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  1. Article ; Online: Endovascular Cell Therapy Introducing an Anatomical Sparing Strategy in a Preclinical Model of Aortic Isthmus Saccular Aneurysm.

    Touma, Joseph / Brossier, Julien / Schneider, Fabrice / Rouard, Hélène / Gervais, Marianne / Allaire, Eric

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

    2021  Volume 62, Issue 2, Page(s) 312–313

    MeSH term(s) Actins/metabolism ; Angiography ; Animals ; Aortic Aneurysm, Thoracic/diagnostic imaging ; Aortic Aneurysm, Thoracic/pathology ; Aortic Aneurysm, Thoracic/therapy ; Elastin/ultrastructure ; Hydrogels ; Magnetic Resonance Imaging ; Mesenchymal Stem Cell Transplantation ; Organ Sparing Treatments ; Stents ; Swine ; Vascular Patency
    Chemical Substances Actins ; Hydrogels ; Elastin (9007-58-3)
    Language English
    Publishing date 2021-05-27
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 1225869-6
    ISSN 1532-2165 ; 1078-5884
    ISSN (online) 1532-2165
    ISSN 1078-5884
    DOI 10.1016/j.ejvs.2021.03.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Computer-assisted study of the axial orientation and distances between renovisceral arteries ostia.

    Lawton, James / Touma, Joseph / Sénémaud, Jean / de Boissieu, Paul / Brossier, Julien / Kobeiter, Hicham / Desgranges, Pascal

    Surgical and radiologic anatomy : SRA

    2017  Volume 39, Issue 2, Page(s) 149–160

    Abstract: Purpose: Endovascular navigation in aortic, renal and visceral procedures are based on precise knowledge of arterial anatomy. Our aim was to define the anatomical localization of the ostia of renovisceral arteries and their distribution to establish ... ...

    Abstract Purpose: Endovascular navigation in aortic, renal and visceral procedures are based on precise knowledge of arterial anatomy. Our aim was to define the anatomical localization of the ostia of renovisceral arteries and their distribution to establish anatomical landmarks for endovascular catheterization.
    Methods: Computer-assisted measurements performed on 55 CT scans and patients features (age, sex, aortic diameter) were analyzed. p values <0.05 were considered statistically significant.
    Results: The mean axial angulation of CeT and the SMA origin was 21.8° ± 10.1° and 9.9° ± 10.5°, respectively. The ostia were located on the left anterior edge of the aorta in 96 % of cases for the CeT and 73 % for the SMA. CeT and SMA angles followed Gaussian distribution. Left renal artery (LRA) rose at 96° ± 15° and in 67 % of cases on the left posterior edge. The right renal artery (RRA) rose at -62° ± 16.5° and in 98 % of cases on the right anterior edge of the aorta. RRA angle measurements and cranio-caudal RRA-LRA distance measurements did not follow Gaussian distribution. The mean distances between the CeT and the SMA, LRA, and RRA were 16.7 ± 5.0, 30.7 ± 7.9 and 30.5 ± 7.7 mm, respectively. CeT-SMA distance showed correlation with age and aortic diameter (p = 0.03). CeT-LRA distance showed correlation with age (p = 0.04). The mean distance between the renal ostia was 3.75 ± 0.21 mm. The RRA ostium was higher than the LRA ostium in 52 % of cases. RRA and LRA origins were located at the same level in 7 % of cases.
    Conclusion: Our results illustrate aortic elongation with ageing and high anatomical variability of renal arteries. Our findings are complementary to anatomical features previously published and might contribute to enhance endovascular procedures safety and efficacy for vascular surgeons and interventional radiologists.
    MeSH term(s) Age Factors ; Aged ; Anatomic Variation ; Aorta, Abdominal/anatomy & histology ; Celiac Artery/anatomy & histology ; Computed Tomography Angiography ; Contrast Media/administration & dosage ; Endovascular Procedures ; Female ; Humans ; Kidney/blood supply ; Male ; Mesenteric Artery, Superior/anatomy & histology ; Middle Aged ; Renal Artery/anatomy & histology ; Sex Factors
    Chemical Substances Contrast Media
    Language English
    Publishing date 2017-02
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 632839-8
    ISSN 1279-8517 ; 0930-312X ; 0930-1038
    ISSN (online) 1279-8517
    ISSN 0930-312X ; 0930-1038
    DOI 10.1007/s00276-016-1718-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Anatomic feasibility of endovascular treatment of abdominal aortic aneurysms in emergency in the era of the chimney technique: impact on an emergency endovascular kit.

    Brossier, Julien / Coscas, Raphaël / Capdevila, Clément / Kitzis, Michel / Coggia, Marc / Goeau-Brissonniere, Olivier

    Annals of vascular surgery

    2013  Volume 27, Issue 7, Page(s) 844–850

    Abstract: Background: Despite promising results, endovascular aortic repair (EVAR) of ruptured/painful abdominal aortic aneurysms (RPAAA) continues to have limited use due to anatomic constraints linked to RPAAA morphology. Currently, EVAR for RPAAA is reserved ... ...

    Abstract Background: Despite promising results, endovascular aortic repair (EVAR) of ruptured/painful abdominal aortic aneurysms (RPAAA) continues to have limited use due to anatomic constraints linked to RPAAA morphology. Currently, EVAR for RPAAA is reserved for patients presenting with a long infrarenal aortic neck, because commercially available fenestrated stent grafts are not available in an emergency setting. Recently, the chimney technique (ChT) has been utilized to treat infrarenal abdominal aortic aneurysms (AAA) with short necks, but this technique requires specific materials. The aim of this study was to determine the rate of RPAAA eligible for EVAR since the advent of the ChT and to ascertain the standard materials needed in this context.
    Methods: We carried out a retrospective study of patients operated on for RPAAA (<24 hours after admission) at our center between 2006 and 2011. Patients' computed tomography (CT) scans were analyzed by two independent operators using 3-dimensional reconstruction software with a centerline of flow. To perform standard EVAR, the anatomic criteria used were those provided by the manufacturer (proximal neck diameter 18-32 mm with length >15 mm, angulation <60°, iliac diameter >7 mm). ChT anatomic feasibility criteria were: (1) a healthy aortic area >15 mm between the renal arteries and celiac trunk; (2) caudal orientation of renal arteries; and (3) a healthy descending thoracic aorta. Patients were classified according to the feasibility or nonfeasibility of standard EVAR and ChT.
    Results: In total, over the period of study, 55 patients were operated on for RPAAA. In 5 patients (9%), CT scan quality was unsatisfactory and thus 50 patients (mean age 76 years, 75% men) were analyzed. Among them, 35 (70%) had a ruptured aneurysm and 17 (34%) were unstable. Anatomically, 22 (44%) patients were eligible for standard EVAR. Taking the ChT into consideration, an additional 11 (22%) patients were eligible for EVAR. Among these EVAR-eligible patients, mean proximal neck diameter was 23 ± 3 mm and stent grafts with 24-, 28-, and 32-mm diameters could fit in 33% (11 of 33), 51% (17 of 33), and 12% (4 of 33) of the cases, respectively. These results enabled us to determine the material that should be made available in the emergency setting in centers treating RPAAA. Among the 17 patients who were not eligible for EVAR, an iliac pathology (calcifications, stenosis) and a very hostile proximal neck (angulation, thrombus), respectively, were involved in 88% (15 of 17) and 12% (2 of 17) of the cases.
    Conclusions: The ChT increases EVAR feasibility by 50% in RPAAA. Taking into consideration our results, we recommend continued availability of emergency kits, including suitable aortouni-iliac stent grafts and basic material for performing ChT to allow surgeons to provide EVAR to the greatest number of RPAAA cases.
    MeSH term(s) Aged ; Aged, 80 and over ; Aortic Aneurysm, Abdominal/diagnostic imaging ; Aortic Aneurysm, Abdominal/surgery ; Aortic Rupture/diagnostic imaging ; Aortic Rupture/surgery ; Aortography/methods ; Blood Vessel Prosthesis ; Blood Vessel Prosthesis Implantation/adverse effects ; Blood Vessel Prosthesis Implantation/instrumentation ; Blood Vessel Prosthesis Implantation/methods ; Emergencies ; Emergency Service, Hospital/organization & administration ; Endovascular Procedures/adverse effects ; Endovascular Procedures/instrumentation ; Endovascular Procedures/methods ; Feasibility Studies ; Female ; Health Services Accessibility/organization & administration ; Humans ; Imaging, Three-Dimensional ; Male ; Patient Selection ; Predictive Value of Tests ; Prosthesis Design ; Radiographic Image Interpretation, Computer-Assisted ; Retrospective Studies ; Risk Factors ; Stents ; Tomography, X-Ray Computed ; Treatment Outcome
    Language English
    Publishing date 2013-10
    Publishing country Netherlands
    Document type Evaluation Studies ; Journal Article
    ZDB-ID 1027366-9
    ISSN 1615-5947 ; 0890-5096
    ISSN (online) 1615-5947
    ISSN 0890-5096
    DOI 10.1016/j.avsg.2012.05.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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