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  1. Article ; Online: Vergleich der katheterassoziierten Lebensqualität bei externen Harnableitungen: Nephrostomie vs. suprapubischer Katheter.

    Wiedemann, A / Weinhofer, M / Stein, J / Linné, C / Kirschner-Hermanns, R / Schorn, A / Wagner, A / Moll, V / Unger, U / Salem, J / Liebald, T / Bannowsky, A / Wirz, S / Brammen, E / Heppner, H-J

    Der Urologe. Ausg. A

    2022  Volume 61, Issue 1, Page(s) 31–40

    Abstract: Introduction: A percutaneous nephrostomy (PCN) affects the integrity of the patient due to the requirement of an external drainage bag and regular changes. The catheter-associated quality of life (QOL) was evaluated using a validated assessment and ... ...

    Title translation Comparison of catheter-associated quality of life in external urinary diversion: nephrostomy vs. suprapubic catheter.
    Abstract Introduction: A percutaneous nephrostomy (PCN) affects the integrity of the patient due to the requirement of an external drainage bag and regular changes. The catheter-associated quality of life (QOL) was evaluated using a validated assessment and compared to similar patients with suprapubic bladder drainage.
    Methods: A validated assessment analyzing catheter-related QOL for 5 domains and 25 individual items (first published by Mary Wilde) was completed during a catheter change appointment by patients who had their unilateral or bilateral PCN for a minimum of 3 months in life-long indication.
    Results: In 66 patients (unilateral PCN: 42 patients), a moderate impairment of their catheter-related QOL was shown. The overall QOL score was median 4.0 on a scale of 0-5. This was rated lower-indicating a stronger impairment of QOL-than in patients with a suprapubic bladder catheter, who had a median score of 4.3. Significant differences were found related to the catheter type in the items "feeling of humiliation due to the PCN", "conflicts with the medical or nursing staff", "fear of painful catheter changes", "feeling ill", "being handicapped in activities of daily living" and "concern of not being able to do what one wants to do" and "fear of catheter leakages". The indication for the PCN due to a malignant or benign underlying disease was not associated with the catheter-related QOL.
    Conclusion: For the first time, the catheter-related QOL was found to be moderately impaired in patients with a PCN using a validated assessment. Affected individuals report feeling "ill" and "limited/disabled" in activities of daily living; thus, the surgical indication should be strict. Fear of painful catheter changes and of catheter leakages indicates the need of technically correct catheter changes.
    MeSH term(s) Activities of Daily Living ; Catheters ; Humans ; Nephrostomy, Percutaneous ; Prospective Studies ; Quality of Life ; Urinary Diversion
    Language German
    Publishing date 2022-01-13
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 204041-4
    ISSN 1433-0563 ; 0340-2592 ; 0375-4685
    ISSN (online) 1433-0563
    ISSN 0340-2592 ; 0375-4685
    DOI 10.1007/s00120-021-01745-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Teaching distinguishing semiological features improves diagnostic accuracy of seizure-like events by emergency physicians.

    Grönheit, Wenke / Behrens, Vanessa / Liakina, Tatjana / Kellinghaus, Christoph / Noachtar, Soheyl / Popkirov, Stoyan / Wehner, Tim / Brammen, Eva / Wellmer, Jörg

    Neurological research and practice

    2022  Volume 4, Issue 1, Page(s) 56

    Abstract: Background: Misdiagnosis of seizure-like events (SLE) in emergency situations is common. Here, we evaluate whether a single, video-based lesson highlighting distinguishing semiological features can improve the diagnostic accuracy of emergency physicians ...

    Abstract Background: Misdiagnosis of seizure-like events (SLE) in emergency situations is common. Here, we evaluate whether a single, video-based lesson highlighting distinguishing semiological features can improve the diagnostic accuracy of emergency physicians for epileptic seizures (ES), psychogenic non-epileptic seizures (PNES) and syncopes (SY).
    Methods: 40 emergency physicians (24 anesthetists, nine surgeons and seven internal medicine specialists by primary specialty) participated in a prospective trial on the diagnostic accuracy of SLE. They assessed video-displayed SLE at two time points: before and after a lecture on distinguishing semiological features. In the lecture, semiological features were demonstrated using patient videos, some were acted by the instructor in addition. The increase in correct diagnoses and recognition of distinguishing semiological features were analyzed.
    Results: Before the lesson, 45% of 200 SLE-ratings were correct: 15% of SY (n = 40), 30% of PNES (n = 40), 59% of ES (n = 120, focal to bilateral tonic-clonic seizures (FBTCS) 87.5% (n = 40), focal impaired aware seizures (FIAS) 45% (n = 80)). Semiology teaching increased both the rate of correct diagnoses of SLE to overall 79% (p < 0.001) (ES 91% (p < 0.001), FBCTS 98% (n.s.), FIAS 88% (p < 0.001), PNES 88% (p < 0.001), SY 35% (p < 0.001)), and the number of recognized distinguishing semiological features. We identified several semiological features with high entity specific positive predictive values (> 0.8).
    Conclusions: A single 45-min video-based lesson highlighting distinguishing semiological features improves the diagnostic accuracy of ES, PNES and SY by emergency physicians. We expect that including this aspect into the curriculum of emergency physicians will lead to better individual patient treatment in pre-hospital medicine and more appropriate subsequent use of clinical resources.
    Language English
    Publishing date 2022-11-14
    Publishing country England
    Document type Journal Article
    ISSN 2524-3489
    ISSN (online) 2524-3489
    DOI 10.1186/s42466-022-00220-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Hat eine Ventilversorgung Vorteile bei der katheterassoziierten Lebensqualität? : Ergebnisse einer Untersuchung an 427 Katheterträgern in lebenslanger Indikation.

    Wiedemann, Andreas / Mourad, A / Gedding, C / Stein, J / Manseck, A / Kirschner-Hermanns, R / Liebald, T / Linné, C / Schorn, A / Wagner, A / Moll, V / Unger, U / Eisenhardt, A / Salem, J / Bannowsky, A / Wirz, S / Brammen, E / Heppner, H-J

    Urologie (Heidelberg, Germany)

    2022  Volume 61, Issue 9, Page(s) 959–970

    Abstract: Background: In urology, a subset of patients with lifelong urine drainage are fitted with a catheter valve. Data on catheter-related quality of life (crqol) in this subset of patients are missing.: Aim: Clarification of the whether there are ... ...

    Title translation Are there benefits for catheter valves for catheter-associated quality of life? : Results of an investigation in 427 catheter wearers with life-long indication.
    Abstract Background: In urology, a subset of patients with lifelong urine drainage are fitted with a catheter valve. Data on catheter-related quality of life (crqol) in this subset of patients are missing.
    Aim: Clarification of the whether there are advantages for valve-aided catheters in comparison with continuous urine drainage in catheter wearers with a lifelong indication.
    Methods: In all, 357 patients with a catheter with lifelong indication of continuous urine drainage from a previous study were compared with 70 valve-aided patients. The crqol was evaluated by a validated assessment with 25 items and five domains.
    Results: There were statistically more patients with a suprapubic catheter than with a transurethral indwelling catheter (73.4 vs. 54.4%, p = 0.005), significantly more patients with bladder voiding dysfunction (73.5 vs. 52.6%, p = 0.003) and significantly more patients with small catheter sizes (p = 0.001). Crqol was altogether slightly impaired with a median score of 4.2 (no impairment indicated by 5 points) in valve-aided patients, but crqol was more impaired in valve-aided patients compared to patients with continuous drainage (4.4 points, n. s.). Some items demonstrated more problems dealing with urinary urge in valve-aided patients, but catheter-related pain was more often worse in patients with continuous drainage.
    Conclusion: There is no clear evidence for an advantage of a catheter valve over a continuous urine drainage system. Thus, the decision regarding a catheter-valve system must be made individually according to the indication and the preferences of the patient.
    MeSH term(s) Catheters, Indwelling/adverse effects ; Drainage/methods ; Humans ; Quality of Life ; Urinary Bladder ; Urinary Catheterization/adverse effects
    Language German
    Publishing date 2022-03-22
    Publishing country Germany
    Document type Journal Article
    ISSN 2731-7072
    ISSN (online) 2731-7072
    DOI 10.1007/s00120-022-01807-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Lebensqualität bei Trägern eines suprapubischen oder transurethralen Harnblasenkatheters als lebenslange Dauerversorgung.

    Wiedemann, A / Gedding, C / Heese, M / Stein, J / Manseck, A / Kirschner-Hermanns, R / Karstedt, H / Schorn, A / Wagner, A / Moll, V / Unger, U / Eisenhardt, A / Bannowsky, A / Linné, C / Wirz, S / Brammen, E / Heppner, H-J

    Der Urologe. Ausg. A

    2021  Volume 61, Issue 1, Page(s) 18–30

    Abstract: Background: The insertion of a Foley catheter (FC) or a suprapubic catheter (SPC) in lifelong intent is an intervention with significant complications, comorbidities and impact on the further life that has not yet been analyzed.: Methodology: The ... ...

    Title translation Quality of life for wearers of a suprapubic or transurethral bladder catheter as lifelong permanent care.
    Abstract Background: The insertion of a Foley catheter (FC) or a suprapubic catheter (SPC) in lifelong intent is an intervention with significant complications, comorbidities and impact on the further life that has not yet been analyzed.
    Methodology: The analysis was based on a validated assessment of catheter-related QoL with 25 items in 5 domains and applied to patients with a Foley or suprapubic catheter in lifelong indication and with the catheter in place for at least 3 months. Assessment data were enriched with information on the type and diameter of the catheter as well as demographic data.
    Results: Questionnaires from 357 patients (260 male, 97 female, 193 with suprapubic catheter, 162 with Foley catheter, 2 no information) were included in the study. Patients with a Foley catheter were significantly older than patients with a suprapubic catheter (78.9 ± 11.1 years vs. 74.4. ± 12.6 years, p < 0.001). The average QoL score was 4.1 points on a scale from 1 (maximum impairment of QoL) to 5 (no impairment of QoL) indicating a moderately negative impact on QoL. Scores below the average were mainly driven and accompanied by a fear of urine leakage, urine odor, painful catheter changes and urinary infections increasing with age. Additionally, patients were worried about negative effects on their daily life activities due to the catheter. These worries seemed to be more pronounced in females with urinary incontinence, patients with a catheter size ≥ 18 Ch. and with an age of < 70 years. The type of catheter showed a greater impact on the QoL in females with suprapubic catheters when compared with males in contrast to patients with transurethral catheters.
    Conclusion: The results of the study provide further information for the medical clarification for patients and caregivers, having to decide between a lifelong catheter drainage or alternatives, such as provision of an aid or surgical recanalization.
    MeSH term(s) Aged ; Female ; Humans ; Male ; Quality of Life ; Urinary Bladder ; Urinary Catheterization ; Urinary Catheters ; Urinary Tract Infections
    Language German
    Publishing date 2021-10-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 204041-4
    ISSN 1433-0563 ; 0340-2592 ; 0375-4685
    ISSN (online) 1433-0563
    ISSN 0340-2592 ; 0375-4685
    DOI 10.1007/s00120-021-01642-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Effect of blood pressure and total cholesterol measurement on risk prediction using the Systematic COronary Risk Evaluation (SCORE).

    Ulbricht, Sabina / Gross, Stefan / Brammen, Eva / Weymar, Franziska / John, Ulrich / Meyer, Christian / Dörr, Marcus

    BMC cardiovascular disorders

    2018  Volume 18, Issue 1, Page(s) 84

    Abstract: Background: To compare the reproducibility in total cholesterol (TC), systolic blood pressure (BP), and the resulting Systematic COronary Risk Evaluation (SCORE) obtained by an in-office cardio-preventive screening program (SP) and a subsequent program ... ...

    Abstract Background: To compare the reproducibility in total cholesterol (TC), systolic blood pressure (BP), and the resulting Systematic COronary Risk Evaluation (SCORE) obtained by an in-office cardio-preventive screening program (SP) and a subsequent program performed in a clinical trial examination center (EP).
    Methods: A total of 307 individuals (60.3% female, mean age = 52.8 years) participated. According to TC and BP measurements at the SP and EP, three variables were created: the SCORE
    Results: TC and BP values from the SP were significantly higher than those from the EP. Among individuals with a decreased SCORE value at the EP (compared to the SP), younger age was associated with a higher improvement in risk estimation compared with older age. Female sex was associated with higher risk improvement in the SCORE between the SP and the EP compared with male sex. Associations between both demographics and M1 (M2) achieved statistical significance at the 75.0th (50th) percentile.
    Conclusions: The reproducibility of results in cardiovascular risk prediction seems to be influenced by the accuracy of BP measurement. It seems that younger individuals and females are more likely to benefit from accuracy compared with older individuals and males.
    MeSH term(s) Adult ; Age Factors ; Aged ; Biomarkers/blood ; Blood Pressure ; Blood Pressure Determination ; Cholesterol/blood ; Coronary Disease/blood ; Coronary Disease/diagnosis ; Coronary Disease/etiology ; Coronary Disease/physiopathology ; Decision Support Techniques ; Dyslipidemias/blood ; Dyslipidemias/complications ; Dyslipidemias/diagnosis ; Female ; Health Status ; Humans ; Hypertension/complications ; Hypertension/diagnosis ; Hypertension/physiopathology ; Male ; Middle Aged ; Office Visits ; Predictive Value of Tests ; Prognosis ; Reproducibility of Results ; Risk Assessment ; Risk Factors ; Sex Factors
    Chemical Substances Biomarkers ; Cholesterol (97C5T2UQ7J)
    Language English
    Publishing date 2018-05-04
    Publishing country England
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2059859-2
    ISSN 1471-2261 ; 1471-2261
    ISSN (online) 1471-2261
    ISSN 1471-2261
    DOI 10.1186/s12872-018-0823-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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