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  1. AU="Braun, W."
  2. AU="Duvall, Julia B."
  3. AU=Basu Sanjay
  4. AU="Keivani, A." AU="Keivani, A."
  5. AU="Delwig, Anton"
  6. AU="Lei, Yuanyuan"
  7. AU="Ahmed, Osmanuddin"
  8. AU="López, F. J. L."
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  1. Book: Laborwerte im Klartext

    Braun, Wolfgang

    Untersuchungsmethoden und Befund verständlich gemacht

    (Humboldt-Taschenbuch ; 789 : Gesundheit & Medizin)

    2005  

    Author's details von Wolfgang Braun
    Series title Humboldt-Taschenbuch ; 789 : Gesundheit & Medizin
    Humboldt-Taschenbücher
    Collection Humboldt-Taschenbücher
    Keywords Labormedizin
    Subject Labordiagnostik ; Medizinische Labortechnik ; Laboratoriumsdiagnostik ; Laboratoriumsmedizin
    Language German
    Size 140 S., Ill., graph. Darst., 18 cm
    Edition 2., vollst. aktualisierte Aufl.
    Publisher Humboldt
    Publishing place Baden-Baden
    Publishing country Germany
    Document type Book
    HBZ-ID HT014100656
    ISBN 3-89994-879-3 ; 978-3-89994-879-0
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2005 A 6474 order for loan Magazin

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  2. Article ; Online: High-frequency oscillations and sequence generation in two-population models of hippocampal region CA1.

    Braun, Wilhelm / Memmesheimer, Raoul-Martin

    PLoS computational biology

    2022  Volume 18, Issue 2, Page(s) e1009891

    Abstract: Hippocampal sharp wave/ripple oscillations are a prominent pattern of collective activity, which consists of a strong overall increase of activity with superimposed (140 - 200 Hz) ripple oscillations. Despite its prominence and its experimentally ... ...

    Abstract Hippocampal sharp wave/ripple oscillations are a prominent pattern of collective activity, which consists of a strong overall increase of activity with superimposed (140 - 200 Hz) ripple oscillations. Despite its prominence and its experimentally demonstrated importance for memory consolidation, the mechanisms underlying its generation are to date not understood. Several models assume that recurrent networks of inhibitory cells alone can explain the generation and main characteristics of the ripple oscillations. Recent experiments, however, indicate that in addition to inhibitory basket cells, the pattern requires in vivo the activity of the local population of excitatory pyramidal cells. Here, we study a model for networks in the hippocampal region CA1 incorporating such a local excitatory population of pyramidal neurons. We start by investigating its ability to generate ripple oscillations using extensive simulations. Using biologically plausible parameters, we find that short pulses of external excitation triggering excitatory cell spiking are required for sharp/wave ripple generation with oscillation patterns similar to in vivo observations. Our model has plausible values for single neuron, synapse and connectivity parameters, random connectivity and no strong feedforward drive to the inhibitory population. Specifically, whereas temporally broad excitation can lead to high-frequency oscillations in the ripple range, sparse pyramidal cell activity is only obtained with pulse-like external CA3 excitation. Further simulations indicate that such short pulses could originate from dendritic spikes in the apical or basal dendrites of CA1 pyramidal cells, which are triggered by coincident spike arrivals from hippocampal region CA3. Finally we show that replay of sequences by pyramidal neurons and ripple oscillations can arise intrinsically in CA1 due to structured connectivity that gives rise to alternating excitatory pulse and inhibitory gap coding; the latter denotes phases of silence in specific basket cell groups, which induce selective disinhibition of groups of pyramidal neurons. This general mechanism for sequence generation leads to sparse pyramidal cell and dense basket cell spiking, does not rely on synfire chain-like feedforward excitation and may be relevant for other brain regions as well.
    MeSH term(s) Action Potentials/physiology ; CA1 Region, Hippocampal ; CA3 Region, Hippocampal ; Dendrites/physiology ; Hippocampus/physiology ; Neurons/physiology ; Pyramidal Cells/physiology ; Synapses
    Language English
    Publishing date 2022-02-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2193340-6
    ISSN 1553-7358 ; 1553-734X
    ISSN (online) 1553-7358
    ISSN 1553-734X
    DOI 10.1371/journal.pcbi.1009891
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Conference proceedings: Die Nutzung der Ressource "Synergie"

    Braun, Waldemar

    Zukunftssicherung für Forschung, Marketing und Vertrieb

    (IFE interdisciplinary science & practice ; 7)

    1998  

    Institution Symposium Die Nutzung der Ressource Synergie
    Author's details [Das Symposium "Die Nutzung der Ressource Synergie"]. W. Braun ... (Hrsg.)
    Series title IFE interdisciplinary science & practice ; 7
    Collection
    Language English ; German
    Size 208 S. : graph. Darst.
    Publisher Univ. Witten/Herdecke Verl.-Ges
    Publishing place Witten
    Document type Book ; Conference proceedings
    Note Beitr. teilw. engl., teilw. dt.
    HBZ-ID HT011106650
    ISBN 3-9804761-7-0 ; 3-9804761-1-1 ; 978-3-9804761-7-1 ; 978-3-9804761-1-9
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1999 A 6122 order for loan Magazin

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  4. Book: Gesundheitswesen 2010

    Braun, Waldemar

    Prognosen, Trends und Chancen

    (IFE interdisciplinary science & practice ; 6)

    1998  

    Author's details W. Braun ... (Hrsg.)
    Series title IFE interdisciplinary science & practice ; 6
    Collection
    Language English ; German
    Size 162 S. : graph. Darst.
    Publisher Univ. Witten/Herdecke Verl.-Ges
    Publishing place Witten
    Document type Book
    Note Beitr. teilw. engl., teilw. dt.
    HBZ-ID HT009515932
    ISBN 3-9804761-6-2 ; 978-3-9804761-6-4
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1999 A 6 order for loan Magazin

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  5. Article: TEA Laser Induced Multiphoton Dissociation of Ethylene in a Collisional Regime: Model and Experiment.

    Peterson, N C / Manning, R G / Braun, W

    Journal of research of the National Bureau of Standards (1977)

    2021  Volume 83, Issue 2, Page(s) 117–125

    Abstract: The focused beam of a pulsed ... ...

    Abstract The focused beam of a pulsed CO
    Language English
    Publishing date 2021-06-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2602408-1
    ISSN 0160-1741 ; 0034-530X ; 0091-0635
    ISSN 0160-1741 ; 0034-530X ; 0091-0635
    DOI 10.6028/jres.083.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The updated Structural Database of Allergenic Proteins (SDAP 2.0) provides 3D models for allergens and incorporated bioinformatics tools.

    Negi, Surendra S / Schein, Catherine H / Braun, Werner

    The journal of allergy and clinical immunology. Global

    2023  Volume 2, Issue 4, Page(s) 100162

    Abstract: Background: Allergenic proteins can cause IgE-mediated adverse reactions in sensitized individuals. Although the sequences of many allergenic proteins have been identified, bioinformatics data analysis with advanced computational methods and modeling is ...

    Abstract Background: Allergenic proteins can cause IgE-mediated adverse reactions in sensitized individuals. Although the sequences of many allergenic proteins have been identified, bioinformatics data analysis with advanced computational methods and modeling is needed to identify the basis for IgE binding and cross-reactivity.
    Objective: We aim to present the features and use of the updated Structural Database of Allergenic Proteins 2.0 (SDAP 2.0) webserver, a unique, publicly available resource to compare allergens using specially designed computational tools and new high-quality 3-D models for most known allergens.
    Methods: Previously developed and novel software tools for identifying cross-reactive allergens using sequence and structure similarity are implemented in SDAP 2.0. A comprehensive set of high-quality 3-D models of most allergens was generated with the state-of-the-art AlphaFold 2 software. A graphics tool enables the interactive visualization of IgE epitopes on experimentally determined and modeled 3-D structures.
    Results: A user can search for allergens similar to a given input sequence with the FASTA algorithm or the window-based World Health Organization/International Union of Immunological Societies (WHO/IUIS) guidelines on safety concerns of novel food products. Peptides similar to known IgE epitopes can be identified with the property distance tool and conformational epitopes by the Cross-React method. The updated database contains 1657 manually curated sequences including all allergens from the IUIS database, 334 experimentally determined X-ray or NMR structures, and 1565 3-D models. Each allergen/isoallergen is classified according to its protein family.
    Conclusions: SDAP provides access to the steadily increasing information on allergenic structures and epitopes with integrated bioinformatics tools to identify and analyze their similarities. In addition to serving the research and regulatory community, it provides clinicians with tools to identify potential coallergies in a sensitive patient and can help companies to design hypoallergenic foods and immunotherapies.
    Language English
    Publishing date 2023-08-11
    Publishing country United States
    Document type Journal Article
    ISSN 2772-8293
    ISSN (online) 2772-8293
    DOI 10.1016/j.jacig.2023.100162
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Conference proceedings: Qualitätssicherung, Pharmakoökonomie und Disease Management

    Braun, Waldemar

    Berichtsband zum 3. Symposium

    (IFE interdisciplinary science & practice ; 4)

    1996  

    Title variant Disease Management
    Author's details W. Braun ... (Hrsg.)
    Series title IFE interdisciplinary science & practice ; 4
    Collection
    Keywords Disease Management / congresses ; Deutschland ; Gesundheitswesen ; Qualitätsmanagement ; Disease Management
    Subject Krankheitsmanagement ; Disease Management Programme ; DMP ; Regulierte Krankenversorgung ; Quality Management ; Total Quality Management ; Unternehmen ; TQM ; Qualitätssicherungssystem ; Qualitätsmanagementsystem ; Umfassendes Qualitätsmanagement ; QM-System ; Gesundheitsdienst ; Gesundheitssystem ; Gesundheitswirtschaft ; Medizinalwesen ; Medizinalsystem
    Language German ; English
    Size 282 S. : Ill., graph. Darst.
    Publisher Univ. Witten/Herdecke Verl.-Ges. mbH
    Publishing place Witten
    Document type Book ; Conference proceedings
    Note Beitr. teilw. engl., teilw. dt.
    HBZ-ID HT007909398
    ISBN 3-9804761-3-8 ; 3-9804761-1-1 ; 978-3-9804761-3-3 ; 978-3-9804761-1-9
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1998 A 172 order for loan Magazin

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  8. Book ; Conference proceedings: Qualitätssicherung in Diagnostik und Therapie am Beispiel der Demenzerkrankungen

    Braun, Waldemar

    Berichtsband zum Methodenforum im November 1995 [Witten]

    (IFE interdisciplinary science & practice ; 3)

    1996  

    Event/congress Methodenforum (1995, Witten)
    Author's details W. Braun ... (Hrsg.)
    Series title IFE interdisciplinary science & practice ; 3
    Collection
    Keywords Dementia / diagnosis / congresses ; Dementia / therapy / congresses ; Quality Assurance, Health Care / congresses
    Language German
    Size 199 S. : graph. Darst.
    Publisher Univ. Witten/Herdecke Verl.-Ges
    Publishing place Witten
    Document type Book ; Conference proceedings
    HBZ-ID HT007549210
    ISBN 3-9804761-4-6 ; 978-3-9804761-4-0
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1997 A 4616 order for loan Magazin

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  9. Article ; Online: Long-Range Atomic Order on Double-Stepped Al

    Smink, Sander / Majer, Lena N / Boschker, Hans / Mannhart, Jochen / Braun, Wolfgang

    Advanced materials (Deerfield Beach, Fla.)

    2024  , Page(s) e2312899

    Abstract: The deterministic preparation of highly ordered single-crystalline surfaces is a key step for studying and utilizing the physical properties of various advanced materials. This paper presents the fast and straightforward preparation of vicinal ... ...

    Abstract The deterministic preparation of highly ordered single-crystalline surfaces is a key step for studying and utilizing the physical properties of various advanced materials. This paper presents the fast and straightforward preparation of vicinal Al
    Language English
    Publishing date 2024-03-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1474949-X
    ISSN 1521-4095 ; 0935-9648
    ISSN (online) 1521-4095
    ISSN 0935-9648
    DOI 10.1002/adma.202312899
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Dissociation in Brucella abortus; a demonstration of the role of inherent and environmental factors in bacterial variation.

    BRAUN, W

    Journal of bacteriology

    2010  Volume 51, Page(s) 327–349

    MeSH term(s) Bacteria ; Brucella abortus ; Brucellosis
    Language English
    Publishing date 2010-09-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2968-3
    ISSN 1098-5530 ; 0021-9193
    ISSN (online) 1098-5530
    ISSN 0021-9193
    DOI 10.1128/JB.51.3.327-349.1946
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ud II Zs.50: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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