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Article ; Online: Working and working out: Decision-making inputs connect daily work demands to physical exercise.

Smith, Claire E / Lee, Soomi / Brooks, Margaret E / Barratt, Clare L / Yang, Haiyang

Journal of occupational health psychology

2023 Volume 28, Issue 3, Page(s) 160–173

Abstract: Work demands can undermine engagement in physical exercise, posing a threat to employee health and well-being. Integrating resource theories and a novel decision-making theory called the decision triangle, we propose that this effect may emerge because ... ...

Abstract	Work demands can undermine engagement in physical exercise, posing a threat to employee health and well-being. Integrating resource theories and a novel decision-making theory called the decision triangle, we propose that this effect may emerge because work stress changes the energetic and emotional processes people engage in when making decisions about exercise after work. Using diary-style data across two workweeks (N = 83 workers, 783 days), we used multilevel latent profile analysis to extract common decision input profiles, or daily configurations of energy and affect as key decision-making resources. Consistent with the decision triangle, three profiles emerged: visceral inputs (low energy/high negative affect), automatic inputs (low energy/low negative affect), and logical inputs (high energy/low negative affect). Daily job demands were highest among the visceral profile. In turn, the daily visceral profile related to the lowest likelihood of and intensity of physical exercise after work, especially relative to the daily logical profile. Whether or not those in the daily automatic profile exercised depended on their health orientation, or trait-level value of maintaining personal health. Our results support decision-making as a promising mechanism explaining the link between work demands and healthy leisure choices. Organizational interventions can target work stress, health orientation, or logical decision-making to promote frequent and vigorous employee physical exercise. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
MeSH term(s)	Humans ; Surveys and Questionnaires ; Emotions ; Occupational Stress ; Occupational Health ; Exercise
Language	English
Publishing date	2023-05-30
Publishing country	United States
Document type	Journal Article
ZDB-ID	1364901-2
ISSN	1939-1307 ; 1076-8998
ISSN (online)	1939-1307
ISSN	1076-8998
DOI	10.1037/ocp0000349
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Worth the Weight? Olanzapine Prescribing in Schizophrenia. A Review of Weight Gain and Other Cardiometabolic Side Effects of Olanzapine.

Fitzgerald, Ita / O'Dwyer, Sarah / Brooks, Margaret / Sahm, Laura / Crowley, Erin / Ní Dhubhlaing, Ciara

Frontiers in psychiatry

2021 Volume 12, Page(s) 730769

Language	English
Publishing date	2021-09-07
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564218-2
ISSN	1664-0640
ISSN	1664-0640
DOI	10.3389/fpsyt.2021.730769
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Review of orthopaedic trauma surgery during the peak of COVID-19 pandemic - An observational cohort study in the UK.

De, Chiranjit / Kainth, Nimrath / Harbham, Pratap Karavadra / Brooks, Margaret / Agarwal, Sujit

Journal of clinical orthopaedics and trauma

2021 Volume 20, Page(s) 101422

Abstract: Aim: This study aims to estimate the risk of acquiring medical complication or death from COVID-19 infection in patients who were admitted for orthopaedic trauma surgery during the peak and plateau of pandemic. Unlike other recently published studies, ... ...

Abstract	Aim: This study aims to estimate the risk of acquiring medical complication or death from COVID-19 infection in patients who were admitted for orthopaedic trauma surgery during the peak and plateau of pandemic. Unlike other recently published studies, where patient-cohort included a more morbid group and cancer surgeries, we report on a group of patients who had limb surgery and were more akin to elective orthopaedic surgery. Methods: The study included 214 patients who underwent orthopaedic trauma surgeries in the hospital between 12th March and 12th May-2020 when the pandemic was on the rise in the United Kingdom. Data was collected on demographic profile including comorbidities, ASA grade, COVID-19 testing, type of procedures and any readmissions, complications or mortality due to COVID-19. Results: There were 7.9% readmissions and 52.9% of it was for respiratory complications. Only one patient had positive COVID-19 test during readmission. 30-day mortality for trauma surgeries was 0% if hip fractures were excluded and 2.8% in all patients. All the mortalities were for proximal femur fracture surgeries and between ASA Grade 3 and 4 or in patients above the age of 70 years. Conclusion: This study suggests that presence of COVID-19 virus in the community and hospital did not adversely affect the outcome of orthopaedic trauma surgeries or lead to excess mortality or readmissions in patients undergoing limb trauma surgery. The findings also support resumption of elective orthopaedic surgeries with appropriate risk stratification, patient optimization and with adequate infrastructural support amidst the recovery phase of the pandemic.
Language	English
Publishing date	2021-04-21
Publishing country	India
Document type	Journal Article
ZDB-ID	2596956-0
ISSN	2213-3445 ; 0976-5662
ISSN (online)	2213-3445
ISSN	0976-5662
DOI	10.1016/j.jcot.2021.04.018
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Article ; Online: A Predictive Model of Adaptive Resistance to BRAF/MEK Inhibitors in Melanoma.

Ruiz, Emmanuelle M / Alhassan, Solomon A / Errami, Youssef / Abd Elmageed, Zakaria Y / Fang, Jennifer S / Wang, Guangdi / Brooks, Margaret A / Abi-Rached, Joe A / Kandil, Emad / Zerfaoui, Mourad

International journal of molecular sciences

2023 Volume 24, Issue 9

Abstract: The adaptive acquisition of resistance to BRAF and MEK inhibitor-based therapy is a common feature of melanoma cells and contributes to poor patient treatment outcomes. Leveraging insights from a proteomic study and publicly available transcriptomic data, ...

Abstract	The adaptive acquisition of resistance to BRAF and MEK inhibitor-based therapy is a common feature of melanoma cells and contributes to poor patient treatment outcomes. Leveraging insights from a proteomic study and publicly available transcriptomic data, we evaluated the predictive capacity of a gene panel corresponding to proteins differentially abundant between treatment-sensitive and treatment-resistant cell lines, deciphering predictors of treatment resistance and potential resistance mechanisms to BRAF/MEK inhibitor therapy in patient biopsy samples. From our analysis, a 13-gene signature panel, in both test and validation datasets, could identify treatment-resistant or progressed melanoma cases with an accuracy and sensitivity of over 70%. The dysregulation of HMOX1, ICAM, MMP2, and SPARC defined a BRAF/MEK treatment-resistant landscape, with resistant cases showing a >2-fold risk of expression of these genes. Furthermore, we utilized a combination of functional enrichment- and gene expression-derived scores to model and identify pathways, such as HMOX1-mediated mitochondrial stress response, as potential key drivers of the emergence of a BRAF/MEK inhibitor-resistant state in melanoma cells. Overall, our results highlight the utility of these genes in predicting treatment outcomes and the underlying mechanisms that can be targeted to reduce the development of resistance to BRAF/MEK targeted therapy.
MeSH term(s)	Humans ; Proto-Oncogene Proteins B-raf/genetics ; Proto-Oncogene Proteins B-raf/metabolism ; Proteomics ; Drug Resistance, Neoplasm/genetics ; Cell Line, Tumor ; Melanoma/drug therapy ; Melanoma/genetics ; Melanoma/metabolism ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use ; Mitogen-Activated Protein Kinase Kinases/metabolism
Chemical Substances	Proto-Oncogene Proteins B-raf (EC 2.7.11.1) ; Protein Kinase Inhibitors ; Mitogen-Activated Protein Kinase Kinases (EC 2.7.12.2) ; BRAF protein, human (EC 2.7.11.1)
Language	English
Publishing date	2023-05-07
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms24098407
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Status seeking and manipulative self-presentation

Highhouse, Scott / Brooks, Margaret E / Wang, Yi

International journal of selection and assessment Vol. 24, No. 4 , p. 352-361

2016 Volume 24, Issue 4, Page(s) 352–361

Author's details	Scott Highhouse, Margaret E. Brooks and Yi Wang
Keywords	Persönlichkeitsmerkmal ; Kompetenz ; Manipulation
Language	English
Publisher	Blackwell
Publishing place	Oxford [u.a.]
Document type	Article
ZDB-ID	1157355-7 ; 2027700-3
ISSN	1468-2389 ; 0965-075X
ISSN (online)	1468-2389
ISSN	0965-075X
Database	ECONomics Information System

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Article ; Online: The Psychosocial Benefits of Sport Participation During COVID-19 Are Only Partially Explained by Increased Physical Activity

Watson, Andrew M / Biese, Kevin / Reardon, Claudia / Schwarz, Allison / Haraldsdottir, Kristin / Brooks, Margaret Alison / Bell, David R / McGuine, Timothy

medRxiv

Abstract: The purpose of this study was to determine whether physical activity (PA) increases were responsible for the improvements in mental health and quality of life (QOL) seen among adolescents who returned to sport during the COVID-19 pandemic. Adolescent ... ...

Abstract	The purpose of this study was to determine whether physical activity (PA) increases were responsible for the improvements in mental health and quality of life (QOL) seen among adolescents who returned to sport during the COVID-19 pandemic. Adolescent athletes were asked to complete a survey in October 2020 regarding demographic information, whether they had returned to sport participation (no [DNP], yes [PLY]), school instruction type (virtual, in-person, hybrid), anxiety, depression, QOL, and PA. Anxiety, depression, QOL and PA were compared between PLY and DNP using least squares means from linear models adjusted for age, gender, and instruction type. Mediation analysis assessed whether the relationship between sport status and anxiety, depression, and QOL was mediated by PA. 171 athletes had returned to play, while 388 had not. PLY athletes had significantly lower anxiety (3.6 +/- 0.4 v 8.2 +/- 0.6, p < 0.001) and depression (4.2 +/- 0.4 v 7.3 +/- 0.6, p < 0.001), and significantly higher QOL (88.1 +/- 1.0 v 80.2 +/- 1.4, p < 0.001) and PA (24.0 +/- 0.5 v 16.3 +/- 0.7, p < 0.001). PA explained a significant, but relatively small portion of the difference in depression (22.1%, p = 0.02) and QOL (16.0%, p = 0.048) between PLY and DNP athletes, but did not explain the difference in anxiety (6.6%, p = 0.20). Increased PA is only responsible for a small portion of the improvements in depression and QOL among athletes who returned to sports and unrelated to improvements in anxiety. This suggests that the majority of the mental health benefits of sport participation for adolescents during the COVID-19 pandemic are independent of, and in addition to, the benefits of increased PA.
Keywords	covid19
Language	English
Publishing date	2022-01-11
Publisher	Cold Spring Harbor Laboratory Press
Document type	Article ; Online
DOI	10.1101/2022.01.11.22269077
Database	COVID19

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Article ; Online: Normative Values of the Sport Concussion Assessment Tool 3 (SCAT3) in High School Athletes.

Snedden, Traci R / Brooks, Margaret Alison / Hetzel, Scott / McGuine, Tim

Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine

2017 Volume 27, Issue 5, Page(s) 462–467

Abstract: Objective: Establish sex, age, and concussion history-specific normative baseline sport concussion assessment tool 3 (SCAT3) values in adolescent athletes.: Design: Prospective cohort.: Setting: Seven Wisconsin high schools.: Participants: ... ...

Abstract	Objective: Establish sex, age, and concussion history-specific normative baseline sport concussion assessment tool 3 (SCAT3) values in adolescent athletes. Design: Prospective cohort. Setting: Seven Wisconsin high schools. Participants: Seven hundred fifty-eight high school athletes participating in 19 sports. Independent variables: Sex, age, and concussion history. Main outcome measures: Sport Concussion Assessment Tool 3 (SCAT3): total number of symptoms; symptom severity; total Standardized Assessment of Concussion (SAC); and each SAC component (orientation, immediate memory, concentration, delayed recall); Balance Error Scoring System (BESS) total errors (BESS, floor and foam pad). Results: Males reported a higher total number of symptoms [median (interquartile range): 0 (0-2) vs 0 (0-1), P = 0.001] and severity of symptoms [0 (0-3) vs 0 (0-2), P = 0.001] and a lower mean (SD) total SAC [26.0 (2.3) vs 26.4 (2.0), P = 0.026], and orientation [5 (4-5) vs 5 (5-5), P = 0.021]. There was no difference in baseline scores between sex for immediate memory, concentration, delayed recall or BESS total errors. No differences were found for any test domain based on age. Previously, concussed athletes reported a higher total number of symptoms [1 (0-4) vs 0 (0-2), P = 0.001] and symptom severity [2 (0-5) vs 0 (0-2), P = 0.001]. BESS total scores did not differ by concussion history. Conclusion: This study represents the first published normative baseline SCAT3 values in high school athletes. Results varied by sex and history of previous concussion but not by age. The normative baseline values generated from this study will help clinicians better evaluate and interpret SCAT3 results of concussed adolescent athletes.
MeSH term(s)	Adolescent ; Athletes ; Athletic Injuries/diagnosis ; Attention ; Brain Concussion/diagnosis ; Female ; Humans ; Male ; Memory, Short-Term ; Mental Recall ; Neuropsychological Tests ; Orientation ; Postural Balance ; Prospective Studies ; Reference Values
Language	English
Publishing date	2017-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	1062530-6
ISSN	1536-3724 ; 1050-642X
ISSN (online)	1536-3724
ISSN	1050-642X
DOI	10.1097/JSM.0000000000000389
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Are common language effect sizes easier to understand than traditional effect sizes?

Brooks, Margaret E / Dalal, Dev K / Nolan, Kevin P

The Journal of applied psychology

2014 Volume 99, Issue 2, Page(s) 332–340

Abstract: Communicating the results of research to nonscientists presents many challenges. Among these challenges is communicating the effectiveness of an intervention in a way that people untrained in statistics can understand. Use of traditional effect size ... ...

Abstract	Communicating the results of research to nonscientists presents many challenges. Among these challenges is communicating the effectiveness of an intervention in a way that people untrained in statistics can understand. Use of traditional effect size metrics (e.g., r, r²) has been criticized as being confusing to general audiences. In response, researchers have developed nontraditional effect size indicators (e.g., binomial effect size display, common language effect size indicator) with the goal of presenting information in a more understandable manner. The studies described here present the first empirical test of these claims of understandability. Results show that nontraditional effect size indicators are perceived as more understandable and useful than traditional indicators for communicating the effectiveness of an intervention. People also rated training programs as more effective and were willing to pay more for programs whose effectiveness was described using the nontraditional effect size metrics.
MeSH term(s)	Adult ; Communication ; Comprehension ; Female ; Humans ; Male ; Mathematical Concepts ; Statistics as Topic ; Terminology as Topic ; Young Adult
Language	English
Publishing date	2014-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	219157-x
ISSN	1939-1854 ; 0021-9010
ISSN (online)	1939-1854
ISSN	0021-9010
DOI	10.1037/a0034745
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Book ; Online: Developing B2B Social Communities

Brooks, Margaret / Creek, Sam / Lovett, J. J

KEYS TO GROWTH, INNOVATION, AND CUSTOMER LOYALTY

2013

Abstract: Developing B2B Social Communities: Keys to Growth, Innovation, and Customer Loyalty explains why business-to-business companies need a robust online community strategy to survive and flourish in today’s changing economy and shows you how to design and ... ...

Author's details	by Margaret Brooks, J. J. Lovett, Sam Creek
Abstract	Developing B2B Social Communities: Keys to Growth, Innovation, and Customer Loyalty explains why business-to-business companies need a robust online community strategy to survive and flourish in today’s changing economy and shows you how to design and execute your company’s strategy successfully. Seminars, publications, market research, and customer care centers remain important tools in every B2B firm’s toolbox for understanding, attracting, and serving customers while keeping them loyal. But in a world of fierce global price competition, increasing transparency of business practices, and ever-rising complexity, these traditional customer interaction channels are no longer enough for most B2B companies. That’s why smart organizations-both large and small-are tapping into online communities to gain a huge competitive advantage: the ability to get much closer to customers and become more valuable to them. Developing B2B Social Communities delves into the generators of business value in online communities: immediate customer access to expert information within the company and from other customers; inexpensive delivery of custom technical help; demonstrations of how customers can to get the most from their products; and forums where customers can share tips, air gripes, reveal unmet needs, and suggest improvements. Three veteran community managers show you how to harness the knowledge of the crowd to help shape your company’s strategic direction, develop new products and services, identify trends, sell more, serve customers more efficiently, and provide better product support. Fleshing out precepts with real-world examples and case studies, the authors detail the transformational opportunities-and pitfalls-for creating online communities
Keywords	Computer industry ; Computer science ; Computer Einsteiger / Grundlagen
Language	English
Size	Online-Ressource (204 p), online resource
Publisher	Apress
Publishing place	Berkeley, CA ;s.l
Document type	Book ; Online
Note	Includes bibliographical references and index
ISBN	9781430247135 ; 9781430247142 ; 1430247134 ; 1430247142
DOI	10.1007/978-1-4302-4714-2
Database	Former special subject collection: coastal and deep sea fishing

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Book ; Online: Developing B2B social communities

Brooks, Margaret / Creek, Sam / Lovett, John J

keys to growth, innovation, and customer loyalty

2013

Abstract: Developing B2B Social Communities: Keys to Growth, Innovation, and Customer Loyalty explains why business-to-business companies need a robust online community strategy to survive and flourish in today's changing economy and shows you how to design and ... ...

Title variant	Developing business-to-business social communities
Author's details	Margaret Brooks, J.J. Lovett, Sam Creek
Abstract	Developing B2B Social Communities: Keys to Growth, Innovation, and Customer Loyalty explains why business-to-business companies need a robust online community strategy to survive and flourish in today's changing economy and shows you how to design and execute your company's strategy successfully.Seminars, publications, market research, and customer care centers remain important tools in every B2B firm's toolbox for understanding, attracting, and serving customers while keeping them loyal. But in a world of fierce global price competition, increasing transparency of business practices, and ever
Keywords	Business/Data processing ; Communication in marketing ; Internet marketing ; World Wide Web
Language	English
Size	Online-Ressource (xiv, 187 p), ill
Publisher	CA Technologies Press
Publishing place	S.l. ;s.l
Document type	Book ; Online
Note	Includes bibliographical references and index ; Includes index
ISBN	1306161320 ; 1430247134 ; 9781306161329 ; 9781430247135 ; 9781430247142 ; 1430247142
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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