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Artikel: Massively parallel base editing screens to map variant effects on anti-tumor hallmarks of primary human T cells.

Walsh, Zachary H / Shah, Parin / Kothapalli, Neeharika / Nikolenyi, Gergo / Shah, Shivem B / Leuzzi, Giuseppe / Mu, Michael / Ho, Patricia / Abuzaid, Sinan / Brodtman, Zack D / Vasan, Neil / AlQuraishi, Mohammed / Milner, Joshua D / Ciccia, Alberto / Melms, Johannes C / Izar, Benjamin

bioRxiv : the preprint server for biology

2023  

Abstract: Base editing enables generation of single nucleotide variants, but large-scale screening in primary human T cells is limited due to low editing efficiency, among other ... ...

Abstract Base editing enables generation of single nucleotide variants, but large-scale screening in primary human T cells is limited due to low editing efficiency, among other challenges
Sprache Englisch
Erscheinungsdatum 2023-12-14
Erscheinungsland United States
Dokumenttyp Preprint
DOI 10.1101/2023.12.13.571465
Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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