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  1. Article ; Online: Imaging and video of late preterm delivery by midline laparotomy due to incarcerated uterus: A case report and literature review of a rare but morbid condition.

    Taylor, A K L / Bartels, H C / Brophy, D P / O'Brien, D / Corcoran, S M

    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

    2024  

    Abstract: Incarcerated gravid uterus (IGU) is a rare and serious obstetric complication. IGU is defined as the entrapment of the gravid uterus between the pubic symphysis and the sacral promontory. The incidence of IGU is 1 in 3000-10 000 cases. IGU is associated ... ...

    Abstract Incarcerated gravid uterus (IGU) is a rare and serious obstetric complication. IGU is defined as the entrapment of the gravid uterus between the pubic symphysis and the sacral promontory. The incidence of IGU is 1 in 3000-10 000 cases. IGU is associated with significant obstetric complications, including preterm labor, intrauterine fetal death, growth restriction, renal failure, uterine ischemia/rupture and thrombosis. Here, we present the case of a primigravida with urinary retention at 14 weeks. On transabdominal ultrasound at 19+5/7 weeks the cervix was difficult to visualize, and the anterior uterine wall appeared thickened. The bladder was elongated superior to the uterus and the placenta was low-lying. Initially the patient was managed with intermittent self-catheterization, and subsequently indwelling catheterization was required from 22 weeks. At 30 weeks, the patient was transferred to a tertiary center and magnetic resonance imaging (MRI) was preformed due to challenging visualization of the cervix on ultrasound and the patient's continued symptoms of constipation and recurrent urinary infections. The MRI found a retroflexed gravid uterus, with vagina and endocervix displaced anteriorly and compressed by the gravid uterus. The findings were consistent with an incarcerated uterus. The patient subsequently had positive urinary cultures for Pseudomonas and rising creatinine. Given the obstructive uropathy and associated morbidity and mortality, a plan for elective pre-term delivery at 33+6/7 weeks was made. Delivery was by midline laparotomy, normal anatomy was restored after manual evacuation of the fundus from below the sacral promontory, and an uncomplicated lower segment transverse uterine cesarean section was performed.
    Language English
    Publishing date 2024-04-12
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80149-5
    ISSN 1879-3479 ; 0020-7292
    ISSN (online) 1879-3479
    ISSN 0020-7292
    DOI 10.1002/ijgo.15536
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Clinical and Survival Outcomes Using Percutaneous Cholecystostomy Tube Alone or Subsequent Interval Cholecystectomy to Treat Acute Cholecystitis.

    Fleming, Christina A / Ismail, M / Kavanagh, R G / Heneghan, H M / Prichard, R S / Geoghegan, J / Brophy, D P / McDermott, E W

    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

    2019  Volume 24, Issue 3, Page(s) 627–632

    Abstract: Background: Percutaneous cholecystostomy (PCT) is a safe method of gallbladder drainage in the setting of severe or complicated acute cholecystitis (AC), particularly in patients who are high-risk surgical candidates. Small case series suggest that PCT ... ...

    Abstract Background: Percutaneous cholecystostomy (PCT) is a safe method of gallbladder drainage in the setting of severe or complicated acute cholecystitis (AC), particularly in patients who are high-risk surgical candidates. Small case series suggest that PCT aids resolution of acute cholecystitis in up to 90% of patients. However, reluctance is observed in utilising PCT more frequently, due to concerns that we are committing comorbid patients to an interval surgical procedure for which they may not be suitable.
    Aim: The aim of this study was to assess the clinical and survival outcomes of PCT use, with particular emphasis on a subgroup of patients who did not proceed to cholecystectomy.
    Methods: A retrospective analysis was performed of all patients with severe acute cholecystitis who required PCT insertion in a tertiary referral hospital from 2010 to 2015. Patient demographics and clinical data including systemic inflammatory response (SIRS) scores at presentation, readmissions and clinical and survival outcomes were analysed. Statistical analysis was performed using SPSS v.22 and GraphPad Prism v.7.
    Results: In total, 157 patients (59% males) with AC underwent PCT insertion during the study period. Median age at presentation was 71 years (range 29-94). A median SIRS score of 3 was noted at presentation. Patients required a median of two cholecystostomy tube changes/replacements (range 1-10) during treatment. Transhepatic tube placement was the preferred approach (69%) with 31% of tubes being placed via transabdominal approach. Only 55% proceeded to interval cholecystectomy. Of the 70 patients treated with PCT alone, their median age was 75 years. In this subgroup, only 12.9% (n = 9) developed recurrent biliary sepsis necessitating readmission following initial resolution of symptoms and tube removal. All episodes of recurrent biliary sepsis presented within 6 months of index presentation, and definitive PCT removal in this group was performed at a median of 3 months. No difference in survival was observed between both groups.
    Conclusion: Almost 90% of patients with AC who are managed definitively with a PCT will recover uneventfully without recurrent sepsis following PCT removal. This is a viable option for older, comorbid patients who are unfit for surgical intervention and is not associated with significantly increased mortality.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Cholecystectomy ; Cholecystitis, Acute/surgery ; Cholecystostomy ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2019-03-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2012365-6
    ISSN 1873-4626 ; 1934-3213 ; 1091-255X
    ISSN (online) 1873-4626 ; 1934-3213
    ISSN 1091-255X
    DOI 10.1007/s11605-019-04194-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Inadvertent subclavian artery cannulation with a central venous catheter; successful retrieval using a minimally invasive technique.

    Redmond, C E / O'Donohoe, R / Breslin, D / Brophy, D P

    Irish medical journal

    2014  Volume 107, Issue 9, Page(s) 292–293

    Abstract: A 48-year-old lady was referred to our department as an emergency following an unsuccessful attempt at central venous catheter insertion, resulting in cannulation of the subclavian artery. She underwent angiography with removal of the catheter and ... ...

    Abstract A 48-year-old lady was referred to our department as an emergency following an unsuccessful attempt at central venous catheter insertion, resulting in cannulation of the subclavian artery. She underwent angiography with removal of the catheter and closure of the arteriotomy using an Angio-Seal device. While the optimal management of this scenario has yet to be defined, the use of this minimally invasive technique warrants consideration.
    Language English
    Publishing date 2014-10
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 193134-9
    ISSN 0332-3102 ; 0021-129X
    ISSN 0332-3102 ; 0021-129X
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  4. Article: Inadvertent subclavian artery cannulation with a central venous catheter; successful retrieval using a minimally invasive technique.

    Redmond, C E / O'Donohoe, R / Breslin, D / Brophy, D P

    Irish medical journal

    2014  Volume 107, Issue 9, Page(s) 292–293

    Abstract: A 48-year-old lady was referred to our department as an emergency following an unsuccessful attempt at central venous catheter insertion, resulting in cannulation of the subclavian artery. She underwent angiography with removal of the catheter and ... ...

    Abstract A 48-year-old lady was referred to our department as an emergency following an unsuccessful attempt at central venous catheter insertion, resulting in cannulation of the subclavian artery. She underwent angiography with removal of the catheter and closure of the arteriotomy using an Angio-Seal device. While the optimal management of this scenario has yet to be defined, the use of this minimally invasive technique warrants consideration.
    MeSH term(s) Angiography/methods ; Catheterization, Central Venous/adverse effects ; Device Removal/methods ; Female ; Hemostasis, Surgical/instrumentation ; Hemostasis, Surgical/methods ; Humans ; Intraoperative Complications/diagnosis ; Intraoperative Complications/physiopathology ; Intraoperative Complications/surgery ; Medical Errors ; Middle Aged ; Minimally Invasive Surgical Procedures/methods ; Subclavian Artery/injuries ; Treatment Outcome ; Vascular Closure Devices ; Vascular Surgical Procedures/methods ; Vascular System Injuries/diagnosis ; Vascular System Injuries/etiology ; Vascular System Injuries/physiopathology ; Vascular System Injuries/surgery
    Language English
    Publishing date 2014-10
    Publishing country Ireland
    Document type Case Reports ; Journal Article
    ZDB-ID 193134-9
    ISSN 0332-3102 ; 0021-129X
    ISSN 0332-3102 ; 0021-129X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Minimally invasive approaches to the management of anastomotic leakage following restorative rectal cancer resection.

    Creavin, B / Ryan, É J / Kelly, M E / Moynihan, A / Redmond, C E / Ahern, D / Kennelly, R / Hanly, A / Martin, S T / O'Connell, P R / Brophy, D P / Winter, D C

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2019  Volume 21, Issue 12, Page(s) 1364–1371

    Abstract: Aim: Management of anastomotic leakage (AL) following rectal resection has evolved with increasing use of less invasive techniques. The aim of this study was to review the management of AL following restorative rectal cancer resection in a tertiary ... ...

    Abstract Aim: Management of anastomotic leakage (AL) following rectal resection has evolved with increasing use of less invasive techniques. The aim of this study was to review the management of AL following restorative rectal cancer resection in a tertiary referral centre.
    Method: A retrospective review of a prospectively maintained database was performed. The primary outcome was successful management of AL. The secondary outcome was the impact of AL on oncological outcome.
    Results: Five hundred and two restorative rectal cancer resections were performed during the study period. The incidence of AL was 9.9% (n = 50). AL occurred more commonly following neoadjuvant chemoradiotherapy (n = 31/252, 12.3%) than in those who did not receive neoadjuvant chemoradiotherapy (n = 19/250, 7.6%; P = 0.107); however, this was not statistically significant. Successful minimally invasive drainage was achieved in 28 patients (56%, radiological n = 24, surgical n = 4). Trans-rectal drainage was the most common drainage method (n = 14). The median duration of drainage was longer in the neoadjuvant group (27 vs 18 days). Surgical intervention was required in 11 patients, with anastomotic takedown and end-colostomy formation was most commonly required. Successful management of AL with drainage (maintenance of the anastomosis without the need for further intervention) was achieved in 26 of the 28 patients. There were no significant differences in overall or disease-free survival when patients with AL were compared with patients without AL (69.4% vs 72.6%, P = 0.99 and 78.7% vs 71.3%, P = 0.45, respectively).
    Conclusion: In selected patients, AL following restorative rectal resection can be effectively controlled using minimally invasive radiological or surgical drainage without the need for further intervention.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Anal Canal/surgery ; Anastomosis, Surgical/adverse effects ; Anastomotic Leak/etiology ; Anastomotic Leak/therapy ; Chemoradiotherapy/adverse effects ; Databases, Factual ; Drainage/methods ; Female ; Humans ; Male ; Middle Aged ; Neoadjuvant Therapy/adverse effects ; Proctectomy/adverse effects ; Prospective Studies ; Rectal Neoplasms/surgery ; Rectum/surgery ; Retrospective Studies ; Tertiary Care Centers ; Transanal Endoscopic Surgery/methods ; Treatment Outcome
    Language English
    Publishing date 2019-07-17
    Publishing country England
    Document type Evaluation Study ; Journal Article
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.14742
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Successful arterial reconstruction and colectomy to treat severe visceral arterial disease with concomitant colon cancer.

    Redmond, C E / O'Donohoe, R / Brophy, D P / Maguire, D / Beddy, D

    Techniques in coloproctology

    2013  Volume 17, Issue 5, Page(s) 601–603

    MeSH term(s) Adenocarcinoma/pathology ; Adenocarcinoma/surgery ; Aged ; Anastomosis, Surgical/methods ; Angiography/methods ; Arterial Occlusive Diseases/diagnostic imaging ; Arterial Occlusive Diseases/physiopathology ; Arterial Occlusive Diseases/surgery ; Colectomy/methods ; Colonic Neoplasms/pathology ; Colonic Neoplasms/surgery ; Combined Modality Therapy ; Female ; Follow-Up Studies ; Humans ; Ileostomy/methods ; Imaging, Three-Dimensional ; Laparotomy/methods ; Mesenteric Artery, Inferior/diagnostic imaging ; Mesenteric Artery, Inferior/surgery ; Mesenteric Artery, Superior/diagnostic imaging ; Mesenteric Artery, Superior/surgery ; Mesentery/blood supply ; Neoplasm Invasiveness/pathology ; Neoplasm Staging ; Tomography, X-Ray Computed/methods ; Treatment Outcome
    Language English
    Publishing date 2013-05-17
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 2083309-X
    ISSN 1128-045X ; 1123-6337
    ISSN (online) 1128-045X
    ISSN 1123-6337
    DOI 10.1007/s10151-013-1006-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Treatment of iatrogenic femoral pseudoaneurysms with percutaneous thrombin injection: experience in 54 patients.

    Sheiman, R G / Brophy, D P

    Radiology

    2001  Volume 219, Issue 1, Page(s) 123–127

    Abstract: Purpose: To assess the clinical success of ultrasonography (US)-guided thrombin injection for the treatment of iatrogenic femoral pseudoaneurysms and to identify criteria that may predispose to treatment failure.: Materials and methods: Fifty-four ... ...

    Abstract Purpose: To assess the clinical success of ultrasonography (US)-guided thrombin injection for the treatment of iatrogenic femoral pseudoaneurysms and to identify criteria that may predispose to treatment failure.
    Materials and methods: Fifty-four iatrogenic femoral pseudoaneurysms were treated with US-guided thrombin injection. Forty-five were classified as simple (single lobe) and nine, as complex (at least two lobes and a single neck to the native vessel). Pseudoaneurysm volume, classification, thrombin dose, anticoagulation therapy status, and sheath size were compared between failed and successful cases. Seven- to 10-day follow-up US and a minimum 4-month clinical follow-up were also performed to evaluate success.
    Results: Fifty of 54 pseudoaneurysms were successfully treated with topical thrombin without complication and included all 45 simple and five of nine complex pseudoaneurysms. US follow-up in all 50 successful cases and clinical follow-up in 37 of these revealed no recurrence. Only a complex pseudoaneurysm classification was significantly associated with failure (P<.01). Among the complex pseudoaneurysms, successful cases involved two injections and a total thrombin dose of at least 1,500 units. In failed cases, pseudoaneurysms were treated with a single injection of 1,000 units, initially thrombosed, and recurred.
    Conclusion: Simple iatrogenic femoral pseudoaneurysms, regardless of size or concomitant anticoagulation therapy, can be treated with a single injection of up to 1,000 units of topical thrombin and require no follow-up. Complex pseudoaneurysms will likely require a second injection (total thrombin dose of at least 1,500 units) and short-term clinical and US follow-up to ensure successful treatment.
    MeSH term(s) Aged ; Aged, 80 and over ; Aneurysm, False/diagnostic imaging ; Aneurysm, False/drug therapy ; Cardiac Catheterization ; Female ; Femoral Artery/diagnostic imaging ; Femoral Artery/drug effects ; Femoral Artery/injuries ; Humans ; Iatrogenic Disease ; Injections, Intralesional ; Male ; Middle Aged ; Recurrence ; Thrombin/administration & dosage ; Treatment Failure ; Ultrasonography, Doppler, Color
    Chemical Substances Thrombin (EC 3.4.21.5)
    Language English
    Publishing date 2001-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80324-8
    ISSN 1527-1315 ; 0033-8419
    ISSN (online) 1527-1315
    ISSN 0033-8419
    DOI 10.1148/radiology.219.1.r01ap43123
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  8. Article: Optimal digital subtraction angiography of dorsalis pedis artery: effect of foot positioning on angiographic demonstration.

    Brophy, D P / Patel, S A

    Journal of vascular and interventional radiology : JVIR

    1999  Volume 10, Issue 3, Page(s) 376–377

    MeSH term(s) Angiography, Digital Subtraction/methods ; Angiography, Digital Subtraction/standards ; Chronic Disease ; Follow-Up Studies ; Foot/blood supply ; Humans ; Ischemia/diagnostic imaging ; Posture ; Tibial Arteries/diagnostic imaging
    Language English
    Publishing date 1999-03
    Publishing country United States
    Document type Comparative Study ; Letter ; Comment
    ZDB-ID 1137756-2
    ISSN 1535-7732 ; 1051-0443
    ISSN (online) 1535-7732
    ISSN 1051-0443
    DOI 10.1016/s1051-0443(99)70048-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Ireland's recent contribution to the radiological literature; a bibliometric analysis.

    Redmond, C E / Healy, G M / Ryan, D T / Conway, R / Murphy, C F / Ni Leidhin, C / Power, J / Brophy, D P / Heffernan, E J

    Irish medical journal

    2017  Volume 110, Issue 4, Page(s) 544

    Abstract: The aim of this study was to identify and analyse all articles published by Irish radiology departments in the medical literature since the year 2000. The PubMed database was searched to identify and review all articles published by radiologists based in ...

    Abstract The aim of this study was to identify and analyse all articles published by Irish radiology departments in the medical literature since the year 2000. The PubMed database was searched to identify and review all articles published by radiologists based in the Republic of Ireland or Northern Ireland. Citation counts were then obtained and the top ten most cited articles were identified. There were 781 articles published during the study period. Of these, 558 (71%) were published in radiology journals and the remaining 223 (29%) were published in general medical journals. Abdominal radiology was the most represented sub-specialty (33% of all articles). There was a general trend of increased publications per year. Only 75 (9.6%) of articles were collaborative efforts by more than one radiology department. Irish radiology departments have a considerable research output and this has increased since the year 2000. More collaborative research between Irish radiology departments is encouraged.
    MeSH term(s) Bibliometrics ; Biomedical Research ; Humans ; Ireland ; Northern Ireland ; Periodicals as Topic/statistics & numerical data ; PubMed ; Radiology/statistics & numerical data
    Language English
    Publishing date 2017-04-10
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 193134-9
    ISSN 0332-3102 ; 0021-129X
    ISSN 0332-3102 ; 0021-129X
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  10. Article ; Online: Secondary aortoenteric fistula presenting with small bowel obstruction.

    Killeen, R P / Moloney, M A / O'Donnell, D H / Sheehan, S / Brophy, D P

    Emergency medicine journal : EMJ

    2009  Volume 26, Issue 9, Page(s) 640

    MeSH term(s) Abdominal Pain/etiology ; Aged ; Aneurysm, False/complications ; Aneurysm, False/diagnostic imaging ; Aortic Aneurysm, Abdominal/surgery ; Aortic Diseases/complications ; Aortic Diseases/diagnostic imaging ; Blood Vessel Prosthesis ; Cecal Diseases/diagnostic imaging ; Cecal Diseases/etiology ; Female ; Humans ; Intestinal Fistula/complications ; Intestinal Fistula/diagnostic imaging ; Intestinal Obstruction/diagnostic imaging ; Intestinal Obstruction/etiology ; Jejunal Diseases/diagnostic imaging ; Jejunal Diseases/etiology ; Postoperative Complications/diagnostic imaging ; Postoperative Complications/etiology ; Tomography, X-Ray Computed ; Vascular Fistula/complications
    Language English
    Publishing date 2009-09
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2040124-3
    ISSN 1472-0213 ; 1472-0205
    ISSN (online) 1472-0213
    ISSN 1472-0205
    DOI 10.1136/emj.2008.062257
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