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  1. Article ; Online: Thoracic Imaging in Pediatric Trauma: Are CTs Necessary?

    Lynch, Peter / Samoilov, Lucy / Brahm, Gary

    Pediatric emergency care

    2023  Volume 39, Issue 2, Page(s) 98–101

    Abstract: Objectives: Imaging algorithms for assessment of thoracic trauma in pediatric patients remain controversial, attempting to balance radiation dose and its associated risk with the need for thorough assessment of patients' injuries. This study reviewed ... ...

    Abstract Objectives: Imaging algorithms for assessment of thoracic trauma in pediatric patients remain controversial, attempting to balance radiation dose and its associated risk with the need for thorough assessment of patients' injuries. This study reviewed the value of chest radiography in detecting traumatic injuries, and the impact that computed tomography (CT) had on clinical management.
    Methods: A retrospective review of pediatric trauma patients undergoing chest radiography and thoracic CT over a 2-year period at a level 1 trauma center was performed. The incidence of various traumatic injuries was documented, with measures of sensitivity and specificity on radiography. Clinical notes were reviewed to identify any changes in care based on CT findings.
    Results: Eighty-one pediatric trauma patients underwent thoracic CT over a 2-year period, with 60 patients meeting the inclusion criteria. Radiographs identified 47 traumatic injuries out of 117 seen on the subsequent CT examinations for a sensitivity of 41% and specificity of 91%. Radiographs were most sensitive in detecting osseous injuries with a sensitivity of 54%. Additional CT findings changed management in 2 of 60 cases, or 3.3% of the time.
    Conclusions: Use of thoracic CT in pediatric trauma patients identifies a significantly greater number of injuries compared with than radiography but significantly increases radiation dose while changing management in only a very small proportion of cases. Despite the relatively small sample size, the findings reflect 2 years of experience at a level 1 trauma center, and this study suggests that it may be reasonable to decrease the frequency of cross-sectional imaging.
    MeSH term(s) Child ; Humans ; Radiography ; Tomography, X-Ray Computed/methods ; Thoracic Injuries/diagnostic imaging ; Thoracic Injuries/epidemiology ; Thoracic Injuries/complications ; Sensitivity and Specificity ; Wounds, Nonpenetrating/diagnostic imaging ; Trauma Centers ; Retrospective Studies ; Radiography, Thoracic/methods
    Language English
    Publishing date 2023-01-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632588-9
    ISSN 1535-1815 ; 0749-5161
    ISSN (online) 1535-1815
    ISSN 0749-5161
    DOI 10.1097/PEC.0000000000002896
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Redefining the concept of residual renal function with kidney sodium MRI: a pilot study.

    Lemoine, Sandrine / Akbari, Alireza / Brahm, Gary / Dorie, Justin / Tamasi, Tanya / Penny, Jarrin / McIntyre, Christopher W

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    2024  

    Abstract: Rationale & objective: The concept of residual kidney function (RKF) is exclusively based upon urine volume and small solute clearance, making RKF challenging to assess in clinical practice. The aim of this study was to test the technical feasibility of ...

    Abstract Rationale & objective: The concept of residual kidney function (RKF) is exclusively based upon urine volume and small solute clearance, making RKF challenging to assess in clinical practice. The aim of this study was to test the technical feasibility of obtaining useable 23Na-MRI kidney images in hemodialysis (HD) participants.
    Study design: We conducted an exploratory prospective study to quantify the cortico-medullary sodium gradient in healthy and HD participants. Participants fasted for eight hours prior to their study visit. Urine samples were collected to measure urinary osmolarity, before MRI. Proton and sodium pictures were merged; ROIs were delineated for the medulla and cortex when feasible. In cases where cortex could not be identified, we considered the cortico to medulla gradient (CMG) to be no longer present, resulting in a medulla-to-cortex ratio of 1.
    Setting & participants: 17 healthy volunteers and 21 HD participants.
    Findings: Median (IQR) fasting medulla to cortex ratio was significantly higher 1.56 [1.5-1.61] in healthy volunteers compared to HD patients 1.22 [1.13-1.3], p < 0.0001. Medulla to cortex ratio and median urinary osmolarity were correlated (r = 0.87, p < 0.0001) in the whole population. We found a significant association between HD vintage and medulla to cortex ratio whereas we did not find any association with urine volume. Sodium signal intensity distribution within healthy kidney describes two different peaks- relating to well defined cortex and medulla; whereas HD participants displays only a single peak indicative of the markedly lower sodium concentration.
    Limitations: This study is only an exploratory study with a modest number of patients.
    Conclusions: the application of kidney sodium MRI to the study of RKF in patients receiving maintenance HD is practical and provides a previously unavailable ability to interrogate the function of remnant tubular function.
    Language English
    Publishing date 2024-04-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/gfae070
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Ultrasound-guided wire localisation: a GPS for hidden head and neck tumours? A case series.

    Laxague, Francisco / Gualtieri, Tommaso / Brahm, Gary / Yoo, John / MacNeil, S Danielle / Fung, Kevin / Mendez, Adrian / Sahovaler, Axel / Nichols, Anthony C

    Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale

    2023  Volume 43, Issue 6, Page(s) 375–381

    Abstract: Objectives: Ultrasound-guided wire (USGW) localisation for small non-palpable tumours before a revision head and neck surgery is an attractive pre-operative option to facilitate tumour identification and decrease potential complications. We describe ... ...

    Abstract Objectives: Ultrasound-guided wire (USGW) localisation for small non-palpable tumours before a revision head and neck surgery is an attractive pre-operative option to facilitate tumour identification and decrease potential complications. We describe five cases of pre-operative USGW localisation of non-palpable head and neck lesions to facilitate surgical localisation and resection.
    Methods: All patients undergoing pre-operative USGW localisation for non-palpable tumours of the head and neck region at London Health and Sciences Center, London, Ontario, Canada, were included. All the USGW localisations were performed by the same interventional radiologist, and the surgeries were performed by fellowship trained head and neck surgeons.
    Results: Five patients were included. All patients were undergoing revision surgery for recurrent or persistent disease. All successfully underwent a pre-operative USGW localisation of the non-palpable lesion before revision surgery. All lesions were localised intra-operatively with no peri-operative complications.
    Conclusions: USGW localisation is a safe and effective pre-operative technique for the identification of small non-palpable head and neck tumours.
    MeSH term(s) Humans ; Head and Neck Neoplasms/surgery ; Neck ; Preoperative Care ; Ultrasonography, Interventional
    Language English
    Publishing date 2023-07-28
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 604898-5
    ISSN 1827-675X ; 0392-100X
    ISSN (online) 1827-675X
    ISSN 0392-100X
    DOI 10.14639/0392-100X-N2280
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Reliability of the Endoscopic Ultrasound Ulcerative Colitis (EUS-UC) score for assessment of inflammation in patients with ulcerative colitis.

    Yan, Brian M / Sey, Michael S L / Belletrutti, Paul / Brahm, Gary / Guizzetti, Leonardo / Jairath, Vipul

    Endoscopy international open

    2021  Volume 9, Issue 7, Page(s) E1116–E1122

    Abstract: Background and study ... ...

    Abstract Background and study aims
    Language English
    Publishing date 2021-06-21
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2761052-4
    ISSN 2196-9736 ; 2364-3722
    ISSN (online) 2196-9736
    ISSN 2364-3722
    DOI 10.1055/a-1481-8032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Recommendations for the Management of Incidental Hepatobiliary Findings in Adults: Endorsement and Adaptation of the 2017 and 2013 ACR Incidental Findings Committee White Papers by the Canadian Association of Radiologists Incidental Findings Working Group.

    Bird, Jeffery R / Brahm, Gary L / Fung, Christopher / Sebastian, Sunit / Kirkpatrick, Iain D C

    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes

    2020  Volume 71, Issue 4, Page(s) 437–447

    Abstract: The Canadian Association of Radiologists Incidental Findings Working Group consists of both academic subspecialty and general radiologists and is tasked with adapting and expanding upon the American College of Radiology incidental findings white papers ... ...

    Abstract The Canadian Association of Radiologists Incidental Findings Working Group consists of both academic subspecialty and general radiologists and is tasked with adapting and expanding upon the American College of Radiology incidental findings white papers to more closely apply to Canadian practice patterns, particularly more comprehensively dealing with the role of ultrasound and pursuing more cost-effective approaches to the workup of incidental findings without compromising patient care. Presented here are the 2020 Canadian guidelines for the management of hepatobiliary incidental findings. Topics covered include initial assessment of hepatic steatosis and cirrhosis, the workup of incidental liver masses identified on ultrasound and computed tomography (with algorithms presented), incidental gallbladder findings (wall thickening, calcification, and polyps), and management of incidental biliary dilatation.
    MeSH term(s) Adult ; Algorithms ; Biliary Tract Diseases/diagnostic imaging ; Canada ; Diagnostic Imaging/standards ; Humans ; Incidental Findings ; Liver Diseases/diagnostic imaging ; Societies, Medical
    Language English
    Publishing date 2020-06-09
    Publishing country United States
    Document type Journal Article ; Practice Guideline
    ZDB-ID 418190-6
    ISSN 1488-2361 ; 0846-5371 ; 0008-2902
    ISSN (online) 1488-2361
    ISSN 0846-5371 ; 0008-2902
    DOI 10.1177/0846537120928349
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Recommendations for the Management of Incidental Musculoskeletal Findings on MRI and CT.

    Di Primio, Gina / Boyd, Gordon J / Fung, Christopher I / Hurrell, Casey / Brahm, Gary L / Bird, Jeffery R / Co, Steven J / Kirkpatrick, Iain D C

    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes

    2023  Volume 74, Issue 3, Page(s) 514–525

    Abstract: The Canadian Association of Radiologists (CAR) Incidental Findings Working Group consists of both academic subspeciality and general radiologists tasked with either adapting American College of Radiology (ACR) guidelines to meet the needs of Canadian ... ...

    Abstract The Canadian Association of Radiologists (CAR) Incidental Findings Working Group consists of both academic subspeciality and general radiologists tasked with either adapting American College of Radiology (ACR) guidelines to meet the needs of Canadian radiologists or authoring new guidelines where appropriate. In this case, entirely new guidelines to deal with incidental musculoskeletal findings that may be encountered on thoracoabdominal computed tomography or magnetic resonance imaging were drafted, focussing on which findings should prompt recommendations for further workup. These recommendations discuss how to deal with incidental marrow changes, focal bone lesions, abnormalities of the pubic symphysis and sacroiliac joints, fatty soft tissue masses, manifestations of renal osteodystrophy and finally discuss opportunistic osteoporosis evaluation.
    MeSH term(s) Humans ; Incidental Findings ; Canada ; Magnetic Resonance Imaging ; Tomography, X-Ray Computed ; Radiologists
    Language English
    Publishing date 2023-01-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 418190-6
    ISSN 1488-2361 ; 0846-5371 ; 0008-2902
    ISSN (online) 1488-2361
    ISSN 0846-5371 ; 0008-2902
    DOI 10.1177/08465371231152151
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Recommendations for the Management of Incidental Pancreatic Findings in Adults by the Canadian Association of Radiologists Incidental Findings Working Group.

    Fung, Christopher I / Bigam, David L / Wong, Clarence K W / Hurrell, Casey / Bird, Jeffery R / Brahm, Gary L / Kirkpatrick, Iain D C

    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes

    2021  Volume 73, Issue 2, Page(s) 312–319

    Abstract: The Canadian Association of Radiologists Incidental Findings Working Group consists of both academic subspecialty and general radiologists and is tasked with adapting and expanding upon the American College of Radiology incidental findings white papers ... ...

    Abstract The Canadian Association of Radiologists Incidental Findings Working Group consists of both academic subspecialty and general radiologists and is tasked with adapting and expanding upon the American College of Radiology incidental findings white papers to more closely apply to Canadian practice patterns, particularly more comprehensively dealing with the role of ultrasound and pursuing more cost-effective approaches to the workup of incidental findings without compromising patient care. Presented here are the 2021 Canadian guidelines for the management of pancreatic incidental findings. Topics covered include anatomic variants, fatty atrophy, pancreatic calcifications, ductal ectasia, and management of incidental pancreatic cysts.
    Language English
    Publishing date 2021-06-21
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 418190-6
    ISSN 1488-2361 ; 0846-5371 ; 0008-2902
    ISSN (online) 1488-2361
    ISSN 0846-5371 ; 0008-2902
    DOI 10.1177/08465371211021079
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Point-of-care ultrasonography for the diagnosis of testicular torsion: a practical resident curriculum.

    Stringer, Leandra / Cocco, Sarah / Jiang, Alex / Chan, Ernest Pang / Myslik, Frank / Brahm, Gary / Razvi, Hassan / Dave, Sumit / Wang, Peter Zhan Tao

    Canadian journal of surgery. Journal canadien de chirurgie

    2021  Volume 64, Issue 2, Page(s) E191–E195

    Abstract: Background: Prompt Doppler ultrasonography to aid in diagnosis is often key to managing testicular torsion, but there may be delays in access; a faster, more widely available alternative is point-of-care ultrasonography (POCUS). The purpose of this ... ...

    Abstract Background: Prompt Doppler ultrasonography to aid in diagnosis is often key to managing testicular torsion, but there may be delays in access; a faster, more widely available alternative is point-of-care ultrasonography (POCUS). The purpose of this study was to develop and evaluate a scrotal POCUS curriculum for urology and emergency medicine residents.
    Methods: Content experts in urology, emergency medicine and diagnostic imaging collaborated in a modified Delphi method to design a practical didactic curriculum for scrotal POCUS for the identification of testicular torsion. Training included 3 online video teaching modules and a 1-hour hands-on teaching session with standardized adult patients. We evaluated participants' competency in scrotal POCUS using a validated scale. We assessed participants' knowledge, comfort and confidence in performing scrotal POCUS before and after the intervention and at 3 months.
    Results: Twenty-four urology (n = 12) and emergency medicine (n = 12) residents participated in the curriculum. After hands-on practice, 23 participants (96%) were deemed competent at scrotal POCUS. Pre-post testing showed significant improvement in knowledge (mean score 63% v. 80%, p < 0.001), comfort (mean Likert score 0.6 v. 3.6, p < 0.001) and confidence (mean Likert score 1.0 v. 2.1, p < 0.001) after the intervention. These effects were maintained at the 3-month assessment.
    Conclusion: The scrotal POCUS curriculum was effective and acceptable to both urology and emergency medicine residents. The findings suggest that scrotal POCUS can be learned effectively through a short hands-on session and didactic instruction.
    MeSH term(s) Curriculum ; Emergency Medicine/education ; Humans ; Internship and Residency ; Male ; Point-of-Care Systems ; Spermatic Cord Torsion/diagnostic imaging ; Ultrasonography ; Urology/education
    Language English
    Publishing date 2021-03-19
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 410651-9
    ISSN 1488-2310 ; 0008-428X
    ISSN (online) 1488-2310
    ISSN 0008-428X
    DOI 10.1503/cjs.019119
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Reliability of the Endoscopic Ultrasound Ulcerative Colitis (EUS-UC) score for assessment of inflammation in patients with ulcerative colitis

    Yan, Brian M. / Sey, Michael S.L. / Belletrutti, Paul / Brahm, Gary / Guizzetti, Leonardo / Jairath, Vipul

    Endoscopy International Open

    2021  Volume 09, Issue 07, Page(s) E1116–E1122

    Abstract: Background and study aims : Endoscopic ultrasound (EUS) may be a useful modality for disease assessment and risk stratification in ulcerative colitis. We assessed the reliability of a newly developed EUS index of inflammation called the EUS-Ulcerative ... ...

    Abstract Background and study aims : Endoscopic ultrasound (EUS) may be a useful modality for disease assessment and risk stratification in ulcerative colitis. We assessed the reliability of a newly developed EUS index of inflammation called the EUS-Ulcerative Colitis (EUS-UC) score.
    Patients and methods : The EUS-UC score components include total wall thickness, hyperemia, and depth of inflammation (DOI). Three blinded expert endosonographers assessed EUS videos of 58 patients with UC in triplicate. Intra- and inter-rater reliability of the hyperemia and DOI component scores were estimated using intra-class correlation coefficients (ICCs). Total wall thickness reliability estimates could not be assessed in this study. The ICCs were compared to the original indices from which they were derived.
    Results : For hyperemia, the inter-class ICC was “moderate” at 0.556 (95 % CI = 0.434–0.651) and the intra class ICC was “almost perfect” at 0.884 (95 % CI = 0.835–0.920). The newly defined hyperemia score performed better than the original index from which is was derived. The DOI inter-class ICC was “fair” at 0.335 (95 % CI = 0.201–0.464), and the intra-class ICC was “substantial” at 0.732 (95 % CI = 0.642–0.802). The DOI reliability estimates were similar to the original index from which it was derived.
    Conclusions : The hyperemia component of the EUS-UC score performed significantly better than the original index from which it was derived, but the reliability of the DOI component was suboptimal. Intra-class correlation was excellent for both components. The EUS-UC score is a promising instrument for assessment of UC and further validation is required.
    Language English
    Publishing date 2021-06-21
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2761052-4
    ISSN 2196-9736 ; 2364-3722 ; 2196-9736
    ISSN (online) 2196-9736
    ISSN 2364-3722 ; 2196-9736
    DOI 10.1055/a-1481-8032
    Database Thieme publisher's database

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  10. Article: Can Split Renal Volume Assessment by Computed Tomography Replace Nuclear Split Renal Function in Living Kidney Donor Evaluations? A Systematic Review and Meta-Analysis.

    Habbous, Steven / Garcia-Ochoa, Carlos / Brahm, Gary / Nguan, Chris / Garg, Amit X

    Canadian journal of kidney health and disease

    2019  Volume 6, Page(s) 2054358119875459

    Abstract: Background: As part of their living kidney donor assessment, all living donor candidates complete a computed tomography (CT) angiogram, but some also receive a nuclear renogram for split renal function (SRF%).: Objective: We considered whether split ... ...

    Abstract Background: As part of their living kidney donor assessment, all living donor candidates complete a computed tomography (CT) angiogram, but some also receive a nuclear renogram for split renal function (SRF%).
    Objective: We considered whether split renal volume (SRV%) assessed by CT can predict SRF%.
    Design: Systematic review and meta-analysis.
    Setting: Living donor candidates undergoing evaluation as potential living kidney donors.
    Patients: Living donor candidates who received both a nuclear renogram for split function and CT for SRV as part of their living donor work-up.
    Measurements: Split renal volume from CT scans and SRF from nuclear renography.
    Methods: We performed a systematic review and meta-analysis of the literature, abstracting data and digitizing plots where possible. We searched Medline, EMBASE, and the Cochrane Library. We added data from donor candidates assessed in London, Ontario from 2013 to 2016. We used fixed and random-effects models to pool Fisher's
    Results: After pooling 19 studies (n = 1479), we obtained a pooled correlation of
    Limitations: Most studies were retrospective and measured SRV and SRF only on selected living donor candidates. Efficiency gains in removing the SRF from the evaluation will depend on the transplant program.
    Conclusion: Split renal volume has the potential to replace SRF for some candidates. However, it is uncertain whether it can do so reliably and routinely across different transplant centers. The impact on clinical decision-making needs to be assessed in well-designed prospective studies.
    Trial registration: The digitized data are registered with Mendeley Data (doi10.17632/dyn2bfgxxj.2).
    Language English
    Publishing date 2019-09-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2765462-X
    ISSN 2054-3581
    ISSN 2054-3581
    DOI 10.1177/2054358119875459
    Database MEDical Literature Analysis and Retrieval System OnLINE

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