Article ; Online: Mechanical Tensions Regulate Gene Expression in the
International journal of molecular sciences
2024 Volume 25, Issue 2
Abstract: During gastrulation and neurulation, the chordamesoderm and overlying neuroectoderm of vertebrate embryos converge under the control of a specific genetic programme to the dorsal midline, simultaneously extending along it. However, whether mechanical ... ...
| Abstract | During gastrulation and neurulation, the chordamesoderm and overlying neuroectoderm of vertebrate embryos converge under the control of a specific genetic programme to the dorsal midline, simultaneously extending along it. However, whether mechanical tensions resulting from these morphogenetic movements play a role in long-range feedback signaling that in turn regulates gene expression in the chordamesoderm and neuroectoderm is unclear. In the present work, by using a model of artificially stretched explants of |
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| MeSH term(s) | Animals ; Stress, Mechanical ; Xenopus laevis/genetics ; 4-Butyrolactone ; Gene Expression |
| Chemical Substances | A-factor (Streptomyces) (51311-41-2) ; 4-Butyrolactone (OL659KIY4X) |
| Language | English |
| Publishing date | 2024-01-10 |
| Publishing country | Switzerland |
| Document type | Journal Article |
| ZDB-ID | 2019364-6 |
| ISSN | 1422-0067 ; 1422-0067 ; 1661-6596 |
| ISSN (online) | 1422-0067 |
| ISSN | 1422-0067 ; 1661-6596 |
| DOI | 10.3390/ijms25020870 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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