Article ; Online: Performance Characteristics of Severe Acute Respiratory Syndrome Coronavirus 2 RT-PCR Tests in a Single Health System: Analysis of >10,000 Results from Three Different Assays.
The Journal of molecular diagnostics : JMD
2020 Volume 23, Issue 2, Page(s) 159–163
Abstract: The current pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in the approval of numerous molecular diagnostic assays with various performance and technical capacities. There are limited data comparing performance ... ...
| Abstract | The current pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in the approval of numerous molecular diagnostic assays with various performance and technical capacities. There are limited data comparing performance among assays. We conducted a retrospective analysis of >10,000 test results among three widely used RT-PCR assays for coronavirus disease 2019 (CDC, Simplexa Direct, and TaqPath) to assess performance characteristics. We also retested remnant weakly positive specimens to assess analytical sensitivity. All assays had strong linear correlation and little bias among C |
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| MeSH term(s) | Biological Assay ; COVID-19/diagnosis ; COVID-19/virology ; COVID-19 Testing ; Humans ; Predictive Value of Tests ; Reverse Transcriptase Polymerase Chain Reaction/methods ; SARS-CoV-2/genetics ; SARS-CoV-2/isolation & purification | |||||
| Language | English | |||||
| Publishing date | 2020-12-05 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article | |||||
| ZDB-ID | 2000060-1 | |||||
| ISSN | 1943-7811 ; 1525-1578 | |||||
| ISSN (online) | 1943-7811 | |||||
| ISSN | 1525-1578 | |||||
| DOI | 10.1016/j.jmoldx.2020.11.008 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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