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  1. Article ; Online: Pancreatic Stones and Extracorporeal Shockwave Lithotripsy: A Review of the Literature.

    Gnecco, James / Brown, Landon K / Boregowda, Umesha / Abidali, Hussein / Saligram, Shreyas / Rosenkranz, Laura / Patel, Sandeep / Haluskza, Oleh / Sayana, Hari

    Pancreas

    2022  Volume 51, Issue 8, Page(s) 916–922

    Abstract: Abstract: Pancreatic stones are sequelae of chronic pancreatitis, resulting in poor quality of life, frequent hospitalizations, and a significant economic burden. Extracorporeal shock wave lithotripsy (ESWL) can be used to treat pancreatic stones and is ...

    Abstract Abstract: Pancreatic stones are sequelae of chronic pancreatitis, resulting in poor quality of life, frequent hospitalizations, and a significant economic burden. Extracorporeal shock wave lithotripsy (ESWL) can be used to treat pancreatic stones and is less invasive when compared to other modalities. In this review article, we have discussed the role of ESWL in the treatment of pancreatic stones and how it differs from other modalities. Databases were searched electronically for articles discussing the treatment of pancreatic ductal stones by ESWL or other modalities. Articles discussing or comparing treatment success rates were preferentially included. An inductive approach was used to identify articles related to the treatment of pancreatic stones with ESWL throughout the review process. Although laser lithotripsy and electrohydraulic lithotripsy appear to have higher success rates, the potential for ESWL to affect clinical outcomes is substantial, especially in individuals with a higher risk for invasive procedures. The decision to perform ESWL should be considered if the outcome will substantially alter the clinical management when performed by an experienced endoscopist. Further randomized controlled trials are needed to compare ESWL and peroral pancreatic lithotripsy methods.
    MeSH term(s) Humans ; Quality of Life ; Calculi/therapy ; Calculi/complications ; Lithotripsy/adverse effects ; Lithotripsy/methods ; Pancreatic Diseases/therapy ; Pancreatic Diseases/complications ; Pancreatitis, Chronic/therapy ; Pancreatitis, Chronic/complications ; Treatment Outcome
    Language English
    Publishing date 2022-11-04
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 632831-3
    ISSN 1536-4828 ; 0885-3177
    ISSN (online) 1536-4828
    ISSN 0885-3177
    DOI 10.1097/MPA.0000000000002129
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Rectal ultrasound with fine needle aspiration: an underutilized modality for delineating and diagnosing perirectal, presacral, and pelvic lesions.

    Brown, Landon K / Clark, Norman R / Conway, Jason / Mishra, Girish

    Endoscopy international open

    2019  Volume 7, Issue 2, Page(s) E171–E177

    Abstract: Background and study ... ...

    Abstract Background and study aims
    Language English
    Publishing date 2019-01-18
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2761052-4
    ISSN 2196-9736 ; 2364-3722
    ISSN (online) 2196-9736
    ISSN 2364-3722
    DOI 10.1055/a-0743-5356
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Rectal ultrasound with fine needle aspiration: an underutilized modality for delineating and diagnosing perirectal, presacral, and pelvic lesions

    Brown, Landon K. / Clark, Norman R. / Conway, Jason / Mishra, Girish

    Endoscopy International Open

    2019  Volume 07, Issue 02, Page(s) E171–E177

    Abstract: Background and study aims: The merits of rectal ultrasound for rectal cancer staging are well documented. Conventional approaches to accessing perirectal and presacral lesions entail computed tomography guidance via a transgluteal approach or frank ... ...

    Abstract Background and study aims: The merits of rectal ultrasound for rectal cancer staging are well documented. Conventional approaches to accessing perirectal and presacral lesions entail computed tomography guidance via a transgluteal approach or frank surgical exploration. We report on the safety and efficacy of performing rectal ultrasound with fine-needle aspiration (RUS-FNA) for evaluating perirectal, presacral, and pelvic abnormalities.
    Patients and methods: Patients who underwent RUS-FNA of perirectal, presacral, or pelvic lesions between August 2005 and September 2016 were identified using an institutional database. Subjects were all individuals treated at Wake Forest Baptist Medical Center in Winston-Salem, North Carolina, United States. Patient demographics and imaging characteristics were noted. Procedural details included lesion size, location, echo appearance, and technical information. Patients were given antibiotics prior to FNA attempt and for 3 days after. Diagnostic yield, clinical utility, and complications were noted.
    Results: Twenty-seven patients met criteria during the specified study time period. The cohort consisted of 12 males (44.4 %) and 15 females (55.5 %). RUS-FNA was diagnostic in 24 patients (88.8 %) and obviated the need for surgery in 14 patients (51.9 %). There were four complications (14.8 %): two perirectal and two presacral abscesses.
    Conclusion: While the diagnostic yield of RUS-FNA is high and the potential to affect clinical decision-making is substantial, risk of complication is not negligible. RUS-FNA should only be performed if the result will substantially alter clinical management, and the decision to perform RUS-FNA should be made with close consultation between the endosonographer, surgeon, and/or medical or radiation oncologist.
    Language English
    Publishing date 2019-01-18
    Publisher © Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2761052-4
    ISSN 2196-9736 ; 2364-3722 ; 2196-9736
    ISSN (online) 2196-9736
    ISSN 2364-3722 ; 2196-9736
    DOI 10.1055/a-0743-5356
    Database Thieme publisher's database

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  4. Article ; Online: Symptoms Suggestive of Gastroparesis in a Community-Based Cohort of European Americans and African Americans with Type 2 Diabetes Mellitus.

    Brown, Landon K / Xu, Jianzhao / Freedman, Barry I / Hsu, Fang-Chi / Bowden, Donald W / Koch, Kenneth L

    Digestive diseases and sciences

    2019  Volume 65, Issue 8, Page(s) 2321–2330

    Abstract: Background: Although gastroparesis is seen in patients with type 2 diabetes mellitus (T2DM), the prevalence of symptoms suggestive of gastroparesis in patients with T2DM is unknown, particularly among African Americans.: Aims: To determine the ... ...

    Abstract Background: Although gastroparesis is seen in patients with type 2 diabetes mellitus (T2DM), the prevalence of symptoms suggestive of gastroparesis in patients with T2DM is unknown, particularly among African Americans.
    Aims: To determine the prevalence of symptoms associated with gastroparesis in a large community-based population of European Americans and African Americans with T2DM.
    Methods: Individuals with T2DM in the Diabetes Heart Study were asked to complete the gastroparesis cardinal symptom index (GCSI) and other GI-related questionnaires. GCSI total score ≥ 18 represented moderate or worse symptoms suggestive of gastroparesis.
    Results: A total of 1253 participants (700 female, 553 male) completed the GCSI: 750 were European American and 503 African American. GCSI scores ≥ 18 were recorded in 72 participants: 38 (5%) of European Americans and 34 (7%) of African Americans. The average GCSI was 24.1 in European Americans and 24.6 in African Americans, indicating moderate to severe symptoms. Compared to European Americans with GCSI scores ≥ 18, African Americans were younger (59.4 vs. 53.3 years, p = 0.004), had earlier onset of T2DM (46.3 vs. 40.1 years, p = 0.01), higher HbA1c (7.6 vs. 9.1, p = 0.0009), underwent fewer upper endoscopies (55.3% vs. 26.5%, p = 0.02), and had more anxiety and depression (p < 0.001).
    Conclusions: Moderate or greater symptoms suggestive of gastroparesis are present in 5-7% of European and African American patients with T2DM in community-based populations. Symptoms suggestive of gastroparesis may be underappreciated in patients with T2DM and account for upper gastrointestinal symptoms, unexplained glycemic control issues, and decreased quality of life.
    MeSH term(s) African Americans/statistics & numerical data ; Aged ; Cohort Studies ; Diabetes Mellitus, Type 2/complications ; Female ; Gastroparesis/epidemiology ; Gastroparesis/etiology ; Humans ; Male ; Middle Aged ; North Carolina/epidemiology ; Prevalence ; Severity of Illness Index ; Whites/statistics & numerical data
    Language English
    Publishing date 2019-12-09
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 304250-9
    ISSN 1573-2568 ; 0163-2116
    ISSN (online) 1573-2568
    ISSN 0163-2116
    DOI 10.1007/s10620-019-05974-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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