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  1. Article ; Online: Compressive cervicothoracic pseudomeningocele as a rare manifestation of idiopathic intrathecal hypotension after past trauma: a review.

    Gondar, Renato / Brouze, Iris F / Valsecchi, Daniele / Maestretti, Gianluca

    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

    2021  Volume 30, Issue 6, Page(s) 1451–1459

    Abstract: Purpose: Spontaneous intracranial or intrathecal hypotension (SIH) is an underdiagnosed phenomenon predominantly presenting with low cerebrospinal fluid (CSF) pressure and postural headache in the setting of CSF leak. Extrathecal CSF collections causing ...

    Abstract Purpose: Spontaneous intracranial or intrathecal hypotension (SIH) is an underdiagnosed phenomenon predominantly presenting with low cerebrospinal fluid (CSF) pressure and postural headache in the setting of CSF leak. Extrathecal CSF collections causing compression of the spinal cord or nerve roots present an even rarer subset of this disease. We aim to describe this pathology in a comprehensive manner while illustrating with a case of our own.
    Methods: We present a literature review on spinal idiopathic pseudomeningoceles and their neurological implications illustrated with a case of an anterior compressive pseudomeningocele between C2 and D7. Further investigations through a myelography and myelo-CT were able to postulate a CSF leak through a discogenic osteophytic microspur at the level C5-C6.
    Results: Spinal manifestations are uncommon in cases of idiopathic or spontaneous CSF leak, occurring in about 6% of patients, but myelopathy and radiculopathy involving all spinal segments do occur. In contrast to the cranial complaints, the spinal manifestations usually are not positional and are caused by mass effect from an extradural CSF collection.
    Conclusion: The utility of multiple imaging modalities such as dynamic myelography and the use of epidural blood patches and fibrin glue polymers should be explored, and surgery is an option if the symptoms persist despite other measures.
    MeSH term(s) Blood Patch, Epidural ; Cerebrospinal Fluid Leak/diagnostic imaging ; Cerebrospinal Fluid Leak/etiology ; Humans ; Hypotension ; Intracranial Hypotension/complications ; Intracranial Hypotension/diagnostic imaging ; Magnetic Resonance Imaging ; Myelography
    Language English
    Publishing date 2021-02-23
    Publishing country Germany
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 1115375-1
    ISSN 1432-0932 ; 0940-6719
    ISSN (online) 1432-0932
    ISSN 0940-6719
    DOI 10.1007/s00586-021-06766-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Pelvic tilt after Bernese periacetabular osteotomy-a long-term follow-up study.

    Heimann, Alexander F / Brouze, Iris F / Zheng, Guoyan / Moosmann, Angela M / Schwab, Joseph M / Tannast, Moritz / Zurmühle, Corinne A

    Journal of hip preservation surgery

    2023  Volume 10, Issue 3-4, Page(s) 214–219

    Abstract: Patients with developmental dysplasia of the hip (DDH) are believed to present with increased anterior pelvic tilt to compensate for reduced anterior femoral head coverage. If true, pelvic tilt in dysplastic patients should be high preoperatively and ... ...

    Abstract Patients with developmental dysplasia of the hip (DDH) are believed to present with increased anterior pelvic tilt to compensate for reduced anterior femoral head coverage. If true, pelvic tilt in dysplastic patients should be high preoperatively and decrease after correction with periacetabular osteotomy (PAO). To date, the evolution of pelvic tilt in long-term follow-up after PAO has not been reported. We therefore asked the following questions: (i) is there a difference in pelvic tilt between patients with DDH and an asymptomatic control group? (ii) How does pelvic tilt evolve during long-term follow-up after Bernese PAO compared with before surgery? This study is a therapeutic study with the level of evidence III. We retrospectively compared preoperative pelvic tilt in 64 dysplastic patients (71 hips) with an asymptomatic control group of 20 patients (20 hips). In addition, immediate postoperative and long-term follow-up (at 18 ± 8 [range 7-34 years) pelvic tilt was assessed and compared. Dysplastic patients had a significantly higher mean preoperative pelvic tilt than controls [2.3 ± 5.3° (-11.2° to 16.4°) versus 1.1 ± 3.0° (-4.9 to 5.9),
    Language English
    Publishing date 2023-09-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2773022-0
    ISSN 2054-8397
    ISSN 2054-8397
    DOI 10.1093/jhps/hnad030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Well leg compartment syndrome in trauma surgery - femoral shaft fracture treated by femoral intramedullary nailing in the hemilithotomy position: case series and review of the literature.

    Brouze, Iris F / Steinmetz, Sylvain / McManus, John / Borens, Olivier

    Therapeutics and clinical risk management

    2019  Volume 15, Page(s) 241–250

    Abstract: Well leg compartment syndrome (WLCS) is a rare complication which can occur following urological, gynecological, general surgical or orthopedic surgeries carried out with the lower limb in the hemilithotomy position. WLCS is associated with significant ... ...

    Abstract Well leg compartment syndrome (WLCS) is a rare complication which can occur following urological, gynecological, general surgical or orthopedic surgeries carried out with the lower limb in the hemilithotomy position. WLCS is associated with significant morbidity and mortality because delay in diagnosis and treatment can lead to loss of function and even life-threatening complications. During orthopedic surgeries on a traction table, such as femoral nailing, the contralateral "well leg" is often placed in the hemilithotomy position, thus facilitating the use of fluoroscopy. This position (also named the Lloyd-Davis position) consists of hip flexion, abduction, external rotation and knee flexion. We present the cases of two teenaged patients who underwent femoral nailing on an extension table of a femoral fracture and developed WLCS. We also present a review of the literature and a discussion of the pathophysiology, risk factors and treatment of this condition. Clinicians need to be aware of the risk factors for WLCS and have high index of suspicion. Further studies looking at the risks, benefits and feasibility of ways to reduce this risk are required.
    Language English
    Publishing date 2019-02-08
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2186560-7
    ISSN 1178-203X ; 1176-6336
    ISSN (online) 1178-203X
    ISSN 1176-6336
    DOI 10.2147/TCRM.S177530
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Lower 1-Year Postoperative Mortality After Acetabular Versus Proximal Femoral Fractures in Elderly Patients.

    Stetzelberger, Vera M / Brouze, Iris F / Steppacher, Simon D / Bastian, Johannes D / Schwab, Joseph M / Tannast, Moritz

    The Journal of bone and joint surgery. American volume

    2021  Volume 103, Issue 19, Page(s) 1807–1816

    Abstract: Background: Geriatric acetabular fractures are becoming more common due to demographic changes. Compared with proximal femoral fractures, surgical treatment is more complex and often does not allow full-weight-bearing. The aims of this study were to ... ...

    Abstract Background: Geriatric acetabular fractures are becoming more common due to demographic changes. Compared with proximal femoral fractures, surgical treatment is more complex and often does not allow full-weight-bearing. The aims of this study were to compare operatively treated acetabular and proximal femoral fractures with regard to (1) cumulative 1-year mortality, (2) perioperative complications, and (3) predictive factors associated with a higher 1-year mortality.
    Methods: This institutional review board-approved comparative study included 486 consecutive surgically treated elderly patients (136 acetabular and 350 proximal femoral fractures). After matching, 2 comparable groups of 129 acetabular and 129 proximal femoral fractures were analyzed. Cumulative 1-year mortality was evaluated through Kaplan-Meier survivorship analysis, and perioperative complications were documented and graded. After confirming that the proportionality assumption was met, Cox proportional hazard modeling was conducted to identify factors associated with increased 1-year mortality.
    Results: The acetabular fracture group had a significantly lower cumulative 1-year mortality before matching (18% compared with 33% for proximal femoral fractures, log-rank p = 0.001) and after matching (18% compared with 36%, log-rank p = 0.005). Nevertheless, it had a significantly higher overall perioperative complication rate (68% compared with 48%, p < 0.001). In our multivariable Cox regression analysis, older age, perioperative blood loss of >1 L, and wheelchair mobilization were associated with lower survival rates after acetabular fracture surgery. Older age and a higher 5-item modified frailty index were associated with a higher 1-year mortality rate after proximal femoral fractures, whereas postoperative full weight-bearing was protective.
    Conclusions: Despite the complexity of operative treatment and a higher complication rate after acetabular fractures in the elderly, the 1-year mortality rate is lower than that after operative treatment of proximal femoral fractures, even after adjustment for comorbidities.
    Level of evidence: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
    MeSH term(s) Acetabulum/injuries ; Acetabulum/surgery ; Aged ; Aged, 80 and over ; Female ; Fracture Fixation, Internal/methods ; Fracture Fixation, Internal/mortality ; Fractures, Bone/mortality ; Fractures, Bone/surgery ; Hip Fractures/mortality ; Hip Fractures/surgery ; Humans ; Male ; Middle Aged ; Retrospective Studies
    Language English
    Publishing date 2021-06-16
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 220625-0
    ISSN 1535-1386 ; 0021-9355
    ISSN (online) 1535-1386
    ISSN 0021-9355
    DOI 10.2106/JBJS.20.01805
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Conference proceedings: Geriatrische Patienten mit Acetabulumfraktur haben eine niedrigere Ein-Jahres-Mortalität im Vergleich zu proximalen Femurfrakturen – Eine gematchte Fall-Kontrollstudie von 486 Patienten

    Stetzelberger, Vera M. / Brouze, Iris F. / Steppacher, Simon D. / Schwab, Joseph Michael / Bastian, Johannes Dominik / Tannast, Moritz

    2021  , Page(s) AB26–375

    Event/congress Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2021); Berlin; ; Berufsverband für Orthopädie und Unfallchirurgie; 2021
    Keywords Medizin, Gesundheit ; Acetabulumfraktur ; Geriatrische Frakturen ; Proximale Femurfraktur ; Ein-Jahres Mortalität ; Multivariate cox-regression ; Gebrechlichkeit ; Sarkopenie ; Osteoporose ; Charlson comorbidity index ; Kaplan-Meier ; Hüfttotalendoprothese ; Hemiprothese
    Publishing date 2021-10-26
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/21dkou093
    Database German Medical Science

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