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  1. Article: Genistein supplementation has no effects on vitamin D levels in healthy Spanish postmenopausal women.

    Pérez-Alonso, María / Calero-Paniagua, Ismael / Usategui-Martin, Ricardo / Briongos, Laisa-Socorro / Ruiz-Mambrilla, Marta / Olmos, José-Manuel / González-Sagrado, Manuel / De Luis, Daniel / Dueñas-Laita, Antonio / Pérez-Castrillón, José-Luis

    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition

    2023  

    Language English
    Publishing date 2023-03-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 120692-8
    ISSN 0300-9831
    ISSN 0300-9831
    DOI 10.1024/0300-9831/a000781
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.210: Show issues Location:
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  2. Article: Association Between Bat Vitamin D Receptor 3' Haplotypes and Vitamin D Levels at Baseline and a Lower Response After Increased Vitamin D Supplementation and Exposure to Sunlight.

    Pérez-Alonso, María / Briongos, Laisa-Socorro / Ruiz-Mambrilla, Marta / Velasco, Eladio A / Olmos, José M / de Luis, Daniel / Dueñas-Laita, Antonio / Pérez-Castrillón, José-Luis

    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition

    2019  Volume 90, Issue 3-4, Page(s) 290–294

    MeSH term(s) Animals ; Chiroptera ; Cholecalciferol/chemistry ; Cholecalciferol/metabolism ; Dietary Supplements ; Female ; Genotype ; Haplotypes/genetics ; Humans ; Prospective Studies ; Receptors, Calcitriol ; Sunlight ; Vitamin D/chemistry ; Vitamin D/metabolism
    Chemical Substances Receptors, Calcitriol ; Vitamin D (1406-16-2) ; Cholecalciferol (1C6V77QF41)
    Language English
    Publishing date 2019-02-21
    Publishing country Switzerland
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 120692-8
    ISSN 0300-9831
    ISSN 0300-9831
    DOI 10.1024/0300-9831/a000534
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.210: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: The Effect of Genistein Supplementation on Vitamin D Levels and Bone Turnover Markers during the Summer in Healthy Postmenopausal Women: Role of Genotypes of Isoflavone Metabolism.

    Pérez-Alonso, María / Briongos, Laisa-Socorro / Ruiz-Mambrilla, Marta / Velasco, Eladio A / Linares, Lidia / Cuellar, Luis / Olmos, José-Manuel / De Luis, Daniel / Dueñas-Laita, Antonio / Pérez-Castrillón, José-Luis

    Journal of nutrigenetics and nutrigenomics

    2017  Volume 10, Issue 5-6, Page(s) 139–145

    Abstract: Aims: The objective of this study was to determine whether vitamin D and genistein supplementation had an additive beneficial effect on levels of vitamin D and bone markers and whether this effect was mediated by genes regulating isoflavone metabolism.!# ...

    Abstract Aims: The objective of this study was to determine whether vitamin D and genistein supplementation had an additive beneficial effect on levels of vitamin D and bone markers and whether this effect was mediated by genes regulating isoflavone metabolism.
    Materials and methods: We carried out a prospective study in postmenopausal women randomized to calcium and vitamin D supplementation or calcium, vitamin D, and genistein supplementation. Vitamin D, parathyroid hormone (PTH), cross-linked C-telopeptide (CTX), and procollagen 1 N-terminal (P1NP) were determined by electrochemiluminescence. Three SNPs - rs2231142 (ABCG2), rs358231 (cytosolic β-glucosidase [CBG]), and rs2273697 (ABCC2) - were determined.
    Results: We included 102 women. The effects on bone remodeling were similar: rises in vitamin D were significantly associated with reductions in PTH, CTX, and P1NP. Pharmacogenomic analysis of the genotypes showed that, in AT heterozygotes of the CBG1368T>A polymorphism, CTX and P1NP were not reduced.
    Conclusion: Genistein added to calcium and vitamin D supplementation had no additional effect. The supplementation of individual AT heterozygotes of the CBG1368T>A polymorphism had no effect on markers of bone remodeling.
    MeSH term(s) ATP Binding Cassette Transporter, Subfamily G, Member 2/genetics ; Biomarkers/blood ; Bone Remodeling/drug effects ; Calcium, Dietary/administration & dosage ; Collagen Type I/blood ; Dietary Supplements ; Female ; Genistein/administration & dosage ; Genistein/metabolism ; Genotype ; Healthy Volunteers ; Humans ; Isoflavones/metabolism ; Middle Aged ; Multidrug Resistance-Associated Proteins/genetics ; Neoplasm Proteins/genetics ; Nutrigenomics ; Parathyroid Hormone/blood ; Peptide Fragments/blood ; Peptides/blood ; Polymorphism, Single Nucleotide ; Postmenopause ; Procollagen/blood ; Prospective Studies ; Seasons ; Vitamin D/administration & dosage ; Vitamin D/blood ; beta-Glucosidase/genetics
    Chemical Substances ABCG2 protein, human ; ATP Binding Cassette Transporter, Subfamily G, Member 2 ; Biomarkers ; Calcium, Dietary ; Collagen Type I ; Isoflavones ; Multidrug Resistance-Associated Proteins ; Neoplasm Proteins ; PTH protein, human ; Parathyroid Hormone ; Peptide Fragments ; Peptides ; Procollagen ; collagen type I trimeric cross-linked peptide ; procollagen Type I N-terminal peptide ; Vitamin D (1406-16-2) ; multidrug resistance-associated protein 2 (4AF605U6JN) ; Genistein (DH2M523P0H) ; GBA3 protein, human (EC 3.2.1.21) ; beta-Glucosidase (EC 3.2.1.21)
    Language English
    Publishing date 2017-11-18
    Publishing country Switzerland
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2253668-1
    ISSN 1661-6758 ; 1661-6499
    ISSN (online) 1661-6758
    ISSN 1661-6499
    DOI 10.1159/000484480
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 7783: Show issues

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  4. Article: The Effect of Genistein Supplementation on Vitamin D Levels and Bone Turnover Markers during the Summer in Healthy Postmenopausal Women: Role of Genotypes of Isoflavone Metabolism

    Pérez-Alonso, María / Briongos, Laisa-Socorro / Ruiz-Mambrilla, Marta / Velasco, Eladio A. / Linares, Lidia / Cuellar, Luis / Olmos, José-Manuel / De Luis, Daniel / Dueñas-Laita, Antonio / Pérez-Castrillón, José-Luis

    Journal of Nutrigenetics and Nutrigenomics

    2017  Volume 10, Issue 5-6, Page(s) 139–145

    Abstract: Aims: The objective of this study was to determine whether vitamin D and genistein supplementation had an additive beneficial effect on levels of vitamin D and bone markers and whether this effect was mediated by genes regulating isoflavone metabolism. ... ...

    Institution University of Valladolid Department of Internal Medicine, University Hospital Río Hortega Centro Médico de Rehabilitación y Lenguaje Institute of Biology and Molecular Genetics, University of Valladolid, CSIC-UVA, and Department of Endocrinology, University Hospital Río Hortega, Valladolid Department of Internal Medicine, University Hospital Marques de Valdecilla, University of Cantabria, Santander Department of Endocrinology, University Hospital Valladolid, University of Valladolid, and Department of Clinical Pharmacology, University Hospital Río Hortega, University of Valladolid, Valladolid, Spain
    Abstract Aims: The objective of this study was to determine whether vitamin D and genistein supplementation had an additive beneficial effect on levels of vitamin D and bone markers and whether this effect was mediated by genes regulating isoflavone metabolism. Materials and Methods: We carried out a prospective study in postmenopausal women randomized to calcium and vitamin D supplementation or calcium, vitamin D, and genistein supplementation. Vitamin D, parathyroid hormone (PTH), cross-linked C-telopeptide (CTX), and procollagen 1 N-terminal (P1NP) were determined by electrochemiluminescence. Three SNPs - rs2231142 (ABCG2), rs358231 (cytosolic β-glucosidase [CBG]), and rs2273697 (ABCC2) - were determined. Results: We included 102 women. The effects on bone remodeling were similar: rises in vitamin D were significantly associated with reductions in PTH, CTX, and P1NP. Pharmacogenomic analysis of the genotypes showed that, in AT heterozygotes of the CBG1368T>A polymorphism, CTX and P1NP were not reduced. Conclusion: Genistein added to calcium and vitamin D supplementation had no additional effect. The supplementation of individual AT heterozygotes of the CBG1368T>A polymorphism had no effect on markers of bone remodeling.
    Keywords Vitamin D ; Cross-linked C-telopeptide ; Parathyroid hormone ; Procollagen 1 N-terminal ; Genistein ; Polymorphism
    Language English
    Publishing date 2017-11-18
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    Note Original Paper
    ZDB-ID 2253668-1
    ISSN 1661-6758 ; 1661-6499
    ISSN (online) 1661-6758
    ISSN 1661-6499
    DOI 10.1159/000484480
    Database Karger publisher's database

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    In stock of ZB MED Bonn / Germany

    Z 7783: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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