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  1. Article ; Online: 'Every day is hard, being outside, but you have to do it for your child': Mixed-methods formative evaluation of a peer-led parenting intervention for homeless families.

    Bradley, Caroline / Day, Crispin / Penney, Caroline / Michelson, Daniel

    Clinical child psychology and psychiatry

    2020  Volume 25, Issue 4, Page(s) 860–876

    Abstract: We conducted a mixed-methods, formative evaluation of a peer-led parenting intervention for homeless families. Participants were parents living in temporary accommodation with self-identified difficulties related to parenting an index child aged 2-11 ... ...

    Abstract We conducted a mixed-methods, formative evaluation of a peer-led parenting intervention for homeless families. Participants were parents living in temporary accommodation with self-identified difficulties related to parenting an index child aged 2-11 years. An evidence-based programme ('Empowering Parents, Empowering Communities') was adapted for delivery with the target population in London, UK. We assessed feasibility in terms of session attendance rate, intervention completion rate and potential for impact on a range of parent-reported outcomes measures. Acceptability and appropriateness were examined by a user satisfaction measure and qualitative interviews. The intervention was delivered across three group cohorts (
    MeSH term(s) Adult ; Child ; Child Behavior ; Child, Preschool ; Empowerment ; Family ; Feasibility Studies ; Female ; Homeless Persons ; Humans ; Male ; Mental Health ; Parenting ; Parents/psychology ; Peer Group ; Problem Behavior ; Program Evaluation ; Social Support
    Language English
    Publishing date 2020-06-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 1324235-0
    ISSN 1461-7021 ; 1359-1045
    ISSN (online) 1461-7021
    ISSN 1359-1045
    DOI 10.1177/1359104520926247
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: DNA extraction from recently fertilised Atlantic salmon embryos for use in microsatellite validation of triploidy.

    Howard, Callum / Taggart, John B / Bradley, Caroline R / Gutierrez, Alejandro P / Taylor, John F / Prodöhl, Paulo A / Migaud, Herve / Bekaert, Michaël

    PloS one

    2023  Volume 18, Issue 10, Page(s) e0292319

    Abstract: The current methods used for producing triploid Atlantic salmon are generally reliable but not infallible, and each batch of triploids must be validated to ensure consumer trust and licensing compliance. Microsatellites have recently been shown to offer ... ...

    Abstract The current methods used for producing triploid Atlantic salmon are generally reliable but not infallible, and each batch of triploids must be validated to ensure consumer trust and licensing compliance. Microsatellites have recently been shown to offer a cheaper and more convenient alternative to traditional flow cytometry for triploidy validation in a commercial setting. However, incubating eggs to at least the eyed stage for microsatellite validation poses challenges, such as reduced quality and performance of triploids produced from later eggs in the stripping season. To address these issues, we propose another option: extracting DNA from recently fertilised eggs for use in conjunction with microsatellite validation. To achieve this, we have developed an optimized protocol for HotSHOT extraction that can rapidly and cheaply extract DNA from Atlantic salmon eggs, which can then be used for triploidy validation through microsatellites. Our approach offers a simpler and more cost-effective way to validate triploidy, without the need for skilled dissection or expensive kits.
    MeSH term(s) Animals ; Triploidy ; Salmo salar/genetics ; Microsatellite Repeats/genetics ; Diploidy
    Language English
    Publishing date 2023-10-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0292319
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Genetic structuring across alternative life‐history tactics and small spatial scales in brown trout (Salmo trutta)

    Rodger, Jessica R / Honkanen, Hannele M / Bradley, Caroline R / Boylan, Patrick / Prodöhl, Paulo A / Adams, Colin E

    Ecology of freshwater fish. 2021 Apr., v. 30, no. 2

    2021  

    Abstract: Facultative migration occurs when, in response to prevailing conditions, individuals in a population may (or may not) undertake a migration. The brown trout (Salmo trutta) is a species that exhibits facultative migration, where some individuals within ... ...

    Abstract Facultative migration occurs when, in response to prevailing conditions, individuals in a population may (or may not) undertake a migration. The brown trout (Salmo trutta) is a species that exhibits facultative migration, where some individuals within populations may move to mainstem rivers (fluvial–adfluvial migration), lakes (lacustrine–adfluvial migration), estuaries (partial anadromy) or sea (anadromy) to feed, while others remain resident. This study attempts to separate two alternative hypotheses for the population structuring that underpins the expression of facultative migration in this species: (a) that anadromous and nonanadromous fish comprise two gene pools; (b) that individual genetic variation or individual variation in gene–environment interactions is responsible for the expression of different life‐history tactics within the same gene pool. The study design involved sampling and analyses of anadromous and nonanadromous brown trout from three independent tributary rivers known to produce (sea‐run) trout within the same catchment. Results indicate that, in all cases, population genetic divergence was linked to geographical location and not to life‐history tactics. Two genetically distinct coexisting population pairs were identified in two separate tributaries. Despite similar environmental conditions in both tributaries, the frequency of each life‐history tactic (anadromy vs. nonanadromous) within these population pairs differed significantly. The results of this study support the hypothesis that facultative migration in brown trout is likely to be driven by a quantitative threshold trait, where the threshold value varies both among populations and among individuals within populations.
    Keywords Salmo trutta ; anadromous fish ; ecology ; experimental design ; freshwater fish ; gene pool ; genes ; genetic variation ; life history ; trout ; watersheds
    Language English
    Dates of publication 2021-04
    Size p. 174-183.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note NAL-light ; JOURNAL ARTICLE
    ZDB-ID 913011-1
    ISSN 0906-6691
    ISSN 0906-6691
    DOI 10.1111/eff.12573
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: How Does Homelessness Affect Parenting Behaviour? A Systematic Critical Review and Thematic Synthesis of Qualitative Research.

    Bradley, Caroline / McGowan, John / Michelson, Daniel

    Clinical child and family psychology review

    2017  Volume 21, Issue 1, Page(s) 94–108

    Abstract: The adverse social and physical conditions of homelessness pose significant developmental risks for children, which may be compounded or buffered by the quality of parenting behaviour they are exposed to. There is currently a limited understanding of how ...

    Abstract The adverse social and physical conditions of homelessness pose significant developmental risks for children, which may be compounded or buffered by the quality of parenting behaviour they are exposed to. There is currently a limited understanding of how parents approach their care-giving role and responsibilities while adjusting to the experience of homelessness. Advancing knowledge in this area is essential for developing acceptable, appropriate and effective interventions to support highly marginalised and vulnerable homeless families. This review explored homeless parents' perceptions of how homelessness affects their parenting behaviour and identified adaptive strategies that parents may use to mitigate the potentially negative impacts of homelessness on the quality of care-giving. A systematic search of four electronic databases (ASSIA, PsycINFO, Web of Science and MEDLINE) identified 13 published qualitative studies, all originating from the USA, which explored parenting behaviour in homeless contexts. The studies were critically appraised using the CASP qualitative assessment tool. Thematic synthesis identified the following determinants of parenting behaviour; negative self-concept in the parental role, parental mental health, material resources, challenges to autonomy and self-efficacy, daily hassles, physical environment and service context, stigma, child characteristics and lack of support. These were synthesised thematically using existing models of parenting determinants and positive parenting. Findings indicate substantive impacts of homelessness on parental mental health, parenting authority, material resources, parenting environments and social support. Parents developed a number of adaptive methods to negotiate the challenges of homeless parenting such as maintaining a positive mindset, cherishing the parental role and developing practical strategies. We conclude with recommendations that service providers should tailor parenting support to resource-constrained circumstances and that further research is required in order to better understand experiences of homeless parents in other international contexts.
    MeSH term(s) Adaptation, Psychological ; Adult ; Child ; Homeless Persons/psychology ; Humans ; Parenting/psychology ; Parents/psychology ; Qualitative Research
    Language English
    Publishing date 2017-09-19
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Systematic Review
    ZDB-ID 1445774-x
    ISSN 1573-2827 ; 1096-4037
    ISSN (online) 1573-2827
    ISSN 1096-4037
    DOI 10.1007/s10567-017-0244-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Financial trade associations and multilevel regulation

    Bradley, Caroline

    Multilevel regulation and the EU : the interplay between global, European and national normative processes , p. 73-100

    2008  , Page(s) 73–100

    Author's details Caroline Bradley
    Keywords Finanzintermediation ; Finanzmarktregulierung ; Verbraucherschutz ; EU-Recht ; Rechtsdurchsetzung ; Politisches System ; EU-Staaten
    Language English
    Publisher Martinus Nijhoff Publishers
    Publishing place Leiden [u.a.]
    Document type Article
    ISBN 978-90-04-16438-3 ; 90-04-16438-3
    Database ECONomics Information System

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  6. Article ; Online: Observations: The Introduction of "Junior Editor" Posts Within Journals.

    Bradley, Caroline / McGowan, David Ross

    Journal of graduate medical education

    2016  Volume 8, Issue 1, Page(s) 110

    MeSH term(s) Editorial Policies ; Education/methods ; Fellowships and Scholarships ; Humans ; Internship and Residency ; Peer Review, Research ; Periodicals as Topic
    Language English
    Publishing date 2016-02
    Publishing country United States
    Document type Letter
    ZDB-ID 2578612-X
    ISSN 1949-8357 ; 1949-8349
    ISSN (online) 1949-8357
    ISSN 1949-8349
    DOI 10.4300/JGME-D-15-00466.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Intensive insulin therapy in critically ill patients.

    Bradley, Caroline

    Intensive & critical care nursing

    2002  Volume 18, Issue 2, Page(s) 128–129

    MeSH term(s) Critical Illness/nursing ; Critical Illness/therapy ; Humans ; Infusions, Intravenous ; Insulin/administration & dosage ; Insulin/therapeutic use ; Intensive Care Units
    Chemical Substances Insulin
    Language English
    Publishing date 2002-09-12
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1105892-4
    ISSN 0964-3397
    ISSN 0964-3397
    DOI 10.1016/s0964-3397(02)00009-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: The glitazones: a new treatment for type 2 diabetes mellitus.

    Bradley, Caroline

    Intensive & critical care nursing

    2002  Volume 18, Issue 3, Page(s) 189–191

    Abstract: The glitazones are a new class of anti-diabetic drugs that act by improving sensitivity to insulin and are indicated in the treatment of type 2 diabetes. The glitazones have effects on carbohydrate and lipid metabolism and hold the promise of being able ... ...

    Abstract The glitazones are a new class of anti-diabetic drugs that act by improving sensitivity to insulin and are indicated in the treatment of type 2 diabetes. The glitazones have effects on carbohydrate and lipid metabolism and hold the promise of being able to influence the many components of the insulin resistance syndrome seen in type 2 diabetes. It is possible that the glitazones may be able to prevent or delay the cardiovascular disease which accompanies type 2 diabetes, long-term studies are required to determine if this is the case. In addition to drug treatment patients with type 2 diabetes should be strongly encouraged to make life style changes which will improve glycaemic control such as weight reduction and increase exercise.
    MeSH term(s) Diabetes Mellitus, Type 2/drug therapy ; Dosage Forms ; Drug Monitoring ; Humans ; Hypoglycemic Agents/therapeutic use ; Pioglitazone ; Rosiglitazone ; Thiazoles/therapeutic use ; Thiazolidinediones ; United Kingdom
    Chemical Substances Dosage Forms ; Hypoglycemic Agents ; Thiazoles ; Thiazolidinediones ; Rosiglitazone (05V02F2KDG) ; 2,4-thiazolidinedione (AA68LXK93C) ; Pioglitazone (X4OV71U42S)
    Language English
    Publishing date 2002-10-31
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1105892-4
    ISSN 0964-3397
    ISSN 0964-3397
    DOI 10.1016/s0964-3397(02)00010-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Low genetic diversity and potential inbreeding in an isolated population of alder buckthorn (Frangula alnus) following a founder effect.

    Finlay, Caroline M V / Bradley, Caroline R / Preston, S Jane / Provan, Jim

    Scientific reports

    2017  Volume 7, Issue 1, Page(s) 3010

    Abstract: Alder buckthorn (Frangula alnus) is one of Ireland's rarest tree species, and in Northern Ireland the species is now restricted to a single population in Peatlands Park, Co. Armagh numbering ca. 140 mature trees. Genotyping of 95% of the trees at nine ... ...

    Abstract Alder buckthorn (Frangula alnus) is one of Ireland's rarest tree species, and in Northern Ireland the species is now restricted to a single population in Peatlands Park, Co. Armagh numbering ca. 140 mature trees. Genotyping of 95% of the trees at nine nuclear microsatellite loci revealed that levels of genetic diversity within this population were generally lower than those reported from larger populations in Spain. Analysis of six chloroplast microsatellite loci revealed no variation. The level of F
    MeSH term(s) Chloroplasts/genetics ; Founder Effect ; Genetic Variation ; Genotyping Techniques ; Inbreeding ; Microsatellite Repeats ; Northern Ireland ; Rhamnus/classification ; Rhamnus/genetics ; Rhamnus/growth & development
    Language English
    Publishing date 2017-06-07
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-017-03166-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Stigma in science: the case of earthquake prediction.

    Joffe, Helene / Rossetto, Tiziana / Bradley, Caroline / O'Connor, Cliodhna

    Disasters

    2017  

    Abstract: This paper explores how earthquake scientists conceptualise earthquake prediction, particularly given the conviction of six earthquake scientists for manslaughter (subsequently overturned) on 22 October 2012 for having given inappropriate advice to the ... ...

    Abstract This paper explores how earthquake scientists conceptualise earthquake prediction, particularly given the conviction of six earthquake scientists for manslaughter (subsequently overturned) on 22 October 2012 for having given inappropriate advice to the public prior to the L'Aquila earthquake of 6 April 2009. In the first study of its kind, semi-structured interviews were conducted with 17 earthquake scientists and the transcribed interviews were analysed thematically. The scientists primarily denigrated earthquake prediction, showing strong emotive responses and distancing themselves from earthquake 'prediction' in favour of 'forecasting'. Earthquake prediction was regarded as impossible and harmful. The stigmatisation of the subject is discussed in the light of research on boundary work and stigma in science. The evaluation reveals how mitigation becomes the more favoured endeavour, creating a normative environment that disadvantages those who continue to pursue earthquake prediction research. Recommendations are made for communication with the public on earthquake risk, with a focus on how scientists portray uncertainty.
    Language English
    Publishing date 2017-05-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 1482668-9
    ISSN 1467-7717 ; 0361-3666
    ISSN (online) 1467-7717
    ISSN 0361-3666
    DOI 10.1111/disa.12237
    Database MEDical Literature Analysis and Retrieval System OnLINE

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