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  1. Book: Clostridia

    Brüggemann, Holger

    molecular biology in the post-genomic era

    2009  

    Author's details ed. by Holger Brüggemann
    Language English
    Size X, 230 S. : Ill., graph. Darst.
    Publisher Caister Acad. Press
    Publishing place Norfolk
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT015500375
    ISBN 978-1-904455-38-7 ; 1-904455-38-7
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2008 A 5583 order for loan Magazin

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  2. Book ; Thesis: Molekulare Systematik und Biogeographie der Gattung Lepidium L. und verwandter Sippen (Brassicaceae)

    Brüggemann, Holger

    2000  

    Author's details von Holger Brüggemann
    Keywords Kresse ; Phylogenetik ; Sequenzanalyse ; Biogeografie
    Subject Biogeographie ; Biologische Geographie ; Biologische Geografie ; Chemische Analyse ; Sequenzierung ; Stammesgeschichtsforschung ; Phylogenese ; Lepidium
    Language German
    Size 163 S. : graph. Darst..
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Osnabrück, Univ., Diss., 2000
    HBZ-ID HT012912618
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    004/500 available for loan (reading room) Freihandmagazin (U1)

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  3. Article ; Online: Regulatory Networks Controlling Neurotoxin Synthesis in

    Popoff, Michel R / Brüggemann, Holger

    Toxins

    2022  Volume 14, Issue 6

    Abstract: Clostridium ... ...

    Abstract Clostridium botulinum
    MeSH term(s) Animals ; Botulinum Toxins/genetics ; Botulinum Toxins/metabolism ; Botulism/microbiology ; Clostridium botulinum/genetics ; Clostridium botulinum/metabolism ; Clostridium tetani/genetics ; Clostridium tetani/metabolism ; Humans ; Neurotoxins/genetics ; Neurotoxins/metabolism
    Chemical Substances Neurotoxins ; Botulinum Toxins (EC 3.4.24.69)
    Language English
    Publishing date 2022-05-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2518395-3
    ISSN 2072-6651 ; 2072-6651
    ISSN (online) 2072-6651
    ISSN 2072-6651
    DOI 10.3390/toxins14060364
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Cutibacterium avidum

    Karlsson, Johanna / Kamenska, Nina / Matuschek, Erika / Brüggemann, Holger / Söderquist, Bo

    Microorganisms

    2024  Volume 12, Issue 3

    Abstract: Cutibacterium ... ...

    Abstract Cutibacterium avidum
    Language English
    Publishing date 2024-02-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms12030432
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Treatment of acne patients with isotretinoin increases β-diversity of a putative health-associated strain of Cutibacterium acnes within the follicular microbiome of responders.

    McDowell, Andrew / Brüggemann, Holger / Layton, Alison M

    Experimental dermatology

    2023  Volume 33, Issue 1, Page(s) e14967

    MeSH term(s) Humans ; Isotretinoin/therapeutic use ; Acne Vulgaris/microbiology ; Skin/microbiology ; Propionibacterium acnes ; Microbiota
    Chemical Substances Isotretinoin (EH28UP18IF)
    Language English
    Publishing date 2023-10-27
    Publishing country Denmark
    Document type Letter
    ZDB-ID 1130936-2
    ISSN 1600-0625 ; 0906-6705
    ISSN (online) 1600-0625
    ISSN 0906-6705
    DOI 10.1111/exd.14967
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3508: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: The value of sonication on orthopaedic implants in an everyday clinical setting - an exploratory study.

    Ponraj, Diana Salomi / Falstie-Jensen, Thomas / Brüggemann, Holger / Lange, Jeppe

    BMC musculoskeletal disorders

    2023  Volume 24, Issue 1, Page(s) 691

    Abstract: Background: Sonication of removed orthopaedic implants in suspected implant-associated infections (IAI) is widely applied internationally. However, evaluation of the utility of sonication on all implants removed in everyday standard practice is scarce. ... ...

    Abstract Background: Sonication of removed orthopaedic implants in suspected implant-associated infections (IAI) is widely applied internationally. However, evaluation of the utility of sonication on all implants removed in everyday standard practice is scarce. This exploratory study was performed to evaluate the application of sonication fluid (SF) culture on removed orthopaedic implants, irrespective of the reason for removal.
    Methods: Out of 100 removed orthopaedic implants collected between August 2019 and September 2020, 77 implants with availability of concurrent tissue culture samples were included in the study. Removed implants were categorized into a confirmed or suspected IAI group and a presumed aseptic group based on pre-operative diagnosis by the responsible surgeon. Implants were sonicated and SF culture performed under both aerobic and anaerobic conditions. The significance of all bacterial isolates was evaluated based on the CFU/mL cut-offs of the EBJIS guidelines, except for C. acnes where additional investigations were performed.
    Results: The results of SF culture in the two groups were compared with their corresponding tissue cultures. Out of the 12 cases in the confirmed/suspected IAI group, SF culture was positive in 11 cases and had increased diagnostic yield in two (17%) cases compared to tissue culture. Increased diagnostic yield of SF compared to tissue culture was seen in seven (11%) of the 65 implants in the presumed aseptic group. If growth of Cutibacterium species isolates were interpreted based on EBJIS cut-off for SF culture instead of the study-specific criteria, then two isolates considered to represent infection might have been missed while three other isolates considered contaminants would have fallen under the 'infection confirmed' category in the EBJIS guidelines.
    Conclusion: Sonication with SF culture has increased diagnostic yield compared to tissue cultures in all implants irrespective of reason for removal. However, positive SF cultures with Cutibacterium species should always be interpreted with extreme care.
    MeSH term(s) Humans ; Orthopedics ; Sonication ; Surgeons ; Acne Vulgaris ; Postoperative Complications
    Language English
    Publishing date 2023-08-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041355-5
    ISSN 1471-2474 ; 1471-2474
    ISSN (online) 1471-2474
    ISSN 1471-2474
    DOI 10.1186/s12891-023-06796-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Cutibacterium acnes.

    Ahle, Charlotte M / Feidenhansl, Cecilie / Brüggemann, Holger

    Trends in microbiology

    2022  Volume 31, Issue 4, Page(s) 419–420

    MeSH term(s) Propionibacterium acnes ; Skin/microbiology
    Language English
    Publishing date 2022-10-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 1158963-2
    ISSN 1878-4380 ; 0966-842X
    ISSN (online) 1878-4380
    ISSN 0966-842X
    DOI 10.1016/j.tim.2022.10.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3738: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: Staphylococcus saccharolyticus Associated with Prosthetic Joint Infections: Clinical Features and Genomic Characteristics

    Söderquist, Bo / Afshar, Mastaneh / Poehlein, Anja / Brüggemann, Holger

    Pathogens. 2021 Mar. 26, v. 10, no. 4

    2021  

    Abstract: The anaerobic coagulase-negative staphylococcal species Staphylococcus saccharolyticus is a member of the normal skin microbiota. However, S. saccharolyticus is rarely found in clinical specimens and its pathogenic potential is unclear. The clinical data ...

    Abstract The anaerobic coagulase-negative staphylococcal species Staphylococcus saccharolyticus is a member of the normal skin microbiota. However, S. saccharolyticus is rarely found in clinical specimens and its pathogenic potential is unclear. The clinical data of prosthetic hip (n = 5) and shoulder (n = 2) joint implant-associated infections where S. saccharolyticus was detected in periprosthetic tissue specimens are described. The prosthetic hip joint infection cases presented as “aseptic” loosening and may represent chronic, insidious, low-grade prosthetic joint infections (PJIs), eventually resulting in loosening of prosthetic components. All cases were subjected to one-stage revision surgery and the long-term outcome was good. The shoulder joint infections had an acute onset. Polymicrobial growth, in all cases with Cutibacterium acnes, was found in 4/7 patients. All but one case were treated with long-term administration of beta-lactam antibiotics. Whole-genome sequencing (WGS) of the isolates was performed and potential virulence traits were identified. WGS could distinguish two phylogenetic clades (clades 1 and 2), which likely represent distinct subspecies of S. saccharolyticus. Little strain individuality was observed among strains from the same clade. Strains of clade 2 were exclusively associated with hip PJIs, whereas clade 1 strains originated from shoulder PJIs. It is possible that strains of the two clades colonize different skin habitats. In conclusion, S. saccharolyticus has the potential to cause PJIs that were previously regarded as aseptic loosening of prosthetic joint devices.
    Keywords Staphylococcus saccharolyticus ; genomics ; hips ; microorganisms ; phylogeny ; prostheses ; surgery ; virulence
    Language English
    Dates of publication 2021-0326
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens10040397
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: Complete Genome Sequences of Two Staphylococcus saccharolyticus Strains Isolated from Prosthetic Joint Infections.

    Afshar, Mastaneh / Poehlein, Anja / Söderquist, Bo / Brüggemann, Holger

    Microbiology resource announcements

    2021  Volume 10, Issue 10

    Abstract: Staphylococcus ... ...

    Abstract Staphylococcus saccharolyticus
    Language English
    Publishing date 2021-03-11
    Publishing country United States
    Document type Journal Article
    ISSN 2576-098X
    ISSN (online) 2576-098X
    DOI 10.1128/MRA.00157-21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Staphylococcus saccharolyticus

    Söderquist, Bo / Afshar, Mastaneh / Poehlein, Anja / Brüggemann, Holger

    Pathogens (Basel, Switzerland)

    2021  Volume 10, Issue 4

    Abstract: The anaerobic coagulase-negative staphylococcal ... ...

    Abstract The anaerobic coagulase-negative staphylococcal species
    Language English
    Publishing date 2021-03-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens10040397
    Database MEDical Literature Analysis and Retrieval System OnLINE

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