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  1. Article ; Online: Cardiovascular disease and the risk of incident falls and mortality among adults aged ≥ 65 years presenting to the emergency department: a cohort study from national registry data in Denmark.

    O'Halloran, Aisling M / Cremers, Jolien / Vrangbæk, Karsten / Roe, Lorna / Bourke, Robert / Mortensen, Laust H / Westendorp, Rudi G J / Kenny, Rose Anne

    BMC geriatrics

    2024  Volume 24, Issue 1, Page(s) 93

    Abstract: Background: Falls cause 58% of injury-related Emergency Department (ED) attendances. Previous research has highlighted the potential role of cardiovascular risk factors for falls. This study investigated the impact of cardiovascular disease (CVD) risk ... ...

    Abstract Background: Falls cause 58% of injury-related Emergency Department (ED) attendances. Previous research has highlighted the potential role of cardiovascular risk factors for falls. This study investigated the impact of cardiovascular disease (CVD) risk on three-year incident falls, with presentation to the ED, and mortality.
    Methods: A matched cohort study design was employed using national registry data from 82,292 adults (33% male) aged ≥ 65 years living in Denmark who attended the ED in 2013. We compared age and gender matched ED attendees presenting with a fall versus another reason. The cohort was followed for three-year incident falls, with presentation to the ED, and mortality. The impact of falls-related CVDs was also examined.
    Results: Three-year incident falls was twofold higher among age and gender matched ED attendees aged ≥ 65 years presenting with a fall versus another reason at baseline. A presentation of falls with hip fracture had the highest percentage of incident falls in the 65-74 age group (22%) and the highest percentage mortality in all age groups (27-62%). CVD was not a significant factor in presenting with a fall at the ED, nor did it contribute significantly to the prediction of three-year incident falls. CVD was strongly associated with mortality risk among the ED fall group (RR = 1.81, 95% CI: 1.67-1.97) and showed interactions with both age and fall history.
    Conclusion: In this large study of adults aged ≥ 65 years attending the ED utilising data from national administrative registers in Denmark, we confirm that older adults attending the ED with a fall, including those with hip fracture, were at greatest risk for future falls. While CVD did not predict incident falls, it increased the risk of mortality in the three-year follow up with advancing age. This may be informative for the provision of care pathways for older adults attending the ED due to a fall.
    MeSH term(s) Humans ; Male ; Aged ; Female ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/epidemiology ; Cohort Studies ; Routinely Collected Health Data ; Emergency Service, Hospital ; Hip Fractures ; Denmark/epidemiology
    Language English
    Publishing date 2024-01-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2059865-8
    ISSN 1471-2318 ; 1471-2318
    ISSN (online) 1471-2318
    ISSN 1471-2318
    DOI 10.1186/s12877-023-04618-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: What does cognitive screening reveal about early cognitive performance following endovascular clot retrieval and intravenous thrombolysis in acute ischaemic stroke?

    Humphrey, Sam / Pike, Kerryn E / Long, Brian / Ma, Henry / Bourke, Robert / Byrne, Danielle / Wright, Bradley / Wong, Dana

    Brain impairment : a multidisciplinary journal of the Australian Society for the Study of Brain Impairment

    2024  Volume 25

    Abstract: Background Little is known regarding cognitive outcomes following treatment with endovascular clot retrieval (ECR) and intravenous tissue plasminogen activator (t-PA). We aimed to determine if there were any differences on a measure of cognitive ... ...

    Abstract Background Little is known regarding cognitive outcomes following treatment with endovascular clot retrieval (ECR) and intravenous tissue plasminogen activator (t-PA). We aimed to determine if there were any differences on a measure of cognitive screening between patients treated with ECR, t-PA, and those who were managed conservatively. Methods The medical records of ischaemic stroke patients admitted to Monash Medical Centre between January 2019 and December 2019 were retrospectively reviewed. Information extracted from medical records included age, sex, National Institutes of Health Stroke Scale at presentation, location of occlusion, treatment type, medical history, and cognitive screening performance measured by the Montreal Cognitive Assessment (MoCA). Results Eighty-two patients met the inclusion criteria (mean age = 66.5 ± 13.9; 49 male, 33 female). Patients treated with ECR performed significantly better on the MoCA (n  = 36, 24.1 ± 4.3) compared to those who were managed conservatively (n  = 26, 20.7 ± 5.5). Performance for patients treated with t-PA (n  = 20, 23.9 ± 3.5) fell between the ECR and conservative management groups, but they did not significantly differ from either. Conclusion Our retrospective chart review found that ischaemic stroke patients treated with ECR appear to perform better on cognitive screening compared to patients who are managed conservatively. We also found that patients treated with ECR and t-PA appear to have similar cognitive screening performances in the acute stages following ischaemic stroke, although this finding is likely to have been impacted by group differences in stroke characteristics and may reflect the possibility that the ECR group performed better than expected based on their stroke severity.
    MeSH term(s) Humans ; Male ; Female ; Middle Aged ; Aged ; Aged, 80 and over ; Tissue Plasminogen Activator/therapeutic use ; Stroke/drug therapy ; Brain Ischemia/drug therapy ; Fibrinolytic Agents/therapeutic use ; Retrospective Studies ; Ischemic Stroke/drug therapy ; Thrombosis/drug therapy ; Thrombolytic Therapy/methods ; Cognition
    Chemical Substances Tissue Plasminogen Activator (EC 3.4.21.68) ; Fibrinolytic Agents
    Language English
    Publishing date 2024-04-02
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2180113-7
    ISSN 1839-5252 ; 1443-9646
    ISSN (online) 1839-5252
    ISSN 1443-9646
    DOI 10.1071/IB23066
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Bilateral Subretinal Fluid Mimicking Subretinal Neovascularization Within 24 Hours After Selective Laser Trabeculoplasty.

    Phillis, Charles A / Bourke, Robert D

    Journal of glaucoma

    2016  Volume 25, Issue 2, Page(s) e110–4

    Abstract: Purpose: Selective laser trabeculoplasty (SLT), which is widely regarded as a safe procedure, is a frequently used treatment for open-angle glaucoma. Although it is presumed to be associated with an inflammatory cascade and possible postoperative ... ...

    Abstract Purpose: Selective laser trabeculoplasty (SLT), which is widely regarded as a safe procedure, is a frequently used treatment for open-angle glaucoma. Although it is presumed to be associated with an inflammatory cascade and possible postoperative inflammation, only 2 cases of SLT complicated by cystoid macular edema have been previously reported. Until now there are no previous reports of SLT causing subretinal fluid (SRF).
    Methods/importance: Clinical examination, optical coherence tomography, and fluorescein angiography demonstrated a previously unreported clinical entity consisting of bilateral SRF, developing within 24 hours of bilateral inferior 180-degree SLT for open-angle glaucoma.
    Results: Rapid bilateral, subjective loss of vision occurred within 24 hours post-SLT. This was associated with bilateral SRF resulting in 48 μm (OD) and 35 μm (OS) increase in macular thickness on optical coherence tomography. Fundus fluorescein angiography demonstrated profuse, well-demarcated subfoveal leakage. SRF resolved within 4 days, but eventual best corrected visual acuity was subjectively and objectively decreased.
    Conclusions: The sudden onset of loss of vision and the development of subfoveal SRF within 24 hours of SLT strongly suggests cause and effect. This previously unreported clinical entity of bilateral SRF within 24 hours of SLT may be secondary to an intraocular inflammatory cascade, similar to previous hypotheses regarding 3 cases of cystoid macular edema post-SLT. Given the dramatic initial loss of vision and compromised long-term visual outcome, clinicians and patients need to be informed of this new clinical entity of SLT associated with SRF and permanent retinal pigment epithelial changes.
    MeSH term(s) Aged ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Blood-Retinal Barrier ; Corneal Pachymetry ; Drug Therapy, Combination ; Female ; Fluorescein Angiography ; Fluorometholone/therapeutic use ; Glaucoma, Open-Angle/surgery ; Glucocorticoids/therapeutic use ; Humans ; Intraocular Pressure ; Ketorolac/therapeutic use ; Laser Therapy/adverse effects ; Retinal Neovascularization/diagnosis ; Retinal Neovascularization/drug therapy ; Retinal Neovascularization/etiology ; Subretinal Fluid ; Tomography, Optical Coherence ; Trabeculectomy/adverse effects ; Visual Acuity
    Chemical Substances Anti-Inflammatory Agents, Non-Steroidal ; Glucocorticoids ; Fluorometholone (SV0CSG527L) ; Ketorolac (YZI5105V0L)
    Language English
    Publishing date 2016-02
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 913494-3
    ISSN 1536-481X ; 1057-0829
    ISSN (online) 1536-481X
    ISSN 1057-0829
    DOI 10.1097/IJG.0000000000000259
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Is orthostatic hypotension and co-existing supine and seated hypertension associated with future falls in community-dwelling older adults? Results from The Irish Longitudinal Study on Ageing (TILDA).

    Donoghue, Orna A / O'Connell, Matthew D L / Bourke, Robert / Kenny, Rose Anne

    PloS one

    2021  Volume 16, Issue 5, Page(s) e0252212

    Abstract: Orthostatic hypotension (OH) often co-exists with hypertension. As increasing age affects baroreflex sensitivity, it loses its ability to reduce blood pressure when lying down. Therefore, supine hypertension may be an important indicator of baroreflex ... ...

    Abstract Orthostatic hypotension (OH) often co-exists with hypertension. As increasing age affects baroreflex sensitivity, it loses its ability to reduce blood pressure when lying down. Therefore, supine hypertension may be an important indicator of baroreflex function. This study examines (i) the association between OH and future falls in community-dwelling older adults and (ii) if these associations persist in those with co-existing OH and baseline hypertension, measured supine and seated. Data from 1500 community-dwelling adults aged ≥65 years from The Irish Longitudinal Study on Ageing (TILDA) were used. Continuous beat-to-beat blood pressure was measured using digital photoplethysmography during an active stand procedure with OH defined as a drop in systolic blood pressure (SBP) ≥20 mmHg and/or ≥10 mm Hg in diastolic blood pressure (DBP) within 3 minutes of standing. OH at 40 seconds (OH40) was used as a marker of impaired early stabilisation and OH sustained over the second minute (sustained OH) was used to indicate a more persistent deficit, similar to traditional OH definitions. Seated and supine hypertension were defined as SBP ≥140 mm Hg or DBP ≥90 mm Hg. Modified Poisson models were used to estimate relative risk of falls (recurrent, injurious, unexplained) and syncope occurring over four year follow-up. OH40 was independently associated with recurrent (RR = 1.30, 95% CI = 1.02,1.65), injurious (RR = 1.43, 95% CI = 1.13,1.79) and unexplained falls (RR = 1.55, 95% CI = 1.13,2.13). Sustained OH was associated with injurious (RR = 1.55, 95% CI = 1.18,2.05) and unexplained falls (RR = 1.63, 95% CI = 1.06,2.50). OH and co-existing hypertension was associated with all falls outcomes but effect sizes were consistently larger with seated versus supine hypertension. OH, particularly when co-existing with hypertension, was independently associated with increased risk of future falls. Stronger effect sizes were observed with seated versus supine hypertension. This supports previous findings and highlights the importance of assessing orthostatic blood pressure behaviour in older adults at risk of falls and with hypertension. Observed associations may reflect underlying comorbidities, reduced cerebral perfusion or presence of white matter hyperintensities.
    MeSH term(s) Aged ; Aging ; Female ; Humans ; Hypertension/epidemiology ; Hypotension, Orthostatic/epidemiology ; Independent Living ; Ireland ; Longitudinal Studies ; Male ; Middle Aged ; Prospective Studies ; Risk Factors
    Language English
    Publishing date 2021-05-27
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0252212
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Diagnostic and Therapeutic Challenges.

    Phillis, Charles A / Bourke, Robert D / Major, James C

    Retina (Philadelphia, Pa.)

    2016  Volume 36, Issue 6, Page(s) 1234–1236

    MeSH term(s) Adenocarcinoma/secondary ; Adenocarcinoma/therapy ; Brain Neoplasms/secondary ; Brain Neoplasms/therapy ; Breast Neoplasms/pathology ; Breast Neoplasms/therapy ; Chemoradiotherapy ; Endotamponade ; Female ; Fluorocarbons/administration & dosage ; Humans ; Middle Aged ; Pancreatic Neoplasms/pathology ; Pancreatic Neoplasms/therapy ; Retinal Detachment/diagnosis ; Retinal Detachment/surgery ; Silicone Oils ; Stomach Neoplasms/pathology ; Stomach Neoplasms/therapy ; Subretinal Fluid/diagnostic imaging ; Tomography, Optical Coherence ; Vitrectomy
    Chemical Substances Fluorocarbons ; Silicone Oils
    Language English
    Publishing date 2016-06
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 603192-4
    ISSN 1539-2864 ; 0275-004X
    ISSN (online) 1539-2864
    ISSN 0275-004X
    DOI 10.1097/IAE.0000000000000880
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Short-term intraocular tamponade with perfluorocarbon heavy liquid.

    Drury, Brett / Bourke, Robert D

    The British journal of ophthalmology

    2011  Volume 95, Issue 5, Page(s) 694–698

    Abstract: Background: Inferior retinal detachment pathology can be difficult to manage due to inadequate tamponade with low specific gravity tamponade agents and the propensity for the development of proliferative vitreoretinopathy (PVR). We report the efficacy ... ...

    Abstract Background: Inferior retinal detachment pathology can be difficult to manage due to inadequate tamponade with low specific gravity tamponade agents and the propensity for the development of proliferative vitreoretinopathy (PVR). We report the efficacy and adverse effects associated with the use of perfluorocarbon heavy liquid as a short-term tamponade in managing such pathologies.
    Methods: Retrospective analysis of 17 eyes treated with short-term perfluoro-n-octane tamponade for complex inferior retinal pathology, including inferior detachment and PVR. Mean follow-up time was 14 months and mean tamponade duration was 7 days.
    Results: Reattachment of the retina during the study period was achieved with a single set of operations in 13/17 (76%) eyes, with four eyes requiring a subsequent set of vitreoretinal operations. Postoperative visual acuity (VA) was equal to or better than preoperative VA in 14 (82%) of 17 eyes. Complications arising during the follow-up period included superior redetachment, atrophic macular changes, minor macular haemorrhage, cataract, elevated intraocular pressure, corneal defects, PVR, epiretinal membrane and retained perfluorocarbon heavy liquid. One case of intraocular inflammation occurred >6 months after removal of perfluoro-n-octane tamponade.
    Conclusion: Short-term perfluoro-n-octane tamponade achieved a stable reattachment rate of 76% when used to manage challenging retinal pathologies.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Female ; Fluorocarbons/administration & dosage ; Humans ; Male ; Middle Aged ; Retinal Detachment/complications ; Retinal Detachment/therapy ; Retrospective Studies ; Silicone Oils/administration & dosage ; Treatment Outcome ; Visual Acuity/physiology ; Vitrectomy/methods ; Vitreoretinopathy, Proliferative/complications ; Vitreoretinopathy, Proliferative/therapy ; Vitreous Body ; Young Adult
    Chemical Substances Fluorocarbons ; Silicone Oils ; perfluorooctane (6P60ZBK0QL)
    Language English
    Publishing date 2011-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 80078-8
    ISSN 1468-2079 ; 0007-1161
    ISSN (online) 1468-2079
    ISSN 0007-1161
    DOI 10.1136/bjo.2009.175216
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Intravitreal injections: a review of the evidence for best practice: comment.

    Vote, Brendan J / Chang, Andrew / Bourke, Robert

    Clinical & experimental ophthalmology

    2014  Volume 42, Issue 1, Page(s) 96–98

    MeSH term(s) Angiogenesis Inhibitors/administration & dosage ; Humans ; Intravitreal Injections/methods ; Vitreous Body/drug effects
    Chemical Substances Angiogenesis Inhibitors
    Language English
    Publishing date 2014-01
    Publishing country Australia
    Document type Comment ; Letter
    ZDB-ID 2014008-3
    ISSN 1442-9071 ; 1442-6404
    ISSN (online) 1442-9071
    ISSN 1442-6404
    DOI 10.1111/ceo.12257
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Psychometric deficits in autoimmune encephalitis: A retrospective study from the Australian Autoimmune Encephalitis Consortium.

    Griffith, Sarah / Wesselingh, Robb / Broadley, James / O'Shea, Marie / Kyndt, Chris / Meade, Catherine / Long, Brian / Seneviratne, Udaya / Reidy, Natalie / Bourke, Robert / Buzzard, Katherine / D'Souza, Wendyl / Macdonell, Richard / Brodtmann, Amy / Butzkueven, Helmut / O'Brien, Terence J / Alpitsis, Rubina / Malpas, Charles B / Monif, Mastura

    European journal of neurology

    2022  Volume 29, Issue 8, Page(s) 2355–2366

    Abstract: Background and purpose: Despite the rapid increase in research examining outcomes in autoimmune encephalitis (AE) patients, there are few cohort studies examining cognitive outcomes in this population. The current study aimed to characterise ... ...

    Abstract Background and purpose: Despite the rapid increase in research examining outcomes in autoimmune encephalitis (AE) patients, there are few cohort studies examining cognitive outcomes in this population. The current study aimed to characterise psychometric outcomes in this population, and explore variables that may predict psychometric outcomes.
    Methods: This retrospective observational study collected psychometric data from 59 patients across six secondary and tertiary referral centres in metropolitan hospitals in Victoria, Australia between January 2008 and July 2019. Frequency and pattern analysis were employed to define and characterize psychometric outcomes. Univariable logistic regression was performed to examine predictors of intact and pathological psychometric outcomes.
    Results: Deficits in psychometric markers of executive dysfunction were the most common finding in this cohort, followed by deficits on tasks sensitive to memory. A total of 54.2% of patients were classified as having psychometric impairments across at least two cognitive domains. Twenty-nine patterns were observed, suggesting outcomes in AE are complex. None of the demographic data, clinical features or auxiliary examination variables were predictors of psychometric outcome.
    Conclusions: Cognitive outcomes in AE are complex. Further detailed and standardized cognitive testing, in combination with magnetic resonance imaging volumetrics and serum/cerebrospinal fluid biomarkers, is required to provide rigorous assessments of disease outcomes.
    MeSH term(s) Australia/epidemiology ; Encephalitis/complications ; Encephalitis/epidemiology ; Hashimoto Disease/complications ; Hashimoto Disease/diagnosis ; Humans ; Psychometrics ; Retrospective Studies
    Language English
    Publishing date 2022-05-20
    Publishing country England
    Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 1280785-0
    ISSN 1468-1331 ; 1351-5101 ; 1471-0552
    ISSN (online) 1468-1331
    ISSN 1351-5101 ; 1471-0552
    DOI 10.1111/ene.15367
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Primordium of an artificial Bruch’s membrane made of nanofibers for engineering of retinal pigment epithelium cell monolayers

    Warnke, Patrick H / Alamein, Mohammad / Skabo, Stuart / Stephens, Sebastien / Bourke, Robert / Heiner, Peter / Liu, Qin

    Acta Biomaterialia. 2013 Dec., v. 9, no. 12

    2013  

    Abstract: Transplanted retinal pigment epithelium (RPE) cells hold promise for treatment of age-related macular degeneration (AMD) and Stargardt disease (SD), but it is conceivable that the degenerated host Bruch’s membrane (BM) as a natural substrate for RPE ... ...

    Abstract Transplanted retinal pigment epithelium (RPE) cells hold promise for treatment of age-related macular degeneration (AMD) and Stargardt disease (SD), but it is conceivable that the degenerated host Bruch’s membrane (BM) as a natural substrate for RPE might not optimally support transplanted cell survival with correct cellular organization. We fabricated novel ultrathin three-dimensional (3-D) nanofibrous membranes from collagen type I and poly(lactic-co-glycolic acid) (PLGA) by an advanced clinical-grade needle-free electrospinning process. The nanofibrillar 3-D networks closely mimicked the fibrillar architecture of the native inner collagenous layer of human BM. Human RPE cells grown on our nanofibrous membranes bore a striking resemblance to native human RPE. They exhibited a correctly orientated monolayer with a polygonal cell shape and abundant sheet-like microvilli on their apical surfaces. RPE cells built tight junctions and expressed RPE65 protein. Flat 2-D PLGA film and cover glass as controls delivered inferior RPE layers. Our nanofibrous membranes may imitate the natural BM to such extent that they allow for the engineering of an in vivo-like human RPE monolayer that maintains the natural biofunctional characteristics. Such ultrathin membranes may provide a promising vehicle for a functional RPE cell monolayer implantation in the subretinal space in patients with AMD or SD.
    Keywords cell viability ; collagen ; engineering ; epithelium ; glass ; humans ; macular degeneration ; microvilli ; nanofibers ; patients ; tight junctions
    Language English
    Dates of publication 2013-12
    Size p. 9414-9422.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 2173841-5
    ISSN 1878-7568 ; 1742-7061
    ISSN (online) 1878-7568
    ISSN 1742-7061
    DOI 10.1016/j.actbio.2013.07.029
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Long-term changes in neurocognition and behavior following treatment of sleep disordered breathing in school-aged children.

    Biggs, Sarah N / Vlahandonis, Anna / Anderson, Vicki / Bourke, Robert / Nixon, Gillian M / Davey, Margot J / Horne, Rosemary S C

    Sleep

    2014  Volume 37, Issue 1, Page(s) 77–84

    Abstract: Study objectives: Sleep disordered breathing (SDB) in children is associated with detrimental neurocognitive and behavioral consequences. The long term impact of treatment on these outcomes is unknown. This study examined the long-term effect of ... ...

    Abstract Study objectives: Sleep disordered breathing (SDB) in children is associated with detrimental neurocognitive and behavioral consequences. The long term impact of treatment on these outcomes is unknown. This study examined the long-term effect of treatment of SDB on neurocognition, academic ability, and behavior in a cohort of school-aged children.
    Design: Four-year longitudinal study. Children originally diagnosed with SDB and healthy non-snoring controls underwent repeat polysomnography and age-standardized neurocognitive and behavioral assessment 4y following initial testing.
    Setting: Melbourne Children's Sleep Centre, Melbourne, Australia.
    Participants: Children 12-16 years of age, originally assessed at 7-12 years, were categorized into Treated (N = 12), Untreated (N = 26), and Control (N = 18) groups.
    Interventions: Adenotonsillectomy, Tonsillectomy, Nasal Steroids. Decision to treat was independent of this study.
    Measurements and results: Changes in sleep and respiratory parameters over time were assessed. A decrease in obstructive apnea hypopnea index (OAHI) from Time 1 to Time 2 was seen in 63% and 100% of the Untreated and Treated groups, respectively. The predictive relationship between change in OAHI and standardized neurocognitive, academic, and behavioral scores over time was examined. Improvements in OAHI were predictive of improvements in Performance IQ, but not Verbal IQ or academic measures. Initial group differences in behavioral assessment on the Child Behavior Checklist did not change over time. Children with SDB at baseline continued to exhibit significantly poorer behavior than Controls at follow-up, irrespective of treatment.
    Conclusions: After four years, improvements in SDB are concomitant with improvements in some areas of neurocognition, but not academic ability or behavior in school-aged children.
    MeSH term(s) Adenoidectomy ; Administration, Intranasal ; Aptitude Tests ; Arousal/drug effects ; Child ; Child Behavior/drug effects ; Cognition/drug effects ; Cognition/physiology ; Female ; Humans ; Longitudinal Studies ; Male ; Neuropsychological Tests ; Polysomnography ; Respiration/drug effects ; Sleep/drug effects ; Sleep Apnea Syndromes/complications ; Sleep Apnea Syndromes/physiopathology ; Sleep Apnea Syndromes/psychology ; Sleep Apnea Syndromes/therapy ; Snoring/physiopathology ; Steroids/administration & dosage ; Steroids/pharmacology ; Steroids/therapeutic use ; Time Factors ; Tonsillectomy ; Victoria
    Chemical Substances Steroids
    Language English
    Publishing date 2014-01-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 424441-2
    ISSN 1550-9109 ; 0161-8105
    ISSN (online) 1550-9109
    ISSN 0161-8105
    DOI 10.5665/sleep.3312
    Database MEDical Literature Analysis and Retrieval System OnLINE

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