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  1. Article ; Online: Quantifying phenology and migratory behaviours of hummingbirds using single-site dynamics and mark-detection analyses.

    English, Simon G / Wilson, Scott / Bandivadekar, Ruta R / Graves, Emily E / Holyoak, Marcel / Brown, Jennifer C / Tell, Lisa A

    Proceedings. Biological sciences

    2022  Volume 289, Issue 1982, Page(s) 20220991

    Abstract: Nuanced understanding of seasonal movements of partially migratory birds is paramount to species and habitat conservation. Using nascent statistical methods, we identified migratory strategies of birds outfitted with radio-frequency identification (RFID) ...

    Abstract Nuanced understanding of seasonal movements of partially migratory birds is paramount to species and habitat conservation. Using nascent statistical methods, we identified migratory strategies of birds outfitted with radio-frequency identification (RFID) tags detected at RFID feeders in two sites in California, USA. We quantified proportions of migrants and residents and the seasonal phenology for each movement strategy in Allen's and Anna's hummingbirds; we also validated our methodology by fitting our model to obligate migratory black-chinned hummingbirds. Allen's and Anna's hummingbirds exhibited characteristics of facultative migratory behaviour. We also quantified apparent annual survival for each migratory strategy and found that residents had significantly higher probabilities of apparent survival. Low survival estimates for migrants suggest that a high proportion of birds in the migrant group permanently emigrated from our study sites. Considered together, our analyses suggest that hummingbirds in both northern and southern California sites partake in diverse and highly plastic migratory behaviours. Our assessment elucidates the dynamics underlying idiosyncratic migratory behaviours of two species of hummingbirds, in addition to describing a framework for similar assessments of migratory behaviours using the multi-state open robust design with state uncertainty model and single-site dynamics.
    MeSH term(s) Animal Migration ; Animals ; Birds ; Ecosystem
    Language English
    Publishing date 2022-09-14
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 209242-6
    ISSN 1471-2954 ; 0080-4649 ; 0962-8452 ; 0950-1193
    ISSN (online) 1471-2954
    ISSN 0080-4649 ; 0962-8452 ; 0950-1193
    DOI 10.1098/rspb.2022.0991
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1364: Show issues Location:
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  2. Article: Response to thyrotropin-releasing hormone (TRH) in a horse with hyperthyroidism associated with a functional thyroid adenoma.

    Costello, Jillian / Firshman, Anna M / Brown, Jennifer C / Maher, Michael / Tadros, Elizabeth M

    The Canadian veterinary journal = La revue veterinaire canadienne

    2019  Volume 60, Issue 11, Page(s) 1189–1193

    Abstract: A 16-year-old American Paint Horse gelding was presented for evaluation of weight loss and high serum thyroid hormone concentrations resulting from a functional thyroid adenoma. The horse showed no response to a thyrotropin-releasing hormone (TRH) ... ...

    Abstract A 16-year-old American Paint Horse gelding was presented for evaluation of weight loss and high serum thyroid hormone concentrations resulting from a functional thyroid adenoma. The horse showed no response to a thyrotropin-releasing hormone (TRH) stimulation test. Clinical signs resolved following surgical removal of the adenoma.
    MeSH term(s) Adenoma/veterinary ; Animals ; Horse Diseases ; Horses ; Hyperthyroidism/veterinary ; Male ; Thyroid Neoplasms/veterinary ; Thyrotropin ; Thyrotropin-Releasing Hormone
    Chemical Substances Thyrotropin-Releasing Hormone (5Y5F15120W) ; Thyrotropin (9002-71-5)
    Language English
    Publishing date 2019-11-06
    Publishing country Canada
    Document type Case Reports
    ZDB-ID 41603-4
    ISSN 0008-5286
    ISSN 0008-5286
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: Correction: Use of RFID technology to characterize feeder visitations and contact network of hummingbirds in urban habitats.

    Bandivadekar, Ruta R / Pandit, Pranav S / Sollmann, Rahel / Thomas, Michael J / Logan, Scott M / Brown, Jennifer C / Peter Klimley, A / Tell, Lisa A

    PloS one

    2019  Volume 14, Issue 1, Page(s) e0211254

    Abstract: This corrects the article DOI: 10.1371/journal.pone.0208057.]. ...

    Abstract [This corrects the article DOI: 10.1371/journal.pone.0208057.].
    Language English
    Publishing date 2019-01-17
    Publishing country United States
    Document type Published Erratum
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0211254
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Use of RFID technology to characterize feeder visitations and contact network of hummingbirds in urban habitats.

    Bandivadekar, Ruta R / Pandit, Pranav S / Sollmann, Rahel / Thomas, Michael J / Logan, Scott M / Brown, Jennifer C / Klimley, A Peter / Tell, Lisa A

    PloS one

    2018  Volume 13, Issue 12, Page(s) e0208057

    Abstract: Despite the popular use of hummingbird feeders, there are limited studies evaluating the effects of congregation, sharing food resources and increased contact when hummingbirds visit feeders in urban landscapes. To evaluate behavioral interactions ... ...

    Abstract Despite the popular use of hummingbird feeders, there are limited studies evaluating the effects of congregation, sharing food resources and increased contact when hummingbirds visit feeders in urban landscapes. To evaluate behavioral interactions occurring at feeders, we tagged 230 individuals of two species, Anna's and Allen's Hummingbirds, with passive integrated transponder tags and recorded their visits with RFID transceivers at feeders. For detecting the presence of tagged birds, we developed an RFID equipped feeding station using a commercially available antenna and RFID transceiver. Data recorded included the number of feeder visits, time spent at the feeder, simultaneous feeder visitation by different individuals, and identifying which feeders were most commonly visited by tagged birds. For the study period (September 2016 to March 2018), 118,017 detections were recorded at seven feeding stations located at three California sites. The rate of tagged birds returning to RFID equipped feeders at least once was 61.3% (141/230 birds). Females stayed at feeders longer than males per visit. We identified primary, secondary and tertiary feeders at Sites 2 and 3, according to the frequency of visitation to them, with a mean percentage of 86.9% (SD±19.13) visits to a primary feeder for each tagged hummingbird. During spring and summer, hummingbirds visited feeders most often in morning and evening hours. Feeder visits by males overlapped in time with other males more frequently than other females. The analysis of the contact network at the feeders did not distinguish any significant differences between age or sex. Although most hummingbirds visited the feeders during the daytime, our system recorded night feeder visitations (n = 7 hummingbirds) at one site. This efficient use of RFID technology to characterize feeder visitations and contact networks of hummingbirds in urban habitats could be used in the future to elucidate behaviors, population dynamics and community structure of hummingbirds visiting feeders.
    MeSH term(s) Animals ; Birds/physiology ; California ; Cities ; Ecological Parameter Monitoring/instrumentation ; Ecological Parameter Monitoring/methods ; Ecosystem ; Feeding Behavior/physiology ; Female ; Male ; Radio Frequency Identification Device ; Remote Sensing Technology/instrumentation ; Sex Factors ; Time Factors
    Language English
    Publishing date 2018-12-12
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0208057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: The glycosphingolipid, lactosylceramide, regulates beta1-integrin clustering and endocytosis.

    Sharma, Deepak K / Brown, Jennifer C / Cheng, Zhijie / Holicky, Eileen L / Marks, David L / Pagano, Richard E

    Cancer research

    2005  Volume 65, Issue 18, Page(s) 8233–8241

    Abstract: Glycosphingolipids are known to play roles in integrin-mediated cell adhesion and migration; however, the mechanisms by which glycosphingolipids affect integrins are unknown. Here, we show that addition of the glycosphingolipid, C8-lactosylceramide (C8- ... ...

    Abstract Glycosphingolipids are known to play roles in integrin-mediated cell adhesion and migration; however, the mechanisms by which glycosphingolipids affect integrins are unknown. Here, we show that addition of the glycosphingolipid, C8-lactosylceramide (C8-LacCer), or free cholesterol to human fibroblasts at 10 degrees C causes the formation of glycosphingolipid-enriched plasma membrane domains as shown by visualizing a fluorescent glycosphingolipid probe, BODIPY-LacCer, incorporated into the plasma membrane of living cells. Addition of C8-LacCer or cholesterol to cells initiated the clustering of beta1-integrins within these glycosphingolipid-enriched domains and the activation of the beta1-integrins as assessed using a HUTS antibody that only binds activated integrin. On warming to 37 degrees C, beta1-integrins were rapidly internalized via caveolar endocytosis in cells treated with C8-LacCer or cholesterol, whereas little beta1-integrin was endocytosed in untreated fibroblasts. Incubation of cells with C8-LacCer or cholesterol followed by warm-up caused src activation, a reorganization of the actin cytoskeleton, translocation of RhoA GTPase away from the plasma membrane as visualized using total internal reflection fluorescence microscopy, and transient cell detachment. These studies show that LacCer can regulate integrin function both by modulating integrin clustering in microdomains and by regulating integrin endocytosis via caveolae. Our findings suggest the possibility that aberrant levels of glycosphingolipids found in cancer cells may influence cell attachment events by direct effects on integrin clustering and internalization.
    MeSH term(s) Caveolae/drug effects ; Caveolae/metabolism ; Cell Adhesion/physiology ; Cell Membrane/drug effects ; Cell Membrane/metabolism ; Cholesterol/metabolism ; Cholesterol/pharmacology ; Endocytosis/drug effects ; Endocytosis/physiology ; Fibroblasts/cytology ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Humans ; Integrin beta1/metabolism ; Lactosylceramides/metabolism ; Lactosylceramides/pharmacology ; Skin/cytology ; rhoA GTP-Binding Protein/metabolism
    Chemical Substances Integrin beta1 ; Lactosylceramides ; Cholesterol (97C5T2UQ7J) ; rhoA GTP-Binding Protein (EC 3.6.5.2)
    Language English
    Publishing date 2005-09-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1432-1
    ISSN 1538-7445 ; 0008-5472
    ISSN (online) 1538-7445
    ISSN 0008-5472
    DOI 10.1158/0008-5472.CAN-05-0803
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  6. Article ; Online: Genetic Mapping of a new

    Siders, Jamie L / Bieser, Kayla L / Hamill, Danielle R / Acosta, Erika C / Alexander, Olivia K / Ali, Humza I / Anderson, Micah J / Arrasmith, Hayden R / Azam, Mustafa / Beeman, Nikki J / Beydoun, Hassan / Bishop, Lauren J / Blair, Morgan D / Bletch, Brianna / Bline, Heather R / Brown, Jennifer C / Burns, Kelly M / Calagua, Karina C / Chafin, Lexie /
    Christy, William Ah / Ciamacco, Carlyn / Cizauskas, Hannah / Colwell, Caitlyn M / Courtright, Abigail R / Diaz Alavez, Lucero / Ecret, Rayne Is / Edriss, Fatima / Ellerbrock, Taylor G / Ellis, Madison M / Extine, Erica M / Feldman, Eric / Fickenworth, Luke J / Goeller, Caroline M / Grogg, Alexis S / Hernandez, Yailine / Hershner, Abigail / Jauss, Megan M / Jimenez Garcia, Leyre / Franks, Katey E / Kazubski, Ethan T / Landis, Emily R / Langub, Jon / Lassek, Tia N / Le, Triet C / Lee, Julia M / Levine, Daniel P / Lightfoot, Phoebe J / Love, Natasha / Maalhagh-Fard, Ali / Maguire, Colin / McGinnis, Brynna E / Mehta, Bhargavi V / Melendrez, Veronica / Mena, Zimri E / Mendell, Seth / Montiel-Garcia, Petra / Murry, Autumn S / Newland, Riley A / Nobles, Ryan M / Patel, Neha / Patil, Yashodhara / Pfister, Cassidy L / Ramage, Victoria / Ray, Mya R / Rodrigues, Joseph / Rodriquez, Victoria C / Romero, Yara / Scott, Alexandra M / Shaba, Nicholas / Sieg, Samantha / Silva, Kayla / Singh, Sahiba / Spargo, Aleksandria J / Spitnale, Savanna J / Sweeden, Nicole / Tague, Logan / Tavernini, Breanna M / Tran, Kathleen / Tungol, Liselle / Vestal, Kylie A / Wetherbee, Amber / Wright, Kayla M / Yeager, Anthony T / Zahid, Rehab / Kagey, Jacob D

    microPublication biology

    2021  Volume 2021

    Abstract: Genetic screens provide a mechanism to identify genes involved with different cellular and organismal processes. Using a Flp/FRT screen in ... ...

    Abstract Genetic screens provide a mechanism to identify genes involved with different cellular and organismal processes. Using a Flp/FRT screen in the
    Language English
    Publishing date 2021-04-08
    Publishing country United States
    Document type Journal Article
    ISSN 2578-9430
    ISSN (online) 2578-9430
    DOI 10.17912/micropub.biology.000383
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Selective stimulation of caveolar endocytosis by glycosphingolipids and cholesterol.

    Sharma, Deepak K / Brown, Jennifer C / Choudhury, Amit / Peterson, Timothy E / Holicky, Eileen / Marks, David L / Simari, Robert / Parton, Robert G / Pagano, Richard E

    Molecular biology of the cell

    2004  Volume 15, Issue 7, Page(s) 3114–3122

    Abstract: Internalization of some plasma membrane constituents, bacterial toxins, and viruses occurs via caveolae; however, the factors that regulate caveolar internalization are still unclear. Here, we demonstrate that a brief treatment of cultured cells with ... ...

    Abstract Internalization of some plasma membrane constituents, bacterial toxins, and viruses occurs via caveolae; however, the factors that regulate caveolar internalization are still unclear. Here, we demonstrate that a brief treatment of cultured cells with natural or synthetic glycosphingolipids (GSLs) or elevation of cholesterol (either by acute treatment with mbeta-cyclodextrin/cholesterol or by alteration of growth conditions) dramatically stimulates caveolar endocytosis with little or no effect on other endocytic mechanisms. These treatments also stimulated the movement of GFP-labeled vesicles in cells transfected with caveolin-1-GFP and reduced the number of surface-connected caveolae seen by electron microscopy. In contrast, overexpression of caveolin-1 decreased caveolar uptake, but treatment with GSLs reversed this effect and stimulated caveolar endocytosis. Stimulation of caveolar endocytosis did not occur using ceramide or phosphatidylcholine and was not due to GSL degradation because similar results were obtained using a nonhydrolyzable GSL analog. Stimulated caveolar endocytosis required src kinase and PKC-alpha activity as shown by i) use of pharmacological inhibitors, ii) expression of kinase inactive src or dominant negative PKCalpha, and iii) stimulation of src kinase activity upon addition of GSLs or cholesterol. These results suggest that caveolar endocytosis is regulated by a balance of caveolin-1, cholesterol, and GSLs at the plasma membrane.
    MeSH term(s) Benzoquinones ; Caveolae/chemistry ; Caveolae/drug effects ; Caveolae/physiology ; Caveolin 1 ; Caveolins/analysis ; Caveolins/genetics ; Caveolins/metabolism ; Cells, Cultured ; Cholesterol/pharmacology ; Cholesterol/physiology ; Endocytosis/drug effects ; Endocytosis/physiology ; Fibroblasts/chemistry ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Gene Expression ; Glycosphingolipids/pharmacology ; Glycosphingolipids/physiology ; Green Fluorescent Proteins/analysis ; Green Fluorescent Proteins/genetics ; Humans ; Lactams, Macrocyclic ; Protein Kinase C/antagonists & inhibitors ; Protein Kinase C/metabolism ; Protein Kinase C-alpha ; Pyrimidines/pharmacology ; Quinones/pharmacology ; Rifabutin/analogs & derivatives ; src-Family Kinases/antagonists & inhibitors ; src-Family Kinases/metabolism
    Chemical Substances AG 1879 ; Benzoquinones ; CAV1 protein, human ; Caveolin 1 ; Caveolins ; Glycosphingolipids ; Lactams, Macrocyclic ; Pyrimidines ; Quinones ; Green Fluorescent Proteins (147336-22-9) ; Rifabutin (1W306TDA6S) ; herbimycin (70563-58-5) ; Cholesterol (97C5T2UQ7J) ; src-Family Kinases (EC 2.7.10.2) ; PRKCA protein, human (EC 2.7.11.13) ; Protein Kinase C (EC 2.7.11.13) ; Protein Kinase C-alpha (EC 2.7.11.13)
    Language English
    Publishing date 2004-07
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 1098979-1
    ISSN 1939-4586 ; 1059-1524
    ISSN (online) 1939-4586
    ISSN 1059-1524
    DOI 10.1091/mbc.E04-03-0189
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 410: Show issues

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