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  1. Article ; Online: Kickstand Technique for Intraoperative Reduction of Fifth Metacarpal Neck Fractures.

    Braig, Zachary V / Kakar, Sanjeev

    The Journal of hand surgery

    2022  Volume 47, Issue 8, Page(s) 799.e1–799.e7

    Abstract: This article reports a novel intraoperative technique for the reduction of angulated metacarpal neck fractures undergoing retrograde headless intramedullary screw fixation. This technique is a useful reduction maneuver, especially for hand surgeons ... ...

    Abstract This article reports a novel intraoperative technique for the reduction of angulated metacarpal neck fractures undergoing retrograde headless intramedullary screw fixation. This technique is a useful reduction maneuver, especially for hand surgeons operating without a first assistant, because it eliminates the need to hold manual reduction during implant placement.
    MeSH term(s) Bone Screws ; Bone Wires ; Fracture Fixation, Internal/methods ; Fractures, Bone/diagnostic imaging ; Fractures, Bone/surgery ; Hand Injuries/surgery ; Humans ; Metacarpal Bones/diagnostic imaging ; Metacarpal Bones/injuries ; Metacarpal Bones/surgery
    Language English
    Publishing date 2022-05-25
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 605716-0
    ISSN 1531-6564 ; 0363-5023
    ISSN (online) 1531-6564
    ISSN 0363-5023
    DOI 10.1016/j.jhsa.2022.02.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1431: Show issues Location:
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  2. Article ; Online: Dynamic Computed Tomography of the Distal Radioulnar Joint Versus Magnetic Resonance Imaging in Detecting Foveal Tears of the Triangular Fibrocartilage Complex.

    Braig, Zachary V / Dittman, Lauren E / Amrami, Kimberly K / Kakar, Sanjeev

    Hand (New York, N.Y.)

    2024  , Page(s) 15589447241232012

    Abstract: Background: Diagnosis of foveal triangular fibrocartilage complex (TFCC) tears remains difficult. The purpose of this study was to evaluate whether dynamic computed tomography (CT) of the distal radioulnar joint (DRUJ) has a higher sensitivity in ... ...

    Abstract Background: Diagnosis of foveal triangular fibrocartilage complex (TFCC) tears remains difficult. The purpose of this study was to evaluate whether dynamic computed tomography (CT) of the distal radioulnar joint (DRUJ) has a higher sensitivity in detecting foveal tears of the TFCC when compared with magnetic resonance imaging (MRI).
    Methods: A database query identified all patients above the age of 18 years with suspected foveal TFCC injuries who underwent bilateral dynamic CT imaging of the DRUJ, static 3T MRI, and subsequent wrist arthroscopy. All patients had evidence of foveal tenderness on clinical examination. The imaging results were validated with wrist arthroscopy.
    Results: Twelve patients with a mean age of 31 years (range, 18-53 years) were identified. Eight patients were diagnosed with a complete foveal detachment of the TFCC on wrist arthroscopy. Of the 8 patients with a foveal tear on DRUJ arthroscopy, only 3 had a preoperative physical examination suggestive of DRUJ instability. Magnetic resonance imaging identified foveal injuries in 4 of these 8 patients (sensitivity, 50%), and 3 of these were identified as only partial tears. Dynamic CT identified instability of DRUJ in 6 of 8 patients (sensitivity, 75%). Seven of 8 patients had imaging findings suggestive of a foveal tear when including either MRI or CT imaging (sensitivity, 88%). Of the 4 patients with an intact foveal attachment on arthroscopy, 3 (specificity, 75%) had a stable DRUJ on CT and all 4 (specificity, 100%) had an intact foveal attachment on MRI.
    Conclusion: Sixty-two percent of patients with foveal tears on arthroscopy have a stable DRUJ on clinical examination. When combining MRI and dynamic CT imaging of the DRUJ, the sensitivity of detecting a foveal TFCC tear approaches 88% compared with a gold standard of wrist arthroscopy.
    Language English
    Publishing date 2024-02-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2277325-3
    ISSN 1558-9455 ; 1558-9447
    ISSN (online) 1558-9455
    ISSN 1558-9447
    DOI 10.1177/15589447241232012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6820: Show issues Location:
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  3. Article ; Online: Personalized medicine: From diagnostic to adaptive.

    Braig, Zachary V

    Biomedical journal

    2019  Volume 45, Issue 1, Page(s) 132–142

    Abstract: Personalized therapy has made great strides but suffers from the lack of companion diagnostics. With the dawn of extracellular vesicle (EV) based liquid biopsies fast approaching, this article proposes a novel approach to cancer treatment - adaptive ... ...

    Abstract Personalized therapy has made great strides but suffers from the lack of companion diagnostics. With the dawn of extracellular vesicle (EV) based liquid biopsies fast approaching, this article proposes a novel approach to cancer treatment - adaptive therapy. Already being implemented in the field of radiation oncology, adaptive radiation therapy utilizes cutting-edge imaging techniques as a viable means to monitor a patient's tumor throughout the entire treatment cycle by adapting the dosage and alignment to match the dynamic tumor. Through an EV liquid biopsy, medical oncologists will also soon have the means to continuously monitor a patient's tumor as it changes over time. With this information, physicians will be able to "adapt" pre-planned therapies concurrently with the fluctuating tumor environment, thus creating a more precise personalized medicine. In this article, a theory for adaptive medicine and the current state of the field with an outlook on future challenges are discussed.
    MeSH term(s) Extracellular Vesicles/pathology ; Humans ; Liquid Biopsy/methods ; Neoplasms/diagnosis ; Neoplasms/pathology ; Precision Medicine/methods
    Language English
    Publishing date 2019-07-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2698541-X
    ISSN 2320-2890 ; 2320-2890
    ISSN (online) 2320-2890
    ISSN 2320-2890
    DOI 10.1016/j.bj.2019.05.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Osteochondritis Dissecans of the Capitellum of the Elbow: Improved Outcomes in Surgically Treated Versus Nonoperatively Treated Patients at Long-Term Follow-up.

    Braig, Zachary V / Uvodich, Mason E / Till, Sara E / Reinholz, Anna K / Morrey, Mark E / Sanchez-Sotelo, Joaquin / O'Driscoll, Shawn W / Camp, Christopher L

    Arthroscopy, sports medicine, and rehabilitation

    2023  Volume 5, Issue 2, Page(s) e435–e444

    Abstract: Purpose: To (1) report the long-term outcomes associated with both operative and nonoperative management of capitellar osteochondritis dissecans (OCD), (2) identify factors associated with failure of nonoperative management, and (3) determine whether ... ...

    Abstract Purpose: To (1) report the long-term outcomes associated with both operative and nonoperative management of capitellar osteochondritis dissecans (OCD), (2) identify factors associated with failure of nonoperative management, and (3) determine whether delay in surgery affects final outcomes.
    Methods: All patients who received a diagnosis of capitellar OCD from 1995-2020 within a geographic cohort were included. Medical records, imaging studies, and operative reports were manually reviewed to record demographic data, treatment strategies, and outcomes. The cohort was divided into 3 groups: (1) nonoperative management, (2) early surgery, and (3) delayed surgery. Delayed surgery (surgery ≥6 months after symptom onset) was considered failure of nonoperative management.
    Results: Fifty elbows with a mean follow-up period of 10.5 years (median, 10.3 years; range, 1-25 years) were studied. Of these, 7 (14%) were definitively treated nonoperatively, 16 (32%) underwent delayed surgery after at least 6 months of failed nonoperative treatment, and 27 (54%) underwent early surgical intervention. When compared with nonoperative management, surgical management resulted in superior Mayo Elbow Performance Index pain scores (40.1 vs 33,
    Conclusions: Nonoperative management of capitellar OCD failed 70% of the time. Elbows that did not undergo surgery had slightly more symptoms and decreased functional outcomes compared with those treated surgically. The greatest predictors of failure of nonoperative treatment were older age and presence of a loose body; however, an initial trial of nonoperative treatment did not adversely impact the success of future surgery.
    Level of evidence: Level III, retrospective cohort study.
    Language English
    Publishing date 2023-02-25
    Publishing country United States
    Document type Journal Article
    ISSN 2666-061X
    ISSN (online) 2666-061X
    DOI 10.1016/j.asmr.2023.01.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Bedside hip aspiration results in decrease in total general anesthesia time in pediatric patients: A multicenter study.

    Braig, Zachary V / Pradhan, Pratik / Tibbo, Meagan E / Padua, Horacio / Shaughnessy, William J / Stans, Anthony A / Larson, A Noelle / Shore, Benjamin J / Milbrandt, Todd A

    Journal of children's orthopaedics

    2022  Volume 16, Issue 6, Page(s) 512–518

    Abstract: Purpose: The purpose of this study is to compare pediatric hip aspiration in the operating room under general anesthesia or via bedside aspiration under moderate sedation and delineate the anesthetic time required.: Methods: A database query ... ...

    Abstract Purpose: The purpose of this study is to compare pediatric hip aspiration in the operating room under general anesthesia or via bedside aspiration under moderate sedation and delineate the anesthetic time required.
    Methods: A database query conducted at two academic institutions identified all patients under the age of 17 who underwent hip aspiration between 2000 and 2017. At one institution, aspiration was performed in the operating room under general anesthesia. Patients were kept anesthetized until cell count was complete. At the second institution, aspiration was performed in the emergency room at bedside under sedation. The medical record was reviewed for demographic data, hip aspiration results, diagnoses, treatment, and anesthesia time.
    Results: A total of 233 patients (233 hips) with a mean age of 7.2 years were identified. Seventy-five patients underwent aspiration in the operating room, and 158 patients underwent bedside aspiration. Patients with a negative aspiration averaged 87 min under anesthesia when performed in the operating room and 29 min under sedation when performed at bedside. Patients with a negative aspiration performed in the operating room after 5 pm averaged 99 min under anesthesia, and 73 min under anesthesia when performed between 7 am and 5 pm (p < 0.01). Seventy-eight (49%) patients who underwent bedside aspiration did not require operative intervention and therefore avoided general anesthesia.
    Conclusion: Pediatric hip aspiration performed in the operating room results in prolonged anesthesia times while synovial fluid is transported and processed. Anesthesia times are significantly longer after 5 pm. Bedside aspiration resulted in significantly less anesthesia exposure, with half of patients undergoing bedside aspiration avoiding general anesthesia altogether.
    Level of evidence: Level III.
    Language English
    Publishing date 2022-11-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2279410-4
    ISSN 1863-2548 ; 1863-2521
    ISSN (online) 1863-2548
    ISSN 1863-2521
    DOI 10.1177/18632521221135191
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6613: Show issues Location:
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  6. Article: Incidence and Epidemiology of Symptomatic Capitellar Osteochondritis Dissecans of the Elbow: A United States Population-Based Study Over a 25-Year Period.

    Uvodich, Mason E / Braig, Zachary V / Reinholz, Anna K / Till, Sara E / O'Driscoll, Shawn W / Morrey, Mark E / Sanchez-Sotelo, Joaquin / Camp, Christopher L

    Orthopaedic journal of sports medicine

    2022  Volume 10, Issue 11, Page(s) 23259671221135933

    Abstract: Background: There are limited data on the incidence of capitellar osteochondritis dissecans (OCD) in the United States (US) population.: Purpose: To determine the incidence of symptomatic capitellar OCD in a representative US subpopulation and ... ...

    Abstract Background: There are limited data on the incidence of capitellar osteochondritis dissecans (OCD) in the United States (US) population.
    Purpose: To determine the incidence of symptomatic capitellar OCD in a representative US subpopulation and identify changes in its incidence over time and to investigate the relationship between the incidence of capitellar OCD and patient sex and age.
    Study design: Descriptive epidemiology study.
    Methods: A retrospective review was performed of patients aged ≤24 years from Olmsted County, Minnesota, with symptomatic capitellar OCD over a 25-year period (1995-2019). Patients with acute osteochondral injuries, Panner disease, and hereditary arthropathy were excluded. Poisson regression was utilized to identify the predictors of a capitellar OCD diagnosis. Incidence rates (per 100,000) were assessed for changes over time. Age groups of younger (10-15 years) versus older (16-24 years) patients were compared.
    Results: A total of 45 patients (78% male) were identified. The mean age was 14.5 years (range, 10-24 years); 31 patients were in the younger group, and 14 patients were in the older group. Sport participation was seen in 89%of patients; 90% were overhead athletes, and 58% were throwing athletes. The incidence of capitellar OCD was 6.0 per 100,000 overall, 9.5 per 100,000 for male patients, and 2.6 per 100,000 for female patients. The incidence was highest for male patients in the younger group (15.3/100,000) and lowest for female patients in the older group (0.8/100,000). The estimated incidence rate ratio for younger versus older patients was 3.3 (
    Conclusion: In this US subpopulation, the overall incidence of symptomatic capitellar OCD between the ages of 10 and 24 years was 6.0 per 100,000 over the 25-year period studied, which is higher than previously reported US estimates. Incidence rates and treatment strategies did not change significantly over time.
    Language English
    Publishing date 2022-11-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2706251-X
    ISSN 2325-9671
    ISSN 2325-9671
    DOI 10.1177/23259671221135933
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Humeral stress shielding following cemented endoprosthetic reconstruction: An under-reported complication?

    Braig, Zachary V / Tagliero, Adam J / Rose, Peter S / Elhassan, Bassem T / Barlow, Jonathan D / Wagner, Eric R / Sanchez-Sotelo, Joaquin / Houdek, Matthew T

    Journal of surgical oncology

    2020  Volume 123, Issue 2, Page(s) 505–509

    Abstract: Introduction: The proximal humerus is a common location for primary and non-primary tumors. Reconstruction of the proximal humerus is commonly performed with an endoprosthesis with low rates of structural failure. The incidence and risk factors for ... ...

    Abstract Introduction: The proximal humerus is a common location for primary and non-primary tumors. Reconstruction of the proximal humerus is commonly performed with an endoprosthesis with low rates of structural failure. The incidence and risk factors for stress shielding are under reported.
    Methods: Thirty-nine (19 male, 20 female) patients underwent resection of the proximal humerus and reconstruction with a cemented modular endoprosthesis between 2000 and 2018. The mean resection length was 12 ± 4 cm and was most commonly performed for metastatic disease (n = 26, 67%).
    Results: Stress shielding was observed in 9 (23%) patients at a mean of 29 (6-132) months postoperatively. Patients with stress shielding were noted to have shorter intramedullary stem length (87 vs. 107 mm, p < .001), longer extramedullary implant length (16 vs. 14 cm, p = .01) and a higher extramedullary implant to stem length ratio (2.1 vs. 1.1, p < .001). The incidence of stress shielding was higher (p = .003) in patients reconstructed with 75 mm stem (n = 6, 67%) lengths.
    Conclusion: Stress shielding of the humerus was associated with the use of shorter stems and long extramedullary implants. The long-term ramifications of stress shielding on implant stability, complications at the time of revision surgery, and overall patient outcomes remain unknown.
    MeSH term(s) Bone Neoplasms/pathology ; Bone Neoplasms/surgery ; Female ; Follow-Up Studies ; Humans ; Humerus/physiopathology ; Humerus/surgery ; Male ; Middle Aged ; Postoperative Complications ; Prostheses and Implants/adverse effects ; Prosthesis Failure ; Reconstructive Surgical Procedures/adverse effects ; Recovery of Function ; Retrospective Studies ; Shoulder Joint/pathology ; Shoulder Joint/surgery
    Language English
    Publishing date 2020-12-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 82063-5
    ISSN 1096-9098 ; 0022-4790
    ISSN (online) 1096-9098
    ISSN 0022-4790
    DOI 10.1002/jso.26300
    Database MEDical Literature Analysis and Retrieval System OnLINE

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