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  1. Book: Global surveillance, prevention and control of chronic respiratory diseases

    Bousquet, Jean

    a comprehensive approach

    2007  

    Institution Weltgesundheitsorganisation
    Author's details [Jean Bousquet ... ed.]
    Language English
    Size VII, 146 S. : Ill., graph. Darst.
    Publisher WHO
    Publishing place Genf
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT015331211
    ISBN 978-92-4-156346-8 ; 92-4-156346-X
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Online: Rhinitis associated with asthma is distinct from rhinitis alone

    Bousquet, Jean

    The ARIA-MeDALL hypothesis

    2023  

    Abstract: 1169 ... 1203 ... Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of “one-airway-one-disease,” coined over 20 years ago, is a simplistic approach of the links between ...

    Abstract 1169

    1203

    Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of “one-airway-one-disease,” coined over 20 years ago, is a simplistic approach of the links between upper- and lower-airway allergic diseases. With new data, it is time to reassess the concept. This article reviews (i) the clinical observations that led to Allergic Rhinitis and its Impact on Asthma (ARIA), (ii) new insights into polysensitization and multimorbidity, (iii) advances in mHealth for novel phenotype definitions, (iv) confirmation in canonical epidemiologic studies, (v) genomic findings, (vi) treatment approaches, and (vii) novel concepts on the onset of rhinitis and multimorbidity. One recent concept, bringing together upper- and lower-airway allergic diseases with skin, gut, and neuropsychiatric multimorbidities, is the “Epithelial Barrier Hypothesis.” This review determined that the “one-airway-one-disease” concept does not always hold true and that several phenotypes of disease can be defined. These phenotypes include an extreme “allergic” (asthma) phenotype combining asthma, rhinitis, and conjunctivitis. Rhinitis alone and rhinitis and asthma multimorbidity represent two distinct diseases with the following differences: (i) genomic and transcriptomic background (Toll-Like Receptors and IL-17 for rhinitis alone as a local disease; IL-33 and IL-5 for allergic and non-allergic multimorbidity as a systemic disease), (ii) allergen sensitization patterns (mono- or pauci-sensitization versus polysensitization), (iii) severity of symptoms, and (iv) treatment response. In conclusion, rhinitis alone (local disease) and rhinitis with asthma multimorbidity (systemic disease) should be considered as two distinct diseases, possibly modulated by the microbiome, and may be a model for understanding the epidemics of chronic and autoimmune diseases.

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    5
    Keywords asthma ; IL-33 ; multimorbidity ; rhinitis ; Toll-like receptors
    Subject code 610
    Language English
    Publishing country de
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Book: Sublingual immunotherapy: validated!

    Bousquet, Jean

    (Allergy : Supplement ; 81)

    2006  

    Author's details J. Bousquet
    Series title Allergy : Supplement ; 81
    Allergy
    Allergy ; Supplement
    Collection Allergy
    Allergy ; Supplement
    Language English
    Size 31 S. : Ill., graph. Darst.
    Publisher Blackwell Munksgaard
    Publishing place Copenhagen
    Publishing country Denmark
    Document type Book
    HBZ-ID HT014770512
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Rhinitis phenotypes based on multimorbidities.

    Cruz, Álvaro A / Bousquet, Jean

    The journal of allergy and clinical immunology. In practice

    2024  

    Language English
    Publishing date 2024-04-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2024.04.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Nose Woes.

    Naclerio, Robert / Bousquet, Jean

    The journal of allergy and clinical immunology. In practice

    2024  

    Language English
    Publishing date 2024-04-17
    Publishing country United States
    Document type Editorial
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2024.04.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Nebulized beclometasone dipropionate therapy in asthma

    Bousquet, Jean

    (Respiratory medicine ; 97, Suppl. B)

    2003  

    Author's details guest ed. J. Bousquet
    Series title Respiratory medicine ; 97, Suppl. B
    Collection
    Language English
    Size S41 S. : graph. Darst.
    Publisher Saunders
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT013582769
    Database Catalogue ZB MED Medicine, Health

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  7. Book ; Conference proceedings: Quality of life in allergic rhinitis

    Bousquet, Jean

    [Symposium Entitled Quality of Life in Allergic Rhinitis ... held at the European Academy of Allergology and Clinical Immunology annual congress in Lisbon, July 2000]

    (Clinical & experimental allergy reviews ; 2,2)

    2002  

    Event/congress Symposium Entitled Quality of Life in Allergic Rhinitis (2000, Lissabon)
    Author's details guest ed. J. Bousquet
    Series title Clinical & experimental allergy reviews ; 2,2
    Clinical & experimental allergy
    Collection Clinical & experimental allergy
    Language English
    Size S. 55 - 81 : graph. Darst.
    Publisher Blackwell Science
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book ; Conference proceedings
    HBZ-ID HT013386827
    Database Catalogue ZB MED Medicine, Health

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  8. Book ; Conference proceedings: Allergic rhinitis and its impact on asthma

    Bousquet, Jean

    ARIA workshop report

    (The journal of allergy and clinical immunology ; 108,5, Suppl.)

    2001  

    Author's details chair: Jean Bousquet
    Series title The journal of allergy and clinical immunology ; 108,5, Suppl.
    Collection
    Language English
    Size 14A S., S. S147 - S334 : Ill., graph. Darst.
    Publisher Mosby
    Publishing place St. Louis, Mo
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT013235479
    Database Catalogue ZB MED Medicine, Health

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  9. Article ; Online: Staphylococcus aureus Enterotoxin Sensitization Without Aeroallergen Sensitization: An Important Severe Asthma Phenotype.

    Navanandan, Nidhya / Bousquet, Jean

    The journal of allergy and clinical immunology. In practice

    2023  Volume 11, Issue 10, Page(s) 3062–3063

    MeSH term(s) Humans ; Staphylococcus aureus ; Asthma/epidemiology ; Allergens ; Enterotoxins ; Phenotype
    Chemical Substances Allergens ; Enterotoxins
    Language English
    Publishing date 2023-10-05
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2023.08.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book: Emerging therapeutic concepts in asthma management

    Bousquet, Jean

    (Respiratory medicine ; 94, Suppl. D)

    2000  

    Author's details guest ed.: Jean Bousquet
    Series title Respiratory medicine ; 94, Suppl. D
    Collection
    Language English
    Size S43 S. : Ill., graph. Darst.
    Publisher Saunders
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT012823764
    Database Catalogue ZB MED Medicine, Health

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