Article ; Online: Health related quality of life in Mexican women with systemic lupus erythematosus: a descriptive study using SF-36 and LupusQoL(C).
2012 Volume 21, Issue 11, Page(s) 1219–1224
Abstract: The LupusQoL© questionnaire is a disease-specific health related quality of life (HRQOL) instrument for adults with systemic lupus erythematosus (SLE). The Short Form-36 (SF-36) is a generic instrument that captures the physical, psychological, and ... ...
| Abstract | The LupusQoL© questionnaire is a disease-specific health related quality of life (HRQOL) instrument for adults with systemic lupus erythematosus (SLE). The Short Form-36 (SF-36) is a generic instrument that captures the physical, psychological, and social impact. We conducted a descriptive study of women aged ≥ 18 years attending our Lupus Clinic. HRQOL was assessed by applying the LupusQoL© and SF-36. Lupus activity was measured using the Mexican Systemic Lupus Erythematosus Disease Activity Index (Mex-SLEDAI) and chronic damage using the Systemic Lupus Collaborative Clinics Damage Index (SDI). Data were analyzed using descriptive statistics, the chi-square test and Pearson's product moment correlation coefficient. A total of 127 patients were included with a mean age of 40.5 ± 12.6 years. The mean disease duration was 8.2 ± 5.6 years, the mean disease activity score was 2.4 ± 3.0, and the mean SDI score 0.77 ± 1.06. The mean SF-36 score was 58.1 ± 21.1 and the mean LupusQoL© score was 69 ± 22.7. The correlation between global scores of the SF-36 and LupusQoL© was rho = 0.73 (p < 0.001). The correlation between lupus disease activity and the SF-36 and the LupusQoL© was -0.26 (p = 0.003) and -0.25 (p = 0.004), respectively. The correlation between the SDI and the SF-36 and the LupusQoL© was -0.28 (p = 0.001) and -0.38 (p < 0.0001), respectively. In conclusions: both LupusQoL© and SF-36 were useful instruments in assessing HRQOL in Mexican lupus female patients. The usefulness of the LupusQoL© should be evaluated in lupus patients with moderate to severe disease activity. |
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| MeSH term(s) | Adult ; Chi-Square Distribution ; Cross-Sectional Studies ; Data Interpretation, Statistical ; Female ; Humans ; Lupus Erythematosus, Systemic/physiopathology ; Middle Aged ; Quality of Life ; Severity of Illness Index ; Surveys and Questionnaires |
| Language | English |
| Publishing date | 2012-10 |
| Publishing country | England |
| Document type | Comparative Study ; Journal Article |
| ZDB-ID | 1154407-7 |
| ISSN | 1477-0962 ; 0961-2033 |
| ISSN (online) | 1477-0962 |
| ISSN | 0961-2033 |
| DOI | 10.1177/0961203312456749 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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