LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 23

Search options

  1. Article ; Online: Promoting surgical research in the Global South: Perspectives from surgical trainee researchers.

    Naganathan, Gayathri / Sue-Chue-Lam, Colin / Brar, Amanpreet / Azzie, Georges

    Surgery

    2022  Volume 171, Issue 4, Page(s) 1131–1132

    MeSH term(s) Biomedical Research ; Humans ; Research Personnel
    Language English
    Publishing date 2022-01-26
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 202467-6
    ISSN 1532-7361 ; 0039-6060
    ISSN (online) 1532-7361
    ISSN 0039-6060
    DOI 10.1016/j.surg.2021.09.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Bridging the Knowledge Gap: A Toolkit on Reproductive Rights for Pediatric Surgeons in the Post-Dobbs Era.

    Mannava, Sindhu V / Brar, Amanpreet / Patwardhan, Utsav / Godfrey, Jodi / Berdan, Elizabeth / Gow, Kenneth / Knod, J Leslie

    Journal of pediatric surgery

    2024  

    Abstract: Background: The ripple effect of the Supreme Court ruling in Dobbs v. Jackson Women's Health Organization has impacted physicians and patients across numerous medical specialties. In pediatric surgery, the patient population ranges from fetus to the ... ...

    Abstract Background: The ripple effect of the Supreme Court ruling in Dobbs v. Jackson Women's Health Organization has impacted physicians and patients across numerous medical specialties. In pediatric surgery, the patient population ranges from fetus to the pregnant patient. There is a gap in the knowledge of pediatric surgeons regarding abortion laws and access. This project aims to bridge the gap by creating access to reliable resources which may be used to optimize patient care and support physicians.
    Methods: We collaborated with the Reproductive Health Coalition, co-founded by the American Medical Women's Association and Doctors for America, to curate a list of resources beneficial to pediatric surgeons.
    Results: We created a web-based toolkit with the purpose of providing easily accessible and reliable information on reproductive rights in the United States. We identified up-to-date resources on state-by-state abortion laws, legal resources, patient-centered information on obtaining abortion care, and resources for physicians interested in getting involved in advocacy.
    Conclusion: Pediatric surgery rests at a critical juncture with respect to reproductive rights in the United States. Our toolkit enables users to understand the current climate and identify next steps to advocate for patients and physicians amidst a formidable legal environment.
    Level of evidence: Level V.
    Language English
    Publishing date 2024-03-16
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80165-3
    ISSN 1531-5037 ; 0022-3468
    ISSN (online) 1531-5037
    ISSN 0022-3468
    DOI 10.1016/j.jpedsurg.2024.03.029
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Reviewing the Reviewers Potential Financial Conflicts of Interest in Editorial Boards of Surgery Journals.

    Elsolh, Basheer / Brar, Amanpreet / Gyawali, Bishal / Patel, Sunil V

    Annals of surgery

    2021  Volume 276, Issue 6, Page(s) e1089–e1094

    Abstract: Objective: To assess the prevalence, magnitude, and disclosure status of industry funding in editorial boards of surgery journals.: Summary of background data: Financial COI can bias research. Although authors seeking to publish in peer-reviewed ... ...

    Abstract Objective: To assess the prevalence, magnitude, and disclosure status of industry funding in editorial boards of surgery journals.
    Summary of background data: Financial COI can bias research. Although authors seeking to publish in peer-reviewed surgery journals are required to provide COI disclosures, editorial board members' COI disclosures are generally not disclosed to readers.
    Methods: We present a cross-sectional analysis of industry funding to editorial board members of high-impact surgery journals. We reviewed top US-based surgery journals by impact factor to determine the presence of financial COI in members of each journal's editorial board. The prevalence and magnitude of COI was determined using 2018 industry reported payments found in the Centers for Medicare and Medicaid Services Open Payments database. Journal websites were also reviewed looking for the presence of editorial board disclosure statements.
    Results: A total of 1002 names of editorial board members from the top 10 high-impact American surgery journals were identified. Of 688 individual physicians based in the USA, 452 (65.7%) were found to have received industry payments in 2018, totaling $21,916,503 with a median funding amount per physician of $1253 (interquartile range $156-$10,769). Funding levels varied by surgical specialty and journal. Editorial board disclosure information was found in only 3.3% of physicians.
    Conclusions: Industry funding to editorial board members of high impact surgery journals is prevalent and underreported. Mechanisms of disclosure for COI are needed at the editorial board level to provide readers full transparency. This would acknowledge this COI of editorial board members, and thereby attempt to potentially further reduce the risk of bias in editorial decisions.
    MeSH term(s) Aged ; United States ; Humans ; Conflict of Interest ; Cross-Sectional Studies ; Medicare ; Periodicals as Topic ; Disclosure
    Language English
    Publishing date 2021-06-02
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 340-2
    ISSN 1528-1140 ; 0003-4932
    ISSN (online) 1528-1140
    ISSN 0003-4932
    DOI 10.1097/SLA.0000000000004929
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Racial, ethnic and socioeconomic disparities in diagnosis, treatment, and survival of patients with breast cancer.

    Azin, Arash / Tahmasebi, Houman / Brar, Amanpreet / Azin, Sam / Ko, Gary / Covelli, Andrea / Cil, Tulin

    American journal of surgery

    2022  

    Abstract: Background: The objective of this study was to determine the influence of race/ethnicity and socioeconomic status (SES) on breast cancer outcomes.: Methods: A retrospective analysis was performed of Non-Hispanic Black (NHB), Non-Hispanic White (NHW), ...

    Abstract Background: The objective of this study was to determine the influence of race/ethnicity and socioeconomic status (SES) on breast cancer outcomes.
    Methods: A retrospective analysis was performed of Non-Hispanic Black (NHB), Non-Hispanic White (NHW), and Hispanic patients with non-metastatic breast cancer in the SEER cancer registry between 2007 and 2016.
    Results: A total of 382,975 patients were identified. On multivariate analysis, NHB (OR 1.18, 95%CI: 1.15-1.20) and Hispanic (OR 1.20, 95%CI: 1.17-1.22) patients were more likely to present with higher stage disease than NHW patients. There was an increased likelihood of not undergoing breast-reconstruction for NHB (OR 1.07, 95%CI: 1.03-1.11) and Hispanic patients (OR 1.60, 95%CI 1.54-1.66). NHB patients had increased hazard for all-cause mortality (HR: 1.13, 95%CI 1.10-1.16). All-cause mortality increased across SES categories (lower SES: HR 1.33, 95%CI 1.30-1.37, middle SES: HR 1.20, 95%CI 1.17-1.23).
    Conclusions: This population-based analysis confirms worse disease presentation, access to surgical therapy, and survival across racial, ethnic, and socioeconomic factors. These disparities were compounded across worsening SES and insurance coverage.
    Language English
    Publishing date 2022-08-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2953-1
    ISSN 1879-1883 ; 0002-9610
    ISSN (online) 1879-1883
    ISSN 0002-9610
    DOI 10.1016/j.amjsurg.2022.07.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Gender-based discrimination and son preference in Punjabi-Canadian families: a community-based participatory qualitative research study.

    Wanigaratne, Susitha / Januwalla, Alia / Bhangu, Manvir / Uppal, Pamela / Kumar-Ratta, Amrita / Brar, Amanpreet / Dennis, Cindy-Lee / Urquia, Marcelo

    BMJ open

    2023  Volume 13, Issue 8, Page(s) e074276

    Abstract: Objectives: To conduct a qualitative study, guided by the principles of community-based participatory research, with the following objectives: (1) to provide a conceptual framework describing the drivers of son preference; (2) to understand experiences ... ...

    Abstract Objectives: To conduct a qualitative study, guided by the principles of community-based participatory research, with the following objectives: (1) to provide a conceptual framework describing the drivers of son preference; (2) to understand experiences of son preference among Punjabi-Canadians and (3) with this understanding, identify and co-design an appropriate educational tool.
    Design, setting, participants, methods: Qualitative study consisting of four bilingual (Punjabi and English) focus group discussions with 11 mothers, 4 fathers and 17 grandmothers in Toronto and Brampton, Canada. Participants were queried about experiences and perspectives related to reproductive decision-making, gender equity and son preference, and for appropriate approaches to reducing inequities. Transcripts were simultaneously translated and written in English and thematic analysis was conducted. An infoposter was identified as a feasible educational tool and was co-designed by researchers and community partners.
    Results: Participants identified patrilocality (ie, married sons reside with parents, married daughters with in-laws) and patrilineality (ie, sons inherit assets, daughters' husband receives a dowry) as structural precursors to proximal drivers (ie, old-age security) of son preference. Mothers' and grandmothers' value to their families depended strongly on having a son but did not guarantee security. Pressures (ie, internalised discrimination, reproductive coercion) to conceive a son were common after the birth of at least one daughter in the absence of sons. Participants did not know anyone who had a sex selective abortion in Canada; however, traditional sex selection methods (eg, herbal medicines) were mentioned. Our co-designed infoposter entitled 'Truths About Son Preference' addressed three misconceptions identified in discussions.
    Conclusion: This study may be useful to health and social care providers in providing structurally competent and culturally humble counselling and care, particularly after the birth of daughters in the absence of sons. Community engagement is necessary for future intervention development.
    MeSH term(s) Female ; Pregnancy ; Humans ; Nuclear Family ; Community-Based Participatory Research ; Canada ; Parents ; Mothers
    Language English
    Publishing date 2023-08-30
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2023-074276
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Navigating the Impact of the Dobbs Decision: Perspectives from Pediatric Surgeons on Reproductive Health Care.

    Brar, Amanpreet / Mannava, Sindhu V / Patwardhan, Utsav M / Sullins, Veronica F / Berdan, Elizabeth A / Greves, Cole D / Gow, Kenneth W / Carlisle, Erica / Tsao, KuoJen / Hunter, Catherine / Baerg, Joanne E / Knod, J Leslie

    Journal of the American College of Surgeons

    2024  

    Abstract: Summary: Nationwide abortion restrictions resulting from the Dobbs v. Jackson Women's Health Organization (2022) decision have generated confusion and uncertainty among healthcare professionals, with concerns for liability impacting clinical decision- ... ...

    Abstract Summary: Nationwide abortion restrictions resulting from the Dobbs v. Jackson Women's Health Organization (2022) decision have generated confusion and uncertainty among healthcare professionals, with concerns for liability impacting clinical decision-making and outcomes. The impact on pediatric surgery can be seen in prenatal counseling for fetal anomaly cases, counseling for fetal intervention, and recommendations for pregnant children and adolescents who seek termination. It is essential that all physicians and healthcare team members understand the legal implications on their clinical practices, engage with resources and organizations which can help navigate these circumstances, and consider advocating for patients and themselves. Pediatric surgeons must consider the impact of these changing laws on their ability to provide comprehensive and ethical care and counseling to all patients.
    Language English
    Publishing date 2024-04-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1181115-8
    ISSN 1879-1190 ; 1072-7515
    ISSN (online) 1879-1190
    ISSN 1072-7515
    DOI 10.1097/XCS.0000000000001092
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article: Surgical removal of venous filter and snare complex in a patient with solitary left pelvic kidney.

    Gupta, Vaibhav / Brar, Amanpreet / Pope, Marc

    Journal of vascular surgery cases and innovative techniques

    2018  Volume 4, Issue 3, Page(s) 201–203

    Abstract: Anticoagulation is used to prevent thromboembolism; inferior vena cava filters are an alternative in patients with contraindications to anticoagulation. Although it is safe and effective, there are recognized complications related to inferior vena cava ... ...

    Abstract Anticoagulation is used to prevent thromboembolism; inferior vena cava filters are an alternative in patients with contraindications to anticoagulation. Although it is safe and effective, there are recognized complications related to inferior vena cava filter placement. We describe the case of a young man with congenital solitary left pelvic kidney who required unique filter placement to suit the anatomy and surgical removal after entrapment of the filter-snare complex in the left internal iliac vein. Patients may also acquire solitary pelvic kidneys after renal transplantation. This anatomy poses unique challenges to venous filter placement and requires tailored management.
    Language English
    Publishing date 2018-08-17
    Publishing country United States
    Document type Case Reports
    ISSN 2468-4287
    ISSN 2468-4287
    DOI 10.1016/j.jvscit.2018.04.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Tumor Budding Assessment in Colorectal Carcinoma: Normalization Revisited.

    Cyr, David P / Pun, Cherry / Shivji, Sameer / Mitrovic, Bojana / Duan, Kai / Tomin, Rossi / Sari, Aysegul / Brar, Amanpreet / Zerhouni, Siham / Brar, Mantaj S / Kennedy, Erin D / Swallow, Carol J / Kirsch, Richard / Conner, James R

    The American journal of surgical pathology

    2023  Volume 48, Issue 3, Page(s) 251–265

    Abstract: Tumor budding (TB) is a powerful prognostic factor in colorectal cancer (CRC). An internationally standardized method for its assessment (International Tumor Budding Consensus Conference [ITBCC] method) has been adopted by most CRC pathology protocols. ... ...

    Abstract Tumor budding (TB) is a powerful prognostic factor in colorectal cancer (CRC). An internationally standardized method for its assessment (International Tumor Budding Consensus Conference [ITBCC] method) has been adopted by most CRC pathology protocols. This method requires that TB counts are reported by field area (0.785 mm 2 ) rather than objective lens and a normalization factor is applied for this purpose. However, the validity of this approach is yet to be tested. We sought to validate the ITBCC method with a particular emphasis on normalization as a tool for standardization. In a cohort of 365 stage I-III CRC, both normalized and non-normalized TB were significantly associated with disease-specific survival and recurrence-free survival ( P <0.0001). Examining both 0.95 and 0.785 mm 2 field areas in a subset of patients (n=200), we found that normalization markedly overcorrects TB counts: Counts obtained in a 0.95 mm 2 hotspot field were reduced by an average of 17.5% following normalization compared with only 3.8% when counts were performed in an actual 0.785 mm 2 field. This resulted in 45 (11.3%) cases being downgraded using ITBCC grading criteria following normalization, compared with only 5 cases (1.3%, P =0.0007) downgraded when a true 0.785 mm 2 field was examined. In summary, the prognostic value of TB was retained regardless of whether TB counts in a 0.95 mm 2 field were normalized. Normalization resulted in overcorrecting TB counts with consequent downgrading of most borderline cases. This has implications for risk stratification and adjuvant treatment decisions, and suggests the need to re-evaluate the role of normalization in TB assessment.
    MeSH term(s) Humans ; Neoplasm Staging ; Prognosis ; Neoplasm Grading ; Colorectal Neoplasms/pathology ; Consensus
    Language English
    Publishing date 2023-12-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 752964-8
    ISSN 1532-0979 ; 0147-5185
    ISSN (online) 1532-0979
    ISSN 0147-5185
    DOI 10.1097/PAS.0000000000002166
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Management of pediatric appendiceal carcinoid: a single institution experience from 5000 appendectomies.

    Ranaweera, Chirath / Brar, Amanpreet / Somers, Gino R / Sheikh, Furqan / Pierro, Agostino / Zani, Augusto

    Pediatric surgery international

    2019  Volume 35, Issue 12, Page(s) 1427–1430

    Abstract: Aim of the study: Appendiceal carcinoid (neuroendocrine tumor or NET) is a rare neuroendocrine neoplasm often found incidentally following appendectomy for appendicitis. Surgery for appendicitis is currently under scrutiny and children are increasingly ... ...

    Abstract Aim of the study: Appendiceal carcinoid (neuroendocrine tumor or NET) is a rare neuroendocrine neoplasm often found incidentally following appendectomy for appendicitis. Surgery for appendicitis is currently under scrutiny and children are increasingly managed conservatively with antibiotics alone. Herein, we aimed to review our experience with the management of appendiceal carcinoids at our institution.
    Methods: Following ethical approval, we reviewed the charts of all patients who underwent appendectomy for appendicitis at our institution between 2000 and 2018. The pathology registry was consulted to identify children diagnosed with appendiceal carcinoid. Outcome measures included incidence, demographics, and management.
    Main results: During the study period, 32 children (23 female) had an appendiceal carcinoid confirmed at pathology. Of these, 13 were initially treated with appendectomy (total of 5,059 appendectomies: 0.3% incidence). The other 19 had an appendectomy elsewhere by an adult general surgeon and were referred to our institution for further management. Overall, the mean age at diagnosis was 13 ± 2.7 years and all patient had a preoperative diagnosis of appendicitis, none of suspected carcinoid. Most children (75%) had acute non-perforated appendicitis. The overall mean size of the lesion was 1 ± 0.9 cm, with a > 2 cm lesion in 3 patients. Following diagnosis, 12 children (38%) underwent an ileocolic resection, due to carcinoid size, invasiveness, and margin clearance.
    Conclusions: In our cohort, the incidence of appendiceal carcinoid among children with appendicitis is very low. Most carcinoids are small, located at the tip, associated with non-perforated appendicitis, and present in girls. Most were treated with appendectomy alone, with more extensive surgery performed in one third of children.
    MeSH term(s) Adolescent ; Appendectomy ; Appendiceal Neoplasms/epidemiology ; Appendiceal Neoplasms/pathology ; Appendiceal Neoplasms/surgery ; Appendicitis/epidemiology ; Appendicitis/surgery ; Carcinoid Tumor/epidemiology ; Carcinoid Tumor/pathology ; Carcinoid Tumor/surgery ; Child ; Child, Preschool ; Cohort Studies ; Comorbidity ; Female ; Humans ; Incidence ; Infant ; Male ; Retrospective Studies
    Language English
    Publishing date 2019-09-25
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 632773-4
    ISSN 1437-9813 ; 0179-0358
    ISSN (online) 1437-9813
    ISSN 0179-0358
    DOI 10.1007/s00383-019-04575-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Lived experiences of Asian Canadians encountering discrimination during the COVID-19 pandemic: a qualitative interview study.

    Leigh, Jeanna Parsons / Moss, Stephana Julia / Tiifu, Faizah / FitzGerald, Emily / Brundin-Mathers, Rebecca / Dodds, Alexandra / Brar, Amanpreet / de Grood, Chloe Moira / Stelfox, Henry T / Fiest, Kirsten M / Ng-Kamstra, Josh

    CMAJ open

    2022  Volume 10, Issue 2, Page(s) E539–E545

    Abstract: Background: Asian Canadians have experienced increased cases of racialized discrimination after the first emergence of SARS-CoV-2 in China. This study examined how the COVID-19 pandemic has affected Asian Canadians' sense of safety and belonging in ... ...

    Abstract Background: Asian Canadians have experienced increased cases of racialized discrimination after the first emergence of SARS-CoV-2 in China. This study examined how the COVID-19 pandemic has affected Asian Canadians' sense of safety and belonging in their Canadian (i.e., geographical) communities.
    Methods: We applied a qualitative description study design in which semistructured interviews were conducted from Mar. 23 to May 27, 2021. Purposive and snowball sampling methods were used to recruit Asian Canadians diverse in region, gender and age. Interviews were conducted through Zoom videoconference or telephone, and independent qualitative thematic analysis in duplicate was used to derive primary themes and subthemes.
    Results: Thirty-two Asian Canadians (median age 35 [interquartile range 24-46] yr, 56% female, 44% East Asian) participated in the study. We identified 5 predominant themes associated with how the COVID-19 pandemic affected the participants' sense of security and belonging to their communities: relation between socioeconomic status (SES) and exposure to discrimination (i.e., how SES insulates or exposes individuals to increased discrimination); politics, media and the COVID-19 pandemic (i.e., the key role that politicians and media played in enabling spread of discrimination against and fear of Asian people); effect of discrimination on mental and social health (i.e., people's ability to interact and form meaningful relationships with others); coping with the impact of discrimination (i.e., the way people appraise and move forward in identity-threatening situations); and implications for sense of safety and sense of belonging (i.e., people feeling unable to safely use public spaces in person, including the need to remain alert in anticipation of harm, leading to distress and exhaustion).
    Interpretation: During the COVID-19 pandemic, Asian Canadians in our study felt unsafe owing to the uncertain, unexpected and unpredictable nature of discrimination, but also felt a strong sense of belonging to Canadian society and felt well connected to their Asian Canadian communities. Future work should seek to explore the influence of social media on treatment of and attitudes toward Asian Canadians.
    MeSH term(s) Adult ; COVID-19/epidemiology ; Canada/epidemiology ; Female ; Humans ; Male ; Pandemics ; Qualitative Research ; SARS-CoV-2
    Language English
    Publishing date 2022-06-14
    Publishing country Canada
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2701622-5
    ISSN 2291-0026 ; 2291-0026
    ISSN (online) 2291-0026
    ISSN 2291-0026
    DOI 10.9778/cmajo.20220019
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top