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Article: Exposure to continuous bromodeoxyuridine (BrdU) differentially affects cell cycle progression of human breast and bladder cancer cell lines.

Diermeier, S / Schmidt-Bruecken, E / Kubbies, M / Kunz-Schughart, L A / Brockhoff, G

2004 Volume 37, Issue 2, Page(s) 195–206

Abstract: Incorporation of bromodeoxyuridine (BrdU) during DNA replication is frequently used for cell cycle analysis. The flow cytometric BrdU/Hoechst quenching technique is conducive to high-resolution assessment of cell cycle kinetics, but requires continuous ... ...

Abstract	Incorporation of bromodeoxyuridine (BrdU) during DNA replication is frequently used for cell cycle analysis. The flow cytometric BrdU/Hoechst quenching technique is conducive to high-resolution assessment of cell cycle kinetics, but requires continuous BrdU treatment, which may have cytostatic or cytotoxic effects. Here, we have examined the impact of BrdU on the proliferation of BT474 and SK-BR-3 breast cancer cell lines and compared the observed effects with cell proliferation of RT4 and J82 bladder carcinoma cells, previously described to be sensitive and insensitive to BrdU, respectively. Both uni- and bi-parametric DNA measurements were performed to identify BrdU-induced alterations in the S-phase fraction and in cell cycle progression. An annexinV/propidium iodide (PI) assay was used to identify potential induction of apoptosis by BrdU. Proliferative activity in BT474, SK-BR-3, and RT4 cultures was reduced in different cell cycle phases due to continuous treatment with 60, 5.0, and 3.5 micro m BrdU. This effect, which was not found in J82 cultures, was dependent on exposure time (96 versus 48 h) and was also dose-dependent for RT4 and SK-BR-3. BrdU application does not induce apoptosis or necrosis as revealed with the annexin V/PI assay. We concluded that continuous BrdU treatment did not affect cell viability, but essentially alters cell cycle progression in three out of four cell lines tested. Cell-type specific validation of the feasibility of the powerful BrdU/Hoechst quenching technique is required and recommended.
MeSH term(s)	Apoptosis/drug effects ; Apoptosis/genetics ; Breast Neoplasms/drug therapy ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Bromodeoxyuridine/toxicity ; Carcinoma/drug therapy ; Carcinoma/genetics ; Carcinoma/pathology ; Cell Cycle/drug effects ; Cell Cycle/genetics ; Cell Line, Tumor ; Cell Survival/drug effects ; Cell Survival/genetics ; Cytogenetic Analysis/methods ; DNA/analysis ; DNA/genetics ; DNA Replication/drug effects ; DNA Replication/genetics ; Dose-Response Relationship, Drug ; Female ; Flow Cytometry/methods ; Humans ; Male ; Prostatic Neoplasms/drug therapy ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms/pathology ; Reproducibility of Results
Chemical Substances	DNA (9007-49-2) ; Bromodeoxyuridine (G34N38R2N1)
Language	English
Publishing date	2004-04
Publishing country	England
Document type	Comparative Study ; Journal Article
ZDB-ID	1064202-x
ISSN	1365-2184 ; 0960-7722 ; 0008-8730
ISSN (online)	1365-2184
ISSN	0960-7722 ; 0008-8730
DOI	10.1111/j.1365-2184.2004.00296.x
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Article: Differential impact of Cetuximab, Pertuzumab and Trastuzumab on BT474 and SK-BR-3 breast cancer cell proliferation.

Brockhoff, G / Heckel, B / Schmidt-Bruecken, E / Plander, M / Hofstaedter, F / Vollmann, A / Diermeier, S

Cell proliferation

2007 Volume 40, Issue 4, Page(s) 488–507

Abstract: Objectives: The potential of epidermal growth factor receptor (EGFR)- and Her2-targeted antibodies Cetuximab, Pertuzumab and Trastuzumab, used in combination to inhibit cell proliferation of breast cancer cells in vitro, has not been extensively ... ...

Abstract	Objectives: The potential of epidermal growth factor receptor (EGFR)- and Her2-targeted antibodies Cetuximab, Pertuzumab and Trastuzumab, used in combination to inhibit cell proliferation of breast cancer cells in vitro, has not been extensively investigated. It is anticipated that there would be differences between specific erbB receptor co-expression profiles that would affect tumour cell growth. Materials and methods: We have examined the effects of Cetuximab, Pertuzumab and Trastuzumab, applied separately or in combination, on cell proliferation of BT474 and SK-BR-3 breast cancer cell lines. Cell cycle progression of BT474 and SK-BR-3 cells was statically and dynamically assessed using flow cytometry. In order to discover a potential influence of differential EGFR co-expression on sensitivity to antibody treatment, EGFR was down-regulated by siRNA in SK-BR-3. An annexinV/propidium iodide assay was used to identify potential induction of apoptosis. Results: Treatment with Pertuzumab and Trastuzumab, both targeted to Her2, resulted in a reduced fraction of proliferating cells, prolongation of G(1) phase and a great increase in quiescent BT474 cells. Cetuximab had no additional contribution to the effect of either Pertuzumab or Trastuzumab when administered simultaneously. Treatment with the antibodies did not induce an appreciable amount of apoptosis in either BT474 or SK-BR-3 cells. In contrast to SK-BR-3, the BT474 cell line appears to be more sensitive to antibody treatment due to low EGFR content besides Her2 overexpression. Conclusion: The extent of decelerated or blocked cell proliferation after antibody treatment that is targeted to EGFR and to Her2 depends both on EGFR and Her2 co-expression and on antibody combination used in the treatment setting. Cetuximab did not enhance any inhibitory effect of Trastuzumab or Pertuzumab, most probably due to the dominant overexpression of Her2. Cell susceptibility to Trastuzumab/Pertuzumab, both targeted to Her2, was defined by the ratio of EGFR/Her2 co-expression.
MeSH term(s)	Antibodies, Monoclonal/therapeutic use ; Antibodies, Monoclonal, Humanized ; Antineoplastic Agents/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Apoptosis ; Benzimidazoles ; Breast Neoplasms/drug therapy ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Bromodeoxyuridine/analysis ; Cell Cycle ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cetuximab ; ErbB Receptors/antagonists & inhibitors ; ErbB Receptors/genetics ; ErbB Receptors/metabolism ; Fluorescent Dyes ; Humans ; Ki-67 Antigen/analysis ; RNA Interference ; S Phase ; Trastuzumab
Chemical Substances	Antibodies, Monoclonal ; Antibodies, Monoclonal, Humanized ; Antineoplastic Agents ; Benzimidazoles ; Fluorescent Dyes ; Ki-67 Antigen ; hoechst 32258 ; ErbB Receptors (EC 2.7.10.1) ; Bromodeoxyuridine (G34N38R2N1) ; pertuzumab (K16AIQ8CTM) ; Trastuzumab (P188ANX8CK) ; Cetuximab (PQX0D8J21J)
Language	English
Publishing date	2007-08
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1064202-x
ISSN	1365-2184 ; 0960-7722 ; 0008-8730
ISSN (online)	1365-2184
ISSN	0960-7722 ; 0008-8730
DOI	10.1111/j.1365-2184.2007.00449.x
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Article ; Online: Multichromatic phenotyping of HER receptor coexpression in breast tumor tissue samples using flow cytometry--possibilities and limitations.

Vollmann-Zwerenz, Arabel / Diermeier-Daucher, Simone / Wege, Anja Kathrin / Sassen, Andrea / Schmidt-Brücken, Elisabeth / Hofstaedter, Ferdinand / Ortmann, Olaf / Nauwelaers, Frans / Brockhoff, Gero

Cytometry. Part A : the journal of the International Society for Analytical Cytology

2010 Volume 77, Issue 4, Page(s) 387–398

Abstract: The prognostic significance of HER2 expression in human breast carcinomas is beyond dispute nowadays. The HER family of receptor tyrosine kinases comprises four members (HER1/ErbB1/EGFR, HER2/ErbB2, HER3/ErbB3, and HER4/ErbB4) that act in concert via ... ...

Abstract	The prognostic significance of HER2 expression in human breast carcinomas is beyond dispute nowadays. The HER family of receptor tyrosine kinases comprises four members (HER1/ErbB1/EGFR, HER2/ErbB2, HER3/ErbB3, and HER4/ErbB4) that act in concert via transactivation and consequently compose a functional signaling unit. Besides HER2 overexpression, coexpression of other HER receptors has substantial impact on course of disease and potential therapeutic benefit. This observation is substantiated by numerous preclinical studies and retrospective studies done on patients with breast cancer. Against this background, the quantification of all HER receptor expressions at the same time would significantly extend the information content revealed by routine diagnosis of breast cancer tissues. Moreover, the knowledge of HER receptor coexpression profiles in primary tumor samples could provide the basis to design and develop highly specific antireceptor treatment strategies. Here, we report on a simultaneous flow cytometric detection of all four HER receptors on carcinoma cells isolated from primary breast cancer tissues and separated from nonepithelial cells by cytokeratin staining. Combined with DNA, i.e. ploidy quantification, the approach resulted in a six-parameter assay that could complement the diagnosis of a variety of diseases in which HER receptor expression has a pivotal impact on the degree of malignancy.
MeSH term(s)	Animals ; Antibody Specificity/immunology ; Blotting, Western ; Breast Neoplasms/diagnosis ; Breast Neoplasms/enzymology ; Breast Neoplasms/pathology ; Cell Line, Tumor ; DNA, Neoplasm/metabolism ; Female ; Flow Cytometry/methods ; Humans ; Mice ; NIH 3T3 Cells ; Phenotype ; Receptor Protein-Tyrosine Kinases/metabolism ; Staining and Labeling
Chemical Substances	DNA, Neoplasm ; Receptor Protein-Tyrosine Kinases (EC 2.7.10.1)
Language	English
Publishing date	2010-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	2099868-5
ISSN	1552-4930 ; 0196-4763 ; 1552-4922
ISSN (online)	1552-4930
ISSN	0196-4763 ; 1552-4922
DOI	10.1002/cyto.a.20868
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Article ; Online: Luminosity-independent measurement of the proton-proton total cross section at √s=8 TeV.

Antchev, G / Aspell, P / Atanassov, I / Avati, V / Baechler, J / Berardi, V / Berretti, M / Bossini, E / Bottigli, U / Bozzo, M / Brücken, E / Buzzo, A / Cafagna, F S / Calicchio, M / Catanesi, M G / Covault, C / Csanád, M / Csörgő, T / Deile, M /

Doubek, M / Eggert, K / Eremin, V / Ferretti, R / Ferro, F / Fiergolski, A / Garcia, F / Giani, S / Greco, V / Grzanka, L / Heino, J / Hilden, T / Intonti, R A / Kašpar, J / Kopal, J / Kundrát, V / Kurvinen, K / Lami, S / Latino, G / Lauhakangas, R / Leszko, T / Lippmaa, E / Lokajíček, M / Lo Vetere, M / Lucas Rodríguez, F / Macrí, M / Mäki, T / Mercadante, A / Minafra, N / Minutoli, S / Nemes, F / Niewiadomski, H / Oliveri, E / Oljemark, F / Orava, R / Oriunno, M / Österberg, K / Palazzi, P / Procházka, J / Quinto, M / Radermacher, E / Radicioni, E / Ravotti, F / Robutti, E / Ropelewski, L / Ruggiero, G / Saarikko, H / Santroni, A / Scribano, A / Smajek, J / Snoeys, W / Sziklai, J / Taylor, C / Turini, N / Vacek, V / Vítek, M / Welti, J / Whitmore, J / Wyszkowski, P

Physical review letters

2013 Volume 111, Issue 1, Page(s) 12001

Abstract: The TOTEM collaboration has measured the proton-proton total cross section at √s=8 TeV using a luminosity-independent method. In LHC fills with dedicated beam optics, the Roman pots have been inserted very close to the beam allowing the detection of ~90% ...

Abstract	The TOTEM collaboration has measured the proton-proton total cross section at √s=8 TeV using a luminosity-independent method. In LHC fills with dedicated beam optics, the Roman pots have been inserted very close to the beam allowing the detection of ~90% of the nuclear elastic scattering events. Simultaneously the inelastic scattering rate has been measured by the T1 and T2 telescopes. By applying the optical theorem, the total proton-proton cross section of (101.7±2.9) mb has been determined, well in agreement with the extrapolation from lower energies. This method also allows one to derive the luminosity-independent elastic and inelastic cross sections: σ(el)=(27.1±1.4) mb; σ(inel)=(74.7±1.7) mb.
Language	English
Publishing date	2013-07-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.111.012001
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Article ; Online: Double diffractive cross-section measurement in the forward region at the LHC.

Antchev, G / Aspell, P / Atanassov, I / Avati, V / Baechler, J / Berardi, V / Berretti, M / Bossini, E / Bottigli, U / Bozzo, M / Brücken, E / Buzzo, A / Cafagna, F S / Catanesi, M G / Covault, C / Csanád, M / Csörgő, T / Deile, M / Eggert, K /

Eremin, V / Ferro, F / Fiergolski, A / Garcia, F / Giani, S / Greco, V / Grzanka, L / Heino, J / Hilden, T / Karev, A / Kašpar, J / Kopal, J / Kundrát, V / Kurvinen, K / Lami, S / Latino, G / Lauhakangas, R / Leszko, T / Lippmaa, E / Lippmaa, J / Lokajíček, M / Losurdo, L / Lo Vetere, M / Lucas Rodríguez, F / Macrí, M / Mäki, T / Mercadante, A / Minafra, N / Minutoli, S / Nemes, F / Niewiadomski, H / Oliveri, E / Oljemark, F / Orava, R / Oriunno, M / Österberg, K / Palazzi, P / Procházka, J / Quinto, M / Radermacher, E / Radicioni, E / Ravotti, F / Robutti, E / Ropelewski, L / Ruggiero, G / Saarikko, H / Scribano, A / Smajek, J / Snoeys, W / Sziklai, J / Taylor, C / Turini, N / Vacek, V / Vítek, M / Welti, J / Whitmore, J / Wyszkowski, P

Physical review letters

2013 Volume 111, Issue 26, Page(s) 262001

Abstract: The first double diffractive cross-section measurement in the very forward region has been carried out by the TOTEM experiment at the LHC with a center-of-mass energy of sqrt[s]=7 TeV. By utilizing the very forward TOTEM tracking detectors T1 and T2, ... ...

Abstract	The first double diffractive cross-section measurement in the very forward region has been carried out by the TOTEM experiment at the LHC with a center-of-mass energy of sqrt[s]=7 TeV. By utilizing the very forward TOTEM tracking detectors T1 and T2, which extend up to \|η\|=6.5, a clean sample of double diffractive pp events was extracted. From these events, we determined the cross section σDD=(116±25) μb for events where both diffractive systems have 4.7<\|η\|min<6.5.
Language	English
Publishing date	2013-12-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.111.262001
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Article ; Online: High-precision measurement of the

Aaltonen, T / Amerio, S / Amidei, D / Anastassov, A / Annovi, A / Antos, J / Apollinari, G / Appel, J A / Arisawa, T / Artikov, A / Asaadi, J / Ashmanskas, W / Auerbach, B / Aurisano, A / Azfar, F / Badgett, W / Bae, T / Barbaro-Galtieri, A / Barnes, V E /

Barnett, B A / Barria, P / Bartos, P / Bauce, M / Bedeschi, F / Behari, S / Bellettini, G / Bellinger, J / Benjamin, D / Beretvas, A / Bhatti, A / Bland, K R / Blumenfeld, B / Bocci, A / Bodek, A / Bortoletto, D / Boudreau, J / Boveia, A / Brigliadori, L / Bromberg, C / Brucken, E / Budagov, J / Budd, H S / Burkett, K / Busetto, G / Bussey, P / Butti, P / Buzatu, A / Calamba, A / Camarda, S / Campanelli, M / Carls, B / Carlsmith, D / Carosi, R / Carrillo, S / Casal, B / Casarsa, M / Castro, A / Catastini, P / Cauz, D / Cavaliere, V / Cerri, A / Cerrito, L / Chen, Y C / Chertok, M / Chiarelli, G / Chlachidze, G / Cho, K / Chokheli, D / Clark, A / Clarke, C / Convery, M E / Conway, J / Corbo, M / Cordelli, M / Cox, C A / Cox, D J / Cremonesi, M / Cruz, D / Cuevas, J / Culbertson, R / d'Ascenzo, N / Datta, M / de Barbaro, P / Demortier, L / Deninno, M / D'Errico, M / Devoto, F / Di Canto, A / Di Ruzza, B / Dittmann, J R / Donati, S / D'Onofrio, M / Dorigo, M / Driutti, A / Ebina, K / Edgar, R / Elagin, A / Erbacher, R / Errede, S / Esham, B / Farrington, S / Fernández Ramos, J P / Field, R / Flanagan, G / Forrest, R / Franklin, M / Freeman, J C / Frisch, H / Funakoshi, Y / Galloni, C / Garfinkel, A F / Garosi, P / Gerberich, H / Gerchtein, E / Giagu, S / Giakoumopoulou, V / Gibson, K / Ginsburg, C M / Giokaris, N / Giromini, P / Glagolev, V / Glenzinski, D / Gold, M / Goldin, D / Golossanov, A / Gomez, G / Gomez-Ceballos, G / Goncharov, M / González López, O / Gorelov, I / Goshaw, A T / Goulianos, K / Gramellini, E / Grosso-Pilcher, C / Guimaraes da Costa, J / Hahn, S R / Han, J Y / Happacher, F / Hara, K / Hare, M / Harr, R F / Harrington-Taber, T / Hatakeyama, K / Hays, C / Heinrich, J / Herndon, M / Hocker, A / Hong, Z / Hopkins, W / Hou, S / Hughes, R E / Husemann, U / Hussein, M / Huston, J / Introzzi, G / Iori, M / Ivanov, A / James, E / Jang, D / Jayatilaka, B / Jeon, E J / Jindariani, S / Jones, M / Joo, K K / Jun, S Y / Junk, T R / Kambeitz, M / Kamon, T / Karchin, P E / Kasmi, A / Kato, Y / Ketchum, W / Keung, J / Kilminster, B / Kim, D H / Kim, H S / Kim, J E / Kim, M J / Kim, S H / Kim, S B / Kim, Y J / Kim, Y K / Kimura, N / Kirby, M / Kondo, K / Kong, D J / Konigsberg, J / Kotwal, A V / Kreps, M / Kroll, J / Kruse, M / Kuhr, T / Kurata, M / Laasanen, A T / Lammel, S / Lancaster, M / Lannon, K / Latino, G / Lee, H S / Lee, J S / Leo, S / Leone, S / Lewis, J D / Limosani, A / Lipeles, E / Lister, A / Liu, Q / Liu, T / Lockwitz, S / Loginov, A / Lucchesi, D / Lucà, A / Lueck, J / Lujan, P / Lukens, P / Lungu, G / Lys, J / Lysak, R / Madrak, R / Maestro, P / Malik, S / Manca, G / Manousakis-Katsikakis, A / Marchese, L / Margaroli, F / Marino, P / Matera, K / Mattson, M E / Mazzacane, A / Mazzanti, P / McNulty, R / Mehta, A / Mehtala, P / Menzione, A / Mesropian, C / Miao, T / Michielin, E / Mietlicki, D / Mitra, A / Miyake, H / Moed, S / Moggi, N / Moon, C S / Moore, R / Morello, M J / Mukherjee, A / Muller, Th / Murat, P / Mussini, M / Nachtman, J / Nagai, Y / Naganoma, J / Nakano, I / Napier, A / Nett, J / Nigmanov, T / Nodulman, L / Noh, S Y / Norniella, O / Oakes, L / Oh, S H / Oh, Y D / Okusawa, T / Orava, R / Ortolan, L / Pagliarone, C / Palencia, E / Palni, P / Papadimitriou, V / Parker, W / Pauletta, G / Paulini, M / Paus, C / Phillips, T J / Piacentino, G / Pianori, E / Pilot, J / Pitts, K / Plager, C / Pondrom, L / Poprocki, S / Potamianos, K / Pranko, A / Prokoshin, F / Ptohos, F / Punzi, G / Redondo Fernández, I / Renton, P / Rescigno, M / Rimondi, F / Ristori, L / Robson, A / Rodriguez, T / Rolli, S / Ronzani, M / Roser, R / Rosner, J L / Ruffini, F / Ruiz, A / Russ, J / Rusu, V / Sakumoto, W K / Sakurai, Y / Santi, L / Sato, K / Saveliev, V / Savoy-Navarro, A / Schlabach, P / Schmidt, E E / Schwarz, T / Scodellaro, L / Scuri, F / Seidel, S / Seiya, Y / Semenov, A / Sforza, F / Shalhout, S Z / Shears, T / Shepard, P F / Shimojima, M / Shochet, M / Shreyber-Tecker, I / Simonenko, A / Sliwa, K / Smith, J R / Snider, F D / Song, H / Sorin, V / St Denis, R / Stancari, M / Stentz, D / Strologas, J / Sudo, Y / Sukhanov, A / Suslov, I / Takemasa, K / Takeuchi, Y / Tang, J / Tecchio, M / Teng, P K / Thom, J / Thomson, E / Thukral, V / Toback, D / Tokar, S / Tollefson, K / Tomura, T / Torre, S / Torretta, D / Totaro, P / Trovato, M / Ukegawa, F / Uozumi, S / Vázquez, F / Velev, G / Vellidis, K / Vernieri, C / Vidal, M / Vilar, R / Vizán, J / Vogel, M / Volpi, G / Wagner, P / Wallny, R / Wang, S M / Waters, D / Wester, W C / Whiteson, D / Wicklund, A B / Wilbur, S / Williams, H H / Wilson, J S / Wilson, P / Winer, B L / Wittich, P / Wolbers, S / Wolfmeister, H / Wright, T / Wu, X / Wu, Z / Yamamoto, K / Yamato, D / Yang, T / Yang, U K / Yang, Y C / Yao, W-M / Yeh, G P / Yi, K / Yoh, J / Yorita, K / Yoshida, T / Yu, G B / Yu, I / Zanetti, A M / Zeng, Y / Zhou, C / Zucchelli, S

Science (New York, N.Y.)

2022 Volume 376, Issue 6589, Page(s) 170–176

Abstract: The mass of ... ...

Abstract	The mass of the
Language	English
Publishing date	2022-04-07
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	128410-1
ISSN	1095-9203 ; 0036-8075
ISSN (online)	1095-9203
ISSN	0036-8075
DOI	10.1126/science.abk1781
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Article ; Online: Search for the Exotic Meson X(5568) with the Collider Detector at Fermilab.

Barnett, B A / Barria, P / Bartos, P / Bauce, M / Bedeschi, F / Behari, S / Bellettini, G / Bellinger, J / Benjamin, D / Beretvas, A / Bhatti, A / Bland, K R / Blumenfeld, B / Bocci, A / Bodek, A / Bortoletto, D / Boudreau, J / Boveia, A / Brigliadori, L / Bromberg, C / Brucken, E / Budagov, J / Budd, H S / Burkett, K / Busetto, G / Bussey, P / Butti, P / Buzatu, A / Calamba, A / Camarda, S / Campanelli, M / Canelli, F / Carls, B / Carlsmith, D / Carosi, R / Carrillo, S / Casal, B / Casarsa, M / Castro, A / Catastini, P / Cauz, D / Cavaliere, V / Cerri, A / Cerrito, L / Chen, Y C / Chertok, M / Chiarelli, G / Chlachidze, G / Cho, K / Chokheli, D / Clark, A / Clarke, C / Convery, M E / Conway, J / Corbo, M / Cordelli, M / Cox, C A / Cox, D J / Cremonesi, M / Cruz, D / Cuevas, J / Culbertson, R / d'Ascenzo, N / Datta, M / de Barbaro, P / Demortier, L / Deninno, M / D'Errico, M / Devoto, F / Di Canto, A / Di Ruzza, B / Dittmann, J R / Donati, S / D'Onofrio, M / Dorigo, M / Driutti, A / Ebina, K / Edgar, R / Elagin, A / Erbacher, R / Errede, S / Esham, B / Farrington, S / Fernández Ramos, J P / Field, R / Flanagan, G / Forrest, R / Franklin, M / Freeman, J C / Frisch, H / Funakoshi, Y / Galloni, C / Garfinkel, A F / Garosi, P / Gerberich, H / Gerchtein, E / Giagu, S / Giakoumopoulou, V / Gibson, K / Ginsburg, C M / Giokaris, N / Giromini, P / Glagolev, V / Glenzinski, D / Gold, M / Goldin, D / Golossanov, A / Gomez, G / Gomez-Ceballos, G / Goncharov, M / González López, O / Gorelov, I / Goshaw, A T / Goulianos, K / Gramellini, E / Grosso-Pilcher, C / Guimaraes da Costa, J / Hahn, S R / Han, J Y / Happacher, F / Hara, K / Hare, M / Harr, R F / Harrington-Taber, T / Hatakeyama, K / Hays, C / Heinrich, J / Herndon, M / Hocker, A / Hong, Z / Hopkins, W / Hou, S / Hughes, R E / Husemann, U / Hussein, M / Huston, J / Introzzi, G / Iori, M / Ivanov, A / James, E / Jang, D / Jayatilaka, B / Jeon, E J / Jindariani, S / Jones, M / Joo, K K / Jun, S Y / Junk, T R / Kambeitz, M / Kamon, T / Karchin, P E / Kasmi, A / Kato, Y / Ketchum, W / Keung, J / Kilminster, B / Kim, D H / Kim, H S / Kim, J E / Kim, M J / Kim, S H / Kim, S B / Kim, Y J / Kim, Y K / Kimura, N / Kirby, M / Kondo, K / Kong, D J / Konigsberg, J / Kotwal, A V / Kreps, M / Kroll, J / Kruse, M / Kuhr, T / Kurata, M / Laasanen, A T / Lammel, S / Lancaster, M / Lannon, K / Latino, G / Lee, H S / Lee, J S / Leo, S / Leone, S / Lewis, J D / Limosani, A / Lipeles, E / Lister, A / Liu, Q / Liu, T / Lockwitz, S / Loginov, A / Lucchesi, D / Lucà, A / Lueck, J / Lujan, P / Lukens, P / Lungu, G / Lys, J / Lysak, R / Madrak, R / Maestro, P / Malik, S / Manca, G / Manousakis-Katsikakis, A / Marchese, L / Margaroli, F / Marino, P / Matera, K / Mattson, M E / Mazzacane, A / Mazzanti, P / McNulty, R / Mehta, A / Mehtala, P / Mesropian, C / Miao, T / Mietlicki, D / Mitra, A / Miyake, H / Moed, S / Moggi, N / Moon, C S / Moore, R / Morello, M J / Mukherjee, A / Muller, Th / Murat, P / Mussini, M / Nachtman, J / Nagai, Y / Naganoma, J / Nakano, I / Napier, A / Nett, J / Nigmanov, T / Nodulman, L / Noh, S Y / Norniella, O / Oakes, L / Oh, S H / Oh, Y D / Okusawa, T / Orava, R / Ortolan, L / Pagliarone, C / Palencia, E / Palni, P / Papadimitriou, V / Parker, W / Pauletta, G / Paulini, M / Paus, C / Phillips, T J / Piacentino, G / Pianori, E / Pilot, J / Pitts, K / Plager, C / Pondrom, L / Poprocki, S / Potamianos, K / Pranko, A / Prokoshin, F / Ptohos, F / Punzi, G / Redondo Fernández, I / Renton, P / Rescigno, M / Rimondi, F / Ristori, L / Robson, A / Rodriguez, T / Rolli, S / Ronzani, M / Roser, R / Rosner, J L / Ruffini, F / Ruiz, A / Russ, J / Rusu, V / Sakumoto, W K / Sakurai, Y / Santi, L / Sato, K / Saveliev, V / Savoy-Navarro, A / Schlabach, P / Schmidt, E E / Schwarz, T / Scodellaro, L / Scuri, F / Seidel, S / Seiya, Y / Semenov, A / Sforza, F / Shalhout, S Z / Shears, T / Shepard, P F / Shimojima, M / Shochet, M / Shreyber-Tecker, I / Simonenko, A / Sliwa, K / Smith, J R / Snider, F D / Song, H / Sorin, V / St Denis, R / Stancari, M / Stentz, D / Strologas, J / Sudo, Y / Sukhanov, A / Suslov, I / Takemasa, K / Takeuchi, Y / Tang, J / Tecchio, M / Teng, P K / Thom, J / Thomson, E / Thukral, V / Toback, D / Tokar, S / Tollefson, K / Tomura, T / Tonelli, D / Torre, S / Torretta, D / Totaro, P / Trovato, M / Ukegawa, F / Uozumi, S / Vázquez, F / Velev, G / Vellidis, C / Vernieri, C / Vidal, M / Vilar, R / Vizán, J / Vogel, M / Volpi, G / Wagner, P / Wallny, R / Wang, S M / Waters, D / Wester, W C / Whiteson, D / Wicklund, A B / Wilbur, S / Williams, H H / Wilson, J S / Wilson, P / Winer, B L / Wittich, P / Wolbers, S / Wolfmeister, H / Wright, T / Wu, X / Wu, Z / Yamamoto, K / Yamato, D / Yang, T / Yang, U K / Yang, Y C / Yao, W-M / Yeh, G P / Yi, K / Yoh, J / Yorita, K / Yoshida, T / Yu, G B / Yu, I / Zanetti, A M / Zeng, Y / Zhou, C / Zucchelli, S

Physical review letters

2018 Volume 120, Issue 20, Page(s) 202006

Abstract: A search for the exotic meson X(5568) decaying into the B_{s}^{0}π^{±} final state is performed using data corresponding to 9.6 fb^{-1} from pp[over ¯] collisions at sqrt[s]=1960 GeV recorded by the Collider Detector at Fermilab. No evidence for this ... ...

Abstract	A search for the exotic meson X(5568) decaying into the B_{s}^{0}π^{±} final state is performed using data corresponding to 9.6 fb^{-1} from pp[over ¯] collisions at sqrt[s]=1960 GeV recorded by the Collider Detector at Fermilab. No evidence for this state is found and an upper limit of 6.7% at the 95% confidence level is set on the fraction of B_{s}^{0} produced through the X(5568)→B_{s}^{0}π^{±} process.
Language	English
Publishing date	2018-05-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.120.202006
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Search for Scalar Leptoquarks Produced via τ-Lepton-Quark Scattering in pp Collisions at sqrt[s]=13 TeV.

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T / Bossini, E / Bruschini, D / Castaldi, R / Ciocci, M A / Cipriani, M / D'Amante, V / Dell'Orso, R / Donato, S / Giassi, A / Ligabue, F / Matos Figueiredo, D / Messineo, A / Musich, M / Palla, F / Rizzi, A / Rolandi, G / Roy Chowdhury, S / Sarkar, T / Scribano, A / Spagnolo, P / Tenchini, R / Tonelli, G / Turini, N / Venturi, A / Verdini, P G / Barria, P / Campana, M / Cavallari, F / Cunqueiro Mendez, L / Del Re, D / Di Marco, E / Diemoz, M / Errico, F / Longo, E / Meridiani, P / Mijuskovic, J / Organtini, G / Pandolfi, F / Paramatti, R / Quaranta, C / Rahatlou, S / Rovelli, C / Santanastasio, F / Soffi, L / Amapane, N / Arcidiacono, R / Argiro, S / Arneodo, M / Bartosik, N / Bellan, R / Bellora, A / Biino, C / Cartiglia, N / Costa, M / Covarelli, R / Demaria, N / Finco, L / Grippo, M / Kiani, B / Legger, F / Luongo, F / Mariotti, C / Maselli, S / Mecca, A / Migliore, E / Monteno, M / Mulargia, R / Obertino, M M / Ortona, G / Pacher, L / Pastrone, N / Pelliccioni, M / Ruspa, M / Siviero, F / Sola, V / Solano, A / Soldi, D / Staiano, A / Tarricone, C / Tornago, M / Trocino, D / Umoret, G / Vlasov, E / Belforte, S / Candelise, V / Casarsa, M / Cossutti, F / De Leo, K / Della Ricca, G / Dogra, S / Hong, J / Huh, C / Kim, B / Kim, D H / Kim, J / Lee, H / Lee, S W / Moon, C S / Oh, Y D / Ryu, M S / Sekmen, S / Yang, Y C / Bak, G / Gwak, P / Kim, H / Moon, D H / Asilar, E / Kim, D / Kim, T J / Merlin, J A / Park, J / Choi, S / Han, S / Hong, B / Lee, K S / Lee, S / Park, S K / Yoo, J / Goh, J / Kim, H S / Kim, Y / Almond, J / Bhyun, J H / Jun, W / Kim, J S / Ko, S / Kwon, H / Lee, J / Oh, B H / Oh, S B / Seo, H / Yang, U K / Yoon, I / Jang, W / Kang, D Y / Kang, Y / Kim, S / Ko, B / Lee, J S H / Lee, Y / Park, I C / Roh, Y / Watson, I J / Yang, S / Ha, S / Yoo, H D / Choi, M / Kim, M R / Yu, I / Beyrouthy, T / Maghrbi, Y / Dreimanis, K / Gaile, A / Pikurs, G / Potrebko, A / Seidel, M / Veckalns, V / Strautnieks, N R / Ambrozas, M / Juodagalvis, A / Rinkevicius, A / Tamulaitis, G / Bin Norjoharuddeen, N / Yusuff, I / Zolkapli, Z / Benitez, J F / Castaneda Hernandez, A / Encinas Acosta, H A / Gallegos Maríñez, L G / León Coello, M / Murillo Quijada, J A / Sehrawat, A / Valencia Palomo, L / Ayala, G / Castilla-Valdez, H / De La Cruz-Burelo, E / Heredia-De La Cruz, I / Lopez-Fernandez, R / Mondragon Herrera, C A / Sánchez Hernández, A / Oropeza Barrera, C / Ramírez García, M / Bautista, I / Pedraza, I / Salazar Ibarguen, H A / Uribe Estrada, C / Bubanja, I / Raicevic, N / Butler, P H / Ahmad, A / Asghar, M I / Awais, A / Awan, M I M / Hoorani, H R / Khan, W A / Avati, V / Grzanka, L / Malawski, M / Bialkowska, H / Bluj, M / Boimska, B / Górski, M / Kazana, M / Szleper, M / Zalewski, P / Bunkowski, K / Doroba, K / Kalinowski, A / Konecki, M / Krolikowski, J / Muhammad, A / Araujo, M / Bastos, D / Beirão Da Cruz E Silva, C / Boletti, A / Bozzo, M / Faccioli, P / Gallinaro, M / Hollar, J / Leonardo, N / Niknejad, T / Petrilli, A / Pisano, M / Seixas, J / Varela, J / Wulff, J W / Adzic, P / Milenovic, P / Dordevic, M / Milosevic, J / Rekovic, V / Aguilar-Benitez, M / Alcaraz Maestre, J / Bedoya, Cristina F / Cepeda, M / Cerrada, M / Colino, N / De La Cruz, B / Delgado Peris, A / Fernández Del Val, D / Fernández Ramos, J P / Flix, J / Fouz, M C / Gonzalez Lopez, O / Goy Lopez, S / Hernandez, J M / Josa, M I / León Holgado, J / Moran, D / Morcillo Perez, C M / Navarro Tobar, Á / Perez Dengra, C / Pérez-Calero Yzquierdo, A / Puerta Pelayo, J / Redondo, I / Redondo Ferrero, D D / Romero, L / Sánchez Navas, S / Urda Gómez, L / Vazquez Escobar, J / Willmott, C / de Trocóniz, J F / Alvarez Gonzalez, B / Cuevas, J / Fernandez Menendez, J / Folgueras, S / Gonzalez Caballero, I / González Fernández, J R / Palencia Cortezon, E / Ramón Álvarez, C / Rodríguez Bouza, V / Soto Rodríguez, A / Trapote, A / Vico Villalba, C / Vischia, P / Bhowmik, S / Blanco Fernández, S / Brochero Cifuentes, J A / Cabrillo, I J / Calderon, A / Duarte Campderros, J / 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F / Perovic, V / Pigazzini, S / Ratti, M G / Reichmann, M / Reissel, C / Reitenspiess, T / Ristic, B / Riti, F / Ruini, D / Sanz Becerra, D A / Seidita, R / Steggemann, J / Valsecchi, D / Wallny, R / Amsler, C / Bärtschi, P / Botta, C / Brzhechko, D / Canelli, M F / Cormier, K / Del Burgo, R / Heikkilä, J K / Huwiler, M / Jin, W / Jofrehei, A / Kilminster, B / Leontsinis, S / Liechti, S P / Macchiolo, A / Meiring, P / Mikuni, V M / Molinatti, U / Neutelings, I / Reimers, A / Robmann, P / Sanchez Cruz, S / Schweiger, K / Senger, M / Takahashi, Y / Tramontano, R / Adloff, C / Kuo, C M / Lin, W / Rout, P K / Tiwari, P C / Yu, S S / Ceard, L / Chao, Y / Chen, K F / Chen, P S / Chen, Z G / Hou, W-S / Hsu, T H / Kao, Y W / Khurana, R / Kole, G / Li, Y Y / Lu, R-S / Paganis, E / Psallidas, A / Su, X F / Thomas-Wilsker, J / Tsai, L S / Wu, H Y / Yazgan, E / Asawatangtrakuldee, C / Srimanobhas, N / Wachirapusitanand, V / Agyel, D / Boran, F / Demiroglu, Z S / Dolek, F / Dumanoglu, I / Eskut, E 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D / Reis, T / Salvi, G / Schuh, T / Shepherd-Themistocleous, C H / Tomalin, I R / Williams, T / Bainbridge, R / Bloch, P / Brown, C E / Buchmuller, O / Cacchio, V / Carrillo Montoya, C A / Chahal, G S / Colling, D / Dancu, J S / Dauncey, P / Davies, G / Davies, J / Della Negra, M / Fayer, S / Fedi, G / Hall, G / Hassanshahi, M H / Howard, A / Iles, G / Knight, M / Langford, J / Lyons, L / Magnan, A-M / Malik, S / Martelli, A / Mieskolainen, M / Nash, J / Pesaresi, M / Radburn-Smith, B C / Richards, A / Rose, A / Seez, C / Shukla, R / Tapper, A / Uchida, K / Uttley, G P / Vage, L H / Virdee, T / Vojinovic, M / Wardle, N / Winterbottom, D / Coldham, K / Cole, J E / Khan, A / Kyberd, P / Reid, I D / Abdullin, S / Brinkerhoff, A / Caraway, B / Dittmann, J / Hatakeyama, K / Hiltbrand, J / Kanuganti, A R / McMaster, B / Saunders, M / Sawant, S / Sutantawibul, C / Toms, M / Wilson, J / Bartek, R / Dominguez, A / Huerta Escamilla, C / Simsek, A E / Uniyal, R / Vargas Hernandez, A M / 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Physical review letters

2024 Volume 132, Issue 6, Page(s) 61801

Abstract: The first search for scalar leptoquarks produced in τ-lepton-quark collisions is presented. It is based on a set of proton-proton collision data recorded with the CMS detector at the LHC at a center-of-mass energy of 13 TeV corresponding to an integrated ...

Abstract	The first search for scalar leptoquarks produced in τ-lepton-quark collisions is presented. It is based on a set of proton-proton collision data recorded with the CMS detector at the LHC at a center-of-mass energy of 13 TeV corresponding to an integrated luminosity of 138 fb^{-1}. The reconstructed final state consists of a jet, significant missing transverse momentum, and a τ lepton reconstructed through its hadronic or leptonic decays. Limits are set on the product of the leptoquark production cross section and branching fraction and interpreted as exclusions in the plane of the leptoquark mass and the leptoquark-τ-quark coupling strength.
Language	English
Publishing date	2024-02-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.132.061801
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Search for Inelastic Dark Matter in Events with Two Displaced Muons and Missing Transverse Momentum in Proton-Proton Collisions at sqrt[s]=13 TeV.

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Physical review letters

2024 Volume 132, Issue 4, Page(s) 41802

Abstract: A search for dark matter in events with a displaced nonresonant muon pair and missing transverse momentum is presented. The analysis is performed using an integrated luminosity of 138 fb^{-1} of proton-proton (pp) collision data at a center-of-mass ... ...

Abstract	A search for dark matter in events with a displaced nonresonant muon pair and missing transverse momentum is presented. The analysis is performed using an integrated luminosity of 138 fb^{-1} of proton-proton (pp) collision data at a center-of-mass energy of 13 TeV produced by the LHC in 2016-2018. No significant excess over the predicted backgrounds is observed. Upper limits are set on the product of the inelastic dark matter production cross section σ(pp→A^{'}→χ_{1}χ_{2}) and the decay branching fraction B(χ_{2}→χ_{1}μ^{+}μ^{-}), where A^{'} is a dark photon and χ_{1} and χ_{2} are states in the dark sector with near mass degeneracy. This is the first dedicated collider search for inelastic dark matter.
Language	English
Publishing date	2024-02-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.132.041802
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Probing Small Bjorken-x Nuclear Gluonic Structure via Coherent J/ψ Photoproduction in Ultraperipheral Pb-Pb Collisions at sqrt[s_{NN}]=5.02 TeV.

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Physical review letters

2024 Volume 131, Issue 26, Page(s) 262301

Abstract: Quasireal photons exchanged in relativistic heavy ion interactions are powerful probes of the gluonic structure of nuclei. The coherent J/ψ photoproduction cross section in ultraperipheral lead-lead collisions is measured as a function of photon-nucleus ... ...

Abstract	Quasireal photons exchanged in relativistic heavy ion interactions are powerful probes of the gluonic structure of nuclei. The coherent J/ψ photoproduction cross section in ultraperipheral lead-lead collisions is measured as a function of photon-nucleus center-of-mass energies per nucleon (W_{γN}^{Pb}) over a wide range of 40<W_{γN}^{Pb}<400 GeV. Results are obtained using data at the nucleon-nucleon center-of-mass energy of 5.02 TeV collected by the CMS experiment at the CERN LHC, corresponding to an integrated luminosity of 1.52 nb^{-1}. The cross section is observed to rise rapidly at low W_{γN}^{Pb}, and plateau above W_{γN}^{Pb}≈40 GeV, up to 400 GeV, entering a new regime of small Bjorken-x (≈6×10^{-5}) gluons being probed in a heavy nucleus. The observed energy dependence is not predicted by current quantum chromodynamic models.<br />
Language	English
Publishing date	2024-01-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.131.262301
Database	MEDical Literature Analysis and Retrieval System OnLINE

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