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Article: Divergent Trends in the Prevalence of Children's Asthma, Rhinitis and Atopic Dermatitis and Environmental Influences in the Urban Setting of Zagreb, Croatia.

Topalušić, Iva / Stipić Marković, Asja / Artuković, Marinko / Dodig, Slavica / Bucić, Lovro / Lugović Mihić, Liborija

2022 Volume 9, Issue 12

Abstract: Background: Previous studies have reported that the allergy epidemic in developed countries has reached its plateau, while a rise is expected in developing ones. Our aim was to compare the prevalence of allergic diseases among schoolchildren from the ... ...

Abstract	Background: Previous studies have reported that the allergy epidemic in developed countries has reached its plateau, while a rise is expected in developing ones. Our aim was to compare the prevalence of allergic diseases among schoolchildren from the city of Zagreb, Croatia after sixteen years. Methods: Symptoms of asthma, allergic rhinitis (AR) and atopic dermatitis (AD) and risk factors were assessed using the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire. An allergic profile was determined by a skin prick test. Results: The prevalence of current, ever-in-a-lifetime and diagnosed AR of 35.7%, 42.5% and 14.9% and AD of 18.1%, 37.1% and 31.1% demonstrated a significant increase. The asthma prevalence has remained unchanged. The allergen sensitivity rate has remained similar, but pollens have become dominant. Mould and dog exposure are risks for asthma (OR 14.505, OR 2.033). Exposure to cat allergens is protective in AR (OR 0.277). Parental history of allergies is a risk factor in all conditions. Conclusion: Over sixteen years, the prevalence of AR and AD, but not of asthma, have increased. The proportion of atopy has remained high. The AR/AD symptom rise is probably a consequence of increased pollen sensitisation united with high particulate matter concentrations. The stable asthma trend could be a result of decreasing exposures to indoor allergens.
Language	English
Publishing date	2022-11-22
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2732685-8
ISSN	2227-9067
ISSN	2227-9067
DOI	10.3390/children9121788
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Psychosocial risks emerged from COVID-19 pandemic and workers' mental health.

Koren, Helena / Milaković, Marina / Bubaš, Marija / Bekavac, Petra / Bekavac, Barbara / Bucić, Lovro / Čvrljak, Jelena / Capak, Magdalena / Jeličić, Pavle

Frontiers in psychology

2023 Volume 14, Page(s) 1148634

Abstract: This paper examines the impact of work in a pandemic context on workers' mental health. Psychosocial risks have always been a challenging aspect of workplace health and safety practices. Moreover, the COVID-19 pandemic has affected workplaces in all ... ...

Abstract	This paper examines the impact of work in a pandemic context on workers' mental health. Psychosocial risks have always been a challenging aspect of workplace health and safety practices. Moreover, the COVID-19 pandemic has affected workplaces in all sectors causing unexpected changes in work organization and working conditions, leading to the emergence of new psychosocial risks for health and wellbeing of workers. This mini-review aims to identify the main work stressors during pandemic period and related mental health problems to suggest recommendations and adjust health and safety practices regarding workplace mental health. A literature search has been performed using MEDLINE/PubMed, ResearchGate and Google Scholar databases, selecting articles focusing on work-related stressors and workers' mental health problems related to the pandemic. Specific psychosocial risks have been identified, including fear of contagion, telework-related risks, isolation and stigmatization, rapid digitalization demands, job insecurity, elevated risk of violence at work or home, and work-life imbalance, among others. All those risks can lead to elevated levels of stress among workers and affect their mental health and wellbeing, especially in terms of psychological distress, anxiety, and depression. As one of the social determinants of health, the workplace has an important and moderating role in workers' health. Therefore, in the pandemic context more than ever health protection practices at the workplace should be devoted to mental health problems. Recommendations provided in this study are expected to contribute to workplace practices to preserve and promote workers' mental health.
Language	English
Publishing date	2023-05-26
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2563826-9
ISSN	1664-1078
ISSN	1664-1078
DOI	10.3389/fpsyg.2023.1148634
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Article ; Online: Telework-related risk factors for musculoskeletal disorders.

Milaković, Marina / Koren, Helena / Bradvica-Kelava, Karmen / Bubaš, Marija / Nakić, Josipa / Jeličić, Pavle / Bucić, Lovro / Bekavac, Barbara / Čvrljak, Jelena / Capak, Magdalena

Frontiers in public health

2023 Volume 11, Page(s) 1155745

Abstract: Telework has become considerably more common during the ongoing pandemic. Although working remotely may have numerous advantages, negative impacts on workers' health and safety should also be considered. Telework is a major contributor to the development ...

Abstract	Telework has become considerably more common during the ongoing pandemic. Although working remotely may have numerous advantages, negative impacts on workers' health and safety should also be considered. Telework is a major contributor to the development or aggravation of work-related musculoskeletal disorders where unsuited workstation ergonomics, sedentary behavior, as well as psychosocial and organizational factors play a role. This paper aims to identify telework-related risks and their impact on musculoskeletal health as well as provide recommendations that may be useful in constructing future preventive measures. A comprehensive literature search regarding the topic has been performed. Teleworkers experience musculoskeletal pain and discomfort mostly in low back area, neck, shoulders, arms, and hands. Poor ergonomic solutions when it comes to workstation design resulting in prolonged sitting in non-neutral positions contribute to the development and aggravation of musculoskeletal disorders in teleworkers. Working with inadequately placed screens and laptops and sitting in maladjusted seats without usual functionalities and ergonomic support is associated with musculoskeletal pain and discomfort. Extended working hours with fewer rest periods to meet increased work demands, social isolation, and lack of support from work colleagues and superiors as well as blurred work-home boundaries and omnipresence of work are commonly stated psychosocial and organizational factors associated with musculoskeletal disorders. Environmental factors such as poor lighting and glare, inadequate room temperature, and ventilation or noise, are frequently overlooked remote workstation risk factors. For a certain part of workers, telework will remain a common way of work in the post-pandemic period. Therefore, it is essential to identify telework-related risk factors for musculoskeletal disorders and address them with timely preventive measures tailored to each remote workstation's risks and individual workers' needs.
MeSH term(s)	Humans ; Musculoskeletal Pain ; Teleworking ; Risk Factors ; Ergonomics/methods ; Occupational Health
Language	English
Publishing date	2023-07-03
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2023.1155745
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Article ; Online: Surveillance system for coronavirus disease 2019 epidemiological parameters in Croatia.

Capak, Krunoslav / Kopal, Robert / Benjak, Tomislav / Cerovečki, Ivan / Draušnik, Željka / Bucić, Lovro / Pristaš, Ivan / Curać, Jelena

Croatian medical journal

2021 Volume 61, Issue 6, Page(s) 481–482

MeSH term(s)	COVID-19/epidemiology ; Croatia/epidemiology ; Humans ; Incidence ; Public Health Surveillance/methods ; SARS-CoV-2
Language	English
Publishing date	2021-01-06
Publishing country	Croatia
Document type	Editorial
ZDB-ID	1157623-6
ISSN	1332-8166 ; 0353-9504
ISSN (online)	1332-8166
ISSN	0353-9504
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: The Emergence of SARS-CoV-2 within the Dog Population in Croatia: Host Factors and Clinical Outcome

Stevanovic, Vladimir / Tabain, Irena / Vilibic-Cavlek, Tatjana / Mauric Maljkovic, Maja / Benvin, Iva / Hruskar, Zeljka / Kovac, Snjezana / Smit, Iva / Miletic, Gorana / Hadina, Suzana / Staresina, Vilim / Radin, Lada / Plichta, Valentina / Skrlin, Branimir / Vrbanac, Zoran / Brkljacic, Mirna / Cvetnic, Marija / Habus, Josipa / Martinkovic, Kresimir /

Zecevic, Iva / Jurkic, Gabrijela / Ferencak, Ivana / Stritof, Zinka / Perharic, Matko / Bucic, Lovro / Barbic, Ljubo

Viruses. 2021 July 22, v. 13, no. 8

2021

Abstract: Over a year into the COVID-19 pandemic, there is growing evidence that SARS-CoV-2 infections among dogs are more common than previously thought. In this study, the prevalence of SARS-CoV-2 antibodies was investigated in two dog populations. The first ... ...

Abstract	Over a year into the COVID-19 pandemic, there is growing evidence that SARS-CoV-2 infections among dogs are more common than previously thought. In this study, the prevalence of SARS-CoV-2 antibodies was investigated in two dog populations. The first group was comprised of 1069 dogs admitted to the Veterinary Teaching Hospital for any given reason. The second group included dogs that shared households with confirmed COVID-19 cases in humans. This study group numbered 78 dogs. In COVID-19 infected households, 43.9% tested ELISA positive, and neutralising antibodies were detected in 25.64% of dogs. Those data are comparable with the secondary attack rate in the human population. With 14.69% of dogs in the general population testing ELISA positive, there was a surge of SARS-CoV-2 infections within the dog population amid the second wave of the pandemic. Noticeably seroprevalence of SARS-CoV-2 in the dog and the human population did not differ at the end of the study period. Male sex, breed and age were identified as significant risk factors. This study gives strong evidence that while acute dog infections are mostly asymptomatic, they can pose a significant risk to dog health. Due to the retrospective nature of this study, samples for viral isolation and PCR were unavailable. Still, seropositive dogs had a 1.97 times greater risk for developing central nervous symptoms.
Keywords	COVID-19 infection ; Severe acute respiratory syndrome coronavirus 2 ; dogs ; hospitals ; human population ; males ; pandemic ; secondary attack rate ; seroprevalence ; Croatia
Language	English
Dates of publication	2021-0722
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2516098-9
ISSN	1999-4915
ISSN	1999-4915
DOI	10.3390/v13081430
Database	NAL-Catalogue (AGRICOLA)

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Article: Emerging Trends in the Epidemiology of COVID-19: The Croatian ‘One Health’ Perspective

Vilibic-Cavlek, Tatjana / Stevanovic, Vladimir / Brlek-Gorski, Diana / Ferencak, Ivana / Ferenc, Thomas / Ujevic-Bosnjak, Magdalena / Tabain, Irena / Janev-Holcer, Natasa / Perkovic, Ivana / Anticevic, Mario / Bekavac, Barbara / Kaic, Bernard / Mrzljak, Anna / Ganjto, Marin / Zmak, Ljiljana / Mauric Maljkovic, Maja / Jelicic, Pavle / Bucic, Lovro / Barbic, Ljubo

Viruses. 2021 Nov. 24, v. 13, no. 12

2021

Abstract: During the four pandemic waves, a total of 560,504 cases and 10,178 deaths due to COVID-19 were reported in Croatia. The Alpha variant, dominant from March 2021 (>50% of positive samples), was rapidly replaced by Delta variants (>90%) by August 2021. ... ...

Abstract	During the four pandemic waves, a total of 560,504 cases and 10,178 deaths due to COVID-19 were reported in Croatia. The Alpha variant, dominant from March 2021 (>50% of positive samples), was rapidly replaced by Delta variants (>90%) by August 2021. Several seroprevalence studies were conducted in different populations (general population, children/adolescents, professional athletes, healthcare workers, veterinarians) and in immunocompromised patients (hemodialysis patients, liver/kidney transplant recipients). After the first pandemic wave, seroprevalence rates of neutralizing (NT) antibodies were reported to be 0.2–5.5%. Significantly higher seropositivity was detected during/after the second wave, 2.6–18.7%. Two studies conducted in pet animals (February-June 2020/July–December 2020) reported SARS-CoV-2 NT antibodies in 0.76% of cats and 0.31–14.69% of dogs, respectively. SARS-CoV-2 NT antibodies were not detected in wildlife. Environmental samples taken in the households of COVID-19 patients showed high-touch personal objects as most frequently contaminated (17.3%), followed by surfaces in patients’ rooms (14.6%), kitchens (13.3%) and bathrooms (8.3%). SARS-CoV-2 RNA was also detected in 96.8% affluent water samples, while all effluent water samples tested negative. Detection of SARS-CoV-2 in humans, animals and the environment suggests that the ‘One Health’ approach is critical to controlling COVID-19 and future pandemics.
Keywords	COVID-19 infection ; RNA ; Severe acute respiratory syndrome coronavirus 2 ; health services ; hemodialysis ; kidney transplant ; liver ; pandemic ; seroprevalence ; wildlife ; Croatia
Language	English
Dates of publication	2021-1124
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2516098-9
ISSN	1999-4915
ISSN	1999-4915
DOI	10.3390/v13122354
Database	NAL-Catalogue (AGRICOLA)

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Article: SARS-CoV-2 Seroprevalence and Neutralizing Antibody Response after the First and Second COVID-19 Pandemic Wave in Croatia

Pathogens. 2021 June 20, v. 10, no. 6

2021

Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus with a pandemic spread. So far, a total of 349,910 SARS-CoV-2 cases and 7687 deaths were reported in Croatia. We analyzed the seroprevalence and neutralizing (NT) ... ...

Abstract	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus with a pandemic spread. So far, a total of 349,910 SARS-CoV-2 cases and 7687 deaths were reported in Croatia. We analyzed the seroprevalence and neutralizing (NT) antibody response in the Croatian general population after the first (May–July 2020) and second (December 2020–February 2021) pandemic wave. Initial serological testing was performed using a commercial ELISA, with confirmation of reactive samples by a virus neutralization test (VNT). A significant difference in the overall seroprevalence rate was found after the first (ELISA 2.2%, VNT 0.2%) and second waves (ELISA 25.1%, VNT 18.7%). Seropositive individuals were detected in all age groups, with significant differences according to age. The lowest prevalence of NT antibodies was documented in the youngest (<10 years; 16.1%) and the oldest (60–69/70+ years; 16.0% and 12.8%, respectively) age groups. However, these age groups showed the highest median NT titers (32–64). In other groups, seropositivity varied from 19.3% to 21.5%. A significant weak positive correlation between binding antibody level as detected by ELISA and VNT titer (rho = 0.439, p < 0.001) was observed. SARS-CoV-2 NT antibody titers seem to be age-related, with the highest NT activity in children under 10 years and individuals above 50 years.
Keywords	COVID-19 infection ; Severe acute respiratory syndrome coronavirus 2 ; antibody formation ; neutralization tests ; pandemic ; seroprevalence ; Croatia
Language	English
Dates of publication	2021-0620
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2695572-6
ISSN	2076-0817
ISSN	2076-0817
DOI	10.3390/pathogens10060774
Database	NAL-Catalogue (AGRICOLA)

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Article: SARS-CoV-2 Seroprevalence and Neutralizing Antibody Response after the First and Second COVID-19 Pandemic Wave in Croatia.

Pathogens (Basel, Switzerland)

2021 Volume 10, Issue 6

Abstract	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus with a pandemic spread. So far, a total of 349,910 SARS-CoV-2 cases and 7687 deaths were reported in Croatia. We analyzed the seroprevalence and neutralizing (NT) antibody response in the Croatian general population after the first (May-July 2020) and second (December 2020-February 2021) pandemic wave. Initial serological testing was performed using a commercial ELISA, with confirmation of reactive samples by a virus neutralization test (VNT). A significant difference in the overall seroprevalence rate was found after the first (ELISA 2.2%, VNT 0.2%) and second waves (ELISA 25.1%, VNT 18.7%). Seropositive individuals were detected in all age groups, with significant differences according to age. The lowest prevalence of NT antibodies was documented in the youngest (<10 years; 16.1%) and the oldest (60-69/70+ years; 16.0% and 12.8%, respectively) age groups. However, these age groups showed the highest median NT titers (32-64). In other groups, seropositivity varied from 19.3% to 21.5%. A significant weak positive correlation between binding antibody level as detected by ELISA and VNT titer (rho = 0.439,
Language	English
Publishing date	2021-06-20
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2695572-6
ISSN	2076-0817
ISSN	2076-0817
DOI	10.3390/pathogens10060774
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The Emergence of SARS-CoV-2 within the Dog Population in Croatia: Host Factors and Clinical Outcome.

Zecevic, Iva / Jurkic, Gabrijela / Ferencak, Ivana / Stritof, Zinka / Perharic, Matko / Bucic, Lovro / Barbic, Ljubo

Viruses

2021 Volume 13, Issue 8

Abstract	Over a year into the COVID-19 pandemic, there is growing evidence that SARS-CoV-2 infections among dogs are more common than previously thought. In this study, the prevalence of SARS-CoV-2 antibodies was investigated in two dog populations. The first group was comprised of 1069 dogs admitted to the Veterinary Teaching Hospital for any given reason. The second group included dogs that shared households with confirmed COVID-19 cases in humans. This study group numbered 78 dogs. In COVID-19 infected households, 43.9% tested ELISA positive, and neutralising antibodies were detected in 25.64% of dogs. Those data are comparable with the secondary attack rate in the human population. With 14.69% of dogs in the general population testing ELISA positive, there was a surge of SARS-CoV-2 infections within the dog population amid the second wave of the pandemic. Noticeably seroprevalence of SARS-CoV-2 in the dog and the human population did not differ at the end of the study period. Male sex, breed and age were identified as significant risk factors. This study gives strong evidence that while acute dog infections are mostly asymptomatic, they can pose a significant risk to dog health. Due to the retrospective nature of this study, samples for viral isolation and PCR were unavailable. Still, seropositive dogs had a 1.97 times greater risk for developing central nervous symptoms.
MeSH term(s)	Animals ; Antibodies, Viral/blood ; COVID-19/blood ; COVID-19/epidemiology ; COVID-19/veterinary ; COVID-19/virology ; Communicable Diseases, Emerging/blood ; Communicable Diseases, Emerging/epidemiology ; Communicable Diseases, Emerging/veterinary ; Communicable Diseases, Emerging/virology ; Croatia/epidemiology ; Dog Diseases/blood ; Dog Diseases/diagnosis ; Dog Diseases/epidemiology ; Dog Diseases/virology ; Dogs ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Male ; Pandemics ; Retrospective Studies ; SARS-CoV-2/immunology ; SARS-CoV-2/isolation & purification ; Seroepidemiologic Studies
Chemical Substances	Antibodies, Viral
Language	English
Publishing date	2021-07-22
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2516098-9
ISSN	1999-4915 ; 1999-4915
ISSN (online)	1999-4915
ISSN	1999-4915
DOI	10.3390/v13081430
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Emerging Trends in the Epidemiology of COVID-19: The Croatian 'One Health' Perspective.

Viruses

2021 Volume 13, Issue 12

Abstract	During the four pandemic waves, a total of 560,504 cases and 10,178 deaths due to COVID-19 were reported in Croatia. The Alpha variant, dominant from March 2021 (>50% of positive samples), was rapidly replaced by Delta variants (>90%) by August 2021. Several seroprevalence studies were conducted in different populations (general population, children/adolescents, professional athletes, healthcare workers, veterinarians) and in immunocompromised patients (hemodialysis patients, liver/kidney transplant recipients). After the first pandemic wave, seroprevalence rates of neutralizing (NT) antibodies were reported to be 0.2-5.5%. Significantly higher seropositivity was detected during/after the second wave, 2.6-18.7%. Two studies conducted in pet animals (February-June 2020/July-December 2020) reported SARS-CoV-2 NT antibodies in 0.76% of cats and 0.31-14.69% of dogs, respectively. SARS-CoV-2 NT antibodies were not detected in wildlife. Environmental samples taken in the households of COVID-19 patients showed high-touch personal objects as most frequently contaminated (17.3%), followed by surfaces in patients' rooms (14.6%), kitchens (13.3%) and bathrooms (8.3%). SARS-CoV-2 RNA was also detected in 96.8% affluent water samples, while all effluent water samples tested negative. Detection of SARS-CoV-2 in humans, animals and the environment suggests that the 'One Health' approach is critical to controlling COVID-19 and future pandemics.
MeSH term(s)	Animals ; Antibodies, Neutralizing ; Antibodies, Viral ; COVID-19/epidemiology ; COVID-19/transmission ; COVID-19/veterinary ; COVID-19/virology ; Cats ; Croatia/epidemiology ; Dogs ; Genetic Variation ; Health Personnel ; Humans ; One Health ; Pandemics ; Pets ; Prevalence ; RNA, Viral ; SARS-CoV-2/genetics ; SARS-CoV-2/isolation & purification ; Seroepidemiologic Studies ; Wastewater/virology
Chemical Substances	Antibodies, Neutralizing ; Antibodies, Viral ; RNA, Viral ; Waste Water
Language	English
Publishing date	2021-11-24
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	2516098-9
ISSN	1999-4915 ; 1999-4915
ISSN (online)	1999-4915
ISSN	1999-4915
DOI	10.3390/v13122354
Database	MEDical Literature Analysis and Retrieval System OnLINE

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