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  1. Article ; Online: Seeking help for mental health during the COVID-19 pandemic: A longitudinal analysis of adults' experiences with digital technologies and services.

    Parsons, Christine E / Purves, Kirstin L / Davies, Molly R / Mundy, Jessica / Bristow, Shannon / Eley, Thalia C / Breen, Gerome / Hirsch, Colette R / Young, Katherine S

    PLOS digital health

    2023  Volume 2, Issue 12, Page(s) e0000402

    Abstract: The COVID-19 pandemic brought about dramatic changes in how patients access healthcare from its outset. Lockdown restrictions and remote working led to a proliferation of digital technologies and services, which also impacted mental health provisions. ... ...

    Abstract The COVID-19 pandemic brought about dramatic changes in how patients access healthcare from its outset. Lockdown restrictions and remote working led to a proliferation of digital technologies and services, which also impacted mental health provisions. Against the backdrop of new and changing support services, along with an unprecedented emphasis on mental health, relatively little is known about how adults sought out and received support for their mental health during this period. With a sample of 27,574 adults assessed longitudinally online over 12 months of the pandemic in the UK, we analysed reports of help-seeking for mental health, as well as sources of treatment or support and the perceived helpfulness of treatments received. We observed that the proportions of participants who reported seeking help remained relatively consistent throughout the 12-month period (ranging from 12.6% to 17.0%). Online talking therapies were among the most frequently sought sources (15.3%), whereas online self-guided treatments were among the least frequently sought sources (5%). Telephone lines, both NHS and non-governmental, had marked treatment 'gaps'. These treatment gaps, where individuals sought treatment but did not receive it, were especially evident for men and older adults. Our findings underscore online talking therapies as being a widely-sought and helpful source of mental health support. This is important given the current global need for accessible treatment options.
    Language English
    Publishing date 2023-12-06
    Publishing country United States
    Document type Journal Article
    ISSN 2767-3170
    ISSN (online) 2767-3170
    DOI 10.1371/journal.pdig.0000402
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid-twenties.

    Lockhart, Celestine / Bright, Joanna / Ahmadzadeh, Yasmin / Breen, Gerome / Bristow, Shannon / Boyd, Andy / Downs, Johnny / Hotopf, Matthew / Palaiologou, Elisavet / Rimfeld, Kaili / Maxwell, Jessye / Malanchini, Margherita / McAdams, Tom A / McMillan, Andrew / Plomin, Robert / Eley, Thalia C

    JCPP advances

    2023  Volume 3, Issue 2, Page(s) e12154

    Abstract: The Twins Early Development Study (TEDS) is a longitudinal study following a cohort of twins born 1994-1996 in England and Wales. Of the 13,759 families who originally consented to take part, over 10,000 families remain enrolled in the study. The current ...

    Abstract The Twins Early Development Study (TEDS) is a longitudinal study following a cohort of twins born 1994-1996 in England and Wales. Of the 13,759 families who originally consented to take part, over 10,000 families remain enrolled in the study. The current focus of TEDS is on mental health in the mid-twenties. Making use of over 25 years of genetically sensitive data, TEDS is uniquely placed to explore the longitudinal genetic and environmental influences on common mental health disorders in early adulthood. This paper outlines recent data collection efforts supporting this work, including a cohort-wide mental health assessment at age 26 and a multi-phase Covid-19 study. It will also provide an update on data linkage efforts and the Children of TEDS (CoTEDS) project.
    Language English
    Publishing date 2023-03-30
    Publishing country United States
    Document type Journal Article
    ISSN 2692-9384
    ISSN (online) 2692-9384
    DOI 10.1002/jcv2.12154
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  3. Article ; Online: Different trajectories of depression, anxiety and anhedonia symptoms in the first 12 months of the COVID-19 pandemic in a UK longitudinal sample.

    Parsons, Christine E / Purves, Kirstin L / Skelton, Megan / Peel, Alicia J / Davies, Molly R / Rijsdijk, Fruhling / Bristow, Shannon / Eley, Thalia C / Breen, Gerome / Hirsch, Colette R / Young, Katherine S

    Psychological medicine

    2022  , Page(s) 1–11

    Abstract: Background: While studies from the start of the COVID-19 pandemic have described initial negative effects on mental health and exacerbating mental health inequalities, longer-term studies are only now emerging.: Method: In total, 34 465 individuals ... ...

    Abstract Background: While studies from the start of the COVID-19 pandemic have described initial negative effects on mental health and exacerbating mental health inequalities, longer-term studies are only now emerging.
    Method: In total, 34 465 individuals in the UK completed online questionnaires and were re-contacted over the first 12 months of the pandemic. We used growth mixture modelling to identify trajectories of depression, anxiety and anhedonia symptoms using the 12-month data. We identified sociodemographic predictors of trajectory class membership using multinomial regression models.
    Results: Most participants had consistently low symptoms of depression or anxiety over the year of assessments (60%, 69% respectively), and a minority had consistently high symptoms (10%, 15%). We also identified participants who appeared to show improvements in symptoms as the pandemic progressed, and others who showed the opposite pattern, marked symptom worsening, until the second national lockdown. Unexpectedly, most participants showed stable low positive affect, indicating anhedonia, throughout the 12-month period. From regression analyses, younger age, reporting a previous mental health diagnosis, non-binary, or self-defined gender, and an unemployed or a student status were significantly associated with membership of the stable high symptom groups for depression and anxiety.
    Conclusions: While most participants showed little change in their depression and anxiety symptoms across the first year of the pandemic, we highlight the divergent responses of subgroups of participants, who fared both better and worse around national lockdowns. We confirm that previously identified predictors of negative outcomes in the first months of the pandemic also predict negative outcomes over a 12-month period.
    Language English
    Publishing date 2022-12-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 217420-0
    ISSN 1469-8978 ; 0033-2917
    ISSN (online) 1469-8978
    ISSN 0033-2917
    DOI 10.1017/S0033291722003828
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Sociodemographic, mental health, and physical health factors associated with participation within re-contactable mental health cohorts: an investigation of the GLAD Study.

    Bright, Steven J / Hübel, Christopher / Young, Katherine S / Bristow, Shannon / Peel, Alicia J / Rayner, Christopher / Mundy, Jessica / Palmos, Alish B / Purves, Kirstin L / Kalsi, Gursharan / Armour, Cherie / Jones, Ian R / Hotopf, Matthew / McIntosh, Andrew M / Smith, Daniel J / Walters, James T R / Rogers, Henry C / Thompson, Katherine N / Adey, Brett N /
    Monssen, Dina / Kakar, Saakshi / Malouf, Chelsea M / Hirsch, Colette / Glen, Kiran / Kelly, Emily J / Veale, David / Eley, Thalia C / Breen, Gerome / Davies, Molly R

    BMC psychiatry

    2023  Volume 23, Issue 1, Page(s) 542

    Abstract: Background: The Genetic Links to Anxiety and Depression (GLAD) Study is a large cohort of individuals with lifetime anxiety and/or depression, designed to facilitate re-contact of participants for mental health research. At the start of the pandemic, ... ...

    Abstract Background: The Genetic Links to Anxiety and Depression (GLAD) Study is a large cohort of individuals with lifetime anxiety and/or depression, designed to facilitate re-contact of participants for mental health research. At the start of the pandemic, participants from three cohorts, including the GLAD Study, were invited to join the COVID-19 Psychiatry and Neurological Genetics (COPING) study to monitor mental and neurological health. However, previous research suggests that participation in longitudinal studies follows a systematic, rather than random, process, which can ultimately bias results. Therefore, this study assessed participation biases following the re-contact of GLAD Study participants.
    Methods: In April 2020, all current GLAD Study participants (N = 36,770) were invited to the COPING study. Using logistic regression, we investigated whether sociodemographic, mental, and physical health characteristics were associated with participation in the COPING baseline survey (aim one). Subsequently, we used a zero-inflated negative binomial regression to examine whether these factors were also related to participation in the COPING follow-up surveys (aim two).
    Results: For aim one, older age, female gender identity, non-binary or self-defined gender identities, having one or more physical health disorders, and providing a saliva kit for the GLAD Study were associated with an increased odds of completing the COPING baseline survey. In contrast, lower educational attainment, Asian or Asian British ethnic identity, Black or Black British ethnic identity, higher alcohol consumption at the GLAD sign-up survey, and current or ex-smoking were associated with a reduced odds. For aim two, older age, female gender, and saliva kit provision were associated with greater COPING follow-up survey completion. Lower educational attainment, higher alcohol consumption at the GLAD Study sign-up, ex-smoking, and self-reported attention deficit hyperactivity disorder had negative relationships.
    Conclusions: Participation biases surrounding sociodemographic and physical health characteristics were particularly evident when re-contacting the GLAD Study volunteers. Factors associated with participation may vary depending on study design. Researchers should examine the barriers and mechanisms underlying participation bias in order to combat these issues and address recruitment biases in future studies.
    MeSH term(s) Humans ; Male ; Female ; Mental Health ; Depression ; COVID-19 ; Gender Identity ; Anxiety
    Language English
    Publishing date 2023-07-26
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2050438-X
    ISSN 1471-244X ; 1471-244X
    ISSN (online) 1471-244X
    ISSN 1471-244X
    DOI 10.1186/s12888-023-04890-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The United Kingdom Eating Disorders Genetics Initiative.

    Monssen, Dina / Davies, Helena L / Kakar, Saakshi / Bristow, Shannon / Curzons, Susannah C B / Davies, Molly R / Kelly, Emily J / Ahmad, Zain / Bradley, John R / Bright, Steven / Coleman, Jonathan R I / Glen, Kiran / Hotopf, Matthew / Ter Kuile, Abigail R / Malouf, Chelsea Mika / Kalsi, Gursharan / Kingston, Nathalie / McAtarsney-Kovacs, Monika / Mundy, Jessica /
    Peel, Alicia J / Palmos, Alish B / Rogers, Henry C / Skelton, Megan / Adey, Brett N / Lee, Sang Hyuck / Virgo, Hope / Quinn, Tom / Price, Tom / Zvrskovec, Johan / Eley, Thalia C / Treasure, Janet / Hübel, Christopher / Breen, Gerome

    The International journal of eating disorders

    2023  Volume 57, Issue 5, Page(s) 1145–1159

    Abstract: Objective: The United Kingdom Eating Disorders Genetics Initiative (EDGI UK), part of the National Institute for Health and Care Research (NIHR) Mental Health BioResource, aims to deepen our understanding of the environmental and genetic etiology of ... ...

    Abstract Objective: The United Kingdom Eating Disorders Genetics Initiative (EDGI UK), part of the National Institute for Health and Care Research (NIHR) Mental Health BioResource, aims to deepen our understanding of the environmental and genetic etiology of eating disorders. EDGI UK launched in February 2020 and is partnered with the UK eating disorders charity, Beat. Multiple EDGI branches exist worldwide. This article serves the dual function of providing an in-depth description of our study protocol and of describing our initial sample including demographics, diagnoses, and physical and psychiatric comorbidities.
    Method: EDGI UK recruits via media and clinical services. Anyone living in England, at least 16 years old, with a lifetime probable or clinical eating disorder is eligible to sign up online: edgiuk.org. Participants complete online questionnaires, donate a saliva sample for genetic analysis, and consent to medical record linkage and recontact for future studies.
    Results: As of September 2022, EDGI UK recruited 7435 survey participants: 98% female, 93.1% white, 97.8% cisgender, 65.9% heterosexual, and 52.1% have a university degree. Over half (57.8%) of these participants have returned their saliva DNA kit. The most common diagnoses are anorexia nervosa (48.3%), purging disorder (37.8%), bulimia nervosa (37.5%), binge-eating disorder (15.8%), and atypical anorexia nervosa (7.8%).
    Conclusion: EDGI UK is the largest UK eating disorders study and efforts to increase its diversity are underway. It offers a unique opportunity to accelerate eating disorder research. Researchers and participants with lived experience can collaborate on projects with unparalleled sample size.
    Public significance statement: Eating disorders are debilitating and costly for society but are under-researched due to underfunding. EDGI UK is one of the largest eating disorder studies worldwide with ongoing recruitment. The collected data constitute a resource for secondary analysis. We will combine data from all international EDGI branches and the NIHR BioResource to facilitate research that improves our understanding of eating disorders and their comorbidities.
    MeSH term(s) Humans ; Feeding and Eating Disorders/genetics ; United Kingdom ; Female ; Male ; Adult ; Adolescent ; Surveys and Questionnaires ; Young Adult ; Middle Aged
    Language English
    Publishing date 2023-08-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603170-5
    ISSN 1098-108X ; 0276-3478
    ISSN (online) 1098-108X
    ISSN 0276-3478
    DOI 10.1002/eat.24037
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    Zs.A 1749: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Risk and protective factors for new-onset binge eating, low weight, and self-harm symptoms in >35,000 individuals in the UK during the COVID-19 pandemic.

    Davies, Helena L / Hübel, Christopher / Herle, Moritz / Kakar, Saakshi / Mundy, Jessica / Peel, Alicia J / Ter Kuile, Abigail R / Zvrskovec, Johan / Monssen, Dina / Lim, Kai Xiang / Davies, Molly R / Palmos, Alish B / Lin, Yuhao / Kalsi, Gursharan / Rogers, Henry C / Bristow, Shannon / Glen, Kiran / Malouf, Chelsea Mika / Kelly, Emily J /
    Purves, Kirstin L / Young, Katherine S / Hotopf, Matthew / Armour, Cherie / McIntosh, Andrew M / Eley, Thalia C / Treasure, Janet / Breen, Gerome

    The International journal of eating disorders

    2022  Volume 56, Issue 1, Page(s) 91–107

    Abstract: Objective: The disruption caused by the COVID-19 pandemic has been associated with poor mental health, including increases in eating disorders and self-harm symptoms. We investigated risk and protective factors for the new onset of these symptoms during ...

    Abstract Objective: The disruption caused by the COVID-19 pandemic has been associated with poor mental health, including increases in eating disorders and self-harm symptoms. We investigated risk and protective factors for the new onset of these symptoms during the pandemic.
    Method: Data were from the COVID-19 Psychiatry and Neurological Genetics study and the Repeated Assessment of Mental health in Pandemics Study (n = 36,715). Exposures were socio-demographic characteristics, lifetime psychiatric disorder, and COVID-related variables, including SARS-CoV-2 infection/illness with COVID-19. We identified four subsamples of participants without pre-pandemic experience of our outcomes: binge eating (n = 24,211), low weight (n = 24,364), suicidal and/or self-harm ideation (n = 18,040), and self-harm (n = 29,948). Participants reported on our outcomes at frequent intervals (fortnightly to monthly). We fitted multiple logistic regression models to identify factors associated with the new onset of our outcomes.
    Results: Within each subsample, new onset was reported by: 21% for binge eating, 10.8% for low weight, 23.5% for suicidal and/or self-harm ideation, and 3.5% for self-harm. Shared risk factors included having a lifetime psychiatric disorder, not being in paid employment, higher pandemic worry scores, and being racially minoritized. Conversely, infection with SARS-CoV-2/illness with COVID-19 was linked to lower odds of binge eating, low weight, and suicidal and/or self-harm ideation.
    Discussion: Overall, we detected shared risk factors that may drive the comorbidity between eating disorders and self-harm. Subgroups of individuals with these risk factors may require more frequent monitoring during future pandemics.
    Public significance: In a sample of 35,000 UK residents, people who had a psychiatric disorder, identified as being part of a racially minoritized group, were not in paid employment, or were more worried about the pandemic were more likely to experience binge eating, low weight, suicidal and/or self-harm ideation, and self-harm for the first time during the pandemic. People with these risk factors may need particular attention during future pandemics to enable early identification of new psychiatric symptoms.
    MeSH term(s) Humans ; COVID-19/epidemiology ; Pandemics ; Binge-Eating Disorder/epidemiology ; Protective Factors ; SARS-CoV-2 ; Self-Injurious Behavior/epidemiology ; Self-Injurious Behavior/psychology ; Suicidal Ideation ; Risk Factors ; Bulimia ; United Kingdom/epidemiology
    Language English
    Publishing date 2022-10-31
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 603170-5
    ISSN 1098-108X ; 0276-3478
    ISSN (online) 1098-108X
    ISSN 0276-3478
    DOI 10.1002/eat.23834
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1749: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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