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  1. Article: Cholera Infantum.

    Brown, Owen

    Buffalo medical and surgical journal

    2023  Volume 3, Issue 2, Page(s) 52–59

    Language English
    Publishing date 2023-01-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 426472-1
    ISSN 1040-3825
    ISSN 1040-3825
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Letter to the editor on "Increased low-frequency brain responses to music after psilocybin therapy for depression".

    Brown, Olivier

    Journal of affective disorders

    2023  Volume 338, Page(s) 135–136

    Abstract: The recent publication in the Journal of Affective Disorders titled "Increased low-frequency brain responses to music after psilocybin therapy for depression" identified significant region-of-interest based effects of treatment in the task scans. In this ...

    Abstract The recent publication in the Journal of Affective Disorders titled "Increased low-frequency brain responses to music after psilocybin therapy for depression" identified significant region-of-interest based effects of treatment in the task scans. In this letter to the editor, I am hoping to raise methodological concerns with regards to the ANOVA ROI analysis that were otherwise not acknowledged in this study. These concerns raise questions as to the impact of confounds, including as age and biological sex, on the reported proportion variance explained by the effects of psilocybin treatment for depression.
    MeSH term(s) Humans ; Psilocybin/pharmacology ; Psilocybin/therapeutic use ; Hallucinogens/therapeutic use ; Depression/drug therapy ; Music/psychology ; Brain/diagnostic imaging
    Chemical Substances Psilocybin (2RV7212BP0) ; Hallucinogens
    Language English
    Publishing date 2023-05-29
    Publishing country Netherlands
    Document type Journal Article ; Comment
    ZDB-ID 135449-8
    ISSN 1573-2517 ; 0165-0327
    ISSN (online) 1573-2517
    ISSN 0165-0327
    DOI 10.1016/j.jad.2023.05.088
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The James Truman Dental Society of the University of Pennsylvania.

    Brown, O M

    International dental journal (Philadelphia, Pa.)

    2023  Volume 12, Issue 4, Page(s) 256–258

    Language English
    Publishing date 2023-11-01
    Publishing country United States
    Document type Journal Article
    ISSN 1069-0441
    ISSN 1069-0441
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The provision of a trauma bed in theatre recovery and its impact on trauma theatre efficiency: experience from a high-volume trauma unit.

    Saleem, J / Brown, O / Mclean, C / Kurzatkowski, K / Radha, S / Mallina, R

    Annals of the Royal College of Surgeons of England

    2024  

    Abstract: Introduction: Inefficiencies in the trauma setting are well known and have been further exacerbated by the COVID-19 pandemic among other factors, resulting in national guidance to aid improvements in resource utilisation. This study introduced a novel ... ...

    Abstract Introduction: Inefficiencies in the trauma setting are well known and have been further exacerbated by the COVID-19 pandemic among other factors, resulting in national guidance to aid improvements in resource utilisation. This study introduced a novel surgeon-led intervention, a trauma bed in recovery, with the aim of improving trauma theatre efficiency.
    Methods: This quality improvement project was conducted using a Plan Do Study Act (PDSA) methodology and comprised multiple cycles to assess theatre performance. A multidisciplinary team (MDT) approach with relevant stakeholder input enabled intervention implementation, aimed at facilitating 'golden patient' arrival in the anaesthetic room as early as possible. The primary outcome was the time at which the first patient entered the anaesthetic room, and the secondary outcome was the number of cases performed each day.
    Results: The study period was 1 year and encompassed three PDSA cycles. The intervention achieved its primary outcome by PDSA cycle 1 and its secondary outcome by PDSA cycle 2, demonstrating statistically significantly improved results (
    Conclusions: A ringfenced trauma bed significantly improved theatre start times and thereby theatre efficiency. This is a simple, pragmatic intervention that benefitted the MDT trauma team while also demonstrating a sustained impact. Given that National Health Service efficiency is at the forefront of national healthcare discourse, we recommend that this intervention is implemented in other trauma units to help provide a solution to this longstanding issue.
    Language English
    Publishing date 2024-02-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 80044-2
    ISSN 1478-7083 ; 0035-8843
    ISSN (online) 1478-7083
    ISSN 0035-8843
    DOI 10.1308/rcsann.2023.0106
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Fear-avoidant beliefs and behaviours after upper limb fracture in older people: a systematic review and meta-ethnography.

    Smith, Toby O / Brown, Oliver / Baxter, Mark A

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

    2024  

    Abstract: Purpose: This systematic review aimed to understand older people's perspectives of associated fear-avoidant beliefs following upper limb fracture.: Methods: Published and unpublished literature databases were systematically searched from inception to ...

    Abstract Purpose: This systematic review aimed to understand older people's perspectives of associated fear-avoidant beliefs following upper limb fracture.
    Methods: Published and unpublished literature databases were systematically searched from inception to 1st April 2023. Qualitative studies reporting the perspectives of fear-avoidant beliefs or behaviours in people who had sustained an upper limb fracture were eligible. Data extracted included characteristics of people interviewed, experiences and perceptions of fear, fear of falling, and fear-avoidant beliefs and behaviours. Data were synthesised using a meta-ethnography approach and the GRADE-CERQUAL tool.
    Results: Eight studies were eligible (n = 150 participants; 109 distal radial/41 humeral fracture). Three overarching themes were identified: (1) type of fear-avoidant experiences, (2) drivers of fear-avoidant beliefs and behaviours, and (3) consequences of fear-avoidant beliefs and behaviours. The themes generated were based on moderate confidence evidence. In summary, whilst some patients initially consider upper limb fractures to be relatively minor injuries, over time, the realisation occurs that they have wide-ranging consequences with longer-term perspectives on recovery. This often occurs following an initial period of reduced fear. Providing education and support immediately post-fracture to prevent or challenge initial health beliefs around fear of falls and fear of movement is imperative to recovery.
    Conclusions: Fear-avoidant beliefs can impact heavily on certain older people's recovery, as well as their longer-term health and wellbeing. Consideration of fear avoidance and taking steps to mitigate against this in the acute upper limb trauma setting will better serve these patients in their ongoing recovery from injury.
    Language English
    Publishing date 2024-01-27
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1064892-6
    ISSN 1433-2965 ; 0937-941X
    ISSN (online) 1433-2965
    ISSN 0937-941X
    DOI 10.1007/s00198-024-07030-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Head-torso coordination in police officers wearing loaded tactical vests during running.

    Ellison, M A / Gorman, A J / Brown, O / Mullineaux, D R / Mulloy, F

    Gait & posture

    2023  Volume 107, Page(s) 28–34

    Abstract: Background: The influence of load carriage in operational police officers is not well understood despite a relatively high injury rate. Assessing load related changes in head and torso coordination may provide valuable insight into plausible injury ... ...

    Abstract Background: The influence of load carriage in operational police officers is not well understood despite a relatively high injury rate. Assessing load related changes in head and torso coordination may provide valuable insight into plausible injury mechanisms.
    Research question: Do typical police tactical vest loads alter head and torso coordination during running?
    Methods: Thirty-eight UK police officers ran at a self-selected pace (>2 ms
    Results: No significant differences were found between conditions for peak head or torso tilt alone (p > 0.05). Loading equipment low on the vest led to significantly greater mediolateral vest displacements (38 mm) away from the torso than a high (34 mm) or evenly distributed (30 mm) conditions. The vest was found to change direction vertically before the torso in the anterior-posterior direction, and then influence torso motion. The loaded conditions changed the head-torso coupling from in-phase (with head-dominancy) to anti-phase (with torso dominancy) between 55% and 77% stance. Anti-phase with a relatively stationary head and the torso rotating forward likely places a greater concentric demand on the posterior neck muscles relative to unloaded running.
    Significance: Current tactical vest designs allow significant extra displacement of load away from the body during running, altering coordination at the head and torso.
    MeSH term(s) Humans ; Police ; Torso/physiology ; Exercise Test ; Running/physiology ; Motion
    Language English
    Publishing date 2023-09-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 1162323-8
    ISSN 1879-2219 ; 0966-6362
    ISSN (online) 1879-2219
    ISSN 0966-6362
    DOI 10.1016/j.gaitpost.2023.09.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Editorial: Naturalistic decision making (NDM): epistemic expertise in action.

    Gore, Julie / Shortland, Neil / Power, Nicola / Brown, Olivia

    Frontiers in psychology

    2023  Volume 14, Page(s) 1303098

    Language English
    Publishing date 2023-11-10
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2023.1303098
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Ketamine for Treatment of Posttraumatic Stress Disorder: State of the Field.

    Fremont, Rachel / Brown, Oneysha / Feder, Adriana / Murrough, James

    Focus (American Psychiatric Publishing)

    2023  Volume 21, Issue 3, Page(s) 257–265

    Abstract: Posttraumatic stress disorder (PTSD) is a chronic and debilitating condition. Although several psychotherapeutic and pharmacological treatments are recommended for PTSD, many individuals do not respond to treatment or respond only partially, highlighting ...

    Abstract Posttraumatic stress disorder (PTSD) is a chronic and debilitating condition. Although several psychotherapeutic and pharmacological treatments are recommended for PTSD, many individuals do not respond to treatment or respond only partially, highlighting a critical need for additional treatments. Ketamine has the potential to address this therapeutic need. This review discusses how ketamine emerged as a rapid-acting antidepressant and has become a potential treatment for PTSD. A single dose of intravenous (IV) ketamine has been shown to facilitate rapid reduction of PTSD symptoms. Repeated IV ketamine administration significantly improved PTSD symptoms, compared with midazolam, in a predominantly civilian sample of individuals with PTSD. However, in a veteran and military population, repeated IV ketamine did not significantly reduce PTSD symptoms. Further study of ketamine as a treatment for PTSD is necessary, including which populations benefit most from this therapy and the potential benefits of combining psychotherapy and ketamine.
    Language English
    Publishing date 2023-06-28
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1541-4094
    ISSN 1541-4094
    DOI 10.1176/appi.focus.20230006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Invited Commentary.

    Brown, O William

    Annals of vascular surgery

    2018  Volume 51, Page(s) 29–30

    MeSH term(s) Malpractice ; Surgeons
    Language English
    Publishing date 2018-06-13
    Publishing country Netherlands
    Document type Journal Article ; Comment
    ZDB-ID 1027366-9
    ISSN 1615-5947 ; 0890-5096
    ISSN (online) 1615-5947
    ISSN 0890-5096
    DOI 10.1016/j.avsg.2018.02.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Invited commentary.

    Brown, O William

    Journal of vascular surgery. Venous and lymphatic disorders

    2018  Volume 6, Issue 4, Page(s) 544–545

    Language English
    Publishing date 2018
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2213-3348
    ISSN (online) 2213-3348
    DOI 10.1016/j.jvsv.2018.02.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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