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  1. Article ; Online: Simulation as a Tool to Ensure Competency and Quality of Care in the Cardiac Critical Care Unit.

    Brunette, Véronique / Thibodeau-Jarry, Nicolas

    The Canadian journal of cardiology

    2017  Volume 33, Issue 1, Page(s) 119–127

    Abstract: Cardiac critical care units are high-risk clinical environments. Medical emergencies are frequent and require the intervention of a cohesive, efficient, and well trained interprofessional team. In modern clinical practice there is increased emphasis on ... ...

    Abstract Cardiac critical care units are high-risk clinical environments. Medical emergencies are frequent and require the intervention of a cohesive, efficient, and well trained interprofessional team. In modern clinical practice there is increased emphasis on safety but also increased lack of acceptance of medical errors and as a consequence, increased litigation. In the past decade, simulation-based learning has arisen as an effective and safe means to learn and practice acute care setting skills. It has been used and studied in different contexts including procedural skills training, crisis resource management and team training, patient and family member communication skills, and health care system quality improvement. Simulation-based education is a relatively recent teaching strategy and evidence of its efficacy continues to grow. Nevertheless, many influential medical societies are now promoting a simulation-based approach for cardiovascular training and continuing medical education. In this article we review the simulation literature in the intensive care unit and evaluate its integration in coronary care units and postoperative cardiovascular intensive care units. We also provide resources for educators and clinicians who wish to implement simulation workshops in these settings.
    MeSH term(s) Clinical Competence ; Computer Simulation ; Coronary Care Units ; Critical Care/standards ; Education, Medical, Continuing/methods ; Humans ; Quality Assurance, Health Care
    Language English
    Publishing date 2017-01
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 632813-1
    ISSN 1916-7075 ; 0828-282X
    ISSN (online) 1916-7075
    ISSN 0828-282X
    DOI 10.1016/j.cjca.2016.10.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Individualizing Cerebral Perfusion Pressure Targets.

    Bernard, Francis / Albert, Martin / Brunette, Véronique

    Critical care medicine

    2018  Volume 46, Issue 2, Page(s) e175

    MeSH term(s) Cerebrovascular Circulation ; Homeostasis ; Intracranial Pressure ; Perfusion
    Language English
    Publishing date 2018-02-14
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000002792
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Prelicensure Simulation-Enhanced Interprofessional Education: A Critical Review of the Research Literature.

    Palaganas, Janice C / Brunette, Veronique / Winslow, Betty

    Simulation in healthcare : journal of the Society for Simulation in Healthcare

    2016  Volume 11, Issue 6, Page(s) 404–418

    Abstract: Statement: This review explores the state of prelicensure interprofessional education (IPE) using simulation-based education (SBE) by examining studies that use SBE for prelicensure IPE through a critical review of the research literature. We focus ... ...

    Abstract Statement: This review explores the state of prelicensure interprofessional education (IPE) using simulation-based education (SBE) by examining studies that use SBE for prelicensure IPE through a critical review of the research literature. We focus particularly on studies that included experiential SBE with reported measures and formal IPE with prelicensure participants from at least 2 health care professions. Fifty-four studies met criteria. We explore these studies, providing a compilation of information (e.g., educational, simulation, and research methods used; outcome measures reported; and demographics of learner groups), identifying themes that may affect learning, as well as surfacing challenges and gaps in the field. The quality and rigor of the existing literature is inadequate to confidently determine factors that affect learning through simulation-enhanced IPE. We suggest that more rigorous research criteria be included in future studies and a list of reporting items be provided, where future publications can enhance knowledge to guide best practice in simulation-enhanced IPE.
    MeSH term(s) Education, Medical/methods ; Humans ; Interprofessional Relations ; Licensure ; Simulation Training
    Language English
    Publishing date 2016-12
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2223429-9
    ISSN 1559-713X ; 1559-2332
    ISSN (online) 1559-713X
    ISSN 1559-2332
    DOI 10.1097/SIH.0000000000000175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Venoarterial Extracorporeal Membrane Oxygenation Support for Severe Pericardial Decompression Syndrome: A Case Report.

    Ricarte Bratti, Juan P / Brunette, Veronique / Lebon, Jean S / Pellerin, Michel / Lamarche, Yoan

    Critical care medicine

    2019  Volume 48, Issue 1, Page(s) e74–e75

    Abstract: Objectives: We report a case of a man with tamponade decompression syndrome following pericardial drainage.: Data sources: ICU - Montreal Heart Institute.: Study selection: Case report.: Data extraction: Clinical and surgical records.: Data ... ...

    Abstract Objectives: We report a case of a man with tamponade decompression syndrome following pericardial drainage.
    Data sources: ICU - Montreal Heart Institute.
    Study selection: Case report.
    Data extraction: Clinical and surgical records.
    Data synthesis: None.
    Conclusions: Our case adds further concerns in supporting a patient with tamponade decompression syndrome, including mechanical circulatory support, due to the reversible nature of this condition.
    MeSH term(s) Aged ; Arteries ; Cardiac Tamponade/therapy ; Combined Modality Therapy ; Drainage ; Extracorporeal Membrane Oxygenation/methods ; Humans ; Male ; Severity of Illness Index ; Syndrome ; Veins
    Language English
    Publishing date 2019-09-26
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000004046
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Early experience with critically ill patients with COVID-19 in Montreal.

    Cavayas, Yiorgos Alexandros / Noël, Alexandre / Brunette, Veronique / Williamson, David / Frenette, Anne Julie / Arsenault, Christine / Bellemare, Patrick / Lagrenade-Verdant, Colin / LeGuillan, Soazig / Levesque, Emilie / Lamarche, Yoan / Giasson, Marc / Rico, Philippe / Beaulieu, Yanick / Marsolais, Pierre / Serri, Karim / Bernard, Francis / Albert, Martin

    Canadian journal of anaesthesia = Journal canadien d'anesthesie

    2020  Volume 68, Issue 2, Page(s) 204–213

    Abstract: Purpose: Montreal has been the epicentre of the coronavirus disease (COVID-19) pandemic in Canada. Given the regional disparities in incidence and mortality in the general population, we aimed to describe local characteristics, treatments, and outcomes ... ...

    Title translation Expériences initiales avec les patients atteints de la COVID-19 en état critique à Montréal.
    Abstract Purpose: Montreal has been the epicentre of the coronavirus disease (COVID-19) pandemic in Canada. Given the regional disparities in incidence and mortality in the general population, we aimed to describe local characteristics, treatments, and outcomes of critically ill COVID-19 patients in Montreal.
    Methods: A single-centre retrospective cohort of consecutive adult patients admitted to the intensive care unit (ICU) of Hôpital du Sacré-Coeur de Montréal with confirmed COVID-19 were included.
    Results: Between 20 March and 13 May 2020, 75 patients were admitted, with a median [interquartile range (IQR)] age of 62 [53-72] yr and high rates of obesity (47%), hypertension (67%), and diabetes (37%). Healthcare-related infections were responsible for 35% of cases. The median [IQR] day 1 sequential organ failure assessment score was 6 [3-7]. Invasive mechanical ventilation (IMV) was used in 57% of patients for a median [IQR] of 11 [5-22] days. Patients receiving IMV were characterized by a moderately decreased median [IQR] partial pressure of oxygen:fraction of inspired oxygen (day 1 PaO
    Conclusions: Characteristics and outcomes of critically ill patients with COVID-19 in Montreal were similar to those reported in the existing literature. We found an increased physiologic dead space, supporting the hypothesis that pulmonary vascular injury may be central to COVID-19-induced lung damage.
    MeSH term(s) Aged ; Aged, 80 and over ; COVID-19/mortality ; COVID-19/physiopathology ; COVID-19/therapy ; Canada ; Critical Illness ; Female ; Hospital Mortality ; Humans ; Male ; Middle Aged ; Respiration, Artificial ; Retrospective Studies
    Keywords covid19
    Language English
    Publishing date 2020-09-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 91002-8
    ISSN 1496-8975 ; 0832-610X
    ISSN (online) 1496-8975
    ISSN 0832-610X
    DOI 10.1007/s12630-020-01816-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Acute Kidney Injury and Renal Recovery with the Use of Aminoglycosides: A Large Retrospective Study.

    Paquette, François / Bernier-Jean, Amélie / Brunette, Véronique / Ammann, Hélène / Lavergne, Valéry / Pichette, Vincent / Troyanov, Stéphan / Bouchard, Josée

    Nephron

    2015  Volume 131, Issue 3, Page(s) 153–160

    Abstract: Background: Recent acute kidney injury (AKI) guidelines, based on studies performed a decade ago, recommend avoiding aminoglycosides (AGs) in patients at risk of AKI. Whether present patient characteristics and management have changed this risk is ... ...

    Abstract Background: Recent acute kidney injury (AKI) guidelines, based on studies performed a decade ago, recommend avoiding aminoglycosides (AGs) in patients at risk of AKI. Whether present patient characteristics and management have changed this risk is uncertain. We determined the current incidence, risk factors and outcomes of AG-AKI.
    Methods: We retrospectively identified adult patients who received gentamicin or tobramycin for ≥5 days in 2 large university-affiliated centers, excluding critically ill and dialysis patients. We assessed the incidence of Risk, Injury, Failure, Loss and End-stage kidney disease criteria of AKI risk and then matched each AKI to 2 controls of same age and gender to determine factors associated with AG-AKI and its recovery, defined by a creatinine within 150% of baseline by 21 days.
    Results: Since 2001, the frequency of AG administration and dosing declined, but the incidence of AG-AKI remained constant. Of the 562 patients who received AG for ≥5 days, 65 (12%) developed AG-AKI after 11 (IQR 8-15) days, with 56, 29 and 15% having stages 1, 2 and 3 AKI, respectively. We matched these to 130 controls. In this nested case-control study, independent AKI risk factors were vancomycin coadministration, high AG trough levels and heart failure. AG-AKI compared to AG exposure without AKI was associated with greater mortality. Renal recovery occurred in 51% of the AKI patients and was less likely with heart failure and higher AKI severity.
    Conclusion: AG administration has recently decreased but the risk of AKI remained unchanged and half of the patients did not recover. Vancomycin coadministration, high AG trough levels and heart failure independently predicted AKI.
    MeSH term(s) Acute Kidney Injury/chemically induced ; Acute Kidney Injury/mortality ; Acute Kidney Injury/physiopathology ; Aged ; Aged, 80 and over ; Aminoglycosides/adverse effects ; Antineoplastic Agents/adverse effects ; Case-Control Studies ; Creatinine/blood ; Female ; Gentamicins/adverse effects ; Heart Failure/complications ; Humans ; Kidney/physiopathology ; Kidney Failure, Chronic/chemically induced ; Kidney Failure, Chronic/physiopathology ; Male ; Middle Aged ; Recovery of Function ; Renal Insufficiency/chemically induced ; Renal Insufficiency/physiopathology ; Retrospective Studies ; Risk Factors ; Tobramycin/adverse effects ; Treatment Outcome ; Vancomycin/adverse effects
    Chemical Substances Aminoglycosides ; Antineoplastic Agents ; Gentamicins ; Vancomycin (6Q205EH1VU) ; Creatinine (AYI8EX34EU) ; Tobramycin (VZ8RRZ51VK)
    Language English
    Publishing date 2015
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 207121-6
    ISSN 2235-3186 ; 1423-0186 ; 1660-8151 ; 0028-2766
    ISSN (online) 2235-3186 ; 1423-0186
    ISSN 1660-8151 ; 0028-2766
    DOI 10.1159/000440867
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Expériences initiales avec les patients atteints de la COVID-19 en état critique à Montréal./ Early experience with critically ill patients with COVID-19 in Montreal

    Cavayas, Yiorgos Alexandros / Noël, Alexandre / Brunette, Veronique / Williamson, David / Frenette, Anne Julie / Arsenault, Christine / Bellemare, Patrick / Lagrenade-Verdant, Colin / LeGuillan, Soazig / Levesque, Emilie / Lamarche, Yoan / Giasson, Marc / Rico, Philippe / Beaulieu, Yanick / Marsolais, Pierre / Serri, Karim / Bernard, Francis / Albert, Martin

    Can. j. anaesth

    Abstract: PURPOSE: Montreal has been the epicentre of the coronavirus disease (COVID-19) pandemic in Canada. Given the regional disparities in incidence and mortality in the general population, we aimed to describe local characteristics, treatments, and outcomes ... ...

    Abstract PURPOSE: Montreal has been the epicentre of the coronavirus disease (COVID-19) pandemic in Canada. Given the regional disparities in incidence and mortality in the general population, we aimed to describe local characteristics, treatments, and outcomes of critically ill COVID-19 patients in Montreal. METHODS: A single-centre retrospective cohort of consecutive adult patients admitted to the intensive care unit (ICU) of Hôpital du Sacré-Coeur de Montréal with confirmed COVID-19 were included. RESULTS: Between 20 March and 13 May 2020, 75 patients were admitted, with a median [interquartile range (IQR)] age of 62 [53-72] yr and high rates of obesity (47%), hypertension (67%), and diabetes (37%). Healthcare-related infections were responsible for 35% of cases. The median [IQR] day 1 sequential organ failure assessment score was 6 [3-7]. Invasive mechanical ventilation (IMV) was used in 57% of patients for a median [IQR] of 11 [5-22] days. Patients receiving IMV were characterized by a moderately decreased median [IQR] partial pressure of oxygen:fraction of inspired oxygen (day 1 PaO2:FiO2 = 177 [138-276]; day 10 = 173 [147-227]) and compliance (day 1 = 48 [38-58] mL/cmH2O; day 10 = 34 [28-42] mL/cmH2O) and very elevated estimated dead space fraction (day 1 = 0.60 [0.53-0.67]; day 10 = 0.72 [0.69-0.79]). Overall hospital mortality was 25%, and 21% in the IMV patients. Mortality was 82% in patients ≥ 80 yr old. CONCLUSIONS: Characteristics and outcomes of critically ill patients with COVID-19 in Montreal were similar to those reported in the existing literature. We found an increased physiologic dead space, supporting the hypothesis that pulmonary vascular injury may be central to COVID-19-induced lung damage.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #758319
    Database COVID19

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  8. Article ; Online: Early experience with critically ill patients with COVID-19 in Montreal

    Cavayas, Yiorgos Alexandros / Noël, Alexandre / Brunette, Veronique / Williamson, David / Frenette, Anne Julie / Arsenault, Christine / Bellemare, Patrick / Lagrenade-Verdant, Colin / LeGuillan, Soazig / Levesque, Emilie / Lamarche, Yoan / Giasson, Marc / Rico, Philippe / Beaulieu, Yanick / Marsolais, Pierre / Serri, Karim / Bernard, Francis / Albert, Martin

    Canadian Journal of Anesthesia/Journal canadien d'anesthésie ; ISSN 0832-610X 1496-8975

    2020  

    Keywords Anesthesiology and Pain Medicine ; General Medicine ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    DOI 10.1007/s12630-020-01816-z
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Acute Kidney Injury and Renal Recovery with the Use of Aminoglycosides: A Large Retrospective Study

    Paquette, François / Bernier-Jean, Amélie / Brunette, Véronique / Ammann, Hélène / Lavergne, Valéry / Pichette, Vincent / Troyanov, Stéphan / Bouchard, Josée

    Nephron

    2015  Volume 131, Issue 3, Page(s) 153–160

    Abstract: Background: Recent acute kidney injury (AKI) guidelines, based on studies performed a decade ago, recommend avoiding aminoglycosides (AGs) in patients at risk of AKI. Whether present patient characteristics and management have changed this risk is ... ...

    Institution Division of Nephrology and Division of Internal Medicine, Department of Medicine Department of Medical Biology and Division of Medical Microbiology and Infectious Diseases, Department of Medical Biology, Sacre-Coeur Hospital of Montreal Division of Nephrology, Department of Medicine, Maisonneuve-Rosemont Hospital, Montreal, Que., Canada
    Abstract Background: Recent acute kidney injury (AKI) guidelines, based on studies performed a decade ago, recommend avoiding aminoglycosides (AGs) in patients at risk of AKI. Whether present patient characteristics and management have changed this risk is uncertain. We determined the current incidence, risk factors and outcomes of AG-AKI. Methods: We retrospectively identified adult patients who received gentamicin or tobramycin for ≥5 days in 2 large university-affiliated centers, excluding critically ill and dialysis patients. We assessed the incidence of Risk, Injury, Failure, Loss and End-stage kidney disease criteria of AKI risk and then matched each AKI to 2 controls of same age and gender to determine factors associated with AG-AKI and its recovery, defined by a creatinine within 150% of baseline by 21 days. Results: Since 2001, the frequency of AG administration and dosing declined, but the incidence of AG-AKI remained constant. Of the 562 patients who received AG for ≥5 days, 65 (12%) developed AG-AKI after 11 (IQR 8-15) days, with 56, 29 and 15% having stages 1, 2 and 3 AKI, respectively. We matched these to 130 controls. In this nested case-control study, independent AKI risk factors were vancomycin coadministration, high AG trough levels and heart failure. AG-AKI compared to AG exposure without AKI was associated with greater mortality. Renal recovery occurred in 51% of the AKI patients and was less likely with heart failure and higher AKI severity. Conclusion: AG administration has recently decreased but the risk of AKI remained unchanged and half of the patients did not recover. Vancomycin coadministration, high AG trough levels and heart failure independently predicted AKI.
    Keywords Acute kidney injury ; Aminoglycoside ; Gentamicin ; Outcomes ; Renal recovery ; Tobramycin
    Language English
    Publishing date 2015-09-22
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    Note Clinical Practice: Original Paper
    ZDB-ID 207121-6
    ISSN 2235-3186 ; 1423-0186 ; 1660-8151 ; 0028-2766
    ISSN (online) 2235-3186 ; 1423-0186
    ISSN 1660-8151 ; 0028-2766
    DOI 10.1159/000440867
    Database Karger publisher's database

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