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  1. Book ; Online ; E-Book: The neurology of HIV infection

    Brew, Bruce James

    (Handbook of clinical neurology ; 152)

    2018  

    Author's details volume editor Bruce James Brew
    Series title Handbook of clinical neurology ; 152
    Collection
    Keywords HIV infections ; Neurology
    Subject code 616.979207
    Language English
    Size 1 Online-Ressource (xvi, 297 Seiten), Illustrationen
    Publisher Elsevier
    Publishing place Amsterdam
    Publishing country Netherlands
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019667685
    ISBN 978-0-444-63850-2 ; 9780444638496 ; 0-444-63850-4 ; 0444638490
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  2. Article ; Online: Is HIV Brain Disease Preventable?

    Brew, Bruce J

    Neurology(R) neuroimmunology & neuroinflammation

    2022  Volume 9, Issue 2

    MeSH term(s) Brain Diseases ; HIV Infections/diagnosis ; HIV Infections/epidemiology ; HIV Infections/prevention & control ; Humans
    Language English
    Publishing date 2022-02-09
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2767740-0
    ISSN 2332-7812 ; 2332-7812
    ISSN (online) 2332-7812
    ISSN 2332-7812
    DOI 10.1212/NXI.0000000000001145
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Plasma neurofilament light chain protein predicts greater brain-age gap, cognition, and cardiovascular risk in people with HIV.

    Vance, David E / Brew, Bruce James

    AIDS (London, England)

    2024  Volume 38, Issue 7, Page(s) 1081–1083

    MeSH term(s) Humans ; HIV Infections/complications ; Cardiovascular Diseases/blood ; Neurofilament Proteins/blood ; Male ; Middle Aged ; Female ; Adult ; Plasma/chemistry ; Cognition ; Brain ; Aged
    Chemical Substances neurofilament protein L ; Neurofilament Proteins
    Language English
    Publishing date 2024-05-01
    Publishing country England
    Document type Letter ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Journal Article
    ZDB-ID 639076-6
    ISSN 1473-5571 ; 0269-9370 ; 1350-2840
    ISSN (online) 1473-5571
    ISSN 0269-9370 ; 1350-2840
    DOI 10.1097/QAD.0000000000003880
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2228: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Antiretroviral therapy intensification for HIV-associated neurocognitive disorder?

    Brew, Bruce J / Clifford, David B

    AIDS (London, England)

    2023  Volume 37, Issue 13, Page(s) 2095–2096

    MeSH term(s) Humans ; HIV Infections/complications ; HIV Infections/drug therapy ; AIDS Dementia Complex/drug therapy ; Anti-HIV Agents/therapeutic use ; Neurocognitive Disorders/drug therapy ; Antiretroviral Therapy, Highly Active ; Neuropsychological Tests
    Chemical Substances Anti-HIV Agents
    Language English
    Publishing date 2023-09-28
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 639076-6
    ISSN 1473-5571 ; 0269-9370 ; 1350-2840
    ISSN (online) 1473-5571
    ISSN 0269-9370 ; 1350-2840
    DOI 10.1097/QAD.0000000000003694
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2228: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Is neurocognitive ageing accelerated in virally suppressed people with HIV and multimorbidity?

    Cysique, Lucette A / Brew, Bruce J

    Brain : a journal of neurology

    2023  Volume 146, Issue 3, Page(s) 801–802

    MeSH term(s) Humans ; Multimorbidity ; Aging ; HIV Infections/complications ; Comorbidity
    Language English
    Publishing date 2023-01-21
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 80072-7
    ISSN 1460-2156 ; 0006-8950
    ISSN (online) 1460-2156
    ISSN 0006-8950
    DOI 10.1093/brain/awad035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui II Zs.26: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Extracellular vesicle small noncoding RNAs: a window into pathogenesis and diagnosis.

    Hu, Guoku / Brew, Bruce J

    AIDS (London, England)

    2023  Volume 37, Issue 5, Page(s) 849–850

    MeSH term(s) Humans ; RNA, Small Untranslated/genetics ; HIV Infections ; MicroRNAs/genetics ; Extracellular Vesicles
    Chemical Substances RNA, Small Untranslated ; MicroRNAs
    Language English
    Publishing date 2023-03-02
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 639076-6
    ISSN 1473-5571 ; 0269-9370 ; 1350-2840
    ISSN (online) 1473-5571
    ISSN 0269-9370 ; 1350-2840
    DOI 10.1097/QAD.0000000000003517
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2228: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Book: HIV neurology

    Brew, Bruce James

    (Contemporary neurology series ; 61)

    2001  

    Author's details Bruce James Brew
    Series title Contemporary neurology series ; 61
    Collection
    Keywords HIV Infections / complications ; Aids-Related Oppurtunistic Infection ; Brain Diseases / etiology ; Muscular Diseases / etiology ; Neurologic Manifestations ; Peripheral Nervous System Diseases / etiology ; Spinal Cord Diseases / etiology
    Language English
    Size XVI, 252 S. : Ill., graph. Darst.
    Publisher Oxford Univ. Press
    Publishing place Oxford
    Publishing country United States
    Document type Book
    HBZ-ID HT013126208
    ISBN 0-19-513363-3 ; 978-0-19-513363-9
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2001 A 4758 order for loan Magazin

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  8. Article ; Online: Reversible large-scale network disruption correlates with neurocognitive improvement in HIV-associated minor neurocognitive disorder with combined anti-retroviral therapy intensification: a prospective longitudinal resting-state functional magnetic resonance imaging study.

    Chaganti, Joga / Gates, Thomas M / Brew, Bruce J

    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    2023  Volume 44, Issue 9, Page(s) 3261–3269

    Abstract: Objective: HIV-associated neurocognitive disorder (HAND) affects multiple cognitive domains and currently, the neuropsychological testing is the gold standard to identify these deficits. The aim of this longitudinal 12-month pilot study is to determine ... ...

    Abstract Objective: HIV-associated neurocognitive disorder (HAND) affects multiple cognitive domains and currently, the neuropsychological testing is the gold standard to identify these deficits. The aim of this longitudinal 12-month pilot study is to determine the effect of intensified combination antiretroviral therapy (cART) on rs-fMRI in virally suppressed (both in CSF and blood) patients with active HAND (those who have progressive neurocognitive impairment) and correlated with neurocognitive function tests.
    Methods: In this pilot study, we have evaluated sixteen patients with active HAND with viral suppression in both blood and CSF to study the effect of cART on functional connectivity. Participants underwent rs-fMRI at the baseline (time point-1 (TP-1) and 12-month visits (time point-2 (TP-2)). Connectivity in the five major networks was measured at TP-1 and TP-2 using the seed-based approach. All the participants underwent a five-domain neuropsychological battery at TP-1 and TP-2. Neurocognitive scores (NC) as well as blood and CSF markers were correlated with functional connectivity (FC).
    Results: There was a significant increase in the FC between the two time points within the executive, salience, default mode, dorsal attention, and visual networks at voxel level threshold of p < 0.001 and cluster level threshold of p < 0.05 and corrected for false detection rate (FDR). The neurocognitive scores were positively correlated with all the networks at similar cluster and voxel level thresholds.
    Conclusions: These results indicate that rs-fMRI can be potentially used as one of the biomarkers for treatment efficacy in HAND.
    MeSH term(s) Humans ; HIV ; Prospective Studies ; Pilot Projects ; HIV Infections/complications ; HIV Infections/diagnostic imaging ; HIV Infections/drug therapy ; Neurocognitive Disorders/complications ; Neurocognitive Disorders/pathology ; Magnetic Resonance Imaging ; Brain ; Brain Mapping
    Language English
    Publishing date 2023-04-13
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2016546-8
    ISSN 1590-3478 ; 1590-1874
    ISSN (online) 1590-3478
    ISSN 1590-1874
    DOI 10.1007/s10072-023-06783-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1877: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  9. Article: Preface.

    Brew, Bruce J

    Handbook of clinical neurology

    2018  Volume 152, Page(s) xi

    MeSH term(s) Guidelines as Topic ; HIV/pathogenicity ; Humans ; Knowledge
    Language English
    Publishing date 2018-03-06
    Publishing country Netherlands
    Document type Editorial
    ISSN 0072-9752
    ISSN 0072-9752
    DOI 10.1016/B978-0-444-63849-6.09988-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Introduction to HIV infection and HIV neurology.

    Brew, Bruce James

    Handbook of clinical neurology

    2018  Volume 152, Page(s) 1–2

    Abstract: In this introductory chapter the impact of combination antiretriviral therapy is discussed. Three different "types" of HIV infection are described according to medication adherence and efficacy. Next, general principles of HIV related neurologic ... ...

    Abstract In this introductory chapter the impact of combination antiretriviral therapy is discussed. Three different "types" of HIV infection are described according to medication adherence and efficacy. Next, general principles of HIV related neurologic complications are defined. Last, a clinical approach to the HIV infected patient with a neurologic complication is then detailed.
    MeSH term(s) Antiretroviral Therapy, Highly Active/methods ; Antiretroviral Therapy, Highly Active/trends ; HIV Infections/diagnosis ; HIV Infections/epidemiology ; HIV Infections/therapy ; Humans ; Nervous System Diseases/diagnosis ; Nervous System Diseases/epidemiology ; Nervous System Diseases/therapy
    Language English
    Publishing date 2018-05-07
    Publishing country Netherlands
    Document type Introductory Journal Article
    ISSN 0072-9752
    ISSN 0072-9752
    DOI 10.1016/B978-0-444-63849-6.00001-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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