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Article ; Online: Collective antiretroviral protection: new dimensions of community HIV prevention practices at the intersection of U=U and PrEP.

Brisson, Julien B / Grace, Daniel / Perez-Brumer, Amaya G

The lancet. HIV

2024  Volume 11, Issue 5, Page(s) e341–e344

Abstract: Collective antiretroviral protection is an evolving sexual health strategy in HIV prevention, used in particular by gay, bisexual, and other men who have sex with men. The strategy involves HIV-negative individuals who engage in condomless sexual ... ...

Abstract Collective antiretroviral protection is an evolving sexual health strategy in HIV prevention, used in particular by gay, bisexual, and other men who have sex with men. The strategy involves HIV-negative individuals who engage in condomless sexual activities but, instead of using pre-exposure prophylaxis (PrEP) themselves, choose partners who either have undetectable viral loads or are on PrEP. This biomedical-sorting practice, rooted in the scientific principles of undetectable equals untransmittable (U=U) and PrEP, relies on an indirect protection strategy. Collective antiretroviral protection allows for HIV-negative individuals not on PrEP to benefit from their partner's antiretroviral use, without directly consuming antiretrovirals themselves for HIV prevention, during condomless sex. Empirical research is needed to evaluate the public health implications of this emerging sexual health approach. Research and public health initiatives should adopt a non-stigmatising approach to individuals engaging in collective antiretroviral protection and look beyond individual behaviour to understand the broader community-level effects of this innovative HIV prevention strategy.
MeSH term(s) Humans ; HIV Infections/prevention & control ; Pre-Exposure Prophylaxis ; Male ; Homosexuality, Male ; Anti-HIV Agents/therapeutic use ; Anti-HIV Agents/administration & dosage ; Sexual and Gender Minorities ; Viral Load ; Sexual Partners ; Sexual Behavior
Chemical Substances Anti-HIV Agents
Language English
Publishing date 2024-03-18
Publishing country Netherlands
Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
ISSN 2352-3018
ISSN (online) 2352-3018
DOI 10.1016/S2352-3018(24)00034-1
Database MEDical Literature Analysis and Retrieval System OnLINE

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