Article ; Online: Successful Optimization of Tobacco Dependence Treatment in the Emergency Department: A Randomized Controlled Trial Using the Multiphase Optimization Strategy.
2022 Volume 81, Issue 2, Page(s) 209–221
Abstract: Study objective: Tobacco dependence treatment initiated in the hospital emergency department (ED) is effective. However, trials typically use multicomponent interventions, making it difficult to distinguish specific components that are effective. In ... ...
| Abstract | Study objective: Tobacco dependence treatment initiated in the hospital emergency department (ED) is effective. However, trials typically use multicomponent interventions, making it difficult to distinguish specific components that are effective. In addition, interactions between components cannot be assessed. The Multiphase Optimization Strategy allows investigators to identify these effects. Methods: We conducted a full-factorial, 2 Results: Between February 2017 and May 2019, we enrolled 1,056 adult smokers visiting the ED. Odd ratios (95% confidence intervals) from the primary analysis of biochemically confirmed abstinence rates at 3 months for each intervention, versus control, were: brief negotiation interview, 1.8 (1.1, 2.8); nicotine replacement therapy, 2.1 (1.3, 3.2); quitline, 1.4 (0.9, 2.2); SmokefreeTXT, 1.1 (0.7, 1.7). There were no statistically significant interactions among components. Economic and qualitative analyses are in progress. Conclusion: The brief negotiation interview and nicotine replacement therapy were efficacious. This study is the first to identify components of ED-initiated tobacco dependence treatment that are individually effective. Future work will address the scalability of the brief negotiation interview and nicotine replacement therapy by offering provider-delivered brief negotiation interviews and nicotine replacement therapy prescriptions. |
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| MeSH term(s) | Adult ; Humans ; Tobacco Use Disorder/therapy ; Smoking Cessation/methods ; Tobacco Use Cessation Devices ; Treatment Outcome ; Alcoholism ; Emergency Service, Hospital | |||||
| Language | English | |||||
| Publishing date | 2022-12-28 | |||||
| Publishing country | United States | |||||
| Document type | Randomized Controlled Trial ; Journal Article | |||||
| ZDB-ID | 603080-4 | |||||
| ISSN | 1097-6760 ; 0196-0644 | |||||
| ISSN (online) | 1097-6760 | |||||
| ISSN | 0196-0644 | |||||
| DOI | 10.1016/j.annemergmed.2022.08.018 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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