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  1. Article: The effect of the

    Bozkurt, Merve Ayşe / Cesur, Büşra

    Digital health

    2023  Volume 9, Page(s) 20552076231169840

    Abstract: Objective: Family health can be improved by making home visits with mobile applications. This study was carried out to evaluate the effect of a mobile application and web-based software called : Methods: Home visits to 60 mothers in the intervention ... ...

    Abstract Objective: Family health can be improved by making home visits with mobile applications. This study was carried out to evaluate the effect of a mobile application and web-based software called
    Methods: Home visits to 60 mothers in the intervention group, who are over 18 years of age, who have given birth at term, who have no complications in mother and baby, and who are in the second to fifth postpartum days, were made with the online home visits mobile support application Midwifery Home software and their self-efficacy and anxiety levels were evaluated. Mothers were divided into two groups as intervention (60) and control group (60) using a random number table.
    Results: While there was a significant difference between the pretest and posttest self-efficacy levels of the intervention group, there was no difference between the pretest and posttest self-efficacy levels of the control group. When the groups obtained from the Postpartum Specific Anxiety Scale were examined, it was seen that there was a negative and very strong significant relationship between the pretest and posttest scores of the mothers in the intervention group, while when the relationship between the pretest and posttest scores of the mothers in the control group was examined; no significant relationship was observed.
    Conclusion: The practice of
    Language English
    Publishing date 2023-04-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2819396-9
    ISSN 2055-2076
    ISSN 2055-2076
    DOI 10.1177/20552076231169840
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  2. Article ; Online: New Technique of Posterior Fixation of Tube With Fibrin Sealant Prevents Dysphagia in Patients Undergoing Sleeve Gastrectomy.

    Kizilkaya, Mehmet Celal / Bozkurt, Mehmet A

    The American surgeon

    2021  Volume 88, Issue 6, Page(s) 1217–1223

    Abstract: Introduction: This study compared the effects of posterior fixation (PF) of the remnant tube with fibrin tissue glue to prevent sharp angulation and gastric twist and traditional techniques on postoperative dysphagia and vomiting.: Methodology: In ... ...

    Abstract Introduction: This study compared the effects of posterior fixation (PF) of the remnant tube with fibrin tissue glue to prevent sharp angulation and gastric twist and traditional techniques on postoperative dysphagia and vomiting.
    Methodology: In total, 200 patients scheduled to undergo laparoscopic sleeve gastrectomy (LSG) as a bariatric surgical intervention were randomly classified into 2 groups (LSG + PF and LSG alone). We compared postoperative dysphagia symptoms among patients who underwent PF and those who did not. The Dysphagia Handicap Index (DHI) results were compared statistically among these groups.
    Results: The study included a total of 191 patients (85.9% (n = 164) women and 14.1% (n = 27) men) who underwent LSG for obesity. The groups were similar in terms of the patient demographics. The DHI scores of the LSG + PF group were statistically significantly lower than those of the LSG alone group.
    Conclusion: Adoption of a standardized method of PF with a standardized surgical procedure after LSG considerably reduced the rate of surgical complications.
    MeSH term(s) Deglutition Disorders/etiology ; Deglutition Disorders/prevention & control ; Female ; Fibrin Tissue Adhesive/therapeutic use ; Gastrectomy/adverse effects ; Gastrectomy/methods ; Humans ; Laparoscopy/methods ; Male ; Obesity, Morbid/complications ; Obesity, Morbid/surgery ; Postoperative Complications/etiology ; Retrospective Studies ; Treatment Outcome
    Chemical Substances Fibrin Tissue Adhesive
    Language English
    Publishing date 2021-02-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 202465-2
    ISSN 1555-9823 ; 0003-1348
    ISSN (online) 1555-9823
    ISSN 0003-1348
    DOI 10.1177/0003134821991989
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  3. Article ; Online: Factors effecting cecal intubation time during colonoscopy.

    Yilmaz, Serhan / Bolukbasi, Hakan / Bozkurt, Mehmet Abdussamet

    Annali italiani di chirurgia

    2022  Volume 92, Page(s) 665–670

    Abstract: Aim: The aim of this study is to evaluate the factors that has an effect on Cecal Intubation time (CIT), and to define the relationship between quality of bowel preparation and body mass index (BMI).: Patients methods: The Boston Bowel Preparation ... ...

    Abstract Aim: The aim of this study is to evaluate the factors that has an effect on Cecal Intubation time (CIT), and to define the relationship between quality of bowel preparation and body mass index (BMI).
    Patients methods: The Boston Bowel Preparation Scale (BBPS) was used for the evaluation of bowel cleansing. A total of 346 patients were included. The time from anus to caecum was recorded as the time of the cecal intubation time. Patients were defined under 3 subgroup BMI-1; ≤ 24.9, BMI-2; 25-29.9, BMI-3; ≥30.
    Results: The mean BMI of women was 29.30 4.25 and men were 26.19 6.14 (p<0,001). Mean Cecal Intubation time was 9.11 6.00 and 10.21 3.45 minutes for women and men (p=0.012). Women with High BMI (≥30) have shorter Cecal Intubation time compared to women with BMI less than 30 (p=0001). When BBPS evaluated, there was a significant difference in BMI-3 due to high scores compared to both BMI-1 and BMI-2 (p<0.001). In BMI-3 group, also women had significantly higher scores in terms of BBPS(p=0.006). Also a negative correlation between BBPS and BMI with CIT has been found (r = - 0.371, p<0.001 / r = -0.191 p<0.001).
    Conclusion: In our study, women gender and increased BMI has a positive impact on the quality of intestinal cleansing that is associated with shortened Cecal Intubation time.
    Key words: Body Mass Index, Colonoscopy, Cecal intubation.
    MeSH term(s) Body Mass Index ; Cecum ; Colonoscopy ; Female ; Humans ; Male ; Time Factors
    Language English
    Publishing date 2022-02-15
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 418927-9
    ISSN 2239-253X ; 0003-469X
    ISSN (online) 2239-253X
    ISSN 0003-469X
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  4. Article ; Online: Adrenal lesion classification with abdomen caps and the effect of ROI size.

    Solak, Ahmet / Ceylan, Rahime / Bozkurt, Mustafa Alper / Cebeci, Hakan / Koplay, Mustafa

    Physical and engineering sciences in medicine

    2023  Volume 46, Issue 2, Page(s) 865–875

    Abstract: Accurate classification of adrenal lesions on magnetic resonance (MR) images are very important for diagnosis and treatment planning. The detection and classification of lesions in medical imaging heavily rely on several key factors, including the ... ...

    Abstract Accurate classification of adrenal lesions on magnetic resonance (MR) images are very important for diagnosis and treatment planning. The detection and classification of lesions in medical imaging heavily rely on several key factors, including the specialist's level of experience, work intensity, and fatigue of the clinician. These factors are critical determinants of the accuracy and effectiveness of the diagnostic process, which in turn has a direct impact on patient health outcomes. With the spread of artificial intelligence, the use of computer-aided diagnosis (CAD) systems in disease diagnosis has also increased. In this study, adrenal lesion classification was performed using deep learning on MR images. The data set used was obtained from the Department of Radiology, Faculty of Medicine, Selcuk University, and all adrenal lesions were identified and reviewed in consensus by two radiologists experienced with abdominal MR. Studies were carried out on two different data sets created by T1- and T2-weighted MR images. The data set consisted of 112 benign and 10 malignant lesions for each mode. Experiments were performed with regions of interest (ROIs) of different sizes to increase the working performance. Thus, the effect of the selected ROI size on the classification performance was assessed. In addition, instead of the convolutional neural network (CNN) models used in deep learning, a unique classification model structure called Abdomen Caps was proposed. When the data sets used in classification studies are manually separated for training, validation, and testing, different results are obtained with different data sets for each stage. To eliminate this imbalance, tenfold cross-validation was used in this study. The best results obtained were 0.982, 0.999, 0.969, 0.983, 0.998, and 0.964 for accuracy, precision, recall, F1-score, area under the curve (AUC) score, and kappa score, respectively.
    MeSH term(s) Humans ; Deep Learning ; Artificial Intelligence ; Magnetic Resonance Imaging/methods ; Radiology ; Abdomen
    Language English
    Publishing date 2023-04-25
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2662-4737
    ISSN (online) 2662-4737
    DOI 10.1007/s13246-023-01259-y
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  5. Article ; Online: What is the effect of percutaneous cholesistostomy in patients with acute cholecystitis? when is the right time for the procedure?

    Yirgin, Hakan / Topal, Ümmihan / Tatlıdil, Yunusemre / Sibic, Osman / Kizildag Yirgin, Inci / Bozkurt, Mehmet Abdussamet

    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES

    2023  Volume 29, Issue 11, Page(s) 1269–1279

    Abstract: Background: Acute cholecystitis (AC) is one of the most common emergency diseases in surgical practice. Although the gold standard treatment is laparoscopic cholecystectomy, percutaneous cholecystostomy (PC) is performed in some patients due to age, ... ...

    Title translation Akut kolesistitli hastalarda perkütan kolesistostominin etkisi nedir? İşlem için doğru zaman ne zaman?
    Abstract Background: Acute cholecystitis (AC) is one of the most common emergency diseases in surgical practice. Although the gold standard treatment is laparoscopic cholecystectomy, percutaneous cholecystostomy (PC) is performed in some patients due to age, comorbidity, and delays in admission. We aimed to investigate the effect of timing on the clinical process of patients undergoing PC.
    Methods: Patients who underwent PC between February 2017 and December 2021 were included in the study. Those who un-derwent PC in the first 72 h were determined as the early PC group, and those who underwent PC after 72 h were determined as the late PC group. Demographic information of the patients, clinical information before drainage, biochemical values of the first 3 days, length of hospital stay, morbidity and mortality in the early and late period after drainage, and elective cholecystectomy information were recorded. These data were compared between the two groups.
    Results: One hundred and twenty-two patients were included in the study. Early PC was performed in 98 patients (80.3%) and late PC was performed in 24 patients (19.7%). The median follow-up period was 26.6 months (min: 0.25-max: 67) in the early PC group and 26.4 months (min: 0.6-max: 66) in the late PC group (P=0.408). There was no statistically significant difference in mean age, distribu-tion of males and women, concomitant disease, Charlson Comorbidity Index, hepatopancreatobiliary pathology (HPBP), endoscopic retrograde cholangiopancreatography in history and grade (TG18) compared to Tokyo classification (P>0.05). There was no difference between the biochemical parameters (P>0.05). In our study, the median length of hospital stay was 6 (min: 2-max: 36) days in the early PC group, and the median was 9 days (min: 5-max: 20) in the late PC group (P<0.001). A total of 25 patients developed HPBP after PC, 16 of which were AC. There was no statistically significant difference between the early and late PC groups in terms of HPBP develop-ment after PC (P=0.576). There was no statistically significant difference between the early and late PC group in terms of the rate of surgery and type of operation (emergency/elective, open/laparoscopic/conversion, total/subtotal, duration) (P>0.05).
    Conclusion: Discussions about the right timing are ongoing. In our study, we found that patients who underwent early PC had shorter hospital stays. There was no difference between the early and late groups in terms of patient characteristics and severity of AC. PC procedure in AC should be based on algorithms determined by objective data instead of patient-based indications with ran-domized controlled trials.
    MeSH term(s) Male ; Humans ; Female ; Retrospective Studies ; Drainage ; Cholecystostomy/adverse effects ; Cholecystectomy ; Cholecystectomy, Laparoscopic/adverse effects ; Cholecystitis, Acute/surgery ; Cholecystitis, Acute/complications ; Treatment Outcome
    Language English
    Publishing date 2023-10-27
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 2253739-9
    ISSN 1307-7945 ; 1306-696X
    ISSN (online) 1307-7945
    ISSN 1306-696X
    DOI 10.14744/tjtes.2023.40090
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  6. Article: Over-the-scope clip application for severe gastrointestinal bleeding, leak, or perforation: A single-center experience.

    Kocataş, Ali / Somuncu, Erkan / Bozkurt, Mehmet Abdussamet

    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES

    2021  Volume 27, Issue 1, Page(s) 146–150

    Abstract: Background: Over-the-scope clip (OTSC) devices are now widely used by endoscopists for gastrointestinal bleeding, perforation, or leakage. The present study aims to examine the therapeutic success rate of this technique.: Methods: This was a single- ... ...

    Title translation Şiddetli gastrointestinal kanama, kaçak ve perforasyonlar için over-the-scope klip uygulamaları: Tek merkez deneyimi.
    Abstract Background: Over-the-scope clip (OTSC) devices are now widely used by endoscopists for gastrointestinal bleeding, perforation, or leakage. The present study aims to examine the therapeutic success rate of this technique.
    Methods: This was a single-center, retrospective study. In this study, 23 patients with gastrointestinal bleeding, leakage, or perforation were included. The procedure was performed by an experienced endoscopist.
    Results: Of the patients with an upper gastrointestinal tract defect, six had a perforation and there was one case of anastomosis leakage. Eight patients had a perforation in the lower gastrointestinal tract, and there were two cases of anastomosis leakage. Bleeding was detected in only six patients and all of them were upper gastrointestinal bleeding. Anastomosis leaks, perforations, and bleeding were treated with OTSC and additional procedures. The success rate of OTSC clipping alone was 56.5%. However, the success rate was 86.9% with additional therapeutic procedures (clamp, stent, sclerotherapy). Analysis according to categories of bleeding, perforation, and anastomosis leak revealed that the success rate of the clip application in bleeding was significantly higher than that of perforation or anastomosis leak (p=0.002). The median length of stay in the hospital was five days (min-max: 2-30 days). There were no complications associated with the OTSC procedure.
    Conclusion: OTSC is a safe and effective method for the management of gastrointestinal bleeding, perforation, or anastomosis leak.
    MeSH term(s) Anastomotic Leak/surgery ; Endoscopy, Gastrointestinal/instrumentation ; Endoscopy, Gastrointestinal/methods ; Gastrointestinal Hemorrhage/surgery ; Humans ; Intestinal Perforation/surgery ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2021-01-04
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 2253739-9
    ISSN 1306-696X
    ISSN 1306-696X
    DOI 10.14744/tjtes.2020.15719
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  7. Article: Effect of hyperthermic chemotherapy on topical hemostatic agents.

    Altintaş, Tansu / Önalan, N Berrin Dodur / Kızılkaya, Mehmet Celal / Gündüz, Nermin / Bozkurt, Mehmet Abdussamet

    Acta chirurgica Belgica

    2022  Volume 122, Issue 3, Page(s) 164–168

    Abstract: Purpose: There is no clear consensus as to which topical hemostatic agent is best used during cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy. The aim of this study was to evaluate the effect of hyperthermic chemotherapy on ...

    Abstract Purpose: There is no clear consensus as to which topical hemostatic agent is best used during cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy. The aim of this study was to evaluate the effect of hyperthermic chemotherapy on the biomechanical properties of organic topical hemostatic agents and histologically fibrin formation rates.
    Methods: Four topical hemostatic agents (Spongostan™, Surgicel
    Results: There were no statistically significant differences according to strength and flexibility of topical hemostatic agents on hyperthermic chemotherapy. Histopathologically, the highest fibrin formation was observed in Surgicel
    Conclusions: This study demonstrated that exposure to hyperthermic chemotherapy did not significantly affect the biomechanical properties of organic topical hemostatic agents and the fibrin clot formation.
    MeSH term(s) Cisplatin ; Combined Modality Therapy ; Cytoreduction Surgical Procedures ; Fibrin/pharmacology ; Hemostasis ; Hemostatics/therapeutic use ; Humans ; Hyperthermia, Induced
    Chemical Substances Hemostatics ; Fibrin (9001-31-4) ; Cisplatin (Q20Q21Q62J)
    Language English
    Publishing date 2022-01-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 210274-2
    ISSN 0001-5458
    ISSN 0001-5458
    DOI 10.1080/00015458.2021.1888199
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  8. Article ; Online: Impact of COVID-19 pandemic on colonoscopy results - an overview.

    Bozdağ, Emre / Somuncu, Erkan / Ozcan, Adem / Devecioğlu, Elif Gökçe / Gülmez, Selçuk / Bozkurt, Mehmet Abdussamet

    Polski przeglad chirurgiczny

    2022  Volume 94, Issue 4, Page(s) 15–19

    Abstract: ... Aim: ... Colorectal cancers are common cancers. Colonoscopy procedure, which is applied in the early diagnosis and treatment of this disease, has a very important role. In this study, we aimed to examine the effect of the COVİD-19 pandemic period on ... ...

    Abstract Aim: Colorectal cancers are common cancers. Colonoscopy procedure, which is applied in the early diagnosis and treatment of this disease, has a very important role. In this study, we aimed to examine the effect of the COVİD-19 pandemic period on our colonoscopic procedures.

    Material and methods: In this observational study, the data of the patients who underwent colonoscopy in our General Surgery Endoscopy Unit, between March 11, 2019 and March 12, 2021 were scanned retrospectively. Patients under 18 years of age were excluded. The patients were divided into 2 groups. 1. Group patients between 11 March 2019-11 March 2020; patients in the pre-COVID-19 period, Group 2, on March 12, 2020-March 12, 2021; Grouped as the COVID-19 era.

    Results: Data of 8285 patients were analyzed. A total of 4889 patients in Group 1 and 3396 patients in Group 2 were included in the study. The detection of precancerous polyps between the groups was found to be significantly higher in group 1 (p < 0.05) (4.3% vs 2.1). Similarly, the presence of precancerous polyps over the age of 65 was found to be significantly higher in the pre-covid group. In group 1, no significant difference was found in the evaluation of cancer patients according to gender (p > 0.05) (F/M: 1.2%/1.6%). In group 2, cancer patients were found to be significantly higher in males.

    Conclusions: The COVİD-19 pandemic has had negative effects in many areas, as well as on our colonoscopic procedures. Experienced centers continue to work to minimize these negative effects.
    MeSH term(s) Adolescent ; COVID-19/epidemiology ; Colonoscopy ; Humans ; Male ; Pandemics ; Precancerous Conditions ; Retrospective Studies
    Language English
    Publishing date 2022-09-01
    Publishing country Poland
    Document type Journal Article ; Observational Study
    ZDB-ID 128732-1
    ISSN 2299-2847 ; 0032-373X
    ISSN (online) 2299-2847
    ISSN 0032-373X
    DOI 10.5604/01.3001.0015.7299
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  9. Article ; Online: Extrahepatic Biliary Tract Variations is an Effect for Acute Calculous Cholecystitis.

    Bozdag, Emre / Sonmez, Suleyman / Somuncu, Erkan / Yilmaz, Serhan / Basaran, Ceren / Bozkurt, Mehmet Abdussamet

    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

    2022  Volume 32, Issue 8, Page(s) 991–995

    Abstract: Objective: To evaluate the anatomy of the extrahepatic bile duct and to reveal its importance in the formation of acute calculous cholecystitis (ACC).: Study design: Case-control study.: Place and duration of study: Department of General Surgery ... ...

    Abstract Objective: To evaluate the anatomy of the extrahepatic bile duct and to reveal its importance in the formation of acute calculous cholecystitis (ACC).
    Study design: Case-control study.
    Place and duration of study: Department of General Surgery and Radiology, Kanuni Sultan Suleyman Training and Research Hospital of the University of Health Sciences, Turkey, between January 2016 and December 2021.
    Methodology: The data of the patients treated with ACC were analysed on MRCP by an experienced radiologist. The patients were divided into two groups; asymptomatic gallstones (AsGS, control group) and ACC. The cystic duct, common hepatic duct, and common bile duct lengths and variations in cystic duct opening were measured. Receiver operating characteristics (ROC) analysis was conducted to define a cut-off value and compared categorical results of the two groups by Mann-Whitney U test.
    Results: One-hundred and seventy-three patients were analysed, one-hundred and seven were females, and 66 were males. The median age was 46 years in the AsGS group and 53 years in the ACC group. It was statistically significant that ACC had a higher median age value than AsGS (p=0.014). In the analysis of extrahepatic variations, cystic duct, common hepatic duct, and common bile duct length, were statistically longer in the calculous cholecystitis group (p<0.001, p=0.022, and p=0.019 respectively). ROC analysis was performed for cystic, common hepatic, and common bile duct length, respectively. Cut-off values ​​were 30.5 mm, 36.5 mm, and 42.5 mm.
    Conclusion: Extrahepatic bile duct variations are of critical importance in ACC surgery. In the data, as the cystic duct and common bile duct lengthens, the possibility of ACC increases. There is need for studies with larger samples.
    Key words: Acute calculous cholecystitis, Extrahepatic biliary tract, Anatomical variations, Cholelithiasis.
    MeSH term(s) Bile Ducts, Extrahepatic/diagnostic imaging ; Case-Control Studies ; Cholecystitis/diagnostic imaging ; Cholecystitis/surgery ; Cholecystitis, Acute/diagnostic imaging ; Cholecystitis, Acute/surgery ; Cystic Duct/diagnostic imaging ; Female ; Gallstones/complications ; Gallstones/diagnostic imaging ; Gallstones/surgery ; Humans ; Male ; Middle Aged
    Language English
    Publishing date 2022-08-06
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 2276646-7
    ISSN 1681-7168 ; 1022-386X
    ISSN (online) 1681-7168
    ISSN 1022-386X
    DOI 10.29271/jcpsp.2022.08.991
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  10. Article ; Online: Impact of positive-to-total lymph node ratio on prognosis in stage 3 colorectal cancer. A multicenter study.

    Yirgin, Hakan / Sibic, Osman / Aziret, Mehmet / Tatlidil, Yunusemre / Devecioglu, Elif Gokce / Bozkurt, Mehmet Abdussamet / Ercan, Metin

    Annali italiani di chirurgia

    2023  Volume 94, Page(s) 375–383

    Abstract: Background: Colorectal cancer remains a health problem despite advances in diagnostic and treatment methods. This study aimed to determine the impact of positive-to-total lymph node ratio on survival in colorectal cancer.: Methods: Patients with ... ...

    Abstract Background: Colorectal cancer remains a health problem despite advances in diagnostic and treatment methods. This study aimed to determine the impact of positive-to-total lymph node ratio on survival in colorectal cancer.
    Methods: Patients with stage 3 colorectal cancer were included. Patients age; sex; operation type (emergency or elective); tumor size, grade, and location; TNM stage; vascular and perineural invasions; numbers of lymph nodes examined and negative lymph nodes, positive-to-total lymph node ratio, and administration of postoperative chemotherapy were examined.
    Results: Median follow-up period was 34.7 months. Most patients were in stage 3b (67.9%), and the median number of dissected lymph nodes was 15. The number of metastatic lymph nodes, positive lymph node ratio, and negativeto- positive lymph node ratio were 3, 16.7, 11, and 5, respectively. The overall survival rate was 48.6%. Mean life expectancy was 51.5 months. Multivariate Cox regression analysis revealed positive-to-total lymph node ratio >23.3%, age, and absence of postoperative chemotherapy as risk factors for overall survival (p<0.05). Positive-to-total lymph node ratio >23.3% was associated with poor overall survival and 3.726-fold poorer survival.
    Discussion: Positive-to-total lymph node ratio >23.3% is a risk factor affecting overall survival in stage 3 colorectal cancer. Increased positive-to-total lymph node ratio (>23.3%) is associated with poor overall survival.
    Key words: Colorectal Cancer, Overall Survival, Positive Lymph Node Ratio, Stage 3 Cancer.
    MeSH term(s) Humans ; Colorectal Neoplasms/pathology ; Lymph Node Excision ; Lymph Node Ratio ; Lymph Nodes/pathology ; Lymphatic Metastasis/pathology ; Neoplasm Staging ; Prognosis ; Retrospective Studies ; Male ; Female
    Language English
    Publishing date 2023-10-04
    Publishing country Italy
    Document type Multicenter Study ; Journal Article
    ZDB-ID 418927-9
    ISSN 2239-253X ; 0003-469X
    ISSN (online) 2239-253X
    ISSN 0003-469X
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