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  1. Book ; Thesis: Epidemiologie, Auxiologie und klinisch-bildgebende Diagnostik der Pubertas praecox in Costa Rica im Zeitraum Januar 2008 bis Januar 2015

    Aguilar Valdés, Abner Daniel / Brune, Thomas / Holterhus, Paul-Martin

    2019  

    Title variant zweitausendacht, zweitausendfünfzehn
    Institution Otto-von-Guericke-Universität Magdeburg
    Author's details vorgelegt von Abner Daniel Aguilar Valdés aus San José, Costa Rica ; Gutachter: Thomas Brune ; Paul-Martin Holterhus
    Keywords Pubertas praecox ; Costa Rica
    Subject Virilismus
    Language German
    Size 91 Blätter, Diagramme
    Publishing place Magdeburg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität Magdeburg, 2020
    HBZ-ID HT020527153
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2020 E 1135 order for loan Magazin

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  2. Book ; Thesis: Autologes Plazentablut für die Therapie anämischer Früh- und Reifgeborener

    Brune, Thomas

    2004  

    Author's details vorgelegt von Thomas Brune
    Language German
    Size 76 Bl., Ill., graph. Darst., 30 cm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Magdeburg, Univ., Habil.-Schr., 2004
    Note Erscheinungsjahr auf der Haupttitels.: 2003
    HBZ-ID HT014836773
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2006 E 1470 order to use in reading room Magazin

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  3. Book ; Thesis: Nutzen und Möglichkeiten der Proliferationsbestimmung beim Ovarialkarzinom mit dem Antikörper MIB1

    Brune, Thomas

    1996  

    Author's details vorgelegt von Thomas Brune geb. Grubisic
    Language German
    Size 73 Bl. : graph. Darst.
    Edition [Mikrofiche-Ausg.]
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Göttingen, Univ., Diss., 1997
    Note Mikrofiche-Ausg.: 1 Mikrofiches : 24x
    HBZ-ID HT009421926
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1998 MB 2578 order for loan Magazin

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  4. Article ; Online: COVID-19 in pregnancy with comorbidities: More liberal testing strategy is needed.

    Gidlöf, Sebastian / Savchenko, Julia / Brune, Thomas / Josefsson, Hampus

    Acta obstetricia et gynecologica Scandinavica

    2020  Volume 99, Issue 7, Page(s) 948–949

    MeSH term(s) Adult ; Betacoronavirus/isolation & purification ; COVID-19 ; COVID-19 Testing ; Cesarean Section/methods ; Clinical Laboratory Techniques/methods ; Clinical Laboratory Techniques/standards ; Comorbidity ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/physiopathology ; Coronavirus Infections/therapy ; Diabetes, Gestational/diagnosis ; Diabetes, Gestational/epidemiology ; Female ; Humans ; Hypertension/diagnosis ; Hypertension/epidemiology ; Pandemics ; Patient Care Management/methods ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/physiopathology ; Pneumonia, Viral/therapy ; Pre-Eclampsia/diagnosis ; Pre-Eclampsia/epidemiology ; Pre-Eclampsia/physiopathology ; Pre-Eclampsia/therapy ; Pregnancy ; Pregnancy Complications/epidemiology ; Pregnancy Complications/physiopathology ; Pregnancy Complications/therapy ; Pregnancy Outcome ; Pregnancy, High-Risk ; Pregnancy, Twin ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-04-17
    Publishing country United States
    Document type Letter
    ZDB-ID 80019-3
    ISSN 1600-0412 ; 0001-6349
    ISSN (online) 1600-0412
    ISSN 0001-6349
    DOI 10.1111/aogs.13862
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Um I Zs.168: Show issues Location:
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  5. Article ; Online: Comprehensive analysis of yeast ESCRT-III composition in single ESCRT-III deletion mutants.

    Heinzle, Christian / Mücke, Lara / Brune, Thomas / Kölling, Ralf

    The Biochemical journal

    2019  Volume 476, Issue 14, Page(s) 2031–2046

    Abstract: The endosomal sorting complex required for transport (ESCRT)-III is associated with a multitude of cellular processes involving membrane remodeling and abscission. The exact composition of ESCRT-III and the contribution of individual ESCRT-III family ... ...

    Abstract The endosomal sorting complex required for transport (ESCRT)-III is associated with a multitude of cellular processes involving membrane remodeling and abscission. The exact composition of ESCRT-III and the contribution of individual ESCRT-III family members to these diverse functions is unclear. Most of the currently available information about ESCRT-III was obtained with tagged, largely non-functional proteins, which may not correctly reflect the
    MeSH term(s) Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Endoplasmic Reticulum/genetics ; Endoplasmic Reticulum/metabolism ; Endosomal Sorting Complexes Required for Transport/genetics ; Endosomal Sorting Complexes Required for Transport/metabolism ; Gene Deletion ; Protein Transport/genetics ; Rabbits ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism
    Chemical Substances Adaptor Proteins, Signal Transducing ; Chm7 protein, S cerevisiae ; DID2 protein, S cerevisiae ; Endosomal Sorting Complexes Required for Transport ; Saccharomyces cerevisiae Proteins
    Language English
    Publishing date 2019-07-24
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2969-5
    ISSN 1470-8728 ; 0006-2936 ; 0306-3275 ; 0264-6021
    ISSN (online) 1470-8728
    ISSN 0006-2936 ; 0306-3275 ; 0264-6021
    DOI 10.1042/BCJ20190141
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.110: Show issues Location:
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  6. Book ; Thesis: Spätergebnisse nach Ellbogenluxation

    Brune, Thomas

    1988  

    Size 104 S. : Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis München, Techn. Univ., Diss., 1988
    HBZ-ID HT003340244
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    89 D 4876 order for loan Magazin

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  7. Book ; Conference proceedings: Hin und her - Dialoge in Museen zur Alltagskultur

    Brune, Thomas / Stieglitz, Leo von

    aktuelle Positionen zur Besucherpartizipation ; [Beiträge zur 20. Tagung in Waldenbuch vom 29. November bis 1. Dezember 2012]

    (Edition Museum ; 9)

    2015  

    Event/congress Tagung (20, 2012.11.29-12.01, Waldenbuch)
    Author's details Leo von Stieglitz, Thomas Brune (Hg.)
    Series title Edition Museum ; 9
    Keywords Museum exhibits/Social aspects ; Museum visitors ; Museums/Educational aspects ; Museums/Social aspects ; Alltagskultur ; Publikum ; Partizipation ; Museum
    Language German
    Size 140 S., Ill, 225 mm x 148 mm, 273 g
    Publisher transcript
    Publishing place Bielefeld
    Document type Book ; Conference proceedings
    Note Literaturangaben
    ISBN 3837627616 ; 9783837627619 ; 9783839427613 ; 3839427614
    Database Former special subject collection: coastal and deep sea fishing

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  8. Article: Interactions in the ESCRT-III network of the yeast Saccharomyces cerevisiae

    Brune, Thomas / Heike Kunze-Schumacher / Ralf Kölling

    Current genetics. 2019 Apr., v. 65, no. 2

    2019  

    Abstract: Here, we examine the genetic interactions between ESCRT-III mutations in the yeast Saccharomyces cerevisiae. From the obtained interaction network, we make predictions about alternative ESCRT-III complexes. By the successful generation of an octuple ... ...

    Abstract Here, we examine the genetic interactions between ESCRT-III mutations in the yeast Saccharomyces cerevisiae. From the obtained interaction network, we make predictions about alternative ESCRT-III complexes. By the successful generation of an octuple deletion strain using the CRISPR/Cas9 technique, we demonstrate for the first time that ESCRT-III activity as a whole is not essential for the life of a yeast cell. Endosomal sorting complex required for transport (ESCRT)-III proteins are membrane remodeling factors involved in a multitude of cellular processes. There are eight proteins in yeast with an ESCRT-III domain. It is not clear whether the diverse ESCRT-III functions are fulfilled by a single ESCRT-III complex or by different complexes with distinct composition. Genetic interaction studies may provide a hint on the existence of alternative complexes. We performed a genetic mini-array screen by analyzing the growth phenotypes of all pairwise combinations of ESCRT-III deletion mutations under different stress conditions. Our analysis is in line with previous data pointing to a complex containing Did2/CHMP1 and Ist1/IST1. In addition, we provide evidence for the existence of a novel complex consisting of Did2/CHMP1 and Vps2/CHMP2. Some of the interactions on Congo red plates could be explained by effects of ESCRT-III mutations on Rim101 signaling.
    Keywords Saccharomyces cerevisiae ; mutation ; phenotype ; prediction ; proteins ; yeasts
    Language English
    Dates of publication 2019-04
    Size p. 607-619.
    Publishing place Springer Berlin Heidelberg
    Document type Article
    ZDB-ID 282876-5
    ISSN 1432-0983 ; 0172-8083
    ISSN (online) 1432-0983
    ISSN 0172-8083
    DOI 10.1007/s00294-018-0915-8
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 81/707: Show issues

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  9. Article ; Online: Interactions in the ESCRT-III network of the yeast Saccharomyces cerevisiae.

    Brune, Thomas / Kunze-Schumacher, Heike / Kölling, Ralf

    Current genetics

    2018  Volume 65, Issue 2, Page(s) 607–619

    Abstract: Here, we examine the genetic interactions between ESCRT-III mutations in the yeast Saccharomyces cerevisiae. From the obtained interaction network, we make predictions about alternative ESCRT-III complexes. By the successful generation of an octuple ... ...

    Abstract Here, we examine the genetic interactions between ESCRT-III mutations in the yeast Saccharomyces cerevisiae. From the obtained interaction network, we make predictions about alternative ESCRT-III complexes. By the successful generation of an octuple deletion strain using the CRISPR/Cas9 technique, we demonstrate for the first time that ESCRT-III activity as a whole is not essential for the life of a yeast cell. Endosomal sorting complex required for transport (ESCRT)-III proteins are membrane remodeling factors involved in a multitude of cellular processes. There are eight proteins in yeast with an ESCRT-III domain. It is not clear whether the diverse ESCRT-III functions are fulfilled by a single ESCRT-III complex or by different complexes with distinct composition. Genetic interaction studies may provide a hint on the existence of alternative complexes. We performed a genetic mini-array screen by analyzing the growth phenotypes of all pairwise combinations of ESCRT-III deletion mutations under different stress conditions. Our analysis is in line with previous data pointing to a complex containing Did2/CHMP1 and Ist1/IST1. In addition, we provide evidence for the existence of a novel complex consisting of Did2/CHMP1 and Vps2/CHMP2. Some of the interactions on Congo red plates could be explained by effects of ESCRT-III mutations on Rim101 signaling.
    MeSH term(s) CRISPR-Cas Systems ; Endosomal Sorting Complexes Required for Transport/metabolism ; Endosomes/metabolism ; Epistasis, Genetic ; Gene Deletion ; Mutation ; Phenotype ; Protein Binding ; Protein Transport ; Saccharomyces cerevisiae/drug effects ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism
    Chemical Substances Endosomal Sorting Complexes Required for Transport
    Language English
    Publishing date 2018-12-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 282876-5
    ISSN 1432-0983 ; 0172-8083
    ISSN (online) 1432-0983
    ISSN 0172-8083
    DOI 10.1007/s00294-018-0915-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: COVID-19 in pregnancy with comorbidities: More liberal testing strategy is needed

    Gidlöf, Sebastian / Savchenko, Julia / Brune, Thomas / Josefsson, Hampus

    Acta Obstet Gynecol Scand

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #34979
    Database COVID19

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