LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 212

Search options

  1. Article ; Online: Obesity and GLP-1 RAs.

    Bright, Tamis

    Journal of investigative medicine : the official publication of the American Federation for Clinical Research

    2022  Volume 70, Issue 1, Page(s) 1–2

    MeSH term(s) Anti-Obesity Agents/therapeutic use ; Diabetes Mellitus, Type 2/drug therapy ; Glucagon-Like Peptide 1 ; Glucagon-Like Peptide-1 Receptor/therapeutic use ; Humans ; Hypoglycemic Agents/therapeutic use ; Obesity/therapy
    Chemical Substances Anti-Obesity Agents ; Glucagon-Like Peptide-1 Receptor ; Hypoglycemic Agents ; Glucagon-Like Peptide 1 (89750-14-1)
    Language English
    Publishing date 2022-03-24
    Publishing country England
    Document type Editorial
    ZDB-ID 1217870-6
    ISSN 1708-8267 ; 0009-9279 ; 1081-5589
    ISSN (online) 1708-8267
    ISSN 0009-9279 ; 1081-5589
    DOI 10.1136/jim-2021-002268
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Measuring the quality of surgical care in Australia.

    Watson, David I / Bright, Tim

    The Medical journal of Australia

    2022  Volume 217, Issue 6, Page(s) 301–302

    MeSH term(s) Australia ; Humans ; Quality of Health Care
    Language English
    Publishing date 2022-08-16
    Publishing country Australia
    Document type Editorial ; Comment
    ZDB-ID 186082-3
    ISSN 1326-5377 ; 0025-729X
    ISSN (online) 1326-5377
    ISSN 0025-729X
    DOI 10.5694/mja2.51684
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: COVID-19 vaccine acceptance and its determinants in the Bono Region of Ghana.

    Forkuo, Bright T / Osarfo, Joseph / Ampofo, Gifty D

    Ghana medical journal

    2023  Volume 56, Issue 4, Page(s) 239–245

    Abstract: Objective: The study assessed willingness to accept the COVID-19 vaccine among out-patient department (OPD) attendants in the Bono Region in Ghana.: Design: This was an analytical cross-sectional study.: Setting: The study was conducted at the ... ...

    Abstract Objective: The study assessed willingness to accept the COVID-19 vaccine among out-patient department (OPD) attendants in the Bono Region in Ghana.
    Design: This was an analytical cross-sectional study.
    Setting: The study was conducted at the Wenchi Methodist Hospital (WMH) OPD, Bono Region, Ghana. The region had not yet been earmarked for vaccination at the time of the study.
    Participants: Three hundred and twenty-five (325) participants aged ≥18 years, accessing care at the OPD of WMH and willing to give informed consent, were interviewed.
    Main outcome measures: The proportion of participants willing to accept the COVID-19 vaccine and its determinants.
    Results: Of 325 participants interviewed, 32 (9.8%) had been vaccinated already. 82.6% (242/293) indicated COVID-19 vaccine acceptance among the unvaccinated
    Conclusions: Adequate knowledge of COVID-19 and the vaccine may drive vaccine acceptance in the study area and possibly other areas in Ghana. Campaign messages aimed at increasing COVID-19 vaccine coverage must emphasise its safety, likely side effects and management in order to help rid the population of misconceptions.
    Funding: None indicated.
    MeSH term(s) Humans ; Adolescent ; Adult ; COVID-19 Vaccines ; COVID-19/epidemiology ; COVID-19/prevention & control ; Ghana ; Cross-Sectional Studies ; Drug-Related Side Effects and Adverse Reactions
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2023-08-10
    Publishing country Ghana
    Document type Journal Article
    ZDB-ID 2259233-7
    ISSN 2616-163X ; 2616-163X
    ISSN (online) 2616-163X
    ISSN 2616-163X
    DOI 10.4314/gmj.v56i4.2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: ASO Author Reflections: Preventable Mortality Following Esophago-Gastric Cancer Resection.

    Liu, David S / Bright, Tim / Watson, David I

    Annals of surgical oncology

    2023  Volume 30, Issue 8, Page(s) 4962–4963

    MeSH term(s) Humans ; Stomach Neoplasms/mortality ; Stomach Neoplasms/surgery ; Esophageal Neoplasms/mortality ; Esophageal Neoplasms/surgery
    Language English
    Publishing date 2023-05-08
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-023-13585-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: The value of assessing post-operative mortality after oesophagectomy.

    Bright, Tim

    ANZ journal of surgery

    2016  Volume 86, Issue 3, Page(s) 114–115

    MeSH term(s) Esophageal Neoplasms/surgery ; Esophagectomy ; Humans ; Postoperative Period
    Language English
    Publishing date 2016-03
    Publishing country Australia
    Document type Comment ; Editorial
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1111/ans.13407
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Endoscopic repair of esophagogastric fistula.

    Duffield, J A / Bright, T

    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    2016  Volume 29, Issue 6, Page(s) 697–698

    MeSH term(s) Esophageal Fistula/diagnostic imaging ; Esophageal Fistula/surgery ; Esophagoscopy/methods ; Female ; Fluoroscopy ; Fundoplication ; Gastric Fistula/diagnostic imaging ; Gastric Fistula/surgery ; Gastroscopy/methods ; Humans ; Laparoscopy ; Postoperative Complications/surgery ; Young Adult
    Language English
    Publishing date 2016-08
    Publishing country United States
    Document type Case Reports
    ZDB-ID 639470-x
    ISSN 1442-2050 ; 1120-8694
    ISSN (online) 1442-2050
    ISSN 1120-8694
    DOI 10.1111/dote.12198
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Evaluating the inclusion of tympanometry in population-based surveys of hearing loss.

    Bright, T / Youngs, R / Faal, Y / Hydara, A / Yip, J L Y / Mactaggart, I / Polack, S

    The Journal of laryngology and otology

    2022  Volume 136, Issue 9, Page(s) 839–847

    Abstract: Objective: This study aimed to determine the implications of including tympanometry in the Rapid Assessment of Hearing Loss survey protocol. A comparative study design was employed, with findings from otoscopy compared with the results of tympanometry.!# ...

    Abstract Objective: This study aimed to determine the implications of including tympanometry in the Rapid Assessment of Hearing Loss survey protocol. A comparative study design was employed, with findings from otoscopy compared with the results of tympanometry.
    Method: A population-based survey of the prevalence and causes of hearing loss among adults aged over 35 years in The Gambia was conducted. Clinical assessments included air conduction audiometry, otoscopy and clinical history. Otoscopy outcome was recorded and for those with hearing loss, a probable cause was assigned. Following otoscopy, tympanometry was completed. Otoscopy outcome was not changed as a result of tympanometry. Clinician assigned cause was compared to the results of tympanometry. The proportion of causes potentially misclassified by excluding tympanometry was determined.
    Results: Among people with hearing loss, including tympanometry led to a higher proportion diagnosed with middle-ear conditions.
    Conclusion: The value of adding tympanometry to population-based survey protocols is a higher estimated proportion of hearing loss being attributed to middle-ear disease rather than sensorineural causes. This can inform service needs as more people will be classified as needing medical or surgical services, and a slightly lower number will need rehabilitative services, such as hearing assistive devices. It is highly recommended that tympanometry is included in the protocol.
    MeSH term(s) Acoustic Impedance Tests/methods ; Adult ; Audiometry ; Deafness ; Hearing Loss/diagnosis ; Hearing Loss/epidemiology ; Humans ; Otoscopy/methods ; Prevalence
    Language English
    Publishing date 2022-05-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 218299-3
    ISSN 1748-5460 ; 0022-2151
    ISSN (online) 1748-5460
    ISSN 0022-2151
    DOI 10.1017/S0022215122001190
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Planned oesophagectomy after chemoradiotherapy versus salvage oesophagectomy following definitive chemoradiotherapy: a systematic review and meta-analysis.

    Petric, Josipa / Handshin, Samuel / Bright, Tim / Watson, David I

    ANZ journal of surgery

    2022  Volume 93, Issue 4, Page(s) 829–839

    Abstract: Background: Oesophageal cancer is the eighth most common cancer and sixth leading cause of cancer-related mortality worldwide. Salvage oesophagectomies are associated with an increased risk of mortality, although recent data suggests that long-term ... ...

    Abstract Background: Oesophageal cancer is the eighth most common cancer and sixth leading cause of cancer-related mortality worldwide. Salvage oesophagectomies are associated with an increased risk of mortality, although recent data suggests that long-term survival rates following salvage oesophagectomy are similar to planned oesophagectomy. The aim was therefore to meta-analyse outcomes for patients undergoing salvage versus planned oesophagectomies to assess the differences in short-term mortality and long-term survival.
    Methods: A systematic review of Medline, Scopus, Web of Science and PubMed was performed to identify relevant studies. Data were extracted and compared by meta-analysis, using odds ratio and mean differences with 95% confidence intervals.
    Results: Nineteen studies meeting inclusion criteria were included in the meta-analysis, which compared patients in the planned oesophagectomy group (n = 23 555) to patients in the salvage oesophagectomy group (n = 2227). There were significant differences between the groups in terms of rates of postoperative mortality (5.7% salvage oesophagectomy versus 3.1% planned oesophagectomy, P = 0.0004), anastomotic leak (20.6% salvage oesophagectomy versus 14.5% planned oesophagectomy, P < 0.00001), pulmonary complications (37.1% salvage oesophagectomy versus 24.2% planned oesophagectomy, P < 0.0001) and R0 margin (87.6% salvage oesophagectomy versus 91.3% planned oesophagectomy, P < 0.0001). There was no statistical difference between long-term survival rates at 5 years with 39.2% for salvage and 42.6% for planned oesophagectomy (P = 0.28).
    Conclusions: Salvage oesophagectomies do offer a meaningful chance of long-term survival (at 5 years) for select patients with oesophageal cancer, but the elevated risk of post-operative complications and mortality following salvage oesophagectomy should be recognized.
    MeSH term(s) Humans ; Esophagectomy/adverse effects ; Chemoradiotherapy ; Esophageal Neoplasms/surgery ; Anastomotic Leak/etiology ; Postoperative Complications/etiology
    Language English
    Publishing date 2022-12-29
    Publishing country Australia
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1111/ans.18225
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Quantifying Perioperative Risks for Antireflux and Hiatus Hernia Surgery: A Multicenter Cohort Study of 4301 Patients.

    Liu, David S / Wong, Darren J / Goh, Su Kah / Fayed, Aly / Stevens, Sean / Aly, Ahmad / Bright, Tim / Weinberg, Laurence / Watson, David I

    Annals of surgery

    2024  Volume 279, Issue 5, Page(s) 796–807

    Abstract: Objective: Using a comprehensive Australian cohort, we quantified the incidence and determined the independent predictors of intraoperative and postoperative complications associated with antireflux and hiatus hernia surgeries. In addition, we performed ...

    Abstract Objective: Using a comprehensive Australian cohort, we quantified the incidence and determined the independent predictors of intraoperative and postoperative complications associated with antireflux and hiatus hernia surgeries. In addition, we performed an in-depth analysis to understand the complication profiles associated with each independent risk factor.
    Background: Predicting perioperative risks for fundoplication and hiatus hernia repair will inform treatment decision-making, hospital resource allocation, and benchmarking. However, available risk calculators do not account for hernia anatomy or technical aspects of surgery in estimating perioperative risk.
    Methods: Retrospective analysis of all elective antireflux and hiatus hernia surgeries in 36 Australian hospitals over 10 years. Hierarchical multivariate logistic regression analyses were performed to determine the independent predictors of intraoperative and postoperative complications accounting for patient, surgical, anatomic, and perioperative factors.
    Results: A total of 4301 surgeries were analyzed. Of these, 1569 (36.5%) were large/giant hernias and 292 (6.8%) were revisional procedures. The incidence rates of intraoperative and postoperative complications were 12.6% and 13.3%, respectively. The Charlson Comorbidity Index, hernia size, revisional surgery, and baseline anticoagulant usage independently predicted both intraoperative and postoperative complications. These risk factors were associated with their own complication profiles. Finally, using risk matrices, we visualized the cumulative impact of these 4 risk factors on the development of intraoperative, overall postoperative, and major postoperative complications.
    Conclusions: This study has improved our understanding of perioperative morbidity associated with antireflux and hiatus hernia surgery. Our findings group patients along a spectrum of perioperative risks that inform care at an individual and institutional level.
    MeSH term(s) Humans ; Hernia, Hiatal/surgery ; Hernia, Hiatal/etiology ; Retrospective Studies ; Australia/epidemiology ; Fundoplication/adverse effects ; Fundoplication/methods ; Herniorrhaphy/adverse effects ; Herniorrhaphy/methods ; Postoperative Complications/etiology ; Laparoscopy/adverse effects ; Laparoscopy/methods
    Language English
    Publishing date 2024-02-06
    Publishing country United States
    Document type Multicenter Study ; Journal Article
    ZDB-ID 340-2
    ISSN 1528-1140 ; 0003-4932
    ISSN (online) 1528-1140
    ISSN 0003-4932
    DOI 10.1097/SLA.0000000000006223
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Quality of life following repair of large hiatal hernia is not influenced by the use of mesh-Longer-term follow-up from a randomized trial.

    Amprayil, Mathew A / Irvine, Tanya / Thompson, Sarah K / Bright, Tim / Aly, Ahmad / Devitt, Peter G / Jamieson, Glyn G / Watson, David I

    World journal of surgery

    2024  

    Abstract: Introduction: The use of prosthetic mesh in laparoscopic repair of large hiatus hernias remains controversial. Clinical and quality of life outcomes from a randomized controlled trial of mesh versus suture repair previously showed few differences at ... ...

    Abstract Introduction: The use of prosthetic mesh in laparoscopic repair of large hiatus hernias remains controversial. Clinical and quality of life outcomes from a randomized controlled trial of mesh versus suture repair previously showed few differences at early follow-up. This study evaluated longer-term quality of life outcomes from that trial.
    Methods: A prospective, multicentre, double blind randomized controlled trial assessed three methods of repair for large hiatus hernias: sutures-only versus absorbable mesh versus non-absorbable mesh. Quality of life was assessed using the Short-Form 36 (SF-36) questionnaire which was completed preoperatively and then at 3, 6, 12 months following surgery and annually thereafter. SF-36 outcomes were compared across the three repair techniques at longer-term follow-up (3-6 years), and to earlier baseline and 12-month outcomes.
    Results: 126 patients were randomized; 43-suture-only, 41-absorbable mesh and 42-non-absorbable mesh. Questionnaires were completed by 118 patients preoperatively, 115 at 12 months and 98 at longer-term follow-up (median 5 years). There were no significant differences between the repair techniques for the subscale and composite scores at longer-term follow-up. The mental component score improved significantly after surgery and was sustained across follow-up for all techniques. The physical component score also improved significantly but was lower at longer-term follow-up compared to the 12-month follow up in both mesh groups.
    Conclusion: Surgical repair of large hiatus hernias provides sustained long-term improvement in quality of life. The addition of mesh does not improve quality of life.
    Trial registration: This trial is registered with the Australia and New Zealand Clinical Trials Registry ACTRN12605000725662.
    Language English
    Publishing date 2024-04-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 224043-9
    ISSN 1432-2323 ; 0364-2313
    ISSN (online) 1432-2323
    ISSN 0364-2313
    DOI 10.1002/wjs.12185
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top