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  1. Article ; Online: Absence of Nosocomial Transmission of Imported Lassa Fever during Use of Standard Barrier Nursing Methods.

    Grahn, Anna / Bråve, Andreas / Tolfvenstam, Thomas / Studahl, Marie

    Emerging infectious diseases

    2018  Volume 24, Issue 6, Page(s) 978–987

    Abstract: Nosocomial transmission of Lassa virus (LASV) is reported to be low when care for the index patient includes proper barrier nursing methods. We investigated whether asymptomatic LASV infection occurred in healthcare workers who used standard barrier ... ...

    Abstract Nosocomial transmission of Lassa virus (LASV) is reported to be low when care for the index patient includes proper barrier nursing methods. We investigated whether asymptomatic LASV infection occurred in healthcare workers who used standard barrier nursing methods during the first 15 days of caring for a patient with Lassa fever in Sweden. Of 76 persons who were defined as having been potentially exposed to LASV, 53 provided blood samples for detection of LASV IgG. These persons also responded to a detailed questionnaire to evaluate exposure to different body fluids from the index patient. LASV-specific IgG was not detected in any of the 53 persons. Five of 53 persons had not been using proper barrier nursing methods. Our results strengthen the argument for a low risk of secondary transmission of LASV in humans when standard barrier nursing methods are used and the patient has only mild symptoms.
    MeSH term(s) Adult ; Aged ; Communicable Diseases, Imported/epidemiology ; Communicable Diseases, Imported/transmission ; Communicable Diseases, Imported/virology ; Cross Infection/epidemiology ; Cross Infection/transmission ; Cross Infection/virology ; Female ; Health Personnel ; Humans ; Lassa Fever/epidemiology ; Lassa Fever/transmission ; Lassa Fever/virology ; Lassa virus/classification ; Lassa virus/genetics ; Lassa virus/immunology ; Male ; Middle Aged ; Nursing Care/methods ; Sentinel Surveillance ; Sweden/epidemiology
    Language English
    Publishing date 2018-05-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1380686-5
    ISSN 1080-6059 ; 1080-6040
    ISSN (online) 1080-6059
    ISSN 1080-6040
    DOI 10.3201/eid2406.172097
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4778: Show issues Location:
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  2. Article ; Online: Infection Rate of SARS-CoV-2 in Asymptomatic Healthcare Workers, Sweden, June 2022.

    Blom, Kim / Havervall, Sebastian / Marking, Ulrika / Norin, Nina Greilert / Bacchus, Philip / Groenheit, Ramona / Bråve, Andreas / Thålin, Charlotte / Klingström, Jonas

    Emerging infectious diseases

    2022  Volume 28, Issue 10, Page(s) 2119–2121

    Abstract: Given the recent surge in SARS-CoV-2 Omicron infections, we performed a quantitative PCR screening survey during June 28-29, 2022, in Stockholm, Sweden, to investigate SARS-CoV-2 point prevalence in a group with high exposure risk. Results showed SARS- ... ...

    Abstract Given the recent surge in SARS-CoV-2 Omicron infections, we performed a quantitative PCR screening survey during June 28-29, 2022, in Stockholm, Sweden, to investigate SARS-CoV-2 point prevalence in a group with high exposure risk. Results showed SARS-CoV-2 infection in 2.3% of healthcare workers who were asymptomatic at time of sampling.
    MeSH term(s) COVID-19/epidemiology ; COVID-19 Testing ; Health Personnel ; Humans ; SARS-CoV-2 ; Sweden/epidemiology
    Language English
    Publishing date 2022-08-23
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 1380686-5
    ISSN 1080-6059 ; 1080-6040
    ISSN (online) 1080-6059
    ISSN 1080-6040
    DOI 10.3201/eid2810.221093
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4778: Show issues Location:
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  3. Article ; Online: Civil-Military Collaboration to Facilitate Rapid Deployment of a Mobile Laboratory in Early Response to COVID-19: A High-Readiness Exercise.

    Bacchus, Philip / Nissen, Karolina / Berg, Johanna / Bråve, Andreas / Gyll, Jenny / Larsson, Christer / Muradrasoli, Shaman / Tellström, Andreas / Salaneck, Erik

    Health security

    2021  Volume 19, Issue 5, Page(s) 488–497

    Abstract: Rapid and adaptable diagnostic capabilities are of great importance in the face of emerging infectious diseases. In an outbreak, timely establishment of diagnostic routines is crucial to identifying cases and preventing the spread of the disease, ... ...

    Abstract Rapid and adaptable diagnostic capabilities are of great importance in the face of emerging infectious diseases. In an outbreak, timely establishment of diagnostic routines is crucial to identifying cases and preventing the spread of the disease, especially when faced with high-consequence pathogens. In this article, we describe a multiagency exercise including the rapid deployment and diagnostic adaptation of the Swedish Armed Forces mobile laboratory (biological field analysis laboratory) in the context of COVID-19. This deployment was initiated as a high-readiness exercise at the end of January 2020, when the global development of the outbreak was still uncertain. Through collaboration with the Public Health Agency of Sweden and a civilian hospital, a real-time reverse transcriptase polymerase chain reaction method specific to SARS-CoV-2 was made available and adapted to the mobile laboratory, and the team established and evaluated a functional and efficient diagnostic asset along with a logistical support chain. We also organized and evaluated mobile testing teams, and the method was later used in large-scale, national, cross-sectional COVID-19 surveys in several regions of Sweden. In this article, we focus on the challenges of overbridging the civil-military interface in this context and identifying lessons learned and added values to the response during the early pandemic. We propose that the experiences from this exercise and governmental agency collaboration are valuable in preparation for future outbreaks.
    MeSH term(s) COVID-19 ; Cross-Sectional Studies ; Humans ; Laboratories ; Military Personnel ; SARS-CoV-2
    Language English
    Publishing date 2021-09-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2823049-8
    ISSN 2326-5108 ; 2326-5094
    ISSN (online) 2326-5108
    ISSN 2326-5094
    DOI 10.1089/hs.2021.0011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Long-Lasting Mucosal and Systemic Immunity against Influenza A Virus Is Significantly Prolonged and Protective by Nasal Whole Influenza Immunization with Mucosal Adjuvant N3 and DNA-Plasmid Expressing Flagellin in Aging In- and Outbred Mice.

    Hinkula, Jorma / Nyström, Sanna / Devito, Claudia / Bråve, Andreas / Applequist, Steven E

    Vaccines

    2019  Volume 7, Issue 3

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2019-07-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines7030064
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Retrospective meta-transcriptomic identification of severe dengue in a traveller returning from Africa to Sweden, 1990

    Alfsnes, Kristian / Lagerqvist, Nina / Vene, Sirkka / Bohlin, Jon / Verner-Carlsson, Jenny / Ekqvist, David / Bråve, Andreas / Holmes, Edward C / Shi, Weifeng / Pettersson, John H.-O

    One health. 2021 June, v. 12

    2021  

    Abstract: Pathogens associated with haemorrhagic fever commonly have zoonotic origins. The first documented imported case of likely viral severe haemorrhagic fever in Sweden occurred in 1990. Despite extensive study, no aetiological agent was identified. Following ...

    Abstract Pathogens associated with haemorrhagic fever commonly have zoonotic origins. The first documented imported case of likely viral severe haemorrhagic fever in Sweden occurred in 1990. Despite extensive study, no aetiological agent was identified. Following retrospective investigation with total RNA-sequencing of samples collected between 7 and 36 days from onset of symptoms we identified dengue virus 3 (DENV-3) and a human pegivirus (HPgV). We conclude that the patient likely suffered from haemorrhagic symptoms due to an atypical severe and undiagnosed dengue infection.
    Keywords Dengue virus ; Pegivirus ; dengue ; fever ; humans ; patients ; sequence analysis ; Africa ; Sweden
    Language English
    Dates of publication 2021-06
    Publishing place Elsevier B.V.
    Document type Article
    Note NAL-light
    ZDB-ID 2834831-X
    ISSN 2352-7714
    ISSN 2352-7714
    DOI 10.1016/j.onehlt.2021.100217
    Database NAL-Catalogue (AGRICOLA)

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  6. Article ; Online: High Prevalence of SARS-CoV-2 Omicron Infection Despite High Seroprevalence, Sweden, 2022.

    Groenheit, Ramona / Bacchus, Philip / Galanis, Ilias / Sondén, Klara / Bujila, Ioana / Efimova, Tatiana / Garli, Fredrik / Lindsjö, Oskar Karlsson / Mansjö, Mikael / Movert, Elin / Pettke, Aleksandra / Rapp, Marie / Sperk, Maike / Söderholm, Sandra / Asin, Karin Valentin / Zanetti, Sarah / Karlberg, Maria Lind / Bråve, Andreas / Blom, Kim /
    Klingström, Jonas

    Emerging infectious diseases

    2023  Volume 29, Issue 6, Page(s) 1240–1243

    Abstract: We performed 2 surveys during 2022 to estimate point prevalences of SARS-CoV-2 infection compared with overall seroprevalence in Sweden. Point prevalence was 1.4% in March and 1.5% in September. Estimated seroprevalence was >80%, including among ... ...

    Abstract We performed 2 surveys during 2022 to estimate point prevalences of SARS-CoV-2 infection compared with overall seroprevalence in Sweden. Point prevalence was 1.4% in March and 1.5% in September. Estimated seroprevalence was >80%, including among unvaccinated children. Continued SARS-CoV-2 surveillance is necessary for detecting emerging, possibly more pathogenic variants.
    MeSH term(s) Child ; Humans ; COVID-19/epidemiology ; Prevalence ; SARS-CoV-2 ; Sweden/epidemiology ; Seroepidemiologic Studies
    Language English
    Publishing date 2023-05-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1380686-5
    ISSN 1080-6059 ; 1080-6040
    ISSN (online) 1080-6059
    ISSN 1080-6040
    DOI 10.3201/eid2906.221862
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4778: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  7. Article: Draft Genome Sequence of Strain R13-38 from a Francisella tularensis Outbreak in Sweden.

    Alm, Erik / Advani, Abdolreza / Bråve, Andreas / Wahab, Tara

    Genome announcements

    2015  Volume 3, Issue 1

    Abstract: We have whole-genome sequenced a Francisella tularensis subsp. holarctica (also known as type B) strain from an outbreak in Sweden in 2013, derived from a privately owned well for drinking water. ...

    Abstract We have whole-genome sequenced a Francisella tularensis subsp. holarctica (also known as type B) strain from an outbreak in Sweden in 2013, derived from a privately owned well for drinking water.
    Language English
    Publishing date 2015-02-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2704277-7
    ISSN 2169-8287
    ISSN 2169-8287
    DOI 10.1128/genomeA.01517-14
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Assessment of biorisk management systems in high containment laboratories, 18 countries in Europe, 2016 and 2017.

    Appelt, Sandra / Jacob, Daniela / Rohleder, Anna-Maria / Bråve, Andreas / Szekely Björndal, Åsa / Di Caro, Antonino / Grunow, Roland

    Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

    2020  Volume 25, Issue 36

    Abstract: Europe-wide activities to improve biosafety and biosecurity performed within the frameworks of the European Union (EU)-funded Joint Actions EMERGE and QUANDHIP led to the development of an Integrated European Checklist for Laboratory Biorisk Management ( ... ...

    Abstract Europe-wide activities to improve biosafety and biosecurity performed within the frameworks of the European Union (EU)-funded Joint Actions EMERGE and QUANDHIP led to the development of an Integrated European Checklist for Laboratory Biorisk Management (ECL).To better understand different approaches shaping biorisk management (BRM) systems on an operational level in high containment laboratories, the ECL was used to map the implementation of BRM in 32 high containment laboratories in 18 countries in Europe. The results suggest that the BRM elements referring to standard microbiological working practices and the handling of infectious material were fulfilled particularly well. The elements safety exercises involving internal and external emergency responders, and appropriate decommissioning plans were not fulfilled particularly well. BRM in Biosafety Level (BSL) 4 laboratories handling Risk Group (RG) 4 viruses appear to vary among each other less than BSL3 laboratories handling RG 3 bacteria. It is important to agree on comparable regulations in Europe as high containment laboratories are indispensable for a safe, quick and effective response to public health threats. As high containment laboratories may also present a public health risk it is crucial to have robust BRM on organisational and operational levels.
    MeSH term(s) Communicable Disease Control/methods ; Containment of Biohazards/methods ; Containment of Biohazards/standards ; European Union ; Humans ; Laboratories/organization & administration ; Safety Management/methods ; Safety Management/organization & administration ; Safety Management/standards
    Language English
    Publishing date 2020-10-28
    Publishing country Sweden
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1338803-4
    ISSN 1560-7917 ; 1025-496X
    ISSN (online) 1560-7917
    ISSN 1025-496X
    DOI 10.2807/1560-7917.ES.2020.25.36.2000089
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5066: Show issues Location:
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  9. Article: Retrospective meta-transcriptomic identification of severe dengue in a traveller returning from Africa to Sweden, 1990.

    Alfsnes, Kristian / Lagerqvist, Nina / Vene, Sirkka / Bohlin, Jon / Verner-Carlsson, Jenny / Ekqvist, David / Bråve, Andreas / Holmes, Edward C / Shi, Weifeng / Pettersson, John H-O

    One health (Amsterdam, Netherlands)

    2021  Volume 12, Page(s) 100217

    Abstract: Pathogens associated with haemorrhagic fever commonly have zoonotic origins. The first documented imported case of likely viral severe haemorrhagic fever in Sweden occurred in 1990. Despite extensive study, no aetiological agent was identified. Following ...

    Abstract Pathogens associated with haemorrhagic fever commonly have zoonotic origins. The first documented imported case of likely viral severe haemorrhagic fever in Sweden occurred in 1990. Despite extensive study, no aetiological agent was identified. Following retrospective investigation with total RNA-sequencing of samples collected between 7 and 36 days from onset of symptoms we identified dengue virus 3 (DENV-3) and a human pegivirus (HPgV). We conclude that the patient likely suffered from haemorrhagic symptoms due to an atypical severe and undiagnosed dengue infection.
    Language English
    Publishing date 2021-01-22
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2834831-X
    ISSN 2352-7714
    ISSN 2352-7714
    DOI 10.1016/j.onehlt.2021.100217
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Seroprevalence of SARS-CoV-2 in Sweden, April 26 to May 9, 2021.

    Beser, Jessica / Galanis, Ilias / Enkirch, Theresa / Kühlmann Berenzon, Sharon / van Straten, Edward / Duracz, Jan / Rapp, Marie / Zakikhany, Katherina / Mansjö, Mikael / Wigren Byström, Julia / Forsell, Mattias N E / Groenheit, Ramona / Tegmark Wisell, Karin / Bråve, Andreas

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 10816

    Abstract: A national point seroprevalence study of SARS-CoV-2 was conducted in Sweden in April-May 2021. In total, 2860 individuals 3 to 90 years old from a probability-based web panel were included. Results showed that an estimated 32.6% of the population in ... ...

    Abstract A national point seroprevalence study of SARS-CoV-2 was conducted in Sweden in April-May 2021. In total, 2860 individuals 3 to 90 years old from a probability-based web panel were included. Results showed that an estimated 32.6% of the population in Sweden had detectable levels of antibodies, and among non-vaccinated 20.1% had detectable levels of antibodies. We tested for differences in seroprevalence between age groups and by sex and estimated seroprevalence among previously infected participants by time since reporting.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antibodies, Viral ; COVID-19/epidemiology ; Child ; Child, Preschool ; Humans ; Immunoglobulin G ; Middle Aged ; SARS-CoV-2 ; Seroepidemiologic Studies ; Sweden/epidemiology ; Young Adult
    Chemical Substances Antibodies, Viral ; Immunoglobulin G
    Language English
    Publishing date 2022-06-25
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-15183-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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