; Journal Article ; Review
ZDB-ID	2584964-5
ISSN	2090-1410 ; 2090-1410
ISSN (online)	2090-1410
ISSN	2090-1410
DOI	10.1155/2021/2626635
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Article: Metastasectomy of pancreatic and periampullary adenocarcinoma to solid organ: The current evidence.

Saedon, Mahmud / Maroulis, Ioannis / Brooks, Adam / Alexiou, Evangelos / Bouliaris, Konstantinos / Amanatidis, Theofilos / Germanos, Stylianos

Journal of B.U.ON. : official journal of the Balkan Union of Oncology

2019 Volume 23, Issue 6, Page(s) 1648–1654

Abstract: Purpose: Pancreatic and periampullary adenocarcinoma have not generally been included in the tumour types considered for metastasectomy. However, there is an increasing interest that metastasectomy in well-selected patients can prolong survival. This ... ...

Abstract	Purpose: Pancreatic and periampullary adenocarcinoma have not generally been included in the tumour types considered for metastasectomy. However, there is an increasing interest that metastasectomy in well-selected patients can prolong survival. This review aims to establish the recent evidence on the surgical management of oligometastatic disease and survival outcome in patients who underwent metastasectomy focusing on isolated hepatic and pulmonary metastases. Methods: A systematic search was performed in the PubMed database to identify all original articles on the role of metastasectomy for oligometastasis of pancreatic and periampullary adenocarcinoma. Data on methodologies used, 1,3,5 - year survival and median overall survival were summarized, and used to address relevant clinical questions related to the survival outcome in patients who underwent metastasectomy. Results: Sixteen studies were included in this review. All the studies included were retrospective and heterogenous in nature and did not have a uniform reporting on survival outcomes. Conclusion: There is insufficient evidence to support a change of current practice in managing metastatic pancreatic and periampullary cancer. However, patients with ampullary cancer as the primary and any patients with first recurrence as isolated pulmonary metastases had better prognosis than patients with synchronous metastasis or metastases to the liver. This need to be explored in future studies.
MeSH term(s)	Adenocarcinoma/secondary ; Adenocarcinoma/surgery ; Ampulla of Vater/pathology ; Ampulla of Vater/surgery ; Common Bile Duct Neoplasms/secondary ; Common Bile Duct Neoplasms/surgery ; Humans ; Metastasectomy/mortality ; Neoplasms/pathology ; Neoplasms/surgery ; Pancreatic Neoplasms/secondary ; Pancreatic Neoplasms/surgery ; Prognosis ; Survival Rate
Language	English
Publishing date	2019-01-04
Publishing country	Greece
Document type	Journal Article ; Meta-Analysis ; Systematic Review
ZDB-ID	2040386-0
ISSN	2241-6293 ; 1107-0625
ISSN (online)	2241-6293
ISSN	1107-0625
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Zs.A 5438: Show issues

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Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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ab Jg. 2022: Lesesaal (EG)

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Article: Gastrointestinal stromal tumors and synchronous intra-abdominal malignancies: Review of the literature.

Diamantis, Alexandros / Bouliaris, Konstantinos / Christodoulidis, Grigorios / Vasdeki, Dionysia / Perivoliotis, Konstantinos / Tepetes, Konstantinos

Journal of B.U.ON. : official journal of the Balkan Union of Oncology

2019 Volume 23, Issue 6, Page(s) 1573–1579

Abstract: Purpose: Gastrointestinal stromal tumors (GISTs) are the most frequent neoplasms of mesenchymal origin affecting the gastrointestinal tract. GISTs quite frequently co-exist with other primary tumors in up to 33% of the cases. Such occurrence has been ... ...

Abstract	Purpose: Gastrointestinal stromal tumors (GISTs) are the most frequent neoplasms of mesenchymal origin affecting the gastrointestinal tract. GISTs quite frequently co-exist with other primary tumors in up to 33% of the cases. Such occurrence has been mainly described in the literature in the form of case reports and rarely of case series which hasn't been sufficient to prove if there is any association between these two entities. Methods: We conducted a review of the current literature regarding the synchronous occurrence of GISTs and other intra-abdominal malignancies. An electronic search of the literature was undertaken using MEDLINE (database provider PubMed). A primary selection of relevant studies was based on the title and abstract, whereas a secondary selection was performed according to the full text of publications. Results: Ten retrospective case series were considered and overall 1108 GISTs patients were included. Synchronous intra-abdominal malignancies were found in 18% of all GISTs patients studied. The mean age was 70,5 years, affecting more the male gender (65%). The mean size of the concurrent GISTs were 18mm while the most common GIST-associated malignancy were gastric adenocarcinomas. Conclusion: The synchronous occurrence of GISTs and other intra-abdominal primary tumors is more common that it has been considered and while it is not yet clear if there is a causal association for the concomitant occurrence of GIST with other malignancies a closer surveillance of GIST patients is needed due to their proved increased prevalence of a second primary tumor especially during the first year after diagnosis.
MeSH term(s)	Abdominal Neoplasms/complications ; Abdominal Neoplasms/pathology ; Gastrointestinal Neoplasms/complications ; Gastrointestinal Neoplasms/pathology ; Gastrointestinal Stromal Tumors/complications ; Gastrointestinal Stromal Tumors/pathology ; Humans ; Neoplasms, Multiple Primary/complications ; Neoplasms, Multiple Primary/pathology ; Prognosis
Language	English
Publishing date	2019-01-04
Publishing country	Greece
Document type	Journal Article ; Review
ZDB-ID	2040386-0
ISSN	2241-6293 ; 1107-0625
ISSN (online)	2241-6293
ISSN	1107-0625
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5438: Show issues

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Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

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