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Article ; Online: Return to Sport After Ulnar Collateral Ligament Tears Treated with Platelet-Rich Plasma Injections is Influenced by Length of Rehabilitation and Leukocyte Content of Injections: A Systematic Review.

Fucaloro, Stephen P / Kang, Alex S / Bragg, Jack T / Krivicich, Laura / Salzler, Matthew J

Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association

2024

Abstract: Purpose: To analyze the current literature assessing return to sport (RTS) outcomes after platelet-rich plasma (PRP) injections for the nonoperative treatment of ulnar collateral ligament (UCL) injuries.: Methods: A systematic review of PubMed, ... ...

Abstract	Purpose: To analyze the current literature assessing return to sport (RTS) outcomes after platelet-rich plasma (PRP) injections for the nonoperative treatment of ulnar collateral ligament (UCL) injuries. Methods: A systematic review of PubMed, Embase, and Web of Science databases was conducted in June 2023 to identify studies assessing RTS after PRP injections for UCL injuries. Tear severity, leukocyte content of PRP, rehabilitation protocol, and RTS outcomes were collected. Heterogeneity was assessed through proportional random-effects models for RTS and return to preinjury level of play (RTLP) with subgroup analysis by rehabilitation length, leukocyte content of PRP, and tear severity. Results: Eight studies with 278 partial-thickness and 44 full-thickness tears were identified. The mean age of patients ranged from 17.3 to 26 years. The mean RTS time after injection ranged from 5.2 to 25.4 weeks. High heterogeneity was observed among studies, with RTS rates ranging from 46% to 100% (I Conclusions: Studies assessing RTS after PRP injections are highly heterogeneous; however, current data suggest nonoperative RTS and RTLP rates ranging from 46% to 100% and 34% to 100%, respectively. Studies with at least 12 weeks of rehabilitation and studies using leukocyte-poor PRP demonstrated low heterogeneity and greater RTS rates. Alternatively, high heterogeneity was observed among both partial- and full-thickness tears. Level of evidence: Level IV, systematic review of Level III-IV studies.
Language	English
Publishing date	2024-03-18
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	632528-2
ISSN	1526-3231 ; 0749-8063
ISSN (online)	1526-3231
ISSN	0749-8063
DOI	10.1016/j.arthro.2024.03.017
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Article: Intrasubstance Patellar Tendon Repair with the Addition of a Bio-inductive Implant.

Bragg, Jack T / Shields, Margaret V / Salzler, Matthew J

Arthroscopy techniques

2022 Volume 12, Issue 1, Page(s) e11–e15

Abstract: Intrasubstance patellar tendon ruptures are an uncommon injury that can have devastating long-term effects for patients. Operative intervention to repair the ruptured tendon is the gold standard treatment for these injuries and can be performed using a ... ...

Abstract	Intrasubstance patellar tendon ruptures are an uncommon injury that can have devastating long-term effects for patients. Operative intervention to repair the ruptured tendon is the gold standard treatment for these injuries and can be performed using a variety of techniques. Unlike the more common patellar tendon ruptures at the level of the patella, repairs of intrasubstance ruptures are often challenging because of the poor quality of the remaining tendon fibers. Tendon repair with augmentation via bio-inductive implants has gained popularity in upper extremity literature, as it has demonstrated improved tendon strength and patient outcomes. However, there remains a sparsity of reports regarding tendon augmentation in the lower extremity literature. Here, we describe repair of an intrasubstance patellar tendon rupture using a modified SpeedBridge repair and augmentation with a bio-inductive implant.
Language	English
Publishing date	2022-12-21
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2653101-X
ISSN	2212-6287
ISSN	2212-6287
DOI	10.1016/j.eats.2022.08.051
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Article ; Online: Is Patellar Instability a Contraindication to Semiextended Tibial Nailing?: A Case Report.

Ray, Gabrielle S / Leroy, Taryn E / Ryan, Scott P / Bragg, Jack T / Salzler, Matthew J

JBJS case connector

2023 Volume 13, Issue 2

Abstract: Case: We report a 40-year-old woman with undiagnosed patellofemoral instability that worsened 8 months after intramedullary nailing of a distal left tibia fracture in the semiextended position through a partial medial parapatellar approach. Patella ... ...

Abstract	Case: We report a 40-year-old woman with undiagnosed patellofemoral instability that worsened 8 months after intramedullary nailing of a distal left tibia fracture in the semiextended position through a partial medial parapatellar approach. Patella stability and asymptomatic knee function were restored after IM nail removal, medial patellofemoral ligament repair, and left tibial tubercle transposition. Conclusion: The optimal surgical approach for tibial IM nailing in patients with chronic patellar instability has not been described. Clinicians should be cognizant of the potential for worsening patellofemoral instability in these patients when using the medial parapatellar approach in the semiextended position.
MeSH term(s)	Female ; Humans ; Adult ; Tibia/surgery ; Fracture Fixation, Intramedullary ; Joint Instability/surgery ; Patellofemoral Joint/diagnostic imaging ; Patellofemoral Joint/surgery ; Bone Nails ; Tibial Fractures/complications ; Tibial Fractures/diagnostic imaging ; Tibial Fractures/surgery ; Ankle Fractures ; Contraindications
Language	English
Publishing date	2023-04-18
Publishing country	United States
Document type	Case Reports ; Journal Article
ISSN	2160-3251
ISSN (online)	2160-3251
DOI	e20.00261
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Article ; Online: Updated recommendations for diagnosis and management of the US population for hepatitis C.

Bragg, Jack

The Journal of the American Osteopathic Association

2013 Volume 113, Issue 6, Page(s) 445–446

MeSH term(s)	Adult ; Centers for Disease Control and Prevention (U.S.)/standards ; Diagnostic Techniques, Digestive System/standards ; Disease Management ; Hepatitis C/diagnosis ; Hepatitis C/epidemiology ; Hepatitis C/therapy ; Humans ; Mass Screening/standards ; Practice Guidelines as Topic/standards ; United States/epidemiology
Language	English
Publishing date	2013-06
Publishing country	United States
Document type	Letter
ZDB-ID	410350-6
ISSN	1945-1997 ; 0003-0287 ; 0098-6151
ISSN (online)	1945-1997
ISSN	0003-0287 ; 0098-6151
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Article ; Online: Osteopathic primary care of patients with inflammatory bowel disease: a review.

Bragg, Jack D

The Journal of the American Osteopathic Association

2014 Volume 114, Issue 9, Page(s) 695–701

Abstract: Ulcerative colitis and Crohn disease are relatively common inflammatory diseases of the gastrointestinal tract that have unknown causes. A combination of abnormalities in genetics, the immune system, and the microbiome of the gut may cause inflammatory ... ...

Abstract	Ulcerative colitis and Crohn disease are relatively common inflammatory diseases of the gastrointestinal tract that have unknown causes. A combination of abnormalities in genetics, the immune system, and the microbiome of the gut may cause inflammatory bowel disease (IBD). The majority of patients with IBD are in their late teens or early twenties. Most present to their primary care physician for a diagnosis. Although gastroenterologists and surgeons do most of the endoscopy and management of IBD, these patients require a great deal of health maintenance that many never receive. Osteopathic primary care physicians can play a pivotal role in the care of patients with IBD by understanding what areas of the body are affected by the disease and what screening and monitoring are needed to keep patients healthy with the highest quality of life possible.
MeSH term(s)	Anemia/diagnosis ; Anemia/etiology ; Bone Density ; Colonic Neoplasms/complications ; Colonic Neoplasms/diagnosis ; Depression/diagnosis ; Female ; Humans ; Inflammatory Bowel Diseases/complications ; Inflammatory Bowel Diseases/diagnosis ; Inflammatory Bowel Diseases/therapy ; Osteopathic Physicians ; Papillomavirus Infections/diagnosis ; Physician's Role ; Skin Neoplasms/complications ; Skin Neoplasms/diagnosis ; Smoking Cessation ; Uterine Cervical Neoplasms/diagnosis ; Uterine Cervical Neoplasms/prevention & control ; Uterine Cervical Neoplasms/virology ; Vaccination
Language	English
Publishing date	2014-09
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	410350-6
ISSN	1945-1997 ; 0003-0287 ; 0098-6151
ISSN (online)	1945-1997
ISSN	0003-0287 ; 0098-6151
DOI	10.7556/jaoa.2014.139
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Article ; Online: Heterotopic Ossification After Anterior Cruciate Ligament Reconstruction With Quadriceps Tendon Autograft: A Case Report.

Bragg, Jack T / Hayes-Lattin, Madison / Shields, Margaret V / Salzler, Matthew J

JBJS case connector

2022 Volume 12, Issue 4

Abstract: Case: A 32-year-old healthy woman tore her right anterior cruciate ligament (ACL) and underwent reconstruction with quadriceps tendon autograft. Twelve weeks postoperatively, she had anterior thigh pain limiting knee flexion and a palpable mass in the ... ...

Abstract	Case: A 32-year-old healthy woman tore her right anterior cruciate ligament (ACL) and underwent reconstruction with quadriceps tendon autograft. Twelve weeks postoperatively, she had anterior thigh pain limiting knee flexion and a palpable mass in the anterior thigh. Imaging revealed a calcified mass near the graft site, concerning for heterotopic ossification (HO). After maturation of the heterotopic bone, she underwent debridement and HO removal. Conclusion: This is a case of HO at the quadriceps tendon autograft site after ACL reconstruction. When counseling patients, clinicians should be mindful of this possible complication and its treatment.
MeSH term(s)	Female ; Humans ; Adult ; Autografts ; Anterior Cruciate Ligament Injuries/surgery ; Tendons/transplantation ; Anterior Cruciate Ligament Reconstruction/adverse effects ; Ossification, Heterotopic/surgery
Language	English
Publishing date	2022-11-23
Publishing country	United States
Document type	Case Reports ; Journal Article
ISSN	2160-3251
ISSN (online)	2160-3251
DOI	e22.00445
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Article ; Online: Subjective Outcomes After Allograft Reconstruction and Nonoperative Treatment of Anterior Cruciate Ligament Ruptures Are Similar in Patients Aged 40 Years and Older: A 2:1 Propensity Score-Matched Analysis.

Hayes-Lattin, Madison / Sylvia, Stephen M / Bragg, Jack T / Puzzitiello, Richard N / Richmond, John C / Salzler, Matthew J

Arthroscopy, sports medicine, and rehabilitation

2023 Volume 5, Issue 3, Page(s) e657–e662

Abstract: Purpose: To compare subjective outcomes and rates of subsequent operations for patients aged 40 years and older with anterior cruciate ligament (ACL) ruptures who elected nonoperative management or allograft ACL reconstruction (ACLR).: Methods: This ... ...

Abstract	Purpose: To compare subjective outcomes and rates of subsequent operations for patients aged 40 years and older with anterior cruciate ligament (ACL) ruptures who elected nonoperative management or allograft ACL reconstruction (ACLR). Methods: This was a retrospective study comparing 2-year minimum results of nonoperative treatment and primary allograft ACLR among patients aged 40 years and older presenting to a single institution between the years 2005 and 2016. Patients who elected nonoperative management were 2:1 propensity score (PS)-matched to patients who elected ACLR based on age, sex, body mass index, sports-related mechanism of injury, Outerbridge grade III or IV chondral lesions, and medial or lateral meniscus tears. Univariate analysis was performed to compare subjective outcome measures of International Knee Documentation Committee and Marx activity level scores, subsequent operations, and satisfaction rates. Results: After 2:1 PS matching, 40 ACLR and 20 nonoperative patients with mean ages of 52.2 years and 54.5 years, respectively, were included with a mean follow-up of 5.7 years (SD 2.1 years, range 2.3-10.6 years). There were no significant differences between the groups in any of the matching variables. There were no significant differences in International Knee Documentation Committee scores (81.9 ± 14.1, CI 77.4-86.5 vs 84.3 ± 12.8, CI 78.3-90.3, Conclusions: In this PS-matched analysis of patients aged 40 years and older with ACL ruptures, patients who elected nonoperative management had similar subjective outcomes compared with those who elected allograft ACLR. Patients who elected allograft ACLR did not have fewer subsequent operations than those who elected nonoperative treatment. Level of evidence: Level III, retrospective cohort study.
Language	English
Publishing date	2023-04-19
Publishing country	United States
Document type	Journal Article
ISSN	2666-061X
ISSN (online)	2666-061X
DOI	10.1016/j.asmr.2023.03.005
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Article ; Online: Predictors of Hardware Removal in Orthopaedic Trauma Patients Undergoing Syndesmotic Ankle Fixation With Screws.

Bragg, Jack T / Masood, Raisa M / Spence, Samara S / Citron, Julia E / Moon, Andrew S / Salzler, Matthew J / Ryan, Scott P

Foot & ankle orthopaedics

2023 Volume 8, Issue 3, Page(s) 24730114231198841

Abstract: Background: Indications for removal of syndesmotic screws are not fully elucidated. This study aimed to determine factors related to elective syndesmotic screw removal.: Methods: Patients who underwent fixation of ankle syndesmotic injuries were ... ...

Abstract	Background: Indications for removal of syndesmotic screws are not fully elucidated. This study aimed to determine factors related to elective syndesmotic screw removal. Methods: Patients who underwent fixation of ankle syndesmotic injuries were included. Screw removal was offered after a minimum of 12 weeks after surgery for pain, stiffness or patient desire to remove painful or broken hardware. Patient demographics, surgical data, distance of the syndesmotic screw from the joint, location of the screw at the physeal scar, and number of syndesmotic screws placed were collected for all patients. Bivariate and multivariate analyses were performed to determine the relationship between patient characteristics and screw removal and independent predictors of hardware removal. Results: Of 160 patients, 60 patients (38%) with an average age of 36.1 (range: 18-84) years underwent elective syndesmotic screw removal at a mean of 7 (range, 3-47) months after initial fixation. The most common reason for screw removal (50/60 patients) was ankle stiffness and pain (83%). Patients who underwent screw removal were more likely to be younger (36.1 years ± 13.0 vs 46.6 years ± 18.2, Conclusion: Younger and healthier patients were more likely to undergo elective removal of syndesmotic hardware. Screw distance from joint and screw placement at the physeal scar were not significantly associated with hardware removal. Level of evidence: Level III, retrospective cohort study.
Language	English
Publishing date	2023-09-16
Publishing country	United States
Document type	Journal Article
ISSN	2473-0114
ISSN (online)	2473-0114
DOI	10.1177/24730114231198841
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Article ; Online: Preoperative factors associated with failure to reach the patient acceptable symptom state after anterior cruciate ligament reconstruction in patients aged 40 and older.

Puzzitiello, Richard N / Sylvia, Stephen M / Perrone, Gabriel S / Bragg, Jack T / Richmond, John C / Salzler, Matthew J

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA

2023 Volume 31, Issue 8, Page(s) 3204–3211

Abstract: Purpose: To perform a predictive analysis to identify preoperative patient factors associated with failure to achieve a newly defined patient acceptable symptom state (PASS) for the International Knee Documentation Committee (IKDC) Score after anterior ... ...

Abstract	Purpose: To perform a predictive analysis to identify preoperative patient factors associated with failure to achieve a newly defined patient acceptable symptom state (PASS) for the International Knee Documentation Committee (IKDC) Score after anterior cruciate ligament reconstruction (ACLR) in patients aged ≥ 40 years with a minimum of 2-year follow-up. Methods: This was a secondary analysis of a retrospective review of all patients aged 40 years or older receiving a primary allograft ACLR at a single institution between the years of 2005 and 2016, with 2-year minimum follow-up. Using an updated PASS threshold of 66.7 for the International Knee Documentation Committee (IKDC) score previously established for this patient cohort, a univariate and multivariate analysis was performed to identify preoperative patient characteristics predictive of failure to achieve PASS. Results: A total of 197 patients with a mean follow-up of 6.2 ± 2.1 years (range 2.7 - 11.2) were included in the analysis (48.5 ± 5.6 years, 51.8% female, Body Mass Index (BMI) 25.9 ± 4.4). PASS was achieved by 162 patients (82.2%). Patients who failed to achieve PASS more often had lateral compartment cartilage defects (P = 0.001) and lateral meniscus tears (P = 0.004), higher BMIs (P = 0.004), and Workers' Compensation status (P = 0.043) on univariable analysis. Factors predictive of failure to achieve PASS on multivariable analysis included BMI and lateral compartment cartilage defect (OR 1.12 [1.03-1.23], P = 0.013; OR 5.1 [1.87-13.9], P = 0.001). Conclusion: Among patients ≥ 40 years who receive a primary allograft ACLR, patients who fail to achieve PASS more often had lateral compartment cartilage defects and higher BMIs. Level of evidence: Level IV.
MeSH term(s)	Humans ; Female ; Adult ; Middle Aged ; Male ; Anterior Cruciate Ligament Injuries/surgery ; Knee Joint/surgery ; Menisci, Tibial/surgery ; Retrospective Studies ; Cartilage Diseases/surgery ; Anterior Cruciate Ligament Reconstruction
Language	English
Publishing date	2023-02-22
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1159064-6
ISSN	1433-7347 ; 0942-2056
ISSN (online)	1433-7347
ISSN	0942-2056
DOI	10.1007/s00167-023-07334-x
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Article ; Online: Arthroscopic Treatment Is a Safe and Effective Alternative to Open Treatment for Acute Septic Arthritis of the Native Knee: A Systematic Review.

Puzzitiello, Richard N / Agarwalla, Avinesh / Masood, Raisa / Bragg, Jack / Hanna, John / Pagani, Nicholas R / Salzler, Matthew J

Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association

2023 Volume 40, Issue 3, Page(s) 972–980

Abstract: Purpose: To compare complication rates, reoperation rates, and subjective outcomes after arthroscopic and open irrigation and debridement for treatment of native knee septic arthritis.: Methods: Following The Preferred Reporting Items for Systematic ... ...

Abstract	Purpose: To compare complication rates, reoperation rates, and subjective outcomes after arthroscopic and open irrigation and debridement for treatment of native knee septic arthritis. Methods: Following The Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines, a systematic review of the Embase, Cochrane, and PubMed databases was performed. Comparative studies reporting clinical outcomes after arthroscopic versus open treatment for septic arthritis of the native knee in human adults were included. Excluded were case series with <10 patients, inclusion of patients <18 years old, studies on non-native joints, abstract-only publications, and studies without stratification of the involved joint. Two reviewers in duplicate independently performed search and data extraction. The quality of the included studies was assessed with the Methodological Index for Non-Randomized Studies instrument. The mean score among the included studies was 18.2 (range 16-23). Results: Eleven studies were included, comprising 2,343 knees treated arthroscopically, and 1,595 treated with arthrotomy. Studies reported no differences in erythrocyte sedimentation rate, C-reactive protein, peripheral white blood cells, or symptom chronicity between groups. Nine studies (81.8%) attempted to control for potentially confounding variables in their analyses, and 4 studies (36.4%) reported significant differences in patient characteristics. Reoperation rates ranged from 0% to 50% for arthroscopy and 6% to 71% for arthrotomy. Complication rates ranged from 0% to 39.4% arthroscopically and 0% to 49% for arthrotomy. Superior patient-reported outcomes were achieved after arthroscopy in 2 studies that analyzed subjective outcomes. Conclusions: Arthroscopic management of native knee septic arthritis is a safe and effective alternative to open treatment and is associated with comparable complication rates, reoperation rates, hospitalization lengths, readmission rates, and superior patient-reported outcomes compared with open irrigation and debridement. Level of evidence: Level IV, systematic review of Level I, III, and IV studies.
MeSH term(s)	Adolescent ; Adult ; Humans ; Arthritis, Infectious/diagnosis ; Arthroscopy/adverse effects ; Debridement/adverse effects ; Knee Joint/surgery ; Reoperation ; Retrospective Studies
Language	English
Publishing date	2023-07-11
Publishing country	United States
Document type	Systematic Review ; Journal Article ; Review
ZDB-ID	632528-2
ISSN	1526-3231 ; 0749-8063
ISSN (online)	1526-3231
ISSN	0749-8063
DOI	10.1016/j.arthro.2023.05.038
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