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  1. Book: Physiologie der Haustiere

    Breves, Gerhard / Diener, Martin / Gäbel, Gotthold

    2022  

    Author's details herausgegeben von Gerhard Breves, Martin Diener, Gotthold Gäbel
    Keywords Haustiere ; Physiologie
    Subject Humanphysiologie ; Mensch ; Körperfunktion ; Haustier
    Language German
    Size 686 Seiten, Illustrationen, 27 cm x 19.5 cm
    Edition 6., vollständig überarbeitete und erweiterte Auflage
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    HBZ-ID HT021207324
    ISBN 978-3-13-243835-4 ; 3-13-243835-9 ; 9783132438361 ; 9783132438378 ; 3132438367 ; 3132438375
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    224/23 available for loan (reading room) Freihandmagazin (U1)
    Zugang zur Online-Ausgabe über Code aus lizenzrechtlichen Gründen nicht möglich

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  2. Article: Postnatal development of salivary phosphate, sodium and potassium secretion in calves.

    Muscher-Banse, Alexandra S / Daenicke, Reinhard / Dänicke, Sven / Breves, Gerhard

    Frontiers in veterinary science

    2023  Volume 10, Page(s) 1294899

    Abstract: The transition of young lambs and calves from a non-ruminating to a ruminating animal include substantial, developmental changes to alter saliva production. Due to the simultaneous development of the forestomach system, the salivary glands must transfer ... ...

    Abstract The transition of young lambs and calves from a non-ruminating to a ruminating animal include substantial, developmental changes to alter saliva production. Due to the simultaneous development of the forestomach system, the salivary glands must transfer more and more substances such as bicarbonate and phosphate (Pi), but also sodium (Na), into saliva in order to create and to maintain optimal environmental conditions for microbial metabolism. The objective of the present study was to characterize the effects of different dietary energy levels on the ability of the salivary glands to concentrate minerals in young ruminants in more detail during the first 7 weeks of life. Blood and saliva samples were collected from twelve female calves of the German Holstein breed fed different levels of milk replacer. Plasma and saliva samples were collected over 7 weeks postpartum and Na, Pi and potassium (K) concentrations were measured. Salivary Na and Pi concentrations (
    Language English
    Publishing date 2023-12-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2834243-4
    ISSN 2297-1769
    ISSN 2297-1769
    DOI 10.3389/fvets.2023.1294899
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: XIIIth International symposium on ruminant physiology.

    Breves, Gerhard / Gäbel, Gotthold

    Animal : an international journal of animal bioscience

    2020  Volume 14, Issue S1, Page(s) s1

    Language English
    Publishing date 2020-02-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2257920-5
    ISSN 1751-732X ; 1751-7311
    ISSN (online) 1751-732X
    ISSN 1751-7311
    DOI 10.1017/S1751731119003471
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 7718: Show issues

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  4. Book ; Online ; Thesis: Funktionsstörungen der Eustachischen Röhre

    Oppel, Niels Martin [Verfasser] / Bleich, André [Akademischer Betreuer] / Breves, Gerhard [Gutachter]

    Entwicklung eines Tiermodells sowie ein Beitrag zur endoluminalen Diagnostik

    2023  

    Author's details Niels Martin Oppel ; Gutachter: Gerhard Breves ; Betreuer: André Bleich
    Keywords Landwirtschaft, Veterinärmedizin ; Agriculture, Veterinary Science
    Subject code sg630
    Language German
    Publisher Stiftung Tierärztliche Hochschule Hannover
    Publishing place Hannover
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

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  5. Article ; Online: Postnatal Development of Salivary Phosphate, Sodium and Potassium Secretion in Calves

    Muscher-Banse, Alexandra S. / Dänicke, Reinhard / Dänicke, Sven / Breves, Gerhard

    2023  

    Abstract: The transition of young lambs and calves from a non-ruminating to a ruminating animal include substantial, developmental changes to alter saliva production. Due to the simultaneous development of the forestomach system, the salivary glands must transfer ... ...

    Abstract The transition of young lambs and calves from a non-ruminating to a ruminating animal include substantial, developmental changes to alter saliva production. Due to the simultaneous development of the forestomach system, the salivary glands must transfer more and more substances such as bicarbonate and phosphate (Pi), but also sodium (Na), into saliva in order to create and to maintain optimal environmental conditions for microbial metabolism. The objective of the present study was to characterize the effects of different dietary energy levels on the ability of the salivary glands to concentrate minerals in young ruminants in more detail during the first seven weeks of life. Blood and saliva samples were collected from twelve female calves of the German Holstein breed fed different levels of milk replacer. Plasma and saliva samples were collected over seven weeks postpartum and Na, Pi and potassium (K) concentrations were measured. Salivary Na and Pi concentrations (P < 0.001) increased as a function of time and were not affected by varying energy intake, while K concentration (P < 0.001) decreased over the developmental period and was also not affected by energy intake. This suggests that the ability to specifically concentrate minerals such as Na and Pi in saliva follows a genetic program in the salivary glands rather than being influenced by dietary factors such as energy intake in young ruminants.
    Keywords Text ; article ; ddc:630 ; Phosphate -- Potassium -- Ruminant -- Saliva -- salivary gland -- Sodium
    Subject code 630
    Language English
    Publishing date 2023-12-19
    Publishing country de
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  6. Article ; Online: Resveratrol Inhibits Porcine Intestinal Glucose and Alanine Transport: Potential Roles of Na⁺/K⁺-ATPase Activity, Protein Kinase A, AMP-Activated Protein Kinase and the Association of Selected Nutrient Transport Proteins with Detergent Resistant Membranes.

    Klinger, Stefanie / Breves, Gerhard

    Nutrients

    2018  Volume 10, Issue 3

    Abstract: Background: Beneficial effects of Resveratrol (RSV) have been demonstrated, including effects on transporters and channels. However, little is known about how RSV influences intestinal transport. The aim of this study was to further characterize the ... ...

    Abstract Background: Beneficial effects of Resveratrol (RSV) have been demonstrated, including effects on transporters and channels. However, little is known about how RSV influences intestinal transport. The aim of this study was to further characterize the effects of RSV on intestinal transport and the respective mechanisms.
    Methods: Porcine jejunum and ileum were incubated with RSV (300 µM, 30 min) in Ussing chambers (functional studies) and tissue bathes (detection of protein expression, phosphorylation, association with detergent resistant membranes (DRMs)).
    Results: RSV reduced alanine and glucose-induced short circuit currents (ΔI
    Conclusion: RSV influences the intestinal transport of glucose, alanine and chloride and is likely to affect other transport processes. As the effects of protein kinase activation vary between the intestinal localizations, it would appear that increasing cyclic adenosine monophosphate (cAMP) levels are part of the mechanism. Nonetheless, the physiological responses depend on cell type-specific structures.
    MeSH term(s) AMP-Activated Protein Kinases/metabolism ; Alanine/metabolism ; Animals ; Cell Membrane/drug effects ; Cell Membrane/enzymology ; Chlorides/metabolism ; Cyclic AMP/metabolism ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Glucose/metabolism ; Ileum/drug effects ; Ileum/enzymology ; In Vitro Techniques ; Ion Pumps/metabolism ; Jejunum/drug effects ; Jejunum/enzymology ; Membrane Potentials ; Peptide Transporter 1/metabolism ; Phosphorylation ; Sodium-Glucose Transporter 1/metabolism ; Sodium-Hydrogen Exchanger 3/metabolism ; Sodium-Potassium-Exchanging ATPase/metabolism ; Stilbenes/pharmacology ; Sus scrofa
    Chemical Substances Chlorides ; Ion Pumps ; Peptide Transporter 1 ; Sodium-Glucose Transporter 1 ; Sodium-Hydrogen Exchanger 3 ; Stilbenes ; Cyclic AMP (E0399OZS9N) ; Cyclic AMP-Dependent Protein Kinases (EC 2.7.11.11) ; AMP-Activated Protein Kinases (EC 2.7.11.31) ; Sodium-Potassium-Exchanging ATPase (EC 3.6.3.9) ; Glucose (IY9XDZ35W2) ; Alanine (OF5P57N2ZX) ; resveratrol (Q369O8926L)
    Language English
    Publishing date 2018-03-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu10030302
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Thesis: Phosphor- und Calciumumsatz sowie Flüssigkeitspassage und mikrobielle Verdauungsvorgänge im Gastrointestinaltrakt von Schafen in einer experimentellen P-Depletion

    Breves, Gerhard

    1986  

    Author's details Gerhard Breves
    Size 124 S. : graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Hannover, Tierärztl. Hochsch., Diss., 1986
    HBZ-ID HT004178438
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    AY 11142 order for loan Geschlossenes Magazin (U2)

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  8. Article ; Online: Alterations in fermentation parameters during and after induction of a subacute rumen acidosis in the rumen simulation technique.

    Orton, Theresa / Rohn, Karl / Breves, Gerhard / Brede, Melanie

    Journal of animal physiology and animal nutrition

    2020  Volume 104, Issue 6, Page(s) 1678–1689

    Abstract: Subacute rumen acidosis (SARA) is a common problem in dairy cattle. High-concentrate rations lead to an accumulation of short-chain fatty acids (SCFA) in the rumen and a subsequent decrease in ruminal pH. As SARA impairs animal welfare and productivity, ... ...

    Abstract Subacute rumen acidosis (SARA) is a common problem in dairy cattle. High-concentrate rations lead to an accumulation of short-chain fatty acids (SCFA) in the rumen and a subsequent decrease in ruminal pH. As SARA impairs animal welfare and productivity, numerous in vivo studies are focusing on evaluation of prevention strategies. In vitro models can support this research and reduce animal numbers and experimental costs. We used different diets and buffer compositions to induce SARA in the rumen simulation technique (Rusitec) and investigated the recovery process. The experiment consisted of an equilibration period (7 days), a first control period, a SARA period and a second control period (5 days each). During the SARA period, SARA was induced by infusing SARA1 or SARA2 buffer with reduced bicarbonate (20 mmol/L and 25 mmol/L) and phosphate (both 10 mmol/L) contents compared to a modified McDougall's buffer (bicarbonate 97.9 mmol/L, phosphates 20 mmol/L). Additionally, we compared three feeding strategies, which differed in the concentrate-to-roughage ratio (30:70, 70:30, changing ratio: 30% concentrate in control periods and 70% concentrate in SARA period). During the SARA period, the pH decreased to a constant value below the SARA thresholds of pH 5.8 and 5.6, whereas lactate concentrations remained low. The total SCFA production rate declined 3 days after SARA induction, and the molar proportion of acetate decreased. The decrease in pH and SCFA production was more pronounced for SARA1 buffer. The high-concentrate diet reduced the molar proportion of acetate and increased NH
    MeSH term(s) Acidosis/veterinary ; Animals ; Cattle ; Cattle Diseases/metabolism ; Diet/veterinary ; Female ; Fermentation ; Hydrogen-Ion Concentration ; Lactation ; Rumen/metabolism
    Language English
    Publishing date 2020-06-28
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 232729-6
    ISSN 1439-0396 ; 0044-3565 ; 0931-2439
    ISSN (online) 1439-0396
    ISSN 0044-3565 ; 0931-2439
    DOI 10.1111/jpn.13412
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 17: Show issues

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  9. Article: Alterations in fermentation parameters during and after induction of a subacute rumen acidosis in the rumen simulation technique

    Orton, Theresa / Rohn, Karl / Breves, Gerhard / Brede, Melanie

    Journal of animal physiology and animal nutrition. 2020 Nov., v. 104, no. 6

    2020  

    Abstract: Subacute rumen acidosis (SARA) is a common problem in dairy cattle. High‐concentrate rations lead to an accumulation of short‐chain fatty acids (SCFA) in the rumen and a subsequent decrease in ruminal pH. As SARA impairs animal welfare and productivity, ... ...

    Abstract Subacute rumen acidosis (SARA) is a common problem in dairy cattle. High‐concentrate rations lead to an accumulation of short‐chain fatty acids (SCFA) in the rumen and a subsequent decrease in ruminal pH. As SARA impairs animal welfare and productivity, numerous in vivo studies are focusing on evaluation of prevention strategies. In vitro models can support this research and reduce animal numbers and experimental costs. We used different diets and buffer compositions to induce SARA in the rumen simulation technique (Rusitec) and investigated the recovery process. The experiment consisted of an equilibration period (7 days), a first control period, a SARA period and a second control period (5 days each). During the SARA period, SARA was induced by infusing SARA1 or SARA2 buffer with reduced bicarbonate (20 mmol/L and 25 mmol/L) and phosphate (both 10 mmol/L) contents compared to a modified McDougall's buffer (bicarbonate 97.9 mmol/L, phosphates 20 mmol/L). Additionally, we compared three feeding strategies, which differed in the concentrate‐to‐roughage ratio (30:70, 70:30, changing ratio: 30% concentrate in control periods and 70% concentrate in SARA period). During the SARA period, the pH decreased to a constant value below the SARA thresholds of pH 5.8 and 5.6, whereas lactate concentrations remained low. The total SCFA production rate declined 3 days after SARA induction, and the molar proportion of acetate decreased. The decrease in pH and SCFA production was more pronounced for SARA1 buffer. The high‐concentrate diet reduced the molar proportion of acetate and increased NH₃‐N concentrations. During the second control period, most parameters recovered. In conclusion, SARA conditions were successfully induced in the Rusitec. However, we observed a higher influence of buffer composition than of concentrate proportions on most biochemical parameters. Nearly all changes were reversible. This model can be applied to test acidosis prevention strategies prior to animal experiments.
    Keywords acetates ; animal nutrition ; animal physiology ; animal welfare ; bicarbonates ; dairy cattle ; feed concentrates ; fermentation ; lactic acid ; models ; pH ; phosphates
    Language English
    Dates of publication 2020-11
    Size p. 1678-1689.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note NAL-AP-2-clean ; JOURNAL ARTICLE
    ISSN 0931-2439
    DOI 10.1111/jpn.13412
    Database NAL-Catalogue (AGRICOLA)

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  10. Article: Long-Term Mootral Application Impacts Methane Production and the Microbial Community in the Rumen Simulation Technique System.

    Brede, Johanna / Peukert, Manuela / Egert, Björn / Breves, Gerhard / Brede, Melanie

    Frontiers in microbiology

    2021  Volume 12, Page(s) 691502

    Abstract: Methane emissions by ruminants contribute to global warming and result in a loss of dietary energy for the animals. One possibility of reducing methane emissions is by dietary strategies. In the present trial, we investigated the long-term effects of ... ...

    Abstract Methane emissions by ruminants contribute to global warming and result in a loss of dietary energy for the animals. One possibility of reducing methane emissions is by dietary strategies. In the present trial, we investigated the long-term effects of Mootral, a feed additive consisting of garlic powder (
    Language English
    Publishing date 2021-10-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2021.691502
    Database MEDical Literature Analysis and Retrieval System OnLINE

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