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  1. Article ; Online: Affenpocken: Bilder eines klinischen Verlaufes.

    Potthoff, Anja / Brockmeyer, Norbert H / Skaletz-Rorowski, Adriane

    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

    2023  Volume 21, Issue 3, Page(s) 283–284

    Language English
    Publishing date 2023-03-16
    Publishing country Germany
    Document type Letter
    ZDB-ID 2093479-8
    ISSN 1610-0387 ; 1610-0379
    ISSN (online) 1610-0387
    ISSN 1610-0379
    DOI 10.1111/ddg.14981_g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6148: Show issues Location:
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  2. Article ; Online: Monkey pox: Images of a clinical course.

    Potthoff, Anja / Brockmeyer, Norbert H / Skaletz-Rorowski, Adriane

    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

    2023  Volume 21, Issue 3, Page(s) 283–284

    MeSH term(s) Humans ; Mpox (monkeypox) ; Disease Progression
    Language English
    Publishing date 2023-02-14
    Publishing country Germany
    Document type Letter
    ZDB-ID 2093479-8
    ISSN 1610-0387 ; 1610-0379
    ISSN (online) 1610-0387
    ISSN 1610-0379
    DOI 10.1111/ddg.14981
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  3. Article ; Online: Positiver Mycoplasma genitalium-Befund im Auge: ein Fall aus der Praxis.

    Mordhorst, Isabel / Potthoff, Anja / Brockmeyer, Norbert H

    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

    2021  Volume 19 Suppl 1, Page(s) 34–36

    Language English
    Publishing date 2021-04-09
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2093479-8
    ISSN 1610-0387 ; 1610-0379
    ISSN (online) 1610-0387
    ISSN 1610-0379
    DOI 10.1111/ddg.14482
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  4. Article ; Online: Self-DNA Sensing Fuels HIV-1-Associated Inflammation.

    Heil, Martin / Brockmeyer, Norbert H

    Trends in molecular medicine

    2019  Volume 25, Issue 11, Page(s) 941–954

    Abstract: Inflammation, over-reacting innate immunity, and ... ...

    Abstract Inflammation, over-reacting innate immunity, and CD4
    MeSH term(s) Alarmins/immunology ; Alarmins/metabolism ; Autoimmune Diseases/pathology ; DNA/immunology ; DNA/metabolism ; Extracellular Vesicles/metabolism ; HIV Infections/immunology ; HIV Infections/pathology ; HIV-1/immunology ; Inflammasomes/metabolism ; Inflammation/pathology ; Pyroptosis/immunology
    Chemical Substances Alarmins ; Inflammasomes ; DNA (9007-49-2)
    Language English
    Publishing date 2019-07-09
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2036490-8
    ISSN 1471-499X ; 1471-4914
    ISSN (online) 1471-499X
    ISSN 1471-4914
    DOI 10.1016/j.molmed.2019.06.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Rückblick auf den 63. Deutschen STI-Kongress 2018 in Bochum.

    Meyer, Thomas / Brockmeyer, Norbert H

    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

    2018  Volume 16, Issue 8, Page(s) 1070

    Language English
    Publishing date 2018-08-16
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2093479-8
    ISSN 1610-0387 ; 1610-0379
    ISSN (online) 1610-0387
    ISSN 1610-0379
    DOI 10.1111/ddg.13587
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  6. Book: HIV-Infekt

    Brockmeyer, Norbert H.

    Pathogenese - Diagnostik - Therapie ; mit 28 Tabellen

    1997  

    Author's details N. H. Brockmeyer ... (Hrsg.)
    Keywords HIV Infections / etiology ; HIV Infections / diagnosis ; HIV Infections / therapy ; HIV-Infektion
    Subject HIV
    Language German
    Size VIII, 181 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place Berlin u.a.
    Document type Book
    HBZ-ID HT007555777
    ISBN 3-540-62544-5 ; 978-3-540-62544-5
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    1997 A 7709 order for loan Magazin

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  7. Article ; Online: Cholesterol-conjugated siRNAs silence gene expression in mucosal dendritic cells in cervicovaginal tissue in mice.

    Basar, Emre / Shum, Bennett / Skaletz-Rorowski, Adriane / Wu, Yichao / Nambiar, Sandeep / Brockmeyer, Norbert H

    Journal of the European Academy of Dermatology and Venereology : JEADV

    2022  Volume 37, Issue 3, Page(s) 615–626

    Abstract: Background: RNA interference (RNAi) provides a powerful way to investigate the role of genes in disease pathogenesis and modulate gene expression to treat disease. In 2018, the FDA approved patisiran, the first RNAi-based drug, hence paving the way for ... ...

    Abstract Background: RNA interference (RNAi) provides a powerful way to investigate the role of genes in disease pathogenesis and modulate gene expression to treat disease. In 2018, the FDA approved patisiran, the first RNAi-based drug, hence paving the way for a novel class of RNAi therapeutics. Harnessing RNAi to inhibit vaginal HIV transmission requires effective gene silencing in immune cells, which remains difficult. Knockdown in accessible mucosal tissues may be easier than systemic gene silencing. Vaginally applied cholesterol-conjugated small interfering RNAs (chol-siRNAs) blocked herpes simplex virus transmission in mice without tissue damage or immunostimulation.
    Objectives and methods: To investigate using flow cytometry, confocal microscopy, and quantitative imaging if chol-siRNAs silence gene expression in vaginal immune cells in mice.
    Results: Although chol-siRNAs and lipoplexed-siRNAs silence gene expression in dendritic cells (DCs) in vitro, most internalized siRNAs concentrate within multivesicular bodies, where they are inaccessible to the cellular RNAi machinery. When applied intravaginally in vivo, chol-siRNAs penetrate the vaginal mucosa, including the lamina propria, and are efficiently internalized by intraepithelial (IE) and lamina propria (LP) DCs, and CD11b
    Conclusion: As mucosal DCs play an essential role for mucosal viral entry and dissemination, chol-siRNAs could be harnessed to target various host factors that are critical for viral uptake, DC migration and trans-infection of virions to T cells, hence allowing the development of a preventive vaginal HIV microbicide. Furthermore, chol-siRNAs could help elucidate the pathways of HIV transmission and understand the immunologic function of DCs in the genital tract.
    MeSH term(s) Female ; Mice ; Animals ; RNA Interference ; HIV Infections ; Dendritic Cells/metabolism ; Mucous Membrane ; Gene Expression
    Language English
    Publishing date 2022-11-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 1128828-0
    ISSN 1468-3083 ; 0926-9959
    ISSN (online) 1468-3083
    ISSN 0926-9959
    DOI 10.1111/jdv.18718
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  8. Article ; Online: Relevance of Regional Epidemiology of Retroviral Coinfections: HIV and Human T-Lymphotropic Virus.

    Potthoff, Anja / Nambiar, Sandeep / Brockmeyer, Norbert H

    AIDS research and human retroviruses

    2019  Volume 35, Issue 7, Page(s) 597

    MeSH term(s) Antibodies, Viral/blood ; Coinfection/diagnosis ; Coinfection/epidemiology ; Germany/epidemiology ; HIV Infections/diagnosis ; HIV Infections/epidemiology ; HTLV-I Infections/diagnosis ; HTLV-I Infections/epidemiology ; HTLV-II Infections/diagnosis ; HTLV-II Infections/epidemiology ; Human T-lymphotropic virus 1/immunology ; Human T-lymphotropic virus 1/isolation & purification ; Human T-lymphotropic virus 2/immunology ; Human T-lymphotropic virus 2/isolation & purification ; Humans
    Chemical Substances Antibodies, Viral
    Language English
    Publishing date 2019-05-02
    Publishing country United States
    Document type Letter
    ZDB-ID 639130-8
    ISSN 1931-8405 ; 0889-2229
    ISSN (online) 1931-8405
    ISSN 0889-2229
    DOI 10.1089/AID.2019.0045
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    Zs.A 1928: Show issues Location:
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  9. Article ; Online: Zum Artikel "HPV73 und HPV82 positives Analrandkarzinom mit sekundärer Überlagerung durch eine ulzerierende Herpes simplex Virus Typ 2 Infektion" (Kreuter, Potthoff, Brockmeyer, Stückland, KompNet HIV/AIDS).

    Brockmeyer, Norbert H

    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

    2011  Volume 9, Issue 8, Page(s) 579–580

    Title translation Comment on the article "HPV73 and HPV82 positive anal carcinoma with secondary ulcerating herpes simplex type 2 infection" (Kreuter, Potthoff, Brockmeyer, Stückland, KompNet HIV/AIDS).
    MeSH term(s) AIDS-Related Opportunistic Infections/diagnosis ; AIDS-Related Opportunistic Infections/virology ; Anus Neoplasms/diagnosis ; Anus Neoplasms/virology ; Carcinoma in Situ/diagnosis ; Carcinoma in Situ/virology ; Female ; Herpes Genitalis/diagnosis ; Herpes Genitalis/virology ; Herpesvirus 2, Human ; Humans ; Male ; Papillomavirus Infections/diagnosis ; Papillomavirus Infections/virology ; Superinfection/diagnosis ; Superinfection/virology
    Language German
    Publishing date 2011-08
    Publishing country Germany
    Document type Comment ; Editorial
    ZDB-ID 2093479-8
    ISSN 1610-0387 ; 1610-0379
    ISSN (online) 1610-0387
    ISSN 1610-0379
    DOI 10.1111/j.1610-0387.2011.07739.x
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  10. Article ; Online: Am Bildschirm über sexuelle Gesundheit sprechen : Erkenntnisse zum Einsatz von Online-Fokusgruppen in der empirischen Sozialforschung.

    Wirtz, Angelika / Brockmeyer, Norbert H / Langanke, Harriet / Skaletz-Rorowski, Adriane / Kayser, Arne / Köhler, Britta

    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete

    2021  Volume 72, Issue 2, Page(s) 175–177

    Title translation Online communication about sexual health : Findings on the use of online focus groups in empirical social research.
    MeSH term(s) Communication ; Focus Groups ; Humans ; Sexual Behavior ; Sexual Health
    Language German
    Publishing date 2021-01-05
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2403-x
    ISSN 1432-1173 ; 0017-8470
    ISSN (online) 1432-1173
    ISSN 0017-8470
    DOI 10.1007/s00105-020-04735-8
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